Search clinical trials for: molecular response

Total 107898 results

Emory University

Recruiting

Systems Biological Assessment of Statin Effect on Vaccine Responses

Vaccine Response

United States
Hangzhou Highlightll Pharmaceutical Co., Ltd

Recruiting

A Phase 3 Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDs (TARA)

Rheumatoid Arthritis

China
Jip Groen
InBiome

Recruiting

Molecular Culture for the Diagnosis of Pediatric Sepsis (CHAMPIONS)

Sepsis | Microbial Colonization | Infection, Bacterial | Antibiotic Side Effect | Sepsis Bacterial | Sepsis, Neonatal

Netherlands
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia (RESTORE)

Hypophosphatasia
National Cancer Institute, Egypt

Recruiting

Low Dose Versus High Dose Methylene Blue in Septic Patients

Septic Shock

Egypt
Wuhan Union Hospital, China

Recruiting

68Ga-FAPI-04 PET Imaging in Early Response Evaluation of Rectal Cancer Patients Treated With Immunotherapy

Rectal Cancer

China
Chinese Medical Association

Recruiting

Elevated Initial APRI Value Was Associated With SALD

Liver Dysfunction | Sepsis-associated Liver Dysfunction

China
Cees Tack

Not yet recruiting

Role of Adrenaline in in the Inflammatory Response in Diabetes (RAID)

Hypoglycemia | Diabetes type1 | Inflammatory Response

Netherlands
Jun Guo

Not yet recruiting

Fluzoparib in Combination With Camrelizumab and Temozolomide in Advanced Melanoma

Melanoma
Shandong University
Shandong Provincial Hospital; Qianfoshan Hospital; Jining Medical University; Yantai... and other collaborators

Recruiting

Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis. (PIP/TAZO)

Late-Onset Neonatal Sepsis

China
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Malaria Infection

Kenya, Burkina Faso, Gambia, Zambia
University Hospital, Basel, Switzerland

Recruiting

Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects (LBL)

Healthy

Switzerland
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

HYPEROXIA Responses and ROS

Cerebrovascular Disorders

United States
Federal University of São Paulo

Not yet recruiting

Use of Dobutamine in Patients With Sepsis and Maintained Hypoperfusion After Initial Volemic Resuscitation. (DEEP)

Sepsis | Hypoperfusion | Hyperlactatemia

Brazil
Minia University

Recruiting

Effect of Atorvastatin as a Renal Protection in Patients With Systemic Inflammatory Response Syndrome Using Renal Arterial Resistive Index

Renal Protection

Egypt
Indonesia University

Recruiting

Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group

Acute Kidney Injury Due to Sepsis

Indonesia
Menoufia University

Recruiting

Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy

Dexmedetomidine | Laparoscopic Cholecystectomy | Propofol | Lidocaine | Hemodynamic Responses

Egypt
Rambam Health Care Campus

Recruiting

Evaluating Bronchodilator Response in Patients With Bronchiectasis

Bronchiectasis | Cystic Fibrosis | Bronchiolitis Obliterans | Primary Ciliary Dyskinesia | Primary Immune Deficiency

Israel
Odense University Hospital

Recruiting

Early Initiated Vasopressor Therapy in the Emergency Department (VASOSHOCK)

Shock | Shock, Septic | Hypotension | Hypovolemia | Hypotension and Shock | Hypovolemic Shock | Hypotension Symptomatic | Hypovolemic

Denmark
National Institute of Allergy and Infectious Diseases...

Recruiting

Effect of Bismuth Subsalicylate on the Gut Microbiome and Host Response in Healthy Adults

Healthy Adults

United States
Rambam Health Care Campus
Assaf-Harofeh Medical Center; Sheba Medical Center; Monaldi Hospital; Rutgers Robert... and other collaborators

Not yet recruiting

Cefiderocol and Ampicillin-sulbactam vs. Colistin +/- Meropenem for Carbapenem Resistant A. Baumannii (CASCADE)

Carbapenem Resistant Bacterial Infection | Acinetobacter Bacteremia | Acinetobacter Pneumonia
Tehran University of Medical Sciences

Not yet recruiting

Comparison of the Clinical Response of Total Neoadjuvant Treatment of Two Methods of Long-term or Short-term Chemoradiotherapy in Rectal Cancer (TEHRAN)

Locally Advanced Rectal Carcinoma
Henan Cancer Hospital

Recruiting

Comparing the Efficacy of Nab-PH+Pyrrolitinib and TCbHP in the Neoadjuvant Treatment of HER2 Positive BC

Breast Cancer | HER2-positive Breast Cancer

China
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Weight Loss Study: Genetics and Response to Naltrexone/Bupropion

Obesity

United States
Radboud University Medical Center

Recruiting

Multi-Omics to Predict the Blood Pressure Response to Antihypertensives (HT-PREDICT)

Primary Hypertension

Netherlands
Vall d'Hebron Institute of Oncology

Recruiting

Predictive Biomarkers of Response to Checkpoint Inhibitors in Triple Negative Breast Cancer: a Multiomics Platform (PORTRAIT)

Triple Negative Breast Cancer

Spain
Yale University
National Institute of Mental Health (NIMH)

Recruiting

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Bipolar Disorder | Depressive Disorder, Major | Post Traumatic Stress Disorder

United States
Institut Català d'Oncologia
Fundación Sociedad Española de Oncologia Médica; Instituto de Salud Carlos III and other collaborators

Recruiting

Early On-treatment Transcriptional Profiling as Predictor of Response in Early-stage HER2-positive Breast Cancer (BiOnHER)

Neoplasms | Breast Cancer | HER2-positive Breast Cancer

Spain
National Cancer Institute (NCI)

Recruiting

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

Neoplasms | Esophageal Neoplasms | Esophagus Cancer | Esophagus Neoplasm | Neoplasms, Esophageal | Esophageal Cancer (EsC)

United States
Mclean Hospital
United States Department of Defense; NorthShore University HealthSystem

Recruiting

Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrhea

Dysmenorrhea | Menstrual Pain | Non-steroidal Anti-inflammatory Drug

United States
Christian Hassager

Recruiting

The Danish Out-of-Hospital Cardiac Arrest Study (DANOHCA)

Out-Of-Hospital Cardiac Arrest | Post-Cardiac Arrest Syndrome

Denmark
Jinnah Postgraduate Medical Centre

Recruiting

Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality (MUNI-SEP)

Septic Shock | Severe Sepsis | MODS

Pakistan
The First Affiliated Hospital of Guangzhou Medical...
Guangdong Provincial Hospital of Traditional Chinese Medicine; Tongji Hospital and other collaborators

Not yet recruiting

Biomarkers for Predicting the Response to Inhaled Corticosteroid in Patients With Chronic Cough. (CC-ICS)

Cough

China
Merz Therapeutics GmbH
Heinrich-Heine University, Duesseldorf

Recruiting

Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia (RELY-CD)

Cervical Dystonia

Germany
M.D. Anderson Cancer Center
SpringWorks Therapeutics, Inc.

Not yet recruiting

Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical Study

Tumor

United States
University of Oxford

Recruiting

KLH Challenge to Explore the Human Immune Response

Immune Response

United Kingdom
Centre Hospitalier St Anne

Not yet recruiting

Prediction of the Therapeutic Response in Depression Based on Neuro-computational Modeling Assessment of Motivation (STRATIDEP)

Major Depressive Disorder

France
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
University of California, San Francisco

Recruiting

Molecular Signatures of Cutaneous Dupilumab Response

Atopic Dermatitis

United States
RenJi Hospital

Not yet recruiting

Attenuation of the Hemodynamic Response to Double-lumen Endotracheal Intubation With Nebulized Lidocaine

Lung Neoplasms
University Hospital "Sestre Milosrdnice"

Not yet recruiting

Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery

Postoperative Pain | Cesarean Section | Wound Heal
Tunis University

Recruiting

Early Administration of Norepinephrine in Sepsis (EA-NE-TUN)

Sepsis, Severe

Tunisia
Alejandro Rodriguez Oviedo , MD
BioMérieux; Biocartis

Recruiting

Molecular Early Sepsis Identification Study (MESIS)

Sepsis | Molecular Diagnosis

Spain
Alexandria University

Recruiting

Correlation of Genetic Variations With Clinical Response in Substance Use Disorder

Substance Use Disorders | Substance Dependence

Egypt
Massachusetts General Hospital

Recruiting

Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms

Normal Physiology

United States
University of New Mexico
La Jolla Pharmaceutical Company

Recruiting

Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock (DARK-Sepsis)

Septic Shock | Vasodilatory Shock

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Early Stage Triple-Negative Breast Carcinoma

United States, Puerto Rico
Ain Shams University

Recruiting

Efficacy and Safety of Continuous Versus Intermittent Linezolid Infusion in Critically Ill Patients With Septic Shock

Treatment Efficacy

Egypt
Beth Israel Deaconess Medical Center

Not yet recruiting

Define Predictors of Response to Ozanimod in UC Discovering Biomarkers in the Management of Ulcerative Colitis

Ulcerative Colitis

United States
Ain Shams University

Recruiting

Alpha-Lipoic Acid in Patients With Sepsis

Sepsis

Egypt

Search clinical trials for: molecular response

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