Clinical Trials Sponsored by University Hospital Birmingham, NHS Foundation Trust, Hospital, Birmingham, UK

Total 1501 results

University of Manchester
King's College Hospital NHS Trust; Cardiff University; University College London... and other collaborators

Not yet recruiting

Immune Profiles in Myasthenia Gravis

Myasthenia Gravis
Cambridge University Hospitals NHS Foundation Trust
Rigshospitalet, Denmark; Birmingham Women's and Children's NHS Foundation Trust and other collaborators

Unknown

Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children

Small for Gestational Age
Robert Jones and Agnes Hunt Orthopaedic and District...
University Hospital Birmingham NHS Foundation Trust

Recruiting

A Review of the Management and Outcomes of Children With SMA in the West Midlands During 2017-2022

Spinal Muscular Atrophy

United Kingdom
Obafemi Awolowo University Teaching Hospital
University Hospital Birmingham NHS Foundation Trust; Cures Within Reach

Completed

Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) (ATORTUB)

Tuberculosis | Tuberculosis, Pulmonary

United Kingdom, Nigeria
University of Birmingham
Dalhousie University; NORTHAMPTONSHIRE HEALTHCARE NHS FOUNDATION TRUST

Unknown

Computerised Working Memory Training in Acquired Brain Injury

Acquired Brain Injury
University Hospital Southampton NHS Foundation...
Cancer Research UK; The Christie NHS Foundation Trust; Celldex Therapeutics; Oxford... and other collaborators

Active, not recruiting

A Combination of Rituximab and Varlilumab Immunotherapy in Patients With B-cell Lymphoma (RiVa)

B Cell Lymphoma

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Guy's and St Thomas' NHS Foundation Trust; University Hospital Birmingham NHS... and other collaborators

Withdrawn

Reduction in Arrhythmia Burden With Left Atrial Posterior Wall Ablation for Persistent AF (RABLAP-AF)

Atrial Fibrillation

United Kingdom
Royal Free Hospital NHS Foundation Trust
Innovate UK

Active, not recruiting

CirrhoCare in COVID-19: A Pilot, Remote, Home Monitoring Study in Advanced Cirrhosis

Decompensated Cirrhosis

United Kingdom
University of Surrey
The Leeds Teaching Hospitals NHS Trust; University Hospital Birmingham NHS... and other collaborators

Recruiting

The National Transition Evaluation Study (NTES)

Young People With All Long-term Health Conditions

United Kingdom
Papworth Hospital NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

Validation of UK Protocols to Exclude Brain Blood Flow During Normothermic Regional Perfusion (NRP)

Cerebral Blood Flow
Imperial College Healthcare NHS Trust
Barts & The London NHS Trust; Royal Free Hospital NHS Foundation Trust; University... and other collaborators

Active, not recruiting

TB PCR in BAL and EBUS-TBNA (TRiBE)

Tuberculosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Diabetes UK

Completed

Study of CBME in the Relief of Painful Diabetic Neuropathy

Diabetic Neuropathy | Painful

United Kingdom
University Hospital Southampton NHS Foundation...
Sheffield Teaching Hospitals NHS Foundation Trust; University Hospitals, Leicester and other collaborators

Completed

CPET and Outcome After Oesophagogastric Cancer Surgery

Upper Gastrointestinal Disorders

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; Birmingham Women's and Children's... and other collaborators

Unknown

Evaluation of the High Frequency Digit Triplet Test in Cystic Fibrosis (3D-CF)

Cystic Fibrosis | Sensorineural Hearing Loss

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Portsmouth... and other collaborators

Unknown

The Wessex Fit-4-Cancer Surgery Trial (WesFit)

Cancer

United Kingdom
University of Birmingham
University Hospitals of North Midlands NHS Trust

Active, not recruiting

Predict&Prevent: Use of a Personalised Early Warning Decision Support System to Predict and Prevent Acute Exacerbations of COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
ReiThera Srl
University of Oxford; Oxford University Hospitals NHS Trust; University Hospital...

Completed

Study of a New MVA Vaccine for Hepatitis C Virus

Hepatitis C Infection

United Kingdom
Jerry Marsden
Department of Health, United Kingdom

Completed

Effect of Topical Imiquimod on Lentigo Maligna (LIMIT-1)

Lentigo Maligna

United Kingdom
Liverpool University Hospitals NHS Foundation Trust
University Hospital Southampton NHS Foundation Trust

Completed

The Effect of Chemotherapy and Surgery for Cancer on Exercise Capacity

Tumor of Esophagus, Stomach and Duodenum

United Kingdom
Peripal AG
University Hospital Birmingham NHS Foundation Trust; Swiss Federal Institute...

Completed

Human Factors Validation Testing for the Peripal System; a Manual Connection Assist Device for Peritoneal Dialysis Devices

Renal Failure | Peritoneal Dialysis | Renal Replacement Therapy | End Stage Renal Failure on Dialysis | End Stage Renal Disease on Dialysis

United Kingdom
University Hospital Birmingham NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Cytomegalovirus Control in Critical Care (CCCC)

Critical Illness

United Kingdom
University of Manchester
Manchester University NHS Foundation Trust; Hull University Teaching Hospitals... and other collaborators

Completed

Saving Babies' Lives Project Impact and Results Evaluation: a Mixed Methodology Study (SPiRE)

Stillbirth

United Kingdom
Manchester University NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; Norfolk and Norwich University... and other collaborators

Completed

Flash-glucose Monitoring in Sub-optimally Controlled Type 1 Diabetes (FLASH-UK) (FLASH-UK)

Diabetes Mellitus, Type 1

United Kingdom
University Hospital Birmingham
Royal Free Hospital NHS Foundation Trust; University of Edinburgh; University...

Unknown

Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD (SPIRO-CKD)

Renal Insufficiency, Chronic | Cardio-Renal Syndrome

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Arthritis Research UK

Unknown

Acquired Immunodeficiency in ANCA Associated Vasculitis (ACQUIVAS)

Systemic Vasculitis
Liverpool University Hospitals NHS Foundation Trust
University Hospital Southampton NHS Foundation Trust

Completed

The Effect of Chemotherapy on Lactate Threshold in Cancer Patients

Cancer | Effects of Chemotherapy

United Kingdom
University Hospital Birmingham
British Heart Foundation

Unknown

Can Enhanced Glycemic Control in Type II Diabetics Improve Myocardial Protection During Coronary Artery Bypass Grafting? (GUIDE)

Type 2 Diabetes

United Kingdom
University Hospital Birmingham
British Heart Foundation

Completed

Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?

Cardiovascular Disease | Chronic Kidney Disease

United Kingdom
University Hospital Birmingham
British Heart Foundation

Unknown

Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Diabetes (DDCM)

Diabetic Cardiomyopathy

United Kingdom
University of Birmingham
Royal Marsden NHS Foundation Trust; The Leeds Teaching Hospitals NHS Trust; Guy... and other collaborators

Active, not recruiting

Measuring the Quality of Surgical Care and Setting Benchmarks for Training Using Intuitive Data Recorder Technology (MASTERY)

Cancer | Surgery

United Kingdom
Andrew Neilson
University of Oxford; University Hospitals Bristol and Weston NHS Foundation...

Completed

Handlebar Grip Related Injury Prevention (GRIP) Study: Are Exposed Metal Handlebar Ends a Risk Factor for Injury? (GRIP)

Wounds and Injuries | Child | Trauma | Children | Injuries
Royal Marsden NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; University Hospital Plymouth...

Unknown

Tissue Collection for Biomarkers Determining Resistance to Ibrutinib (CLARITY)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukaemia

United Kingdom
Queen's University, Belfast
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Recruiting

Co-morbidity and Refractory Asthma - UK Severe Asthma Registry (UKSAR)

Asthma

United Kingdom
University Hospital Southampton NHS Foundation...
AstraZeneca; Cancer Research UK

Completed

Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP Chemotherapy (ProCAID)

Prostate Cancer

United Kingdom
Prof. Janet Dunn
King's College Hospital NHS Trust; University of Manchester; University of Birmingham and other collaborators

Recruiting

Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes (REPAIR-MDS)

Myelodysplastic Syndromes (MDS)

United Kingdom
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? (D-CODE)

Vitamin D Deficiency | Crohn Disease

United Kingdom
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
Cardiff University
University of Birmingham; Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Primary Care Management of Lower Urinary Tract Symptoms in Men (PriMUS)

Lower Urinary Tract Symptoms

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Teenage/Young Adults (TYA) and Paediatric Patients With ALK Positive Cancers (DETERMINE)

Neoplasms by Histologic Type | Lymphoma | Lymphoproliferative Disorders | Neoplasms by Site | Renal Cell Carcinoma | Cancer | Solid Tumor | Anaplastic Large Cell Lymphoma | Neuroblastoma | Malignant Neoplasm | Haematological Malignancy

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Teenage/Young Adults and Paediatric Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition (DETERMINE)

Melanoma | Neoplasms by Histologic Type | Lymphoproliferative Disorders | Neoplasms by Site | Cancer | Colorectal Neoplasms | Endometrial Neoplasms | Malignant Neoplasm | Malignancy

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations (DETERMINE)

Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Gallbladder Neoplasms | Prostatic Neoplasm | Pancreatic Neoplasm | Lung Neoplasm | Haematological Malignancy | Urinary Bladder Neoplasm | Skin Neoplasm | Salivary Gland Neoplasm

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. (DETERMINE)

Glioma | Melanoma | Carcinoma, Non-Small-Cell Lung | Multiple Myeloma | Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Thyroid Cancer, Papillary | Thyroid Carcinoma, Anaplastic | Laryngeal Neoplasms | Erdheim-Chester Disease | Haematological Malignancy

United Kingdom
Ajinomoto Co., Inc.
Great Ormond Street Hospital for Children NHS Foundation Trust; Birmingham...

Active, not recruiting

Evaluation of Low Phenylalanine Formulas

Phenylketonurias

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. (DETERMINE)

Glioma | Melanoma | Neoplasms by Histologic Type | Lymphoproliferative Disorders | Neoplasms by Site | Cancer | Brain Neoplasms | Solid Tumor | Malignant Neoplasm | Malignancy | Haematological Malignancy

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol (DETERMINE)

Solid Tumor | Haematological Malignancy

United Kingdom
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; Welsh Burn Centre, Morriston Hospital, Swansea; St.... and other collaborators

Not yet recruiting

Examine the Validity of a Panel of Objective Burn Scar Measurement Tools (BOSS-2)

Burns | Scar | Hypertrophic
South Tyneside and Sunderland NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; South Tees Hospitals NHS Foundation... and other collaborators

Completed

ObeSity Related Colorectal Adenoma Risk (OSCAR)

Obesity | Colorectal Cancer | Metabolic Syndrome | Colorectal Neoplasm | Colorectal Adenoma | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
AstraZeneca; University of Sheffield; Cancer Research UK; University of Birmingham and other collaborators

Terminated

A Study of Selumetinib in Patients With Kaposi's Sarcoma (SCART)

AIDS-related Kaposi's Sarcoma

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Norfolk and Norwich University Hospitals... and other collaborators

Completed

Idiopathic Pulmonary Fibrosis Job Exposures Study (IPFJES)

Idiopathic Pulmonary Fibrosis | IPF

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK

Recruiting

Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer (PARTNER)

Breast Cancer

United Kingdom

Clinical Trials Sponsored by University Hospital Birmingham, NHS Foundation Trust, Hospital, Birmingham, UK

Sponsors and Collaborators

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