Search clinical trials for: Placebo for Saxagliptin

Total 69654 results

The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy (TSH)

Pregnancy | Subclinical Hypothyroidism | Hypothyroxinemia

United States
Eisai Inc.

Completed

Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02)

Alzheimer's Disease

United States
Sanofi

Completed

Proof of Biological Activity of SAR100842 in Systemic Sclerosis

Systemic Sclerosis

Italy, United States, France, Switzerland, United Kingdom
Sanofi

Terminated

A Clinical Trial to Assess the Clinical Benefit of SSR411298 as Adjunctive Treatment for Persistent Cancer Pain (ACT11705)

Pain | Breakthrough Cancer Pain

United States
AstraZeneca

Completed

Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg

Type 2 Diabetes

United States, Argentina, Mexico, Israel
Beijing Inno Medicine Co., Ltd.

Recruiting

A First-in-human Study of YN001 in Healthy Volunteers

Cardiovascular Diseases

Australia
Pfizer

Active, not recruiting

Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15 (PROACC-1)

Fatigue | Colorectal Cancer | Pancreatic Cancer | Cachexia | Non-small Cell Lung Cancer | Loss of Appetite

China, United States, Canada, Hungary, Australia, Slovakia, Japan, Taiwan, Bulgaria, Poland, Spain, Czechia
AstraZeneca

Completed

AZD3241 PET MSA Trial, Phase 2, Randomized,12 Week Safety and Tolerability Trial With PET in MSA Patients

Multiple System Atrophy, MSA

United States, Finland, Austria, France, Sweden, United Kingdom, Italy
Syneos Health
Shanghai Novamab Biopharmaceuticals Co. Ltd.

Terminated

First-In-Human Study to Evaluate the Safety, Tolerability, Immunogenicity, and Pharmacokinetics of LQ036

Asthma

Australia
Evofem Inc.
Neothetics, Inc

Terminated

Extension Study to Evaluate the Post-Treatment Safety and Duration of Clinical Effect of LIPO-202

Central Abdominal Bulging
Materia Medica Holding

Completed

Efficacy and Safety Clinical Trial of Tenoten for Children Liquid Dosage Form Therapy in Infants With Sequelae of Perinatal Brain Injury

Sequelae of Perinatal Brain Injury

Russian Federation
University of Arkansas

Terminated

Glutamine for the Prevention of Radiation Toxicity in Subjects Conserving Therapy

Breast Cancer

United States
Merck Sharp & Dohme LLC

Completed

A Method to Evaluate Glucose-Dependent Insulin Secretion in Healthy Males (MK-0431-179)

Type 2 Diabetes Mellitus
Nick Giannoukakis, PhD
University of South Florida; AstraZeneca; University of Pittsburgh; National Institutes...

Completed

Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes

Type 2 Diabetes Mellitus | Insulin Resistance

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)

Type 2 Diabetes Mellitus
Frontier Biotechnologies Inc.

Recruiting

Evaluate the Efficacy and Safety of FB2001 for Inhalation in Patients With Mild to Moderate COVID-19

Mild to Moderate COVID-19

China
AlgiPharma AS
Imperial College London; Cystic Fibrosis Foundation; University Hospital of Cologne and other collaborators

Withdrawn

A Dose-finding Study of Inhaled OligoG vs Placebo in Patients With Cystic Fibrosis (SMR3372)

Cystic Fibrosis

Germany
Kyowa Kirin Co., Ltd.

Completed

A Clinical Pharmacology Study of Saxagliptin in Patients With Type 2 Diabetes Mellitus

Diabetes

Japan
Aro Biotherapeutics

Recruiting

Study to Assess the Safety, Tolerability, PK and PD of ABX1100

Healthy

Canada
Hoffmann-La Roche

Completed

A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin.

Diabetes Mellitus Type 2

United States, France, Switzerland, Germany, South Africa, Korea, Republic of, Puerto Rico, Canada, Taiwan, Spain, Poland, Slovakia, Thailand, Mexico, Turkey, Australia, Greece, Norway, Sweden, Peru, Romania, Argentina, United Kingdom
Merck Sharp & Dohme LLC

Completed

Clinical Study on Sitagliptin for Assessment of Glucose-lowering Effects (0431-045)

Diabetes Mellitus, Non-Insulin-Dependent
Xuanzhu Biopharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Trial of XZP-5610 Tablets in Healthy Subjects

Nonalcoholic Steatohepatitis (NASH)

China
Merck Sharp & Dohme LLC

Completed

A Study of Different Doses of Sitagliptin (MK-0431) in Participants With Type 2 Diabetes Mellitus (MK-0431-014)

Type II Diabetes Mellitus
AstraZeneca

Completed

Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR

Diabetes Mellitus

United States
AstraZeneca

Completed

Bioequivalence Study of Fixed Dose Combination of 2.5 mg Saxagliptin/850 mg Metformin Tablet Relative to 2.5 mg Onglyza and 850 mg Glucophage Tablets Co-Administered

Type 2 Diabetes Mellitus

United States
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Completed

Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients

Primary Sjögren's Syndrome

United States, France, United Kingdom, Australia, Germany, Hungary, Spain
Merck Sharp & Dohme LLC

Completed

Study of the Bioequivalence of Two Tablet Forms of MK0431 (0431-027)

Type 2 Diabetes Mellitus
Gilead Sciences

Active, not recruiting

Study of HBV Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis B

Chronic Hepatitis B

Taiwan, New Zealand
University at Buffalo

Withdrawn

Sitagliptin in Type I Diabetic Patients

Diabetes Type I

United States
Novartis Pharmaceuticals

Active, not recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol. (V-Mono China)

Primary Hypercholesterolemia or Mixed Dyslipidemia

China
Chinese Academy of Medical Sciences, Fuwai Hospital
Tianjin Tasly Pharmaceutical Co., Ltd

Unknown

The Study of Qishenyiqi Drop Pills in Improving the Prognosis of Heart Failure Patients

Heart Failure

China
Ambrosia - SupHerb Ltd.

Unknown

Comparative Efficacy and Tolerability of No7 in Osteoarthritis of the Knee

Osteoarthritis, Knee
Merck Sharp & Dohme LLC
Pfizer

Completed

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Type 2 Diabetes Mellitus
AstraZeneca

Completed

Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone

Diabetes Mellitus, Type 2

United States, Chile, Argentina, Brazil, Canada, Mexico, Puerto Rico, Taiwan, Australia
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Addition of Sitagliptin to Metformin Compared With the Addition of Dapagliflozin to Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) and Mild Renal Impairment Who Have Inadequate Glycemic Control on Metformin With or Without a Sulfonylurea (MK-0431-838)

Type 2 Diabetes Mellitus
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Peanut Oral Immunotherapy in Children (IMPACT)

Peanut Hypersensitivity

United States
Zafgen, Inc.

Terminated

An Efficacy and Safety Study of Beloranib in Obese Subjects With Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes

Australia
AbbVie

Not yet recruiting

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Migraine
AbbVie

Recruiting

Study of Oral Atogepant Tablets to Assess Change in Disease Activity in Adult Japanese Participants With Episodic Migraine (Release)

Migraine

Japan
GeneScience Pharmaceuticals Co., Ltd.
Peking Union Medical College Hospital

Unknown

Clinical Study of Genakumab for Injection in Chinese Healthy Volunteers

Juvenile Idiopathic Arthritis

China
Vigonvita Life Sciences

Recruiting

A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV

Respiratory Syncytial Virus Infection

China
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
The University of Texas Medical Branch, Galveston

Terminated

Panhematin for Prevention of Acute Attacks of Porphyria

Hereditary Coproporphyria | Acute Intermittent Porphyria | Variegate Porphyria

United States
Medical University of South Carolina
National Institute of General Medical Sciences (NIGMS)

Completed

Sensory Stimulation to Enhance Hand Function Post Stroke

Stroke

United States
Guangzhou Henovcom Bioscience Co. Ltd.
Heilongjiang Zhenbaodao Pharmaceutical Co., Ltd.

Completed

A Study of HNC042 in Healthy Chinese Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics

Influenza

China
Bayside Health

Completed

A Trial of Immunological Outcomes of Sublingual Immunotherapy for House Dust Mite (D. Pteronyssinus) Allergy

Asthma | Allergic Rhinitis

Australia
KAI Pharmaceuticals

Completed

Safety of KAI-9803 for Injection With Angioplasty Following Heart Attack

Myocardial Infarction

United States
AstraZeneca

Completed

Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)

Diabetes Mellitus

United States
Shanghai Gebaide Biotechnology Co., Ltd.

Unknown

A Phase III Trial of Recombinant Human Apo-2 Ligand for Injection

Non-small-cell Lung Cancer (NSCLC) Stage IV

China
Sabyasachi Sen

Terminated

Effect of Saxagliptin and Dapagliflozin on Endothelial Progenitor Cell in Patients With Type 2 Diabetes Mellitus

Cardiovascular Diseases | Diabetes Mellitus, Type 2

United States

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