Search clinical trials for: lymphocytes,

Total 2112 results

National Cancer Institute (NCI)

Completed

Hu-Mik-beta1 to Treat T-Cell Large Granular Lymphocytic Leukemia

T-Cell Large Granular Lymphocytic Leukemia | Leukemia, T-Cell Large Granular Lymphocytic

United States
AstraZeneca

Active, not recruiting

A Phase 1 Study of Acalabrutinib in Japanese Adult Patients With Advanced B-cell Malignancies

Part1: Advanced B-cell Malignancies | Part2: r/rCLL and r/rMCL | Part3: Untreated CLL

Japan
University Hospital, Montpellier

Terminated

Characterization of Regulatory T Lymphocytes in the Synovial Fluid of Patients Affected by Rheumatoid Arthritis. (CATERLIS)

Rheumatoid Arthritis | Swelling Joint | Joint Fluid | Characterization of Regulatory T Lymphocytes

France
DERSHENG SUN

Unknown

Lymphocytes Subpopulation in Cancer Patients (CaLym)

Cancer

Korea, Republic of
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United States
Catherine Bollard
Children's National Research Institute

Completed

Multivirus-specific Cytotoxic T Lymphocytes (mCTL)

Refractory Viral Infections

United States
University Hospital, Strasbourg, France

Terminated

Anti-nucleosome B Lymphocytes in Lupus

Systemic Lupus Erythematosus With or Without Clinical Activity

France
University Health Network, Toronto

Withdrawn

Periperal Blood Lymphocytes During Prostate RT

Prostate Cancer
New York Medical College
Johns Hopkins University; Children's Hospital of Philadelphia; Washington University... and other collaborators

Recruiting

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

Primary Immune Deficiency Disorder | Cytomegalovirus Infections

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Patients With Multiple Myeloma That Has Recurred Following Bone Marrow Transplantation

Multiple Myeloma and Plasma Cell Neoplasm

United States
Universitätsklinikum Köln
Hannover Medical School; Miltenyi Biomedicine GmbH; ZKS Köln

Terminated

Viable Human SARS-CoV-2 Specific T Cell Transfer in Patients at Risk for Severe COVID-19 (ACT-COVID-19)

Moderate COVID-19-infection

Germany
Peking University

Not yet recruiting

Phase Ib Clinical Study on the Safety, the Tolerability, the Pharmacokinetics and the Efficacy of ScTIL Injection (Gene Modified Tumor Infiltrating Lymphocytes) Alone and in Combination With B Lymphocyte Adjuvant in the Treatment of Digestive System Malignant Solid Tumors

Digestive System Malignant Solid Tumors
Atara Biotherapeutics

No longer available

Expanded Access Protocol of ATA230 (Third-Party Donor-Derived CMV-CTLs) for the Treatment of CMV Viremia or Disease

CMV Viremia | CMV Disease
Baylor College of Medicine
University of Texas, Southwestern Medical Center at Dallas

Completed

Evaluating the Use of RFT5-dgA to Deplete Alloreactive Cells Prior to Haploidentical Stem Cell Transplantation

Leukemia | Cancer

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

JAK-i on RA B-lymphocytes Tolerance and Disease Resolution Through JAK Signaling In Rheumatoid Arthritis

Rheumatoid Arthritis

Italy
Ain Shams University

Recruiting

TIL Relation to pCR After Neoadjuvant Therapy in Breast Cancer Patients

Breast Cancer

Egypt
Shanghai Juncell Therapeutics
Shanghai 10th People's Hospital

Recruiting

Study on TIL for the Treatment of Advanced Breast Cancer

Breast Cancer | Advanced Breast Cancer | Treatment Side Effects | Effects of Immunotherapy

China
Ankara University

Completed

Haematologic Predictors and Clinical Outcome in Cardiac Surgery

Cardiac Disease
National Institute of Environmental Health Sciences...

Completed

Fluorescence Bronchoscopy and Molecular Characterization of Abnormal Bronchial Lesions: Novel Approaches for Early Detection of Lung Cancer in High Risk Patients

Cancer

United States
Imperial College London
Gene Logic

Completed

Regulation of Inflammatory Mediators in Chronic Obstructive Pulmonary Disease

Emphysema | COPD

United Kingdom
Erasmus Medical Center

Completed

Tacrolimus in CD3+ T Lymphocytes (INTACT)

Immunosuppression

Netherlands
Northwestern University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Lymphocyte-Rich Classical Hodgkin Lymphoma | Recurrent Lymphocyte-Depleted Classical Hodgkin Lymphoma | Recurrent Mixed Cellularity Classical Hodgkin Lymphoma | Recurrent Nodular Sclerosis Classical Hodgkin Lymphoma | Refractory Lymphocyte-Depleted Classical Hodgkin Lymphoma | Refractory Mixed... and other conditions

United States
Sheba Medical Center

Unknown

T-Cell Vaccination in Multiple Sclerosis (MS)

Multiple Sclerosis

Israel
Sheba Medical Center

Unknown

TCV -01-002: T-Cell Vaccination in the Treatment of Probable Multiple Sclerosis

Multiple Sclerosis

Israel
Tufts Medical Center
Immune Control

Completed

Fluphenazine Hydrochloride for Psoriasis (FP-CL2)

Psoriasis

United States
Centre Georges Francois Leclerc

Active, not recruiting

Relevance of T Lymphocytes Tumor Infiltrates CD8 and Foxp3 as Immune Prognostic Biomarker in Breast Cancer Treated by Neo Adjuvant Chemotherapy (PRIMUNEO)

Breast Cancer

France
University of Alabama at Birmingham

Withdrawn

Immunotherapy for Lymphoproliferative Diseases Associated With Epstein-Barr Virus in Patients Who Have Undergone Organ Transplants

Lymphoma | Leukemia

United States
Hospices Civils de Lyon

Completed

Values of the Immune Activation Markers CD38 and HLA-DR and the Ratio CD4/CD8 According to the Delay of Combined AntiRetroviral Therapy (c-ART) Initiation in Primary HIV-infected Patients (PRIMIMMUNO) (PRIMIMMUNO)

HIV-infected Patients

France
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Terminated

Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme (COGLI)

Brain Cancer | Glioblastoma Multiforme | GBM

United States
Eutilex

Recruiting

A Multi-center, Single-arm, Open, Phase I/IIa Clinical Trial to Evaluate the Efficacy and Safety of EBViNT Cell (EBV Specific Autologous CD8+ T Cell) in Patients With Treatment Failed Epstein Barr Virus (EBV)-Positive Malignancies

EBV Associated Extranodal NK/T-cell Lymphoma | EBV-Associated GastricCarcinoma or Esophageal AdenoCarcinoma

Korea, Republic of
The Catholic University of Korea

Unknown

Combined Effect of Natural Killer Cell and Doublet Chemotherapy in Advanced NSCLC as the 1st Line Treatment (ANKL-2)

Non-small Cell Lung Cancer

Korea, Republic of
University of Alabama at Birmingham
Miltenyi Biotec, Inc.

Active, not recruiting

Standardization of CD3+ T Cell Dose for Patients Receiving Allogeneic Peripheral Blood Stem Cell Transplantation From Matched Related Donors

Hematopoietic Stem Cell Transplantation

United States
Poitiers University Hospital

Active, not recruiting

Innate T Cells and TKI Discontinuation (TIBIOP-LMC)

Chronic Myeloid Leukemia

France
Assistance Publique - Hôpitaux de Paris
Pierre and Marie Curie University; Paris 12 Val de Marne University

Completed

Suicide Gene Therapy for Donor Lymphocytes Infusion After Allogeneic Hematopoietic Stem Cell Transplantation (ILD-TK01)

Hematological Malignancy

France
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Completed

MRD-directed Donor Lymphocyte Infusion for Reduce of Relapse After Allo-HSCT

Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Relapse | Donor Lymphocyte Infusion

China
Masonic Cancer Center, University of Minnesota

Completed

Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia

AML | MDS | Leukemia, Lymphocytic, Acute | Leukemia, Myeloid, Chronic

United States
Wake Forest University Health Sciences

Terminated

T-cell Depleted Alternative Donor Transplantation

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Immune Deficiency | Lymphomas | Bone Marrow Failure | Osteopetrosis | Hemoglobinopathy

United States
University of Liege
KU Leuven; Maastricht University Medical Center; University Hospital, Ghent; Queen... and other collaborators

Recruiting

Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function

Graft-versus-host Disease | Poor Graft Function | Low Donor T-cell Chimerism

Belgium, Netherlands
Catherine Bollard

Active, not recruiting

Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)

CMV | EBV | Adenovirus

United States
University Hospital, Basel, Switzerland
University of Bonn

Completed

mRNA Expression in Lymphocytes of Glaucoma Patients

Glaucoma | Healthy Subjects

Switzerland
Fujian Medical University

Not yet recruiting

Study Evaluating Neoadjuvant Immunotherapy Increasing CD8+ Cell Infiltration in Advance Gastric Adenocarcinoma

Advanced Gastric Carcinoma | Neoadjuvant Immunotherapy | CD8+ Tumor Infiltrating Lymphocytes
Shiraz University of Medical Sciences
Mashhad University of Medical Sciences

Completed

Effect of Weight Reduction on Immunity

Weight Loss | Immunity | Lymphocytes | Viral Diseases | Anti-obesity Agents
Second Affiliated Hospital, School of Medicine,...
First People's Hospital of Hangzhou

Recruiting

Comparison of PD1+T Cell Expression in Peripheral Blood for Cardiac Function Prognosis in Patients With Acute MI

Acute Myocardial Infarction | PD1

China
National Center for Tumor Diseases, Heidelberg
German Cancer Research Center; University Hospital Heidelberg

Terminated

Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of Advanced Colorectal Cancer (ATACC)

Colorectal Carcinoma

Germany
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Chronic Lymphocytic Leukemia | Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia and other conditions

United States
Fundación Pública Andaluza para la gestión de la...

Recruiting

Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib (Treg4GVHD)

Chronic Graft vs Host Disease

Spain
H. Lee Moffitt Cancer Center and Research Institute
Florida Department of Health

Recruiting

Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT

Acute Myeloid Leukemia

United States
Fundación Pública Andaluza para la gestión de la...

Completed

Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-host-Disease (GVHD-TReG)

Chronic Graft vs Host Disease

Spain
Peking University People's Hospital

Unknown

Chemotherapy and DLI for Prevention of Second Relapse in Patients With Relapsed Acute Leukemia After Allotransplant

Acute Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Relapse | Donor Lymphocyte Infusion | Graft-versus-host Disease

China
University of Zurich

Completed

Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma

Switzerland

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