Search clinical trials for: フェーズ1

Total 48572 results

UCB Biopharma SRL

Not yet recruiting

A Study to Assess the Safety and Pharmacokinetics of a Single Dose of UCB9741 in Healthy Caucasian and Japanese Participants

Healthy Participants
UCB Celltech

Completed

A Study to Evaluate the Relative Bioavailability and Tolerability of Bimekizumab in Healthy Subjects

Healthy Volunteers

United Kingdom
UCB Biopharma S.P.R.L.

Completed

A Study to Test the Safety, Pharmacokinetics, and Pharmacodynamics of Single Ascending Intravenous Doses of UCB0107 in Healthy Male Subjects

Healthy Male Volunteers

Germany
Pfizer

Completed

ESTIMATION OF THE EFFECT OF MULTIPLE DOSE PF-06651600 ON THE PHARMACOKINETICS OF SINGLE DOSE MIDAZOLAM AND EFAVIRENZ

Healthy Subjects

United States
Abbott

Completed

Evaluation of the Bioavailability of Two ABT-072 Tablet Formulations as Compared to ABT-072 Capsule Formulation

Hepatitis C

United States
a2 Milk Company Ltd.

Completed

A1 Versus A2® Milk on the Gastrointestinal Physiology, Symptoms and Cognitive Behaviour for the Preschool Children

Gut Inflammation
Bayer

Completed

BAY 1902607: Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Bioavailability, Food Effect

Clinical Trials, Phase I as Topic

Germany
Bayer

Completed

First in Human Study to Investigate the Safety and Tolerability, Pharmacokinetics, Itraconazole Drug-drug-interaction and Food Effect of BAY1817080

Clinical Trials, Phase I as Topic

Germany
Hospital Italiano de Buenos Aires
University of Virginia; Universidad Nacional de La Plata; Universidad Nacional... and other collaborators

Completed

Artificial Pancreas in Latin America

Diabetes
Eli Lilly and Company

Completed

Trial of Pemetrexed and Carboplatin in Patients With Recurrent Ovarian or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cancer

Germany, Argentina, Canada, Poland, Sweden
Valneva Austria GmbH

Recruiting

Phase 1 Trial to Assess the Safety and Immunogenicity of an Inactivated, Adjuvanted Whole Zika Virus Vaccine Candidate (VLA1601) in Healthy Adults

Zika | Zika Virus Infection

United States
3D Medicines (Sichuan) Co., Ltd.

Completed

Phase I Study of KN035 in Chinese Subjects With Advanced Solid Tumors

Solid Tumors

China
UCB Biopharma S.P.R.L.

Completed

A Study to Test the Safety and Tolerability and Pharmacokinetics of Single Doses of UCB0107 in Healthy Japanese Subjects

Healthy Japanese Volunteers

United Kingdom
Balance Therapeutics

Completed

A Study to Investigate the Mass Balance of BTD-001 (HV103)

Molecular Mechanisms of Pharmacological Action

United Kingdom
University of British Columbia
Michael Smith Foundation for Health Research

Completed

SMART ERP for the Behavioral Treatment of Youth With Obsessive Compulsive Disorder (OCD)

Obsessive-Compulsive Disorder

Canada
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1a/1b Study of PPI-383 in Healthy Adults and Hepatitis C Patients

Hepatitis C, Chronic

United Kingdom, Mauritius
Kanyos Bio, Inc., a wholly-owned subsidiary of...

Completed

Assessment of KAN-101 in Celiac Disease (ACeD)

Celiac Disease

United States
Asan Medical Center

Completed

RAD001 in Combination With Capecitabine and Oxaliplatin (XELOX) in Patients With Advanced Gastric Cancer: RAD001+XELOX

Advanced Gastric Cancer

Korea, Republic of
U.S. Army Medical Research and Development Command
GlaxoSmithKline; United States Agency for International Development (USAID); Walter... and other collaborators

Completed

A Study to Determine the Effects of an Investigational Malaria Vaccine Given to Adults Living in the United States and Thereafter to Adults Living in Kenya

Malaria

United States, Kenya
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Drug Drug Interaction

United States, Sweden
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Safety Study of Multiple Subcutaneous (s.c.) Injections of SHR-1314 in Adults With Moderate-to-severe Plaque Psoriasis

Moderate-to-severe Plaque Psoriasis

China
Pfizer

Completed

Safety And PK Study Of CVX-060 In Patients With Advanced Solid Tumors

Neoplasms | Carcinoma | Cancer | Advanced Solid Tumors | Malignancy

United States
GeneQuantum Healthcare (Suzhou) Co., Ltd.

Recruiting

A Study of GQ1010 in Subjects With Advanced Solid Tumors

Advanced Malignant Solid Tumors

China
University of Southern California

Completed

Clinical and Pharmacokinetic Trial of Intra-Abdominal Irinotecan

Adenocarcinoma | Gastric Cancer

United States
University of Southern California
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Trial of Liposomal Doxorubicin (Doxil) and Weekly Docetaxel (Taxotere)

Carcinoma | Cancer

United States
Domain Therapeutics SA

Recruiting

DT-9081 Study in Participants With Advanced, Recurrent or Metastatic Solid Tumours (EPRAD)

Solid Tumor, Adult

France, Belgium
Jiangsu HengRui Medicine Co., Ltd.

Completed

The PK/PD Study of A Single Subcutaneous Injection of SHR-1209 in Healthy Subjects

Hypercholesteremia

China
University of Oslo
Oslo University Hospital; University of Oxford

Completed

Cysteine-lowering Treatment With Mesna (CYLOB)

Obesity | Drug Effect

Norway
Xenon Pharmaceuticals Inc.

Completed

Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101

Healthy Volunteers

United Kingdom
Apitope International NV
Quintiles, Inc.; European Commission

Completed

ATX-GD-59 in Patients With Graves Disease Not Treated With Anti-thyroid Therapy

Graves Disease

United Kingdom
Pfizer

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study Of PF-04427429 In Healthy Women Volunteers

Pain | Migraine Disorders

United States
Astellas Pharma Europe B.V.

Completed

EC905 Pharmacokinetic Profile Study

Healthy | Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia | Phase 1

Netherlands
Spectrum Pharmaceuticals, Inc

Terminated

Study of Poziotinib in Japanese Patients With NSCLC

NSCLC

Japan
Kathy Miller
Pfizer; Astex Pharmaceuticals, Inc.; Van Andel Institute Stand Up to Cancer Team

Completed

Study of ASTX727 Plus Talazoparib in Patients With Triple Negative or Hormone Resistant/HER2-negative Metastatic Breast Cancer

Metastatic Breast Cancer | Triple Negative Breast Cancer | Hormone Receptor Positive Tumor

United States
SecuraBio

Completed

Duvelisib in Hepatically Impaired Subjects Compared to Healthy Subjects (IPI-145-14)

Hepatic Impairment

United States
Gilead Sciences

Completed

Pharmacokinetics of Bictegravir in Adults With Normal and Impaired Renal Function

HIV

United States, New Zealand
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects

Healthy

United Kingdom
AstraZeneca

Completed

Phase I Multiple Ascending Dose Study for AZD 7268 in Healthy Volunteers

Healthy

United States
Celgene

Completed

Study to Evaluate the Pressor Effect of Oral Tyramine During Ozanimod Treatment in Healthy Adult Participants

Healthy Volunteers

United States
Pfizer

Terminated

Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer

Early Breast Cancer (Phase 2) | Advanced Breast Cancer (Phase 1b)

Spain, Sweden, Italy, Belgium
Institut Bergonié
PharmaMar

Completed

Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly Trabectedin Combined With Metronomic Cyclophosphamide (TARMIC)

Soft-tissue Sarcomas

France
Janssen Research & Development, LLC

Terminated

A Study of Decitabine (DACOGEN) in Sequential Administration With Cytarabine in Children With Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

France, United Kingdom, Spain, Belgium, Netherlands, Germany, Denmark
Pfizer

Completed

Study to Characterize Absorption, Distribution, Metabolism and Excretion of 14C PF-06651600 and to Evaluate the Absolute Oral Bioavailability and Fraction Absorbed of PF-06651600. (B7981011)

Healthy Volunteers

Netherlands
Institut National de la Santé Et de la Recherche...
EVI Industries, Inc.; BPRC; Recherche Clinique Paris Descartes Necker Cochin... and other collaborators

Completed

Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African Adults (AMA1-DiCo)

Malaria, Falciparum

Burkina Faso, France
Pfizer

Completed

A Study to Assess the Safety and Tolerability of Different Doses of PF-05402536 and PF-06413367 in Healthy Adult Smokers.

Smoking | Vaccines

Canada
Amgen

Completed

Single Dose Study of [14C]-Labelled AMG 706 in Patients With Advanced Solid Tumors

Advanced Solid Tumors
Immatics Biotechnologies GmbH

Recruiting

IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors

Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer

Germany
Bharat Biotech International Limited
Indian Council of Medical Research

Completed

Whole-Virion Inactivated SARS-CoV-2 Vaccine (BBV152) for COVID-19 in Healthy Volunteers (BBV152)

COVID-19 | SARS-CoV-2 Infection

India
AstraZeneca

Terminated

Study to Assess Safety, Tolerability and PK of AZD1480 in Patients With Solid Tumours

Solid Malignancies

United States
University of Edinburgh
NHS Lothian; NHS Greater Glasgow and Clyde

Completed

High-Sensitivity Cardiac Troponin On Presentation to Rule Out Myocardial Infarction (HiSTORIC)

Myocardial Infarction | Acute Coronary Syndrome

3

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