Clinical Trials Sponsored by Insmed Incorporated

Total 1682 results

Proacta, Incorporated

Completed

PR104 and G-CSF in Treating Patients With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States, New Zealand
Proacta, Incorporated

Completed

A Phase I Dose Escalation Trial of PR104 Given Weekly in Subjects With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

New Zealand
Proacta, Incorporated

Completed

PR-104 and Docetaxel or Gemcitabine in Treating Patients With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

New Zealand, United States
Biosynexus Incorporated

Completed

Safety and Pharmacokinetics Study in Adults for the Prevention of S. Epidermidis Infection in Low Birth Weight Infants

Staphylococcal Sepsis

United States
Genta Incorporated

Completed

Phase II Gallium Nitrate in Relapsed or Refractory Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma | Refractory Lymphoma | Relapsed Lymphoma | Low-Grade Lymphoma | Intermediate-Grade Lymphoma

United States
Lenstec Incorporated

Completed

Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens

Presbyopia | Cataracts

United States
Celularity Incorporated

Active, not recruiting

CYNK-101 in Combination With Trastuzumab and Pembrolizumab in Patients With Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma

Metastatic HER2 Positive Gastroesophageal Junction Cancer

United States
GlycoMimetics Incorporated

Terminated

Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Vaso-occlusive Crisis | Pain Crisis | Sickle Cell Disorders

United States, Canada
VertiFlex, Incorporated

Completed

The STEPS - Totalis™ Trial

Lumbar Spinal Stenosis

United States
Celularity Incorporated

Completed

A Safety Study of Human Cord Blood Derived, Culture-expanded, Natural Killer Cell (PNK-007) Infusion With or Without Subcutaneous Recombinant Human Interleukin-2 (rhIL-2) Following Autologous Stem Cell Transplant for Multiple Myeloma (MM)

Multiple Myeloma

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of Age on the Pharmacokinetics, Safety and Tolerability of IV Rivipansel.

Healthy

United States
GlycoMimetics Incorporated

Completed

Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease

Sickle Cell Disease

United States
VertiFlex, Incorporated

Withdrawn

Assessing Superion Clinical Endpoints vs. Decompression (ASCEND)

Spinal Stenosis, Lumbar Region With Neurogenic Claudication

United States
GlycoMimetics Incorporated

Completed

Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy in AML

Leukemia, Myeloid, Acute

United States, Ireland, Australia
Hollister Incorporated

Completed

The Advocate Study

Ostomy

United States, Canada
Celularity Incorporated

Completed

A Randomized, Double-Blind, Placebo-Controlled Dose-Escalation Study to Determine the Safety and Efficacy of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Crohn's Disease

Crohns Disease

United States
Celularity Incorporated

Terminated

Safety of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults With Stage II or III Pulmonary Sarcoidosis

Stage 2 Pulmonary Sarcoidosis | Stage 3 Pulmonary Sarcoidosis

United States
Hollister Incorporated

Completed

Wound Fluid Protease Levels During Use of Novel Wound Dressing

Venous Stasis Ulcers

United States
Ingredion Incorporated

Completed

Effects of Dietary Fiber on Gastrointestinal Function

Gastrointestinal Health

United States
Ingredion Incorporated

Completed

Effects of a Dietary Fiber on Fecal Microbiota and Metabolism

Focus of the Study is on Gut Health

United States
Proacta, Incorporated

Terminated

Randomized Phase 1/2 Open-Label Trial of PR104 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

United States, Taiwan, Singapore, Hong Kong
Cebix Incorporated

Completed

Safety and Pharmacokinetics of CBX129801 in Patients With Type 1 Diabetes

Diabetes Mellitus | Type 1 Diabetes | Peripheral Diabetic Neuropathy

United States
Proacta, Incorporated

Terminated

PR104 in Treating Patients With Previously Untreated or Relapsed Small Cell Lung Cancer

Lung Cancer

United States
Proacta, Incorporated

Unknown

PR104 in Treating Patients With Refractory/Relapsed Acute Leukemia

Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
Genta Incorporated

Unknown

Tesetaxel as First-line Therapy for Metastatic Breast Cancer

Breast Neoplasm

United States
Genta Incorporated

Unknown

Study of Tesetaxel in Japanese Patients With Solid Tumors

Advanced Solid Tumors

Japan
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Hollister Incorporated

Completed

Preliminary Evaluation of CASTLE Barrier North American Prototype

Peristomal Skin Complication

United States, Canada
Genta Incorporated

Unknown

Tesetaxel as Second-line Therapy for Patients With Advanced Melanoma and Normal Serum LDH

Melanoma

United States
Genta Incorporated

Completed

Genasense® (Oblimersen Sodium), Fludarabine, and Rituximab in Subjects With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
Genta Incorporated

Completed

Trial of Dacarbazine With or Without Genasense in Advanced Melanoma (AGENDA)

Melanoma

United States, France, United Kingdom, Spain, Switzerland, Australia, Canada, Germany, Poland, Italy, Austria, Czech Republic
LensAR Incorporated

Unknown

Laser Treatment of the Crystalline Lens

Cataract

Mexico
LensAR Incorporated

Unknown

Prospective Clinical Trial of the LensAR Laser System

Cataract

Mexico
Genta Incorporated

Withdrawn

This Study is Being Performed to Evaluate the Effect of Genasense on the Efficacy and the Safety of Rituximab/Fludarabine Combination Treatment in Previously Untreated Subjects With Chronic Lymphocyctic Leukemia(CLL)

Lymphocytic Leukemia
Genta Incorporated

Completed

A Phase I Study of G3139 Subcutaneous in Solid Tumors

Tumors

United States
Chisquares Incorporated

Not yet recruiting

Collaborative Open Research Initiative Study (CORIS-1) (CORIS-1)

COVID-19 | Burnout, Professional | Patient Engagement | Artificial Intelligence | Substance Use Disorders | Mental Health Issue | Climate Change | Preventable Disease, Vaccine | Emerging Infectious Disease | Online Education
Celularity Incorporated

Recruiting

Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01)

Neoplasms | Neoplasms by Histologic Type | Hematologic Diseases | Leukemia | Leukemia, Myeloid | Leukemia, Myeloid, Acute | Hematologic Neoplasms | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Antimetabolites, Antineoplastic | Leukemia in Remission | Relapsed... and other conditions

United States
Hollister Incorporated

Recruiting

Observational Study of Ostomy Consumers (OSO)

Ostomy

United States
AtlasMedx, Incorporated

Active, not recruiting

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Homologous Recombination Deficiency | Advanced Malignant Neoplasm

United States
GlycoMimetics Incorporated

Active, not recruiting

Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Canada, Spain, Australia, Netherlands, France, Ireland, Italy, United Kingdom
Accuray Incorporated

Completed

CyberKnife Radiosurgery For Low & Intermediate Risk Prostate Cancer: Emulating HDR Brachytherapy Dosimetry

Prostatic Neoplasms | Prostate Cancer | Prostate Neoplasms | Cancer of the Prostate | Prostatic Cancer

United States
Accuray Incorporated

Completed

CyberKnife Radiosurgery for Organ-Confined Prostate Cancer: Homogenous Dose Distribution

Prostatic Neoplasms | Prostate Cancer | Prostate Neoplasms | Cancer of the Prostate | Prostatic Cancer

United States
Celularity Incorporated

Terminated

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM (CYNK001GBM01)

Glioblastoma Multiforme | Molecular Mechanisms of Pharmacological Action | Giant Cell Glioblastoma | Astrocytoma, Grade IV | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Cyclophosphamide | Immunosuppressive Agents | Immunologic Factors | Antiviral... and other conditions

United States
Hollister Incorporated

Completed

Consumer Evaluation of Intermittent Catheter Product Modifications

Urinary Incontinence

United States
GlycoMimetics Incorporated

Terminated

A Study to Determine Safety and Tolerability of GMI-1359 in Subjects With HR+ Metastatic Breast Cancer

Breast Cancer | Breast Cancer Metastatic | HR+ Metastatic Breast Cancer

United States
LensAR Incorporated

Terminated

Feasibility Study of Laser Treatment of the Crystalline Lens to Correct Presbyopia

Cataract | Presbyopia

Philippines
Celularity Incorporated

Terminated

Efficacy and Safety of Intramuscular PDA-002 in Subjects Who Have Diabetic Foot Ulcer With and Without Peripheral Arterial Disease

Diabetic Foot | Peripheral Arterial Disease

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
GlycoMimetics Incorporated

Completed

Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease

Anemia, Sickle Cell

United States, Canada
GlycoMimetics Incorporated

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Rivipansel With rHuPH20 in Healthy Subjects

Healthy

Belgium

Clinical Trials Sponsored by Insmed Incorporated

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