Search clinical trials for: adult primary hepatocellular carcinoma

Total 67708 results

Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Sho-Saiko-To Following Removal of Liver Cancer By Embolization in Treating Patients With Liver Cancer That Cannot Be Surgically Removed

Liver Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction

Recurrent Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Bladder Cancer | Stage IV Bladder Cancer | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage... and other conditions

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Vaccine Therapy in Treating Patients With Stage II, Stage IIIA, Stage IIIB, or Stage IVA Liver Cancer

Liver Cancer
University of California, San Francisco
National Cancer Institute (NCI)

Withdrawn

Celecoxib and Erlotinib in Treating Patients With Liver Cancer

Liver Cancer

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Internal Radiation Therapy in Treating Patients With Primary Liver Cancer That Cannot Be Removed by Surgery

Liver Cancer

United States
Swiss Group for Clinical Cancer Research

Completed

Sunitinib in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Liver Cancer

Switzerland
Northwestern University
National Cancer Institute (NCI)

Completed

Epirubicin and Celecoxib in Treating Patients With Hepatocellular Carcinoma

Liver Cancer

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Sorafenib in Treating Patients With Locally Advanced or Metastatic Liver Cancer and Cirrhosis

Liver Cancer

United States
Daiichi Sankyo, Inc.

Completed

DX-8951f in Treating Patients With Liver Cancer

Liver Cancer

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer

Sarcoma | Kidney Cancer | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Melanoma (Skin) | Gastrointestinal Cancer | Liver Cancer | Adrenocortical Carcinoma

United States
Case Comprehensive Cancer Center

Withdrawn

Stereotactic Body Radiation Therapy in Liver Cancer That Cannot be Removed by Surgery or Transplant

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases

Colorectal Cancer | Metastatic Cancer | Liver Cancer | Neuroendocrine Carcinoma | Islet Cell Tumor

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Panobinostat and Sorafenib in Treating Patients With Liver Cancer That is Metastatic and/or Cannot Be Removed by Surgery

Liver Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Chemotherapy in Treating Patients With Unresectable Primary or Metastatic Kidney Cancer

Metastatic Cancer | Liver Cancer
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Octreotide in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Liver Cancer

United States
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Completed

UMCC 003 Cancer-Related Protein Biomarkers in Blood and Tumor Tissue of Patients With Cancer (IRB 2000-294)

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Liver Cancer
Hospices Civils de Lyon

Completed

Iodine I 131 Ethiodized Oil in Preventing Recurrent Cancer in Patients Who Have Undergone Treatment for Liver Cancer

Liver Cancer

France
National Cancer Centre, Singapore

Unknown

Combination Chemotherapy and Interferon Alfa-2b in Treating Patients With Nonmetastatic Liver Cancer That Cannot Be Removed by Surgery

Liver Cancer

Singapore
University College, London

Unknown

Transarterial Chemoembolization Using Doxorubicin Beads With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery

Liver Cancer

United Kingdom
Roswell Park Cancer Institute

Completed

Doxorubicin and Interleukin-2 in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Liver Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Studying Pain and Symptom Distress in Patients With Advanced Colon Cancer, Rectal Cancer, Pancreatic Cancer, or Liver Cancer

Depression | Pain | Fatigue | Colorectal Cancer | Pancreatic Cancer | Liver Cancer

United States
GERCOR - Multidisciplinary Oncology Cooperative...

Unknown

Sorafenib Tosylate in Treating Patients With Liver Cancer That Can Be Removed by Surgery

Liver Cancer

France
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Rebeccamycin Analogue in Treating Patients With Advanced Liver and/or Biliary Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
FeRx

Terminated

Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads Vs. IV Doxorubicin in Treating Liver Cancer

Carcinoma, Hepatocellular

United States, Austria, Thailand, Germany, Ukraine, United Kingdom, Hong Kong, Russian Federation
Myeloid Therapeutics

Recruiting

A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

Hepatocellular Carcinoma

Australia
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
Regeneron Pharmaceuticals

Not yet recruiting

A First-In Human (FIH) Trial to Find Out if REGN10597 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies

Melanoma | Advanced Solid Tumors | Clear-Cell Renal-Cell Carcinoma (ccRCC)
Hunan Cancer Hospital

Recruiting

Cadonilimab in Combination With Lenvatinib and Hepatic Arterial Infusion Chemotherapy (HAIC) for the Treatment of Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
City of Hope Medical Center

Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer (ELUCIDATE)

Hepatocellular Carcinoma | Primary Liver Cancer | Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | Hepatic Cancer | Hepatic Carcinoma | Primary Liver Carcinoma

United States, Japan
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Rituximab Combined With Prior Therapy in Advanced Hepatocellular Carcinoma: Efficacy & Safety Study

Advanced Hepatocellular Carcinoma

China
Pliant Therapeutics, Inc.

Recruiting

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor

United States
Shandong Cancer Hospital and Institute

Recruiting

Radiotherapy Delays Second-line Drug Therapy for Oligo Progressive Primary Liver Cancer

Hepatocellular Carcinoma | Radiotherapy

China
Krystal Biotech, Inc.

Recruiting

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

Metastatic Renal Cell Carcinoma | Metastatic Colorectal Cancer | Lung Cancer Metastatic | Lung Cancer, Non-small Cell | Advanced Cancer | Solid Tumor, Adult | Metastatic Osteosarcoma | Metastatic Sarcoma | Metastatic Hepatocellular Carcinoma | Lung Cancer, Small Cell

United States
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Not yet recruiting

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

Hepatocellular Carcinoma | Liposarcoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Malignant Rhabdoid Tumor | Yolk Sac Tumor | Embryonal Sarcoma of Liver

United States
CNBG-Virogin Biotech (Shanghai) Ltd.

Not yet recruiting

Clinical Study of VG161 Combined With Camrelizumab in Patients With Advanced Primary Hepatocellular Carcinoma

Primary Hepatocellular Carcinoma
Bayer

Recruiting

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery (REFINE-IO)

Unresectable Hepatocellular Carcinoma

Greece, Spain, Brazil, China, Colombia, Italy, Saudi Arabia, Taiwan, Thailand, United States, Korea, Republic of, Argentina, France, Mexico, Turkey
AbbVie

Recruiting

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-2)

Hepatocellular Carcinoma

United States, Taiwan, Spain, France, Italy
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Avutometinib for People With Solid Tumor Cancers

Solid Tumor | Neuroblastoma | Solid Tumor, Adult | Primary Brain Tumor | Solid Carcinoma | Low-grade Glioma | Central Nervous System Tumor | Refractory Cancer | CNS Tumor, Adult | CNS Tumors | NF1 | Plexiform Neurofibroma | CNS Tumor, Childhood | Optic Pathway Gliomas | MAP Kinase Family Gene Mutation

United States
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

Hepatocellular Carcinoma | Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Biliary Tract Cancers | Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer | Head and Neck Squamous-Cell Carcinoma

United States, Israel, Japan, Puerto Rico, Korea, Republic of, Taiwan
Panolos Bioscience

Recruiting

Phase I Study to Evaluate Safety and Anti-tumor Activity of PB101, an Anti-angiogenic Immunomodulating Agent

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Gastric Cancer | Solid Tumor | Advanced Solid Tumor | Solid Tumor, Adult

Korea, Republic of
RenJi Hospital

Not yet recruiting

SALT for Liver Cirrhosis With HCC

Liver Cirrhosis | HCC
Zhejiang Cancer Hospital

Recruiting

Phase II Study of Fruquintinib Combined With Sintilimab and TACE for Inoperable Primary Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Tango Therapeutics, Inc.

Recruiting

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

Cervical Cancer | Breast Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Endometrial Cancer | Solid Tumors, Adult | Carcinoma of Unknown Primary

United States
Tianjin Medical University Cancer Institute and...

Not yet recruiting

H101 Combined With TACE for Primary Hepatocellular Carcinoma With Portal Vein Thrombosis

Portal Vein Thrombosis | Primary Hepatocellular Carcinoma
OncoC4, Inc.
Avance Clinical; OncoC4 AU Pty Ltd

Recruiting

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors (PRESERVE-009)

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Fallopian Tube Cancer | Non Small Cell Lung Cancer | Bile Duct Cancer | Bladder Cancer | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Primary Peritoneal... and other conditions

Australia
AbbVie

Recruiting

Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-1)

Hepatocellular Carcinoma

United States, Japan, Taiwan, Spain, France, Korea, Republic of, Italy
University of Southern California
National Cancer Institute (NCI); Auransa, Inc.

Recruiting

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Advanced Hepatocellular Carcinoma | Metastatic Malignant Neoplasm in the Liver | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Zhujiang Hospital

Recruiting

Applicability of PDOX in Patients With Primary Liver Cancer: A Randomized Controlled Trial

Hepatocellular Carcinoma Resectable

China
Sun Yat-sen University

Not yet recruiting

SBRT Plus Lenvatinib and TACE for Advanced Primary HCC: A Phase 3 Trial (SEARCH) (SEARCH)

Advanced Hepatocellular Carcinoma

China
IRCCS San Raffaele

Recruiting

Liver Embolization Approaches for Tumor Management (LEATUM)

Hepatocellular Carcinoma | Metastatic Cancer | Primary Liver Cancer | Cholangiocarcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer | Metastatic Colon Cancer

Italy

Search clinical trials for: adult primary hepatocellular carcinoma

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