Search clinical trials for: Phase I, Healthy Volunteers

Total 45882 results

Graviton Bioscience Corporation

Completed

Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Dose of GV101 in Healthy Subjects

Phase 1

United States
DICE Therapeutics, Inc.

Completed

Mass Balance and Pharmacokinetics (PK) of [14C]-DC-806 in Healthy Male Participants

Healthy Volunteers

Netherlands
DICE Therapeutics, Inc.

Completed

A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants

Healthy Volunteers

United States
Revolo Biotherapeutics

Completed

Safety, Tolerability, and Pharmacokinetics of IRL201104 in Healthy Volunteers

Healthy Volunteer

United States
Liverpool School of Tropical Medicine
Liverpool University Hospitals NHS Foundation Trust; Covance; Eisai Limited; Subiaco... and other collaborators

Terminated

Development of AWZ1066S, a Small Molecule Anti-Wolbachia Candidate Macrofilaricide Drug (AWOL)

Onchocerciasis | Filariasis, Lymphatic

United Kingdom
Celgene

Completed

Study to Evaluate the Pressor Effect of Oral Tyramine During Ozanimod Treatment in Healthy Adult Participants

Healthy Volunteers

United States
Kyowa Kirin Co., Ltd.

Completed

A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis

Healthy Men and Subjects With Ulcerative Colitis

Japan
Cassava Sciences, Inc.
Worldwide Clinical Trials

Completed

Food Effect and Bioequivalence Study of Simufilam Tablets in Healthy Volunteers

Healthy Volunteers

United States
Sinew Pharma Inc.

Completed

Phase I Pharmacokinetic Study of HUYPS-1 in Healthy Volunteers

Nonalcoholic Steatohepatitis

Taiwan
Portola Pharmaceuticals

Completed

A Human Phase I Absolute Bioavailability Study of PRT054021 in Healthy Male Volunteers

Healthy Subjects
AstraZeneca
Parexel

Completed

A Study to Assess Safety, Tolerability, PK and PD of AZD2373 in Healthy Male Participants of Sub-Saharan West African Ancestry

Healthy Volunteers

United States
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 1 of 4)

Healthy Volunteers

United States
Nexel Co., Ltd.
Novotech (Australia) Pty Limited

Completed

A Study of NP-011 in Healthy Volunteers

Myocardial Infarction

Australia
Laboratorios Richmond S.A.C.I.F.
FP Clinical Pharma S.R.L.; Syngene International Limited

Completed

A Phase I Study Comparing Pharmacokinetics and Safety of Bevacizumab

Pharmacokinetics | Safety Issues

Argentina
UCB Biopharma SRL

Completed

A Safety and Pharmacokinetics Study of UCB7853 in Healthy Study Participants and Study Participants With Parkinson's Disease (PD)

Parkinson's Disease

Netherlands, United Kingdom
Avilex Pharma

Completed

A Phase 1 Study in Healthy Volunteers to Evaluate the Safety, Tolerability and Pharmacokinetics of AVLX-144

Tolerance | Safety Issues

Finland
University of Liege
Oncomfort; Biowin

Completed

Neurophysiological Correlates of Dissociation Induced by Virtual Reality Hypnosis.

Healthy Volunteers

Belgium
Bloom Science

Completed

A Phase Ia Safety and Tolerability Study of BL-001

Healthy Volunteers

Switzerland
mAbxience Research S.L.

Completed

A Study Comparing the Pharmacokinetic Similarity of MB09 and EU/US-Sourced Xgeva

Healthy Volunteers

Poland
TC Erciyes University
Monitor CRO

Completed

Phase I Study of GN-037 Cream for Psoriasis

Psoriasis

Turkey
Daewoong Pharmaceutical Co. LTD.
Shanghai Haini Pharmaceutical Co., Ltd.

Active, not recruiting

A Clinical Study to Investigate the Mass Balance and Biotransformation of [14C]DWP14012 in Healthy Chinese Male Subjects

Phase 1 Study, Healthy Volunteers

China
RH Nanopharmaceuticals
Center for Bioequivalence Studies and Clinical Research

Completed

Phase 1 Clinical Trial of RHN-001 in Healthy Adult Volunteers

Pharmacokinetics | Tolerability | Safety

Pakistan
Silence Therapeutics plc

Completed

A Phase 1 Study to Evaluate the Safety, Tolerability, PK and PD of SLN124 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Sunshine Lake Pharma Co., Ltd.

Completed

HEC53856 Phase 1 Study - Single and Multiple Oral Dosing in Healthy Volunteers

Healthy

China
Instituto Nacional de Ciencias Medicas y Nutricion...

Withdrawn

Effect of an Polyphenolic Beverage in Healthy Volunteers (PB)

Healthy | Safety Issues
Eisai Inc.

Completed

A Study to Assess Safety, Tolerability, Pharmacokinetics (PK), Immunogenicity, and Pharmacodynamics (PD) of Intravenous Infusions of E2814 in Healthy Participants

Healthy Volunteers

United States
Nuance Pharma (shanghai) Co., Ltd

Completed

A Pharmacokinetic Study of Intravenous NTM-001 in Healthy Chinese Subjects

Healthy Volunteers

China
Pyramid Biosciences

Completed

A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream

Psoriasis | Healthy Volunteers

United States
Dicerna Pharmaceuticals, Inc.
Parexel

Completed

Study of DCR-AUD in Healthy Volunteers

Alcohol Use Disorder (AUD)

United States
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
Phathom Pharmaceuticals, Inc.

Completed

Evaluation of Effect of Vonoprazan on Midazolam Pharmacokinetics in Healthy Participants

Healthy Volunteers

United States
Xencor, Inc.
ICON Clinical Research

Completed

Safety, Tolerability and PK of a Single Subcutaneous Injection of XmAb27564 in Healthy Volunteers

Safety in Healthy Volunteers

United States
Global Antibiotics Research and Development Partnership
Parexel; KCAS

Completed

Zoliflodacin Bioequivalence and Drug-Drug Interaction Study

Healthy Volunteers

Germany
Haisco Pharmaceutical Group Co., Ltd.

Completed

A Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Dosed of HSK36273 in Healthy Volunteers

Healthy

China
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 2 of 4)

Healthy Volunteers
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 3 of 4)

Healthy Volunteers

United States
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 4 of 4)

Healthy Volunteers
Neuronascent, Inc.
National Institute on Aging (NIA)

Completed

Phase1a, Dose-escalation Study of NNI-362 in Healthy Aged Volunteers

Alzheimer Disease

United States
Elysium Health
Duke Clinical Research Institute

Suspended

Biomarker Study to Evaluate Correlations Between Epigenetic Aging and NAD+ Levels in Healthy Volunteers

Epigenetics

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of ABO809 in Healthy Participants

Cryptosporidium Infection, Cryptosporidiosis

United States
Shanghai SIMRD Biotechnology Co., Ltd.

Completed

The Pharmacokinetics (PK), Pharmacodynamics(PD), Safety, Tolerability of SR1375 in Healthy Volunteers

Healthy

China
Apsen Farmaceutica S.A.

Completed

Phase I Study to Evaluate the Safety of Dexibuprofen 200mg Under Fasting and Fed Conditions

Healthy Volunteers

Brazil
Maze Therapeutics

Completed

A Randomized Phase 1 of of MZE001 in Healthy Volunteers

Healthy

United States
Haisco Pharmaceutical Group Co., Ltd.

Completed

Safety, Tolerability and Pharmacokinetics of FTP-198 Tablet in Healthy Chinese Volunteers (FTP-198)

Healthy

China
Eleusis Therapeutics

Completed

A Dose-Ranging Study of 50 µg to 100 µg LSD in Healthy Volunteers

Healthy

United Kingdom
Haisco Pharmaceutical Group Co., Ltd.

Completed

Safety, Tolerability,PK/PD, Food Effect of Single and Multiple Ascending Doses of HSK31858 in Healthy Volunteers

Healthy Volunteers

China
PMV Pharmaceuticals, Inc

Completed

Effect of Food on PC14586 in Healthy Volunteers and the PK of PC14586 in Healthy Japanese Volunteers

Healthy Volunteers

United States
Cugene Inc.

Active, not recruiting

A Phase Ia Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CUG252 in Normal Healthy Volunteers

Systemic Lupus Erythematosus

United States
EnteraSense Limited

Completed

Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -Healthy Volunteers Study

Upper Gastrointestinal Bleeding

Czechia
Cerevance

Completed

Phase 1 SAD/MAD Study of CVN766 in Healthy Volunteers

Tolerance | Safety Issues

Australia

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