Search clinical trials for: AMG 423

Total 1951 results

Amgen

Terminated

A Phase 1 Dose Escalation Study of AMG 780 in Adult Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States
Amgen

Withdrawn

Evaluate Time Associated With the Preparation & Administration of Denosumab/Pamidronate in Patients With Solid Tumors and Metastatic Bone Disease

Solid Tumor | Metastatic Bone Disease
Amgen

Completed

A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 403 in Healthy Subject

Chronic Pain
Foundation for the National Institutes of Health
M.D. Anderson Cancer Center; Eli Lilly and Company; National Institute of Diabetes... and other collaborators

Unknown

A Prospective Observational Study to Evaluate Acute Kidney Injury Biomarkers In Patients Receiving First Cycle of Cisplatin Chemotherapy for Head and Neck Cancers

Head and Neck Cancer

United States
Amgen Research (Munich) GmbH

Completed

Phase II Study of the BiTE® Blinatumomab (MT103) in Patients With Minimal Residual Disease of B-precursor Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia

Germany
Amgen Research (Munich) GmbH

Completed

Safety Study of the Bispecific T-cell Engager Blinatumomab (MT103) in Patients With Relapsed NHL

Non-Hodgkin's Lymphoma, Relapsed

Germany
Amgen Research (Munich) GmbH

Completed

Phase I Study of MT110 in Lung Cancer (Adenocarcinoma and Small Cell), Gastric Cancer or Adenocarcinoma of the Gastro-Esophageal Junction, Colorectal Cancer, Breast Cancer, Hormone-Refractory Prostate Cancer, and Ovarian Cancer (MT110-101)

Solid Tumors

Germany
CONKO-Studiengruppe
Eli Lilly and Company; Sanofi; Amgen

Completed

Chemotherapy With or Without Enoxaparin in Pancreatic Cancer (PROSPECT)

Pancreatic Cancer

Germany
Amgen

Terminated

Nplate® Pregnancy Exposure Registry (NPER)

Low Birth Weight | Birth Defect | Spontaneous Abortions
Bayer
Amgen

Completed

Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction

Erectile Dysfunction

Russian Federation
Emory University
Amgen

Completed

Etanercept and Vascular Function in Psoriasis (EVIP)

PSORIASIS

United States
Bayer
Amgen

Completed

Study of Nexavar (Sorafenib, BAY 43-9006) in Patients With Advanced Refractory Cancer

Carcinoma, Renal Cell

United States, United Kingdom
Amgen

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 403 in Subjects With Osteoarthritis Knee Pain

Osteoarthritis
Amgen

Completed

A Phase 1 Study of AMG 208 in Subjects With Advanced Solid Tumors

Cancer | Advanced Solid Tumors | Oncology | Tumors | Advanced Malignancy | Oncology Patients

United States
Bayer
Amgen

Completed

Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) Subjects

Metastatic Colorectal Cancer

Belgium, Italy, Poland, Spain, Russian Federation, United States, Hungary, Romania, United Kingdom, Ukraine
The Hong Kong Polytechnic University

Completed

Efficacy of JUC as Hand Rub Evaluated by Using European Standard 1500 (JUC)

Infectious Disease Transmission

Hong Kong
Foundation for the National Institutes of Health
M.D. Anderson Cancer Center; Eli Lilly and Company; National Institute of Diabetes... and other collaborators

Unknown

Prospective Observational Study to Evaluate Biomarkers of Aminoglycoside Nephrotoxicity in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
Amgen

Completed

Single-Ascending Dose Study of AMG 333 in Healthy Subjects and Subjects With Migraines

Migraine

United States
University of Alabama at Birmingham
Amgen; Sanofi-Synthelabo

Completed

Study of Sequential Topoisomerase, Irinotecan/Oxaliplatin - Etoposide /Carboplatin in Extensive Small Cell Lung Cancer (SCLC)

Non-Small Cell Lung Cancer

United States
Herbert Hurwitz, MD
Novartis; Genentech, Inc.; Amgen

Completed

BEP Study Phase I (Bevacizumab, Everolimus, Panitumumab) (BEP)

Solid Tumors

United States
Amgen

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 811 in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Amgen

Completed

Study to Evaluate the Concentration of Denosumab in Seminal Fluid in Healthy Men After a Single Subcutaneous Dose

Healthy Volunteer

United States
University of Utah
Amgen; Eisai Inc.

Completed

KRAS Wild-type Metastatic Colorectal Cancer Trial

Colorectal Cancer

United States
Bayer
Amgen

Completed

A Treatment Combination for Patients With Unresectable Stage III or Stage IV Melanoma

Melanoma

United States, Canada, Germany, France, United Kingdom, Australia, Netherlands
Swedish Orphan Biovitrum
Amgen

Completed

Pharmacokinetic Study of Palifermin in Subjects Receiving Radiation Therapy and Chemotherapy Followed by Blood Stem Cell Support

Lymphoma | Leukemia | Myeloma
Amgen

Terminated

20110165: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms (Study 165)

Schizophrenia

United States, France, United Kingdom, Malaysia, Poland, Czech Republic
Nordic Lymphoma Group
Amgen

Completed

Dose Dense Chemotherapy and Rituximab for Young High Risk Diffuse Large B-Cell Lymphoma Patients (CRY-04) (CRY-04)

Diffuse Large B-Cell Lymphoma

Norway, Denmark, Finland, Sweden
Amgen

Completed

AMG 386 Drug-Drug Interaction Study With Paclitaxel

Advanced Solid Tumors

United States
Amgen

Terminated

Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus

Systemic Lupus Erythematosus | Cutaneous Lupus | Lupus | Discoid Lupus

United States
Amgen

Completed

Safety Study of AMG 811 in Subjects With Systemic Lupus Erythematosus With and Without Glomerulonephritis

Systemic Lupus Erythematosus | Nephritis

United States, Hong Kong, France, Malaysia, Mexico
Swedish Orphan Biovitrum
Amgen

Completed

Palifermin for the Reduction of Oral Mucositis in Single-dose Evaluation (PROMISE)

Lymphoma | Leukemia | Cancer
Swedish Orphan Biovitrum
Amgen

Completed

Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation

Hematologic Malignancies | Graft Versus Host Disease
Kyowa Kirin Co., Ltd.

Completed

Safety Study of AMG 531 in Japanese Subjects With ITP

Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Neal Ready
Amgen

Terminated

Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN (TOP0901)

Squamous Cell Carcinoma of the Head and Neck

United States
Amgen

Terminated

Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas

Adenocarcinoma of the Pancreas | Locally Advanced | Unresectable

Spain, Belgium, Denmark, Poland, United States, Korea, Republic of, Russian Federation, Austria, Portugal, United Kingdom, Germany, Hungary, Czech Republic
Amgen

Completed

European Union Registry in Paediatric Chronic Kidney Disease Patients Looking at Safety and Usage Patterns of Darbepoetin Alfa

Chronic Kidney Disease
Duke University
National Institute of Mental Health (NIMH)

Completed

Treatment of Obsessive Compulsive Disorder in Children

Obsessive-Compulsive Disorder

United States
Amgen

Completed

LEARN-6™: A Prospective, Observational Nursing Home Study

Anemia | Chronic Kidney Disease
Amgen

Completed

A Multicenter, Randomized Placebo Controlled Pilot MicroCT Study to Estimate the Effect of Treatment With Denosumab (AMG 162) and Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density

Postmenopausal Osteoporosis
Amgen

Completed

Safety and Efficacy Study of Romiplostim (AMG 531) to Treat ITP in Pediatric Subjects

Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Pediatric Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Amgen
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Canadian Assessment of Patient Outcomes and Effectiveness of Etanercept (Enbrel) in Psoriasis

Psoriasis
Innovaderm Research Inc.
Amgen

Completed

Exploratory Study on Quality of Life in Patient With Moderate Psoriasis and Moderate Psoriatic Arthritis

Psoriasis | Psoriatic Arthritis

Canada
Innovaderm Research Inc.
Amgen

Completed

Safety and Efficacy of Etanercept in Patients With Psoriasis Who Failed to Respond to Other Biologic Treatments

Psoriasis

Canada
Amgen

Completed

Moderate to Severe Plaque Psoriasis With Scalp Involvement

Psoriasis
Amgen
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

CAMEO: Canadian Methotrexate and Etanercept Outcome Study

Rheumatoid Arthritis

Canada
Amgen

Completed

ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis

Cardiovascular Disease | Hyperparathyroidism | End Stage Renal Disease | Chronic Kidney Disease | Secondary Hyperparathyroidism | Chronic Renal Failure | Coronary Artery Calcification | Vascular Calcification | Kidney Disease | Calcification | Nephrology
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Xenin-25: Novel Regulator of Insulin Secretion and Beta-cell Function

Type 2 Diabetes Mellitus

United States
Amgen

Completed

Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease (BONAFIDE)

Secondary Hyperparathyroidism

United States, Italy, Belgium, Switzerland, Hungary, Spain, Turkey, Poland, Portugal, United Kingdom, Czech Republic, Macedonia, The Former Yugoslav Republic of
University of Alabama at Birmingham
Pfizer; Amgen; Barr Laboratories

Completed

Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) (TEAR)

Rheumatoid Arthritis

United States
Astellas Pharma Inc

Completed

A Phase 3 Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia Not on Dialysis

Renal Insufficiency | Chronic Kidney Disease | Hyperphosphatemia

Japan

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