Clinical Trials Sponsored by LNC THERAPEUTICS

Total 45093 results

Atsena Therapeutics Inc.

Recruiting

ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis (LIGHTHOUSE)

X-linked Retinoschisis

United States
G1 Therapeutics, Inc.

Recruiting

Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan

Extensive-stage Small-cell Lung Cancer

Spain, Greece, Turkey, Poland, Georgia, Austria, Belgium, Bulgaria, Germany, Hungary
Travere Therapeutics, Inc.

Recruiting

A Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgAN (SPARTACUS)

Immunoglobulin A Nephropathy

United States, Hong Kong
LAPIX Therapeutics Inc.

Recruiting

First-in-Human Trial in Healthy Adult Volunteers to Evaluate Safety, Tolerability and PK of LAPIX Study Drug; LPX-TI641

Multiple Sclerosis | Autoimmune Diseases

United States, Jordan
ImmuneSensor Therapeutics Inc.

Recruiting

Study of PULSAR-ICI +/- IMSA101 in Patients With Oligoprogressive Solid Tumor Malignancies

Oligoprogressive

United States
Aviceda Therapeutics, Inc.

Recruiting

A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) (SIGLEC)

Macular Degeneration | Geographic Atrophy of the Macula

United States
AnHeart Therapeutics Inc.

Recruiting

IDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid Tumor

Cholangiocarcinoma With IDH1 Mutation | Solid Tumors With IDH1 Mutation

China
Marker Therapeutics, Inc.

Recruiting

Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma (APOLLO)

Non Hodgkin Lymphoma | Non-Hodgkin Lymphoma, Adult | Non-Hodgkin Lymphoma, Refractory | Non-Hodgkin Lymphoma, Relapsed

United States
Kymera Therapeutics, Inc.

Recruiting

Safety and Clinical Activity of KT-253 in Adult Patients With High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Advanced Solid Tumors | Acute Lymphocytic Leukemia | Lymphomas | Myeloid Malignancies

United States
Zucara Therapeutics Inc.

Recruiting

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes (ZONE)

Type 1 Diabetes Mellitus With Hypoglycemia

United States, Canada
Multitude Therapeutics Inc.

Recruiting

AMT-116 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Australia
Abeona Therapeutics, Inc

Recruiting

EB-101 Treatment for New and Previously Treated Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Epidermolysis Bullosa | Recessive Dystrophic Epidermolysis Bullosa | RDEB

United States
Lisata Therapeutics, Inc.

Recruiting

A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors (BOLSTER)

Cholangiocarcinoma | Bile Duct Cancer | Intrahepatic Cholangiocarcinoma | Gallbladder Carcinoma | Gallbladder Cancer | Gall Bladder Cancer | Extrahepatic Cholangiocarcinoma | Gall Bladder Carcinoma

United States, Spain
Sustained Therapeutics Inc.

Recruiting

A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain

Chronic Pain

Canada
C4 Therapeutics, Inc.

Recruiting

A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors

Melanoma | NSCLC | Solid Tumors | CRC | ATC

United States, Spain, France
Olatec Therapeutics LLC

Recruiting

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Arthritis | Joint Pain | Gout | Gout Flare | Gouty Arthritis | Acute Gout Flare | Gout Attack

United States, Spain, France
Palvella Therapeutics, Inc.

Recruiting

A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita

Pachyonychia Congenita

United States
Inhibikase Therapeutics, Inc.

Recruiting

A Dose Calibration Study Comparing IkT-001Pro to Imatinib Mesylate 400mg

CML

United States
Cyclo Therapeutics, Inc.

Recruiting

A 6-Month Study to Evaluate the Safety & Potential Efficacy of Trappsol Cyclo in Patients With Early Alzheimer's Disease (EAD501)

Alzheimer's Disease

United States
Stemline Therapeutics, Inc.

Recruiting

ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study (ELCIN)

Metastatic Breast Cancer

United States, Georgia, Brazil, Bulgaria, Romania
Oncternal Therapeutics, Inc

Recruiting

A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies

Relapsed/Refractory Aggressive B-Cell Malignancies

United States
Stemline Therapeutics, Inc.

Recruiting

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer (ELEVATE)

Breast Cancer | Metastatic Breast Cancer

United States
Minneamrita Therapeutics LLC

Recruiting

Minnelide Along With Abraxane Plus Gemcitabine in Patients With Metastatic Adenocarcinoma of the Pancreas

Metastatic Adenocarcinoma of the Pancreas

Korea, Republic of
Edgewise Therapeutics, Inc.

Recruiting

A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX) (LYNX)

Duchenne Muscular Dystrophy

United States
Soleno Therapeutics, Inc.

Not yet recruiting

An Open-Label Study of Diazoxide Choline in Patients With Genetic Obesities

SH2B1 Deficiency Obesity | Obesity Associated With PCSK1 Mutation (rs6232 Variant) | SIM1 Deficiency Obesity
SPR Therapeutics, Inc.

Recruiting

The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

Cervicogenic Headache | Occipital Neuralgia

United States
MindImmune Therapeutics, Inc.

Recruiting

Exploratory Open Label Study for Development of a Method To Detect Dendritic Cells

Probable Alzheimer's Disease

United States
Leap Therapeutics, Inc.

Recruiting

Phase 2 Study of DKN-01 in Colorectal Cancer (DeFianCe)

Colorectal Cancer | Colorectal Cancer Metastatic | Colo-rectal Cancer | Colorectal Adenocarcinoma

United States, Korea, Republic of, Germany
Onconic Therapeutics Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of JPI-547 in Platinum-resistant, Advanced/Relapsed Ovarian Cancer Subjects Previously Treated With a PARP Inhibitor

Ovarian Cancer
Beam Therapeutics Inc.

Recruiting

BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease (BEACON)

Sickle Cell Disease

United States
Cloudbreak Therapeutics, LLC

Recruiting

A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium

Pterygium

United States, China, India, Australia, New Zealand
Onconic Therapeutics Inc.

Recruiting

JP-1366 20mg Versus Esomeprazole 40mg in Patients With Erosive Esophagitis

Erosive Esophagitis

Korea, Republic of
Cerevel Therapeutics, LLC

Recruiting

A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia

Schizophrenia

United States, Bulgaria, Hungary, Puerto Rico
Impact Therapeutics, Inc.

Not yet recruiting

An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fed Condition

Solid Tumor
Ashvattha Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (AMD) or Subjects With Diabetic Macular Edema (DME) (Tejas)

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Denali Therapeutics Inc.

Recruiting

A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II) (COMPASS)

Mucopolysaccharidosis II

United States, Spain, United Kingdom, Czechia, France, Canada, Italy, Belgium, Netherlands, Germany, Argentina, Sweden, Turkey, Colombia
Sorrento Therapeutics, Inc.

Not yet recruiting

Study to Assess the Safety and Preliminary Efficacy of STI-1386 Oncolytic Virus in Relapsed or Refractory Solid Tumors

Sarcoma | Cancer | Solid Tumor | Cancer of Pancreas | Hepatic Metastasis
Century Therapeutics, Inc.

Recruiting

A Study of CNTY-101 in Participants With CD19-Positive B-Cell Malignancies (ELiPSE-1)

Aggressive Non-Hodgkin Lymphoma | R/R CD19-Positive B-Cell Malignancies | Indolent Non-Hodgkin Lymphoma

United States
BiOneCure Therapeutics Inc.

Recruiting

A Study in Patients With Advanced Cancers

Cancer | Advanced Solid Tumor | Advanced Cancer | Oncology

United States
Jubilant Therapeutics Inc.

Recruiting

A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
Panbela Therapeutics, Inc.

Recruiting

Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer (ASPIRE)

Pancreatic Cancer Metastatic | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Stage IV

United States, Belgium, Germany, Spain, Korea, Republic of, Australia, France, Italy, Austria, United Kingdom
Treadwell Therapeutics, Inc

Recruiting

CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer

Breast Cancer | Advanced Solid Tumor

United States
Poseida Therapeutics, Inc.

Recruiting

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors

Renal Cell Carcinoma | Breast Cancer | Nasopharyngeal Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States
TScan Therapeutics, Inc.

Recruiting

A Tissue Collection Study in Patients Who Respond to Immune Checkpoint Inhibitors to Identify Targets of Tumor-Reactive T Cells.

Solid Tumor, Adult

United States
Cerevel Therapeutics, LLC

Recruiting

A Trial of 15 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia

Schizophrenia

United States, Bulgaria, Hungary
Thiogenesis Therapeutics, Inc.

Not yet recruiting

Study of Cysteamine-pantetheine Disulfide (TTI-0102) in Mild to Moderate COVID-19

COVID-19 | COVID-19 Acute Respiratory Distress Syndrome
Viking Therapeutics, Inc.

Recruiting

Phase 1 Study to Evaluate the Safety and Tolerability of VK2735

Weight Loss | NASH

Australia
Viracta Therapeutics, Inc.

Recruiting

Nanatinostat Plus Valganciclovir in Patients With Advanced EBV+ Solid Tumors, and in Combination With Pembrolizumab in EBV+ RM-NPC

Nasopharyngeal Carcinoma | EBV-Related Gastric Carcinoma | EBV-Related Leiomyosarcoma | EBV Related Carcinoma | EBV-Related Sarcoma

United States, Hong Kong, Taiwan, Korea, Republic of, Singapore, Australia, Canada, Malaysia
Rapa Therapeutics LLC

Recruiting

RAPA-201 Therapy of Solid Tumors

Breast Cancer | Head and Neck Cancer | Gastric Cancer | Solid Tumor | Bladder Cancer | Triple Negative Breast Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Malignant Melanoma | Carcinoma of Unknown Primary | Squamous Cell Carcinoma of Larynx | Squamous Cell Carcinoma of Oral Cavity | Squamous Cell Carcinoma of Nasopharynx and other conditions

United States
Nurix Therapeutics, Inc.

Recruiting

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Mantle Cell Lymphoma (MCL) | Follicular Lymphoma (FL) | Primary Central Nervous System Lymphoma (PCNSL) | Marginal Zone Lymphoma (MZL) | Waldenstrom Macroglobulinemia (WM) | Diffuse Large B Cell Lymphoma (DLBCL)

United States, United Kingdom, Netherlands

Clinical Trials Sponsored by LNC THERAPEUTICS

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