Search clinical trials for: LCI699 matching placebo

Total 54443 results

Equilibre Biopharmaceuticals B.V.

Terminated

Study of EQU-001 for Uncontrolled Focal Onset Seizures

Focal Onset Seizures

United States, Israel
Merit E. Cudkowicz, MD
Clene Nanomedicine

Completed

HEALEY ALS Platform Trial - Regimen C CNM-Au8

Amyotrophic Lateral Sclerosis

United States
Bayer

Completed

Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack (PACIFIC-AMI)

Acute Myocardial Infarction

Spain, Japan, Belgium, United States, Czechia, Hungary, Switzerland, Netherlands, Germany, Austria, Poland, Italy, Sweden, United Kingdom
Astellas Pharma Global Development, Inc.

Terminated

A Study to Find a Suitable Dose of ASP8731 and Check for Medical Problems at Each Dose in Healthy Adults

Healthy Participants

United States
Janssen Pharmaceutical K.K.

Completed

A Study of JNJ-40411813 in Healthy Japanese Male Participants

Healthy

Japan
Kangpu Biopharmaceuticals, Ltd.

Completed

Safety, Tolerability and Pharmacokinetics of KPG-818 in Healthy Subjects

Systemic Lupus Erythematosus

United States
Merck Sharp & Dohme LLC

Completed

Single Rising Dose Study of MK-8723 in Healthy Participants and Participants With Immune Thrombocytopenia Purpura (MK-8723-001)

Immune Thrombocytopenia Purpura
Axikin Pharmaceuticals, Inc.

Completed

A Phase IIa Repeat Dose AXP1275 vs Placebo Cross-over Trial With Pulmonary Allergen Challenge in Adults With Asthma

Atopic Asthma

Canada
Topokine Therapeutics, Inc.

Unknown

Phase 2 Study of TAT4 Gel for Reduction of Nasolabial Folds

Nasolabial Folds

United States
Glenmark Pharmaceuticals Ltd. India
Glenmark Pharmaceuticals S.A.

Completed

A Clinical Trial to Study the Effects GRC 17536 in Patients With Painful Diabetic Peripheral Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients).

Painful Diabetic Peripheral Neuropathy

India, Czech Republic, Germany, United Kingdom
Boehringer Ingelheim

Completed

Single Rising Oral Doses of BI 1021958 in Healthy Chinese and Japanese Male Volunteers

Healthy

Korea, Republic of
RSPR Pharma AB

Completed

CRD007 for the Treatment of Abdominal Aorta Aneurysm (The AORTA Trial)

Abdominal Aortic Aneurysm

Sweden, United Kingdom, Denmark
Kubota Vision Inc.

Completed

Safety and Tolerability of ACU-4429

Healthy

United States
Addex Pharma S.A.

Completed

ADX10059 as a Monotherapy in Patients With Gastroesophageal Reflux (GERD)

Gastroesophageal Reflux

Austria, Belgium, France, Germany
ChemoCentryx
Medpace, Inc.

Completed

Controlled Trial Evaluating Avacopan in C3 Glomerulopathy (ACCOLADE)

C3 Glomerulopathy (C3G)

United States, Spain, France, Netherlands, Belgium, Canada, Denmark, Germany, Ireland, Italy, United Kingdom
Cognition Therapeutics
National Institute on Aging (NIA)

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

Mild to Moderate Alzheimer's Disease

United States, Australia, Netherlands, Czechia, Spain
9 Meters Biopharma, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms

Celiac Disease

United States
Daiichi Sankyo Co., Ltd.

Completed

Study of Mirogabalin for Central Neuropathic Pain

Central Neuropathic Pain

Japan, Korea, Republic of, Taiwan
Respivert Ltd

Completed

A Study to Investigate the Safety and Tolerability of a New Inhaled Formulation of RV568 in Healthy Volunteers

Healthy Volunteers | COPD

United Kingdom
Boehringer Ingelheim

Completed

Single Rising Dose Study of BI 207127 NA in Healthy Male Asian Volunteers and Single Dose Study of BI 207127 NA in Healthy Male Caucasian Volunteers

Healthy

Korea, Republic of
Cognition Therapeutics
National Institute on Aging (NIA); Alzheimer's Clinical Trials Consortium

Recruiting

A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

Early Alzheimer's Disease

United States
Gmax Biopharm Australia Pty Ltd.

Completed

Assessment of the Safety, Tolerability, and Pharmacokinetic of GMA106

Overweight and Obesity

Australia
Novartis Pharmaceuticals

Recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis

Israel, United States, Canada, United Kingdom
Biogen
Denali Therapeutics Inc.

Recruiting

A Study to Assess the Safety of BIIB122 Tablets and if it Can Slow the Worsening of Early-Stage Parkinson's Disease in Participants Between the Ages of 30 and 80 (LUMA)

Parkinson Disease

United States, Netherlands, Italy, Spain, Israel, Canada, China, Germany, France, Austria, United Kingdom, Poland, Japan
AbbVie

Recruiting

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

Migraine

United States, Puerto Rico
Celldex Therapeutics

Active, not recruiting

A Study of CDX-0159 in Patients With Chronic Inducible Urticaria

Chronic Inducible Urticaria

United States, Latvia, Spain, Poland, Georgia, South Africa, Germany, Lithuania, Estonia, Hungary, Bulgaria
Celldex Therapeutics

Active, not recruiting

A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

Spain, United States, Poland, Georgia, South Africa, Bulgaria, Hungary, Estonia, Germany
Biogen
Denali Therapeutics Inc.

Terminated

A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (LIGHTHOUSE)

Parkinson Disease

United States, Italy, Spain, Germany, France, United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

Single Oral Dose of 4 mg Cenerimod in Healthy Japanese and Caucasian Subjects

Healthy Volunteers

United States
Alzheon Inc.
Quotient Clinical

Completed

Multiple Ascending Dose Study of ALZ-801

Alzheimer Disease

United Kingdom
GlaxoSmithKline

Completed

To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334

Substance Dependence

United Kingdom
Beech Tree Labs, Inc.
Norwich Clinical Research Associates Ltd.; Hill Top Research

Completed

Evaluation of Cold Sore Treatments on Ultra Violet (UV) Induced Cold Sores

Oral Herpes Simplex

United States
Beech Tree Labs, Inc.
Norwich Clinical Research Associates Ltd.

Completed

Safety and Efficacy Study of a New Treatment for Recurrent Symptoms of Oral Herpes Virus Infection

Oral Herpes Simplex

United States
Midnight Pharma, LLC

Completed

Almorexant (ACT-078573) in Elderly Subjects With Chronic Primary Insomnia

Chronic Primary Insomnia

United States
Syneos Health

Recruiting

First-in-Human Study of VB0004 in Healthy Subjects and to Patients With Mild to Moderate Hypertension With Low Cardiovascular Risk

Hypertension

Australia
Karyopharm Therapeutics Inc
Belgium and Luxembourg Gynaecological Oncology Group; North-Eastern German... and other collaborators

Active, not recruiting

Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO] (ENGOT-EN5)

Endometrial Cancer

United States, China, Israel, Spain, Belgium, Germany, Greece, Czechia, Italy, Canada
Institut de Recherches Internationales Servier

Active, not recruiting

Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)

Recurrent Glioma | Grade 2 Glioma | Residual Glioma

United States, Canada, Spain, Italy, United Kingdom, Switzerland, Israel, Japan, Netherlands, Germany, France
Nathura S.p.A
Evidilya S.r.l.

Completed

A New Class IIb MD in Proctological Disorders

Proctological Disorders

Italy
Regeneron Pharmaceuticals

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Effects of a Single Dose of REGN5713-5714-5715 in Healthy Adult Participants

Healthy Volunteers | Birch Pollen Allergy

Belgium
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Tolerability of Repeat Doses of ACU-4429 in Healthy Subjects

Healthy

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Completed

Evaluation of 611 in Chinese Adults With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

China
Takeda

Completed

Single-Dose Study of MT203

Healthy Volunteers

Japan
Novartis Pharmaceuticals

Completed

Safety and Efficacy of LCI699 in Cushing's Disease Patients

Cushings Disease | Cushing Disease

United States, Italy, France, Japan
Biogen

Enrolling by invitation

A Study to Evaluate the Continuous Safety and Efficacy of Litifilimab (BIIB059) in Adults With Active Systemic Lupus Erythematosus (EMERALD)

Systemic Lupus Erythematosus (SLE)

Spain, Bulgaria, United States, China, Serbia, Mexico, Korea, Republic of, Chile, Argentina, Poland, Japan, Romania, Colombia, Hungary, Czechia, United Kingdom, Taiwan, Philippines, Brazil, Israel, France
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics of GSK3923868 Inhalation Powder in Healthy Participants and Stable Asthmatics

Pulmonary Disease, Chronic Obstructive

United Kingdom
GTx

Withdrawn

Durability Extension Study to Assess Clinical Activity and Safety of Enobosarm (GTx-024) in Stress Urinary Incontinence

Stress Urinary Incontinence

United States
AstraZeneca

Completed

Study With CIN-107 Following Multiple Oral Ascending Doses in Healthy Subjects

Hypertension

United States
Boehringer Ingelheim

Completed

A Study to Test How Healthy Women Tolerate Different Doses of BI 1819479

Healthy

Germany
Cyclerion Therapeutics

Terminated

Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type I or II Achalasia

Achalasia

United States
Boehringer Ingelheim

Completed

Single Rising Dose Study of BI 135585 XX in Health Asian Male Volunteers.

Healthy

Korea, Republic of

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