Search clinical trials for: 4-group clinical interventional study

Total 156925 results

ICN Pharmaceuticals

Terminated

The Safety and Effectiveness of Ribavirin in the Early Stages of HIV-Infection

HIV Infections
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Ganciclovir Plus Interferon Beta in Preventing the Return of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Hoffmann-La Roche

Completed

A Comparison of Saquinavir Hard- and Soft-Gelatin Capsules in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Adding PMPA Prodrug to an Anti-HIV Drug Combination to Treat HIV-Infected Patients

HIV Infections

United States
Gilead Sciences
Glaxo Wellcome; Dupont Applied Biosciences

Completed

Safety and Effectiveness of Giving Adefovir Dipivoxil Plus Abacavir Plus Efavirenz Plus Amprenavir to HIV-Infected Patients Who Have Failed to Respond to Previous Protease Inhibitor Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Taken AZT

HIV Infections

United States, Canada, Puerto Rico
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Phase I Study of the Third Generation Adenovirus H5.001CBCFTR in Patients With Cystic Fibrosis

Cystic Fibrosis
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Gonadotropin-Releasing Hormone Pulse Frequency in Sexual Maturation and in the Menstrual Cycle

Precocious Puberty | Hypogonadism

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Study of Genotype and Phenotype Expression in Congenital Nephrogenic Diabetes Insipidus

Diabetes Insipidus, Nephrogenic
Eunice Kennedy Shriver National Institute of Child...
Baylor College of Medicine

Completed

Study of Cardiac and Paroxysmal Abnormalities in Rett Syndrome

Rett Syndrome
National Center for Research Resources (NCRR)
Shirley Ryan AbilityLab

Completed

Pilot Study of Fructose for Sickle Cell Crisis

Sickle Cell Anemia
National Institute of Neurological Disorders and...
University of Colorado, Denver

Unknown

Randomized Study of Fetal Neurotransplantation for the Treatment of Parkinson's Disease

Parkinson Disease
Steinhart Medical Associates

Unknown

Treatment of Advanced AIDS Patients With Dextrin Sulfate

HIV Infections

United States
Merck Sharp & Dohme LLC

Unknown

The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment

HIV Infections

United States
National Center for Research Resources (NCRR)
Children's Hospital Medical Center, Cincinnati

Completed

Diagnostic Study of Adrenal Cortical Function in Children With Septic Shock

Septic Shock

United States
National Center for Research Resources (NCRR)
Columbia University

Completed

Genetic Study of Familial Epilepsy

Epilepsy

United States
Hoffmann-La Roche

Unknown

Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection

HIV Infections | Cytomegalovirus Retinitis

United States, Puerto Rico
Hoffmann-La Roche
Trimeris

Completed

T-20 in HIV Patients With Prior Drug Treatment and/or Resistance to Each of the Three Classes of Anti-HIV Drugs

HIV Infections

Switzerland, Spain, United Kingdom, Germany, Belgium, Australia, Sweden, Italy, Netherlands
Abgenix

Completed

A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD

Pulmonary Disease, Chronic Obstructive | Bronchitis, Chronic

United States
U.S. Bioscience

Completed

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate With Leucovorin Protection for Patients With Pneumocystis Carinii Pneumonia.

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Energy Requirements in Critically Ill Newborns

Respiratory Distress Syndrome

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Study of Pituitary Size and Function in Familial Dwarfism of Sindh

Growth Hormone Deficiency
Eunice Kennedy Shriver National Institute of Child...
Children's National Research Institute

Terminated

Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease
National Center for Research Resources (NCRR)
Scripps Clinic

Completed

Phase II Pilot Study of Cladribine (2-Chlorodeoxyadenosine; 2-CdA) for Early Stage Primary Sclerosing Cholangitis

Cholangitis, Sclerosing
Hoffmann-La Roche

Completed

Treatment of Psoriasis Using Acitretin in HIV-Positive Patients

HIV Infections | Psoriasis

United States
Merck Sharp & Dohme LLC

Unknown

Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

HIV Infections

United States
Shaman Pharmaceuticals

Completed

SP-303T Applied to the Skin of Patients With Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success With Acyclovir

HIV Infections | Herpes Simplex

United States
Schering-Plough

Completed

Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients

HIV Infections | Candidiasis, Oral

United States, Barbados
Liposome

Completed

Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States
Novartis

Completed

Safety and Effectiveness of Giving Lamisil to HIV-Positive Subjects With Thrush Who Have Not Responded to Fluconazole Treatment

HIV Infections | Candidiasis, Oral

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Phase II Pilot Study of Aminoimidazole Carboxamide Riboside (AICAR), a Precursor of Purine Synthesis, for Lesch-Nyhan Disease

Lesch-Nyhan Syndrome
National Center for Research Resources (NCRR)
Medical University of South Carolina

Completed

Genetic Study of Sitosterolemia

Lipid Metabolism, Inborn Errors | Sitosterolemia

United States
Jacobus Pharmaceutical

Completed

A Comparison of Dapsone and Trimethoprim-Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Boehringer Ingelheim

Completed

A Multi-Center, Placebo-Controlled, Double-Blind, Randomized Trial Comparing the Virologic and Immunologic Activities of 400 Mg Nevirapine in Combination With Zidovudine Versus Zidovudine Alone in Asymptomatic HIV-1 Infected Patients With 4-12 Months of Prior Zidovudine Therapy and 200-500 CD4+ Cell

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States, Canada, Puerto Rico
National Center for Research Resources (NCRR)
University of Michigan

Completed

Study of Zinc for Wilson Disease

Wilson Disease

United States
Murphy, Michael P., MD
Indiana University School of Medicine

Unknown

Safety Study of Using Stem Cells to Stimulate Development of New Blood Vessels in Peripheral Vascular Disease

Peripheral Vascular Diseases

United States
PharmaResearch

Unknown

Comparing Side Effects of Two Forms of Videx in HIV-Infected Adults

HIV Infections

United States
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs

HIV Infections

United States
Glaxo Wellcome

Completed

A Dose-Frequency Trial of Oral Retrovir in Patients With AIDS or Severe ARC

HIV Infections

United States
Pharmacia and Upjohn

Completed

Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected Patients

HIV Infections

United States
Univax Biologics Inc

Completed

A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS Patients

HIV Infections | Cryptosporidiosis

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Unknown

Study of Treatment and Metabolism in Patients With Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors

United States
National Center for Research Resources (NCRR)
University of Texas

Unknown

Randomized Study of Testosterone and Progressive Resistance Exercise in Men With Burn Injury

Burns

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of Porphyria

Porphyria
National Institute on Drug Abuse (NIDA)
Johns Hopkins University

Unknown

Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Injection Drug Users

Tuberculosis
Eunice Kennedy Shriver National Institute of Child...
University of Washington

Unknown

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Wiskott-Aldrich Syndrome | Leukocyte Adhesion Deficiency Syndrome | X-Linked Agammaglobulinemia | X-Linked Hyper IgM Syndrome

United States
National Center for Research Resources (NCRR)
Stanford University

Unknown

Phase II Randomized Study of Intravenous Versus Oral Clomipramine in Patients With Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Different Dose Levels of 1263W94 in the Treatment of Cytomegalovirus (CMV) of the Eyes in HIV-Infected Patients

HIV Infections | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
Children's Hospital Colorado

Unknown

Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis

Liver Cirrhosis | Cirrhosis

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