Search clinical trials for: Microenvironment

Total 171 results

Center Eugene Marquis

Withdrawn

Contribution of [18F]DPA-714 PET for Grading and Exploration of the Inflammatory Microenvironment of Glioma. (INFLAGLI)

Glioma
Dan Zandberg
Bristol-Myers Squibb

Active, not recruiting

Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy

Squamous Cell Carcinoma of the Head and Neck

United States
Institut Bergonié

Active, not recruiting

Integrative Analysis of Tumor Microenvironment and Optimization of Immunotherapy Duration in NSCL Cancer Patients (OPTIMUNELUNG)

Non Small Cell Lung Cancer

France
Affiliated Hospital of Nantong University

Enrolling by invitation

Clinical Study of Lung Protective Ventilation Strategies and Tumor Microenvironment

Tumor Microenvironment

China
Renmin Hospital of Wuhan University

Completed

A Study of the Tumor Microenvironment Affecting the Efficacy of Immunotherapy for Esophageal Cancer

Esophageal Cancer

China
Guangdong Women and Children Hospital

Completed

Effect of Autologous Cord Blood-mononuclear Cells Infusion on Immune Microenvironment in Infants Born Very Preterm in NICU

Immunomodulation Effect

China
Shanghai 10th People's Hospital

Completed

Clinical Study of Fecal Microbiota Transplantation in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO)

Small Intestinal Bacterial Overgrowth | Fecal Microbiota Transplantation

China
National Cancer Institute (NCI)

Enrolling by invitation

Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment

Melanoma | Pancreatic Cancer | Lung Cancer | Solid Tumors | Gastrointestinal Cancer | Hematologic Malignancy | Liver Cancer | Pre-Malignancy

United States
Presage Biosciences
Takeda

Completed

PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC

Head and Neck Squamous Cell Carcinoma

United States
Regenexx, LLC

Terminated

Correlating the OA Knee Microenvironment to Outcomes After Regenexx-SD Treatment: A Multi-Site Study

Knee Osteoarthritis

United States
Shanghai 10th People's Hospital

Completed

Clinical Study of Fecal Microbiota Transplantation in the Treatment of Antibiotic-associated Diarrhea

Antibiotic-associated Diarrhea | Fecal Microbiota Transplantation

China
University Health Network, Toronto
Celsius Therapeutics

Active, not recruiting

Renal Cell Carcinoma Microenvironment Discovery Project (REMEDY)

Renal Cell Carcinoma

Canada
TME Pharma AG

Active, not recruiting

Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patients (GLORIA)

Glioblastoma

Germany
Mina Alpha Limited

Active, not recruiting

A Study of MTL-CEBPA in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumours (TIMEPOINT) (TIMEPOINT)

Solid Tumor, Adult

United Kingdom
Institut Bergonié
PharmaMar

Completed

Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly Trabectedin Combined With Metronomic Cyclophosphamide (TARMIC)

Soft-tissue Sarcomas

France
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Study of the Association Between Tumor Microenvironment Macrophages and Treatment Response in Squamous Cell Carcinoma of the Anal Canal (MACARAN)

Squamous Cell Carcinoma

France
Centre Hospitalier Universitaire Vaudois

Active, not recruiting

Analysis of the Modulation of the Tumor Microenvironment by MK-3475 (Pembrolizumab) Using a Systems Biology Approach (PEMSYS)

Metastatic Melanoma Naive to Immune Therapy in Metastatic Setting

Switzerland
Institut Claudius Regaud

Completed

Modifications of Immune Microenvironment Induced by Neoadjuvant Chemotherapy in Triple-negative BC (MIMOSA)

Triple Negative Breast Cancer

France
University Ghent
Belgian Federation Against Cancer

Completed

Role of the Peritoneal Microenvironment in the Pathogenesis and Spread of Colorectal Carcinomatosis (MMT)

Peritoneal Carcinomatosis

Belgium
National Cancer Institute (NCI)

Completed

Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas

Diffuse Large B-Cell Lymphoma | Hodgkin Lymphoma

United States
Helix BioPharma Corporation
KCR S.A.

Terminated

A Study of L-DOS47 in Combination With Vinorelbine/Cisplatin in Lung Adenocarcinoma

Lung Adenocarcinoma

Poland, Ukraine
Presage Biosciences
Takeda

Completed

Intratumoral Microdosing of TAK-981 in Head and Neck Cancer

Head and Neck Cancer

United States
Regenexx, LLC

Completed

Correlating the Osteoarthritic Knee Microenvironment to Clinical Outcome After Treatment With Regenexx®SD Treatment (KneeOA)

Osteoarthritis, Knee
Presage Biosciences
Takeda

Withdrawn

CIVO Intratumoural Microdosing of Anti-Cancer Therapies in Australia

Solid Tumour

Australia
Presage Biosciences
Bristol-Myers Squibb; Celgene

Terminated

Intratumoral Microdosing of Motolimod in HNSCC

HNSCC

United States
Hartford Hospital
University of Maryland; University of Connecticut

Completed

Vaginal Probiotics and Pessaries and Their Impact on the Vaginal Microenvironment

Inflammatory Response | Pelvic Organ Prolapse | Dysbiosis

United States
Hunan Province Tumor Hospital

Completed

Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

China
Massachusetts General Hospital
Harvard School of Public Health (HSPH)

Withdrawn

OMega-3 Fatty Acid for the Immune Modulation of Colorectal Cancer (OMICC)

Colon Cancer

United States
University of Wisconsin, Madison
American Cancer Society, Inc.

Terminated

Alterations in the Vaginal Microenvironment Using a Non-pharmacological Intervention

Adherence, Medication

United States
Presage Biosciences
Northwell Health; Oregon Health and Science University; University of Washington and other collaborators

Completed

Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma

Soft Tissue Sarcoma Adult

United States
Australasian Gastro-Intestinal Trials Group

Completed

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer (MODULATE)

Colorectal Cancer Metastatic

Australia
National Cancer Centre, Singapore
Singapore Clinical Research Institute

Completed

Prospective Cohort Study on the Clinical Trajectory of Resected Hepatocellular Carcinoma (PLANET)

Hepatocellular Carcinoma

Singapore, Malaysia, Philippines, Thailand
Istituto Scientifico Romagnolo per lo Studio e...
ERA PERMED

Active, not recruiting

InteGRAtive Analysis of tuMor, Microenvironment, immunitY and Patient Expectation for Personalized Response Prediction in Gastric Cancer (GRAMMY)

Gastric Cancer

France, Greece, Italy
Huashan Hospital

Unknown

The Study of Microglia/Macrophages Involved Dynamic Evolution of Glioma Microenvironment and the Function and Visualization of Targeted Molecules of Glioma

Glioma

China
Central Hospital, Nancy, France

Unknown

Study of the Inflammatory Microenvironment in Atypical Meningiomas

Atypical Meningioma

France
Surface Oncology

Completed

Study of SRF231 in Patients With Advanced Solid and Hematologic Cancers

Hematologic Cancers | Advanced Solid Cancers

United States, Canada
Helse Stavanger HF
Helse-Bergen HF

Enrolling by invitation

Prospective Breast Cancer Biobanking (PBCB)

Breast Cancer

Norway
TME Pharma AG
Merck Sharp & Dohme LLC

Completed

Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancer (Keynote-559)

Metastatic Colorectal Cancer | Metastatic Pancreatic Cancer

Germany
Guangzhou Institute of Respiratory Disease
GeneCast Biotechnology Co., Ltd.

Unknown

Correlation Between Specific Gene Mutationand Local Immune Microenvironment and Immunotherapy Efficacy in NSCLC

NSCLC

China
University of Khartoum
University of York

Completed

Tissue Microenvironment Signatures of the Mycetoma Granuloma

Mycetoma

Sudan
Charite University, Berlin, Germany
Erwin Braun foundation

Completed

Moderate Whole Body Hyperthermia for Patients Undergoing Re-irradiation for Head and Neck Cancer -Influence on the Tumor Microenvironment (GKH-TMM)

Head and Neck Neoplasms | Recurrence Tumor

Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Withdrawn

Safety and Tolerability Study of Nivolumab and Cabiralizumab for Resectable Biliary Tract Cancer

Resectable Biliary Tract Cancer
Peking University People's Hospital

Unknown

Tumor Immune Mechanism of Axillary Lymph Node Metastasis in Early Luminal Type A Breast Cancer

Lymph Node Metastases | Immune Microenvironment | Luminal A

China
University Hospital, Montpellier

Completed

Long Term Effects and of a Pulmonary Rehabilitation Maintenance Program (LTAir+R)

Chronic Respiratory Disease

France
Weill Medical College of Cornell University
Cambridge University Hospitals NHS Foundation Trust

Terminated

To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas

Pancreas Cancer

United States, United Kingdom
Helix BioPharma Corporation
Theradex

Completed

A Dose Escalation Study of L-DOS47 in Recurrent or Metastatic Non-Squamous NSCLC

Non-Small Cell Lung Cancer

United States
University Hospital Center of Martinique
European Georges Pompidou Hospital

Completed

Changes in the Microenvironment of HPV-induced Head and Neck Cancers in West Indies and Metropolitan Population (MituHPV)

Immunotherapy

France, Martinique
Washington University School of Medicine

Terminated

A Study of Granix to Disrupt the Bone Marrow Microenvironment in Patients With Multiple Myeloma Undergoing Autologous Transplantation

Multiple Myeloma

United States
Universiti Kebangsaan Malaysia Medical Centre
Ministry of Education, Malaysia; B-Crobes Laboratory Sdn. Bhd; Fibronostics Pte...

Unknown

The Effect of Probiotics on the Clinical Outcomes and Gut Microenvironment in Patients With Fatty Liver

Non-Alcoholic Fatty Liver Disease

Malaysia
Neuromed IRCCS

Unknown

Targeting Potassium Channels to Reprogram Glioblastoma Microenvironment: in Vitro and in Vivo Studies

Cancer of Head and Neck

Italy

3

Subscribe