Clinical Trials Sponsored by Hoxworth Blood Center

Total 1208 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Withdrawn

HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection

Stage III Adult Hodgkin Lymphoma | Stage IV Adult Hodgkin Lymphoma | Human Immunodeficiency Virus 1 Positive | Stage I Adult Hodgkin Lymphoma | Stage II Adult Hodgkin Lymphoma | Stage I Adult Non-Hodgkin Lymphoma | Stage II Adult Non-Hodgkin Lymphoma | Stage III Adult Non-Hodgkin Lymphoma | Stage IV...

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Diffuse Large B-Cell Lymphoma | Refractory Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Plasma Cell Myeloma | Refractory Chronic Lymphocytic Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Chronic Phase Chronic Myelogenous... and other conditions

United States, Germany, Italy
Sunnybrook Health Sciences Centre
Canadian Blood Services; National Blood Foundation; Canadian Department of National...

Completed

The Trauma- Formula-Driven Versus Lab-Guided Study (TRFL Study) (TRFL)

Hemorrhagic Shock | Trauma Coagulopathy

Canada
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

STEP Together: An Effectiveness-Implementation Study of Social Incentives and Physical Activity

Physical Activity

United States
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI); Genentech, Inc.

Completed

Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure (GRAIL)

Respiratory Failure | Acute Respiratory Distress Syndrome | Acute Lung Injury

United States
University Medical Centre Ljubljana
Stanford University; Blood Transfusion Centre of Slovenia

Completed

Safety and Efficacy Study of Stem Cell Transplantation to Treat Dilated Cardiomyopathy

Dilated Cardiomyopathy

Slovenia
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI); National Institute of Allergy and Infectious... and other collaborators

Recruiting

Safety Study of Cord Blood Units for Stem Cell Transplants

Lymphoma | Leukemia | Aplastic Anemia | Myelodysplastic Syndrome (MDS)

United States
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI); Rocket Pharma Limited

Terminated

Gene Therapy for Fanconi Anemia

Fanconi Anemia

United States
bluebird bio
Center for International Blood and Marrow Transplant Research

Recruiting

A Study of Participants With β-Thalassemia Treated With Betibeglogene Autotemcel

Beta-Thalassemia

United States
Boston Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Haiti Community Health Workers (CHW) Adaptation

Heart Failure

Haiti
Boston Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sickle Cell Anemia WE CARE (SCAWECARE)

Sickle Cell Disease

United States
Boston Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Educational and Supportive Interventions to Prevent Cardiopulmonary Rehospitalization

Heart Diseases | Cardiovascular Diseases

United States
Baystate Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Influence of CPB Temperature on CABG Morbidity

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Neurologic Manifestations
Tufts Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Epidemiology of Carotid IMT Progression in MESA - Ancillary Study

Heart Diseases | Cardiovascular Diseases | Atherosclerosis | Carotid Artery Diseases | Coronary Arteriosclerosis
Sanquin Research & Blood Bank Divisions
Atrium Medical Center; Maasland Hospital

Completed

Collection of Autologous Blood Products by Double Erythrocytapheresis

Pre Operative Autologous Donation

Netherlands
Washington University School of Medicine
McDonnell Center; Paula and Roger Riney Blood Cancer Research

Terminated

Serum Neurofilament Light (NfL) as a Marker for Brain Injury in Individuals Undergoing Chimeric Antigen Receptor-modified T Therapy

Neurotoxicity

United States
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI); University of Washington

Completed

Diet and Systemic Inflammation (DASI)

Obesity | Cardiovascular Disease | Type 2 Diabetes Mellitus | Intestinal Permeability | Low-grade Chronic Inflammation

United States
Montefiore Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination (PRAGMATIC)

Asthma Childhood

United States
Max O'Donnell
New York Blood Center; Amazon.com, Inc.

Completed

Plasma Therapy of COVID-19 in Severely Ill Patients

SARS-CoV-2 Infection

United States, Brazil
Tufts Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Heart Muscle Viability and Remodeling in Individuals Post-Heart Attack

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Heart Failure, Congestive

United States
Tufts Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium. (IMMEDIATE)

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Angina, Unstable | Heart Failure, Congestive

United States
Tufts Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Progression of Sub-Clinical Atherosclerosis

Heart Diseases | Cardiovascular Diseases | Atherosclerosis | Carotid Artery Diseases
National Heart Institute, Mexico
National Center of Blood Transfusion Mexico.

Unknown

Intracoronary Autologous Stem Cell Transplantation in ST Elevation Myocardial Infarction: TRACIA STUDY. (TRACIA)

Acute Myocardial Infarction

Mexico
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Congenital Amegakaryocytic Thrombocytopenia | Paroxysmal Nocturnal Hemoglobinuria | Shwachman-Diamond Syndrome | Bone Marrow Failure Syndrome | Congenital Pure Red Cell Aplasia | Hereditary Sideroblastic Anemia | Hematologic Neoplasm With Germline GATA2 Mutation | Hematologic Neoplasm With Germline... and other conditions

United States
Centro Nazionale Sangue
Italian National Cord Blood Network

Completed

Clinical Efficacy of Platelet Gel From Cord Blood for the Treatment of Diabetic Foot Ulcers (CBPG-DFU)

Diabetic Foot Ulcers

Italy, Spain
Memorial Sloan Kettering Cancer Center
Sanofi; Duke University; Weill Medical College of Cornell University; New York...

Active, not recruiting

Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease

Sickle Cell Disease

United States
bluebird bio
Center for International Blood and Marrow Transplant Research

Recruiting

A Study of Participants With Cerebral Adrenoleukodystrophy (CALD) Treated With Elivaldogene Autotemcel (Stargazer)

Cerebral Adrenoleukodystrophy (CALD)

United States
Boston Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Prehospital Telemedicine Feasibility/Acceptability Pilot

Respiratory Distress Syndrome

United States
Tufts Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure (ASTRID-HF)

Heart Failure | Muscle Atrophy

United States
Montefiore Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Use of a Probiotic Supplement to Prevent Asthma in Infants

Asthma

United States
Weill Medical College of Cornell University
New York Blood Center

Terminated

IPA Targeted Adoptive Immunotherapy vs Adult Haplo-identical Cell Infusion During Induction of High Risk Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
Center for Blood and Tissues IV and V Region, Chile

Unknown

Reduce Stress Associated With Needle Aspiration, in Voluntary and Replacement Blood Donors

Stress

Chile
Kuakini Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Family Blood Pressure Program - SAPPHIRe Network

Heart Diseases | Cardiovascular Diseases | Hypertension
Boston Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Clinician Counseling and Cultural Competency to Improve Hypertension Control and Therapy Adherence (HCTA)

Heart Diseases | Cardiovascular Diseases | Hypertension

United States
Sanquin Research & Blood Bank Divisions
Radboud University Medical Center; Maastricht University Medical Center; Atrium...

Completed

Haemochromatosis:Phlebotomy Versus Erythrocytapheresis Therapy

Hemochromatosis

Netherlands
Center for International Blood and Marrow Transplant...
National Marrow Donor Program; Pediatric Blood and Marrow Transplant Consortium

Active, not recruiting

Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies

Juvenile Myelomonocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myelodysplasia | Acute Lymphoblastic Leukemia/Lymphoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Non-Neoplastic Hematologic and Lymphocytic Disorder

United States
Centers for Disease Control and Prevention
New York Blood Center; The New York Academy of Medicine

Completed

A Behavioral Intervention to Reduce Sexual Risk Among African-American Men Who Have Sex With Men

HIV Infections

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

MOdification Of THe Early-Life Respiratory Microbiome Through Vaginal SEEDing (MOTHER SEED)

Cesarean Section | Microbiome | Vaginal Seeding | Nose

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

CPAP for the Treatment of Supine Hypertension

Parkinson Disease | Multiple System Atrophy | Neurogenic Orthostatic Hypotension | Pure Autonomic Failure | Supine Hypertension | Autonomic Failure

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)

Idiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Splanchnic Venous Capacitance in Postural Tachycardia Syndrome

Postural Tachycardia Syndrome (POTS)

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

Parkinson Disease | Multiple System Atrophy | Neurogenic Orthostatic Hypotension | Pure Autonomic Failure | Autonomic Failure

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Autonomic Determinants of POTS - Pilot1

Postural Tachycardia Syndrome

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Automated Abdominal Binder for Orthostatic Hypotension

Multiple System Atrophy | Orthostatic Hypotension | Pure Autonomic Failure | Autonomic Failure

United States
Ossium Health, Inc.
Center for International Blood and Marrow Transplant Research

Withdrawn

Cryopreserved MMUD BM With PTCy for Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Leukemia | Acute Lymphocytic Leukemia | T-lymphoblastic Lymphoma | Acute Undifferentiated Leukemia | Acute Biphenotypic Leukemia
Cedars-Sinai Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Reproductive Hormones And Pre-Clinical Cardiovascular Disease (CVD) In Women

Heart Disease

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving Prematurity-Related Respiratory Outcomes at Vanderbilt (IMPROV)

Preterm Birth | Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity

United States
Rush University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sleep Length and Circadian Regulation in Humans (HAM)

Sleep Disorders

United States

Clinical Trials Sponsored by Hoxworth Blood Center

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