Search clinical trials for: Lp-PLA2

Total 984 results

AstraZeneca

Unknown

ZD 1839 Plus Chemotherapy in Treating Patients With Non-Small Cell Lung Cancer

Lung Cancer

United States
Bristol-Myers Squibb

Completed

Drug-Drug Interaction (DDI) w/Ketoconazole or Fluconazole

Alzheimer Disease

United States
Biogen

Completed

A Study to Assess the Potential for Gastric-pH Dependent Drug-Drug Interactions of BIIB122 With a Proton Pump Inhibitor in Healthy Participants

Healthy Volunteer

United States
Medline Industries

Completed

Durability of Two Skin Barrier Protectants (SBP)

Skin Hydration in Healthy Volunteers

United States
Alexion
PPD; ERT: Clinical Trial Technology Solutions

Completed

A Study of the Cardiac Effects of ALXN1840 in Healthy Adults

Healthy

United States
Bristol-Myers Squibb

Completed

A Study to Determine the Effect of Famotidine on the Drug Levels of BMS-986256 in Healthy Participants

Healthy Participants

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of Single and Multiple Doses of BMS-986209 in Healthy Participants

Health Participants

United States
Bristol-Myers Squibb

Completed

A Study to Assess Administration of an Oral Anti-thrombotic With Antiplatelet Therapy in Healthy Subjects

Healthy Volunteers

United States
Kowa Research Institute, Inc.

Completed

Study to Assess the Food Effect of K-877 in Healthy Adult Volunteers

Healthy

United States
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Mitapivat (AG-348) in Healthy Adult Participants

Healthy Volunteers

United States
Kowa Research Institute, Inc.

Completed

Pharmacokinetic Drug-Drug Interaction Study Between K-877 and CSG452 in Healthy Adult Volunteers

Healthy

United States
Celgene

Completed

Bioavailability of Enasidenib (CC-90007) Sprinkle Formulation Relative to the Reference Tablet Formulation and Effect of Food on the Pharmacokinetics of Sprinkle Formulation in Healthy Adults

Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

Bioavailability of Apixaban Sprinkle Compared to Apixaban Capsules

Healthy Volunteers

United States
Celgene

Terminated

Phase 1 Study of CC-90005 in Healthy Subjects and Subjects With Moderate to Severe Plaque-type Psoriasis

Healthy Volunteers | Parapsoriasis

United States
Oscotec Inc.
PPD

Completed

Safety, Tolerability, and Pharmacokinetics of a Single Oral Dose of SKI-O-703 in Healthy Volunteers

Rheumatoid Arthritis

United States
Oscotec Inc.
PPD

Completed

Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of SKI-O-703 in Healthy Volunteers

Arthritis, Rheumatoid

United States
Melinta Therapeutics, Inc.

Completed

Study to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects

VA Drug Interactions

United States
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates

Rheumatoid Arthritis

United States
AstraZeneca

Completed

Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)

Diabetes Mellitus

United States
AstraZeneca

Completed

Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR

Diabetes Mellitus

United States
AstraZeneca

Completed

Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants

Type 2 Diabetes Mellitus

United States
AstraZeneca

Unknown

ZD 1839 Plus Combination Chemotherapy in Treating Patients With Non-Small Cell Lung Cancer

Lung Cancer

United States
Regado Biosciences, Inc.

Completed

Safety, Tolerability and PK/PD of RB006 in a Healthy Volunteer SAD (SC101)

Healthy Volunteer

United States
Phathom Pharmaceuticals, Inc.

Completed

A Study to Determine the Bioavailability of Vonoprazan Sprinkle Capsules on Pudding or on Applesauce Relative to a Vonoprazan Tablet in Healthy Participants

Healthy Volunteers

United States
BeiGene

Completed

A Study to Investigate the Absorption, Metabolism and Excretion of [14C]-BGB-11417

Healthy Volunteers

United States
Phathom Pharmaceuticals, Inc.

Completed

Evaluation of Effect of Vonoprazan on Midazolam Pharmacokinetics in Healthy Participants

Healthy Volunteers

United States
Medline Industries

Completed

Wet Time for a Foam Hand Sanitizer

Hand Hygiene Effectiveness

United States
Galderma R&D

Completed

A Treatment for Severe Inflammatory Acne Subjects

Acne Vulgaris

United States
Celltrion

Completed

To Compare the Pharmacokinetics and Safety of the Auto-injector and Pre-filled Syringe of CT-P17

Healthy

United States
Array Biopharma, now a wholly owned subsidiary...

Completed

A Safety Study of ARRY-300 in Healthy Subjects

Healthy

United States
Celltrion

Completed

CT-P13 (Infliximab) Subcutaneous Administration by Pre-filled Syringe and Auto-injector in Healthy Subjects

Health, Subjective

United States
Cerevance Beta, Inc.

Completed

Study of CVN424 in Healthy Subjects (CVN424)

Healthy

United States
Kowa Research Institute, Inc.

Completed

Evaluate the Safety, Tolerability, & Pharmacokinetics of K-285 Compared With Indomethacin Capsule in Healthy Adults

Healthy

United States
AstraZeneca
Bristol-Myers Squibb

Completed

Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of Ultra Low Doses of Dapagliflozin in Healthy Subjects (ULDS)

Type 2 Diabetes

United States
Bristol-Myers Squibb

Completed

Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BMS-986120 in Healthy Subjects and the Effects of Co-Administration of Midazolam and BMS-986120

Healthy Adult Volunteers

United States
AstraZeneca

Completed

Bioequivalence Study of Fixed Dose Combination of 2.5 mg Saxagliptin/850 mg Metformin Tablet Relative to 2.5 mg Onglyza and 850 mg Glucophage Tablets Co-Administered

Type 2 Diabetes Mellitus

United States
Celgene Corporation

Completed

First-in-human Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of CC-90001

Healthy Volunteers

United States
AstraZeneca

Completed

ZD9331 With or Without Topotecan in Treating Patients With Refractory or Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United States
Bristol-Myers Squibb

Completed

Safety Study to Evaluate BMS-830216 in Healthy Subjects

Obesity

United States
Bristol-Myers Squibb

Completed

Drug-Drug Interaction Study in Healthy Subjects

Hepatitis C

United States
Miltenyi Biomedicine GmbH
City of Hope Comprehensive Cancer Center

Not yet recruiting

M-2018-334 in Hematological Malignancies (HAPLO2022)

Hematological Malignancies
Abiomed Inc.

Terminated

Protect II, A Prospective, Multicenter Randomized Controlled Trial (PROTECT II)

Coronary Artery Disease

United States, Netherlands, Canada
Medicrea International

Active, not recruiting

The Degen Study: Post-market Clinical Follow-up on the PASS LP, PASS Degen and PASS Tulip Systems (PASS DEGEN) (PASS DEGEN)

Spinal Deformity | Spinal Degeneration | Thoracolumbar Disc Degeneration | Thoracolumbar Spondylolisthesis

France
Lantern Pharma Inc.

Recruiting

Study of LP-184 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

United States
Lipella Pharmaceuticals, Inc.

Completed

The Safety, Tolerability and Efficacy of LP-10 in Subjects With Refractory Moderate to Severe Hemorrhagic Cystitis

Hemorrhagic Cystitis

United States
Pulmonx Corporation

Completed

Post-Market Clinical Evaluation of the Zephyr Valve 5.5-LP EBV

Pulmonary Emphysema

United Kingdom, Switzerland, Germany
Novartis Pharmaceuticals

Not yet recruiting

Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD

Elevated Lp(a) and Established Atherosclerotic Cardiovascular Disease
Purdue Pharma LP

Completed

The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) on QT Intervals in Healthy Volunteers

Healthy Volunteers

United States
University of Wisconsin, Madison

Active, not recruiting

Expressive Writing Intervention Study

Distress, Emotional

United States
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Healthy

United States

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