Search clinical trials for: Inherited retinal dystrophy

Total 6835 results

University of Campania "Luigi Vanvitelli"
Retina Italia Onlus

Completed

Natural History of Patients With Inherited Retinal Diseases Due to Mutations in RPE65 Gene (RPE65-NHS)

Leber Congenital Amaurosis 2 | Retinitis Pigmentosa 20

Italy
Nanoscope Therapeutics Inc.

Completed

Safety and Effects of a Single Intravitreal Injection of vMCO-010 Optogenetic Therapy in Subjects With Stargardt Disease (STARLIGHT)

Stargardt Disease

United States
Nanoscope Therapeutics Inc.

Enrolling by invitation

Non-interventional Long Term Follow-up Study of Participants Previously Enrolled in the STARLIGHT Study (SUSTAIN)

Stargardt Disease

United States
Columbia University

Active, not recruiting

Sildenafil for Treatment of Choroidal Ischemia

Age-related Macular Degeneration | Retinitis Pigmentosa | Vitelliform Macular Dystrophy | Choroidal Ischemia | Central Serous Retinopathy

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Batman Training and Research Hospital

Completed

The Efficacy of Hyperemesis Gravidarum on Macular Thickness, Corneal Thickness and Intraocular Pressure in Pregnancy

Corneal Dystrophy | Macular Dystrophy | Hyperemesis Gravidarum - Severe

Turkey
Retinagenix Holdings

Withdrawn

Safety and Efficacy of Zuretinol Acetate in Subjects With Inherited Retinal Disease

Retinal Disorder

United States
NightstaRx Ltd, a Biogen Company

Completed

Natural History of the Progression of Choroideremia Study (NIGHT)

Choroideremia

Finland, United States, Canada, Denmark, Netherlands, Germany, United Kingdom, Brazil, France
ProQR Therapeutics

Terminated

Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, United Kingdom
Wake Forest University Health Sciences

Terminated

Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only

Fuchs Dystrophy | Cystoid Macular Edema

United States
Mayo Clinic
National Eye Institute (NEI)

Completed

Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.

Retinal Disease | Best Vitelliform Macular Dystrophy | Bestrophinopathy | Adult Onset Vitelliform Macular Dystrophy | Autosomal Dominant Vitreoretinalchoroidopathy

United States
ProQR Therapeutics

Active, not recruiting

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Netherlands, United Kingdom, Germany
GenSight Biologics

Active, not recruiting

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year (REFLECT)

Leber Hereditary Optic Neuropathy

Belgium, Spain, United States, France, United Kingdom, Taiwan, Italy
ProQR Therapeutics

Active, not recruiting

A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene (AURORA)

Eye Diseases | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies | Vision Disorders | Retinal Disease | Autosomal Dominant Retinitis Pigmentosa | Vision Tunnel

United States
Moorfields Eye Hospital NHS Foundation Trust

Completed

Dual Wavelength OCT

Retinal Degeneration | Diabetic Retinopathy | Retinal Dystrophies | AMD

United Kingdom
Biogen

Completed

Natural Disease Progression in Participants With Choroideremia

Choroideremia

United States
Astellas Institute for Regenerative Medicine

Completed

Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Astellas Institute for Regenerative Medicine

Completed

Sub-retinal Transplantation of hESC Derived RPE(MA09-hRPE)Cells in Patients With Stargardt's Macular Dystrophy

Stargardt's Macular Dystrophy

United States
GenSight Biologics

Completed

REALITY LHON Registry (REALITY)

Leber Hereditary Optic Neuropathy

United States, France, Italy, Spain, United Kingdom
Benha University

Unknown

BEOVU in the Treatment of Dystrophy-related Macular Neovascular Degeneration

Dystrophy, Retinal

United Arab Emirates
Astellas Institute for Regenerative Medicine

Completed

A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Pfizer

Terminated

An Open-label Extension Study To Evaluate Safety Of PF-06252616 In Boys With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

United States, Canada, United Kingdom, Japan, Italy
Astellas Institute for Regenerative Medicine

Completed

Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Stargardt Macular Dystrophy Patients

Stargardt's Macular Dystrophy

United States
University of Utah

Completed

Phase 1 Pilot Study of 4-MP to Treat Stargardt Macular Dystrophy

Macular Dystrophy, Corneal

United States
Escuela Neijing

Completed

Efficacy of Acupuncture in Macular Diseases (AMAD)

Age-related Macular Degeneration | Stargardt Disease | Macular Dystrophy

Colombia
National Eye Institute (NEI)

Completed

Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases

Corneal Dystrophies, Hereditary | Corneal Disease

United States, China, Italy
MD Stem Cells

Unknown

Stem Cell Ophthalmology Treatment Study (SCOTS)

Glaucoma | Macular Degeneration | Retinal Disease | Hereditary Retinal Dystrophy | Optic Nerve Disease

United States
University of Michigan

Completed

Optical Head-Mounted Display Technology for Low Vision Rehabilitation

Healthy | Retinal Dystrophies

United States
VA Office of Research and Development

Completed

Complement Factor H Haplotypes and Smoking in Age-related Macular Degeneration (CFH&AMD)

Macular Degeneration

United States
Sultan Qaboos University

Completed

Intravitreal Ranibizumab (Lucentis®) in the Treatment of Non-leaking Macular Cysts in Retinal Dystrophy

Retinal Dystrophies
Pixium Vision SA

Completed

Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal Dystrophy (IRIS 2)

Retinitis Pigmentosa | Choroideremia | Cone Rod Dystrophy

Austria, Spain, United Kingdom, France, Germany
Wills Eye
Retina Implant AG

Withdrawn

RETINA IMPLANT Alpha AMS in Blind Patients With Retinitis Pigmentosa

Retinitis Pigmentosa

United States
University of Iowa
University of South Florida; National Institute of Neurological Disorders and... and other collaborators

Completed

Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS) (DSI and HMSN)

Charcot Marie Tooth Disease | Inherited Peripheral Neuropathy

United States, United Kingdom
Johns Hopkins University
The Shulsky Foundation

Completed

The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4: PROM1-Related Macular Dystrophy (ProgStar-4)

Stargardt Disease

Germany, United States, United Kingdom
Baylor Research Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Unknown

The Natural History of Mucolipidosis Type IV

Mucolipidosis Type IV

United States
University of Utah

Completed

DHA Supplementation in Patients With STGD3

Dominantly Inherited Stargardt's Disease (STGD3)

United States
National Eye Institute (NEI)

Completed

Molecular Genetics of Retinal Degenerations

Retinal Degeneration | Retinitis Pigmentosa

United States, India, Pakistan, China
Southwest Hospital, China

Unknown

Clinical Study of Subretinal Transplantation of Human Embryo Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Macular Degeneration Diseases

Macular Degeneration | Stargardt's Macular Dystrophy

China
The Cleveland Clinic
National Eye Institute (NEI)

Completed

PIONEER: Intraoperative and Perioperative OCT Study (PIONEER)

Retinal Detachment | Epiretinal Membrane | Fuchs Endothelial Dystrophy | Macular Hole

United States
Pixium Vision SA

Completed

Restoring Vision With the Intelligent Retinal Implant System (IRIS V1)in Patients With Retinal Dystrophy (IRIS-1)

Retinitis Pigmentosa | Choroideremia | Cone Rod Dystrophy

Austria, France, Germany
National Eye Institute (NEI)

Completed

Color Vision as a Measure for Inherited Retinal Diseases

Healthy Volunteer | Retinal Disease | Inherited Retinal Degeneration

United States
Catholic University of the Sacred Heart

Unknown

Saffron Supplementation in Stargardt's Disease (STARSAF02)

Retinal Degeneration | Genetic Disease | Single-Gene Defects | Macular Dystrophy

Italy
National Eye Institute (NEI)

Completed

Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy

Macular Degeneration

United States
National Eye Institute (NEI)

Completed

Potential Research Participants for Future Studies of Inherited Eye Diseases

Glaucoma | Macular Degeneration | Retinitis Pigmentosa | Cataract | Strabismus

United States
Optos, PLC
Johns Hopkins University; University of Southern California

Completed

Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO

Age-Related Macular Degeneration | Diabetic Retinopathy | Macular Edema | Retinal Vein Occlusion | Geographic Atrophy | Epiretinal Membrane | Macular Hole | Pattern Dystrophy of Macula | Central Serous Retinopathy

United States
University of Michigan
Midwest Eye Banks

Terminated

Novel Quantification Methods for Fluorescence to Detect Progression in Stargardt Disease

Stargardt Disease

United States
University of New Mexico

Completed

Visual Activity Evoked by Infrared in Humans After Dark Adaptation

Retinitis Pigmentosa | Age Related Macular Degeneration | Congenital Stationary Night Blindness | Colorblindness

United States
QLT Inc.

Completed

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Leber Congenital Amaurosis (LCA) | Retinitis Pigmentosa (RP)

United States, Canada, Denmark, Germany, Netherlands, Switzerland, United Kingdom
University College, London
Moorfields Eye Hospital NHS Foundation Trust; Targeted Genetics Corporation

Completed

Safety Study of RPE65 Gene Therapy to Treat Leber Congenital Amaurosis

Retinal Degeneration

United Kingdom
Nantes University Hospital

Completed

Clinical Gene Therapy Protocol for the Treatment of Retinal Dystrophy Caused by Defects in RPE65 (RPE65)

Leber Congenital Amaurosis

France

Search clinical trials for: Inherited retinal dystrophy

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