Search clinical trials for: metformin HCl

Total 4838 results

Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone

Diabetes Mellitus Type 2

United States, Mexico, Argentina
Hadassah Medical Organization

Withdrawn

Open-label Crossover Metformin Gum Versus Tablet in Healthy Volunteers

Healthy

Israel
Garvan Institute of Medical Research
Weizmann Institute of Science

Active, not recruiting

Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes (PREDICT)

Type 2 Diabetes Mellitus | Pre Diabetes

Australia
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Becker's Muscular Dystrophy

Becker's Muscular Dystrophy (BMD)

Switzerland
Jiangsu HengRui Medicine Co., Ltd.

Completed

The Drug-drug Interaction of SHR3824 and Metformin

Type 2 Diabetes
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Poland, United Kingdom, Germany, Romania, Hungary, Denmark, Lithuania
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

Glioma | Astrocytoma | Oligodendroglioma

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase III Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes

China
German Diabetes Center
Yale University

Enrolling by invitation

"The Role of the Liver for Interorgan Metabolic Crosstalk in Type 2 Diabetes"

Type2 Diabetes

Germany
RenJi Hospital

Completed

The Effect of Metformin on Reducing Lupus Flares (Met Lupus)

Systemic Lupus Erythematosus

China
Laboratorios Silanes S.A. de C.V.

Completed

Metformin Glycinate on Metabolic Control and Inflammatory Mediators in Type 2 Diabetes (COMET)

Type 2 Diabetes

Mexico
Milton S. Hershey Medical Center

Terminated

Metformin for the Treatment of Premature Pubarche in Girls

Premature Pubarche

United States
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
University of Texas Southwestern Medical Center

Completed

Type 2 Diabetes and Ambulatory Surgery Patients (Diabetes)

Diabetes Type 2
NuSirt Biopharma

Completed

Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

United States
Abide Therapeutics

Completed

Central Pain Study for ABX-1431

Multiple Sclerosis | Neuromyelitis Optica Spectrum Disorder | Transverse Myelitis | Longitudinally Extensive Transverse Myelitis

United Kingdom
Loyola University

Completed

CATHETER ANALGESIA TRIAL Phenazopyrdine vs. Placebo: a Randomized Controlled Trial (CATH)

Catheter-related Bladder Discomfort

United States
Elcelyx Therapeutics, Inc.

Completed

Assessing the PK and Effect on Glucose and GI Hormone Concentrations of Metformin Delayed-Release in Subjects With T2DM

Type 2 Diabetes Mellitus

United States
Centre Hospitalier Sud Francilien

Recruiting

Real-world Use of Hybrid Closed Loop in Adolescents and Young Adults 15-25 Years of Age With Type 1 Diabetes (BFHado)

Type1 Diabetes | Adolescents | Young Adults

France
Cortexyme Inc.

Completed

A Multiple Ascending Dose Study of COR388

Alzheimer Disease

United States
Dendreon

Completed

Dose Escalation Study of EC D-3263 HCl in Advanced Solid Tumors

Solid Tumors

United States
Brian Zuckerbraun

Completed

Effects of Metformin in a Non-Diabetic Patient Population

Inflammatory Response

United States
GlaxoSmithKline

Terminated

An Open Study to Evaluate Whether Pack Size Affects Compliance of Metformin Treatment in Subjects With Type II Diabetes

Diabetes Mellitus, Type 2

Argentina
Dong-A Pharmaceutical Co., Ltd.

Completed

Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of DA-1229 and Metformin After Oral Administration in Healthy Male Subjects

Type 2 Diabetes Mellitus

Korea, Republic of
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
Shanghai Yinnuo Pharmaceutical Technology Co.,...

Active, not recruiting

A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment

Type2 Diabetes

China
Stealth BioTherapeutics Inc.

Recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration

United States
Amicus Therapeutics

Approved for marketing

Physician Initiated Expanded Access Request for Migalastat in Individual Patients With Fabry Disease

Fabry Disease

United States, Australia
Artax Biopharma Inc
Simbec Research; ORION Clinical Services; Packaging Coordinators Inc; Centro de...

Completed

Safety Study of Immune System Modulator for Autoimmune Diseases

Healthy Volunteers

United Kingdom
Helsinn Therapeutics (U.S.), Inc

Completed

Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.

Cancer Cachexia

United States
AstraZeneca
Bristol-Myers Squibb

Completed

An 18 Week Efficacy and Safety Study of Saxagliptin and Metformin XR Combination in Subjects With Type 2 Diabetes (SCORE)

Type 2 Diabetes

United States, Peru, Mexico, Colombia, Costa Rica
Celltrion

Completed

A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 12.5 mg and MET XR 500 mg) in Healthy Volunteers

Healthy

Korea, Republic of
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin

Diabetes Mellitus, Type 2

China
Daewoong Pharmaceutical Co. LTD.

Completed

Study to Evaluate Drug-Drug Interaction of DWP16001 in Combination With Metformin in Healthy Male Adults (Phase 1 Study)

Healthy

Korea, Republic of
Haisco Pharmaceutical Group Co., Ltd.
The Fourth Hospital of Hebei Medical University

Recruiting

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK16149 Capsules and Metformin Hydrochloride Tablets

Diabetic Neuropathies | Diabetic Neuropathy Peripheral

China
Jing-yuan Fang, MD, Ph. D

Recruiting

Metformin for the Prevention of CRA Recurrence

Colorectal Adenoma | Metformin | Chemoprevention

China
Matthew Neal MD
Berry Consultants; University of Pittsburgh Medical Center

Completed

REMAP Trial for Optimizing Surgical Outcomes at UPMC (UPMCREMAP)

Aging

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

Pancreatic Adenocarcinoma | Unresectable Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7

United States
AstraZeneca

Completed

Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects

Type 2 Diabetes Mellitus

United States
ActivX Biosciences, Inc.
Kyorin Pharmaceutical Co.,Ltd

Completed

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of KRP-104 in Patients With Type 2 Diabetes Inadequately Controlled on Metformin Alone

Type 2 Diabetes

United States
Atacama Therapeutics

Completed

Exploratory Study to Assess the Efficacy and Safety of TC-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Palmar Hyperhidrosis

United States
Dalim BioTech Co., Ltd.

Completed

A Pharmacokinetic Study to Compare Co-administration of Repaglinide and Metformin HCl to Administration of Combination Preparation of Those Two Components

Diabetes Mellitus, Type 2

Korea, Republic of
Meir Medical Center
Clalit Health Services

Unknown

A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin

Diabetes Type 2

Israel
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

Type 2 Diabetes (Adult Onset)

United States
Boehringer Ingelheim

Completed

DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)

Healthy

Germany
Laboratorios Silanes S.A. de C.V.

Suspended

Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes (COMETII)

Type 2 Diabetes

Mexico
Merck KGaA, Darmstadt, Germany

Completed

Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes (CONSENT)

Diabetes Mellitus, Type 2

Germany

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