Search clinical trials for: Leukapheresis

Total 171 results

GlaxoSmithKline
Merck Sharp & Dohme LLC

Terminated

Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple Myeloma

Neoplasms

United States
National Institute of Allergy and Infectious Diseases...
Applied Immunesciences

Completed

A Phase I Study of Autologous, Activated CD8(+) Lymphocytes Expanded In Vitro and Infused With or Without Recombinant Interleukin-2 to Patients With AIDS or Severe ARC

HIV Infections

United States
Washington University School of Medicine
Bristol-Myers Squibb

Terminated

Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Glioblastoma

United States
GlaxoSmithKline

Completed

Letetresgene Autoleucel Engineered T Cells in NY-ESO -1 Positive Advanced Non-Small Cell Lung Cancer (NSCLC)

Neoplasms

United States
Cancer Research UK

Completed

A Phase I Trial of Anti-GD2 T-cells (1RG-CART)

Relapsed or Refractory Neuroblastoma

United Kingdom
DGTI - Haemapheresis Vigilance Working Party
Aix Scientifics

Active, not recruiting

Multinational Haemapheresis Vigilance Study

Blood Donation With Hemapheresis
University of Melbourne
Johns Hopkins University; Oregon Health and Science University; University of... and other collaborators

Completed

HIV Persistence in Lymph Node and Peripheral Blood (HIV-PRADA)

HIV-1-infection

Australia
Siddhartha Ganguly

Completed

Exploratory Trial to Estimate Proportion of Patients With Tumor Cell Contaminated Leukapheresis Products With and Without Bortezomib With In-vivo Purging - Multiple Myeloma (MM)

Multiple Myeloma

United States
SOTIO a.s.

Completed

DCVAC/OvCa After Standard-of-care Chemotherapy in Women With Relapse of Platinum-sensitive Epithelial Ovarian Cancer

Ovarian Cancer Recurrent

Czechia
National Cancer Institute (NCI)

Terminated

Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Neoplasms, Squamous Cell | Squamous Lntraepithelial Lesions of Vulva | Vulvar HSIL

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Trial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macrophage Colony-stimulating Factor (GM-CSF)-Based Myeloma Cellular Vaccine in the Autologous Transplant Setting in Multiple Myeloma (aMILs)

Multiple Myeloma

United States
Memorial Sloan Kettering Cancer Center

Terminated

Collection and Generation of Antigen-specific T-lymphocyte Cell Lines From Primary, Third-party, Related, and Unrelated Donors

Healthy

United States
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.

Terminated

Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation (deLTa)

Liver Transplantation

United States
American Gene Technologies International Inc.

Unknown

Developing a Functional Cure for HIV Disease: Clinical Specimen Collection From HIV Positive Individuals

HIV Infections

United States
Jonsson Comprehensive Cancer Center

Completed

Vaccine Therapy in Treating Patients With Stage IV or Relapsed Malignant Melanoma

Melanoma

United States
Jonsson Comprehensive Cancer Center
Novartis Pharmaceuticals

Withdrawn

TCR Genetically Engineered PBMC and PBSC After Melphalan Conditioning Regimen in Treating Participants With Relapsed and Refractory Multiple Myeloma (NYSCT MM)

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | HLA-A*0201 Positive Cells Present | NY-ESO-1 Positive Tumor Cells Present

United States
Stem Cells Arabia

Unknown

Transplantation of Autologous Bone Marrow or Leukapheresis-Derived Stem Cells for Treatment of Spinal Cord Injury

Spinal Cord Injury

Jordan
University of Washington
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients Receiving Trastuzumab For HER2-Positive Stage IIIB-IV Breast Cancer

HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer

United States
National Institute of Allergy and Infectious Diseases...

Terminated

LCI Apheresis to Obtain Plasma or White Blood Cells

Apheresis

United States
National Institute of Diabetes and Digestive and...

Terminated

Stem Cell Collection

Stem Cells

United States
M.D. Anderson Cancer Center
Intrexon Corporation

Terminated

Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia

Acute Myeloid Leukemia | Hematopoietic/Lymphoid Cancer

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Completed

Phase I Study of HIV 1 Antigen Expanded Specific T Cell Therapy (HXTC)

HIV

United States
Imperial College London

Completed

Adult Stem Cell Therapy in Liver Insufficiency

Liver Cirrhosis

United Kingdom
Northwestern University

Terminated

Procurement of Leukapheresis Products From End Stage Liver Disease (ESLD) Patients for Immunological Studies

End Stage Liver Disease

United States
Aeras

Completed

Biological Samples Obtained by Leukapheresis Induced by Two BCG Vaccinations in BCG-naïve Healthy Adults in the US ((A-051))

Tuberculosis

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating Patients With Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Washington University School of Medicine
Merck Sharp & Dohme LLC

Withdrawn

Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung Cancer

NSCLC | Non Small Cell Lung Cancer | Non-small Cell Lung Cancer | Small Cell Lung Extensive Stage
Memorial Sloan Kettering Cancer Center

Completed

Consolidation Therapy With Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19 in Patients With Chronic Lymphocytic Leukemia Following Upfront Chemotherapy With Pentostatin, Cyclophosphamide and Rituximab

Leukemia

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Collection of Blood, Bone Marrow, Leukapheresis, and Tissue Biopsy Samples From Patients and Their Family Members for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases Laboratory Research Studies

Idopathic Inflammatory/Autoimmune Syndromes

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Two Different Methods of Collecting Stem Cells For an Autologous Stem Cell Transplant in Treating Patients With Diffuse Large Cell Lymphoma

Lymphoma

United States
TriStar Health

Withdrawn

Pilot Study of Stem Cell Transplantation for Children and Young Adults With Refractory Crohn's Disease.

Crohn's Disease
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Rituximab, Combination Chemotherapy, Filgrastim (G-CSF), and Plerixafor in Treating Patients With Non-Hodgkin Lymphoma Undergoing Mobilization of Autologous Peripheral Blood Stem Cells

Non-Hodgkin Lymphoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Melphalan, Total Marrow Irradiation, and Autologous Stem Cell Transplantation in Treating Patients With High-Risk Multiple Myeloma

Plasma Cell Myeloma | Plasma Cell Leukemia in Remission

United States
National Institute of Allergy and Infectious Diseases...

Completed

Leukapheresis for Research on HCV-Coinfected Patients

HIV Infections | Hepatitis C

United States
M.D. Anderson Cancer Center

Completed

CD19-specific T-cell for Chronic Lymphocytic Leukemia (CLL)

Leukemia | Advanced Cancers

United States
Seoul National University Hospital

Completed

Recruiting Blood Donor With Allogeneic Natural Killer Cell

Healthy Volunteers

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up

Chronic Granulomatous Disease | Communicable Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection

HIV Infection

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART

HIV-1 Infection

United States
University of Kansas Medical Center

Completed

Evaluate Rituximab in Obtaining PCR (Polymerase Chain Reaction) Negative Leukapheresis Product in Patients With Relapsed Follicular Lymphoma

Non-Hodgkins Lymphoma

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Stage IV Breast Cancer

HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer

United States
University of Washington
National Cancer Institute (NCI)

Completed

Bendamustine Hydrochloride, Etoposide, Dexamethasone, and Filgrastim For Peripheral Blood Stem Cell Mobilization in Treating Patients With Refractory or Recurrent Lymphoma or Multiple Myeloma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Completed

Immune Response After Stem Cell Transplant in HIV-Positive Patients With Hematologic Cancer

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm

United States
H. Lee Moffitt Cancer Center and Research Institute
ESP Pharma

Terminated

Busulfan Monotherapy as Conditioning for Autologous Hematopoietic Progenitor Cell Transplantation

Acute Myeloid Leukemia (AML)

United States
Edward Ziga

Terminated

Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors

Glioma | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | High Grade Glioma

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Adjuvant Therapy of Pegylated Interferon- 2b Plus Melanoma Peptide Vaccine

Melanoma

United States
Nationwide Children's Hospital

Withdrawn

Autologous Stem Cell Transplant for Refractory Crohn's Disease

Crohn's Disease
Washington University School of Medicine

Completed

Granulocyte Colony-stimulating Factor (G-CSF) Plus or Minus AMD3100 for Engraftment Post Allogeneic Transplant

Stem Cell Transplant Patients

United States
Memorial Sloan Kettering Cancer Center

Completed

Assess the Feasibility and Safety of Granulocyte Colony Stimulating Factor (GCSF) Mobilization of CD34+ Hematopoietic Progenitor Cells in Patients With Betathalassemia Major

Beta Thalassemia Major | Congenital Anemias

United States
Hospices Civils de Lyon

Completed

Higher Percentage of CD34+ CD38- Cells Detected by Multiparameter Flow Cytometry From Leukapheresis Products Predicts Unsustained Complete Remission in Acute Myeloid Leukemia

Acute Myeloid Leukemia

France

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