Clinical Trials Sponsored by IO Biotech

Total 1809 results

China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Zhejiang Provincial Center...

Recruiting

Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in People With HIV Infected

HIV Infections | COVID-19

China
University of Florida
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency: (DCA/PDCD)

Pyruvate Dehydrogenase Complex Deficiency

United States
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Jiangsu Province Center for...

Active, not recruiting

A Trial to Evaluate the Lot-to-lot Consistency of Live Attenuated Varicella Vaccine in Healthy People 1-12 Years of Age

Varicella

China
China National Biotec Group Company Limited
Wuhan Institute of Biological Products Co., Ltd; Hubei Provincial Center for...

Recruiting

Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in People Aged ≥18 Years With HIV Infected

HIV Infections | COVID-19

China
China Agricultural University
General Hospital of Chinese Armed Police Forces; Beijing Anzhen Hospital; Peking... and other collaborators

Completed

Effects of Probiotics on the Patients With End Stage Renal Disease (ESRD)

Kidney Failure, Chronic

China
China National Biotec Group Company Limited
Peking University; Beijing Institute of Biological Products Co Ltd.; Beijing...

Completed

Immunogenicity and Safety of Sabin-IPV Replacement Vaccination

Vaccination

China
Tangent Data
Stanley Medical Research Institute; MediStat Ltd.; PCI pharma services (formerly... and other collaborators

Unknown

Estradiol as add-on to Antipsychotics (EST-S-02)

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorders

Moldova, Republic of
First Affiliated Hospital of Fujian Medical University
Third Affiliated Hospital, Sun Yat-Sen University; MyBiotech Co. Ltd, China

Completed

An Diagnostic Cohort on AQP4-Immunoglobulin G Detection Kit

Neuromyelitis Optica Spectrum Disorders

China
Tokai University
Abbott Medical Devices; Kaneka Medical America LLC; Terumo Medical Corporation; Asahi Intech and other collaborators

Completed

Guidewire for Chronic Total Occlusion (G-FORCE)

Coronary Occlusion

Japan
Centre hospitalier de l'Université de Montréal...
Maisonneuve-Rosemont Hospital; Centre de Recherche du Centre Hospitalier de... and other collaborators

Completed

IMPACT-CABG Trial: IMPlantation of Autologous CD133+ sTem Cells in Patients Undergoing CABG (IMPACT-CABG)

Myocardial Infarct | Heart Failure

Canada
City of Hope Medical Center
CSL Behring; Grifols Therapeutics LLC; Grifols Biologicals, LLC; Charta Foundation and other collaborators

Withdrawn

Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive (RESIST NAIVE)

Severe Hemophilia A
Bharat Biotech International Limited
Indian Council of Medical Research; National Institutes of Health (NIH); Stanford... and other collaborators

Completed

Dose Escalation Study to Evaluate Oral Rotavirus Vaccine 116E Live Attenuated in Healthy Infants 8 to 20 Weeks Old

Diarrhea

India
City of Hope Medical Center
CSL Behring; Grifols Therapeutics LLC; Grifols Biologicals, LLC; Charta Foundation and other collaborators

Completed

Rescue Immunotolerance Study in Induction of Immune Tolerance (ITI)-Experienced Patients (RES.I.S.T. Experienced) (RESIST EXP)

Severe Hemophilia A

United States
Peking University First Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.; Beijing Biote Pharmaceutical Co.,Ltd

Recruiting

Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma

Salivary Gland Neoplasm Duct

China
AIDS Clinical Trials Group
Bristol-Myers Squibb; National Institute of Allergy and Infectious Diseases... and other collaborators

Completed

Comparative Study of Three NNRTI-Sparing HAART Regimens

HIV Infection

United States, Puerto Rico
Baylor College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Terminated

Newly Designed Vaginal Stent to Improve Patient Comfort and Healing Following Vaginal Surgery or Vaginal Radiation

Vaginal Stricture

United States
AB Biotics, SA
Hospital General Dr. Manuel Gea González; Innovacion y Desarrollo de Estrategias... and other collaborators

Completed

Efficacy of L. Plantarum and P. Acidilactici in Adults With SARS-CoV-2 and COVID-19

SARS-CoV Infection

Mexico
China National Biotec Group Company Limited
The University of Hong Kong; Beijing Institute of Biological Products Co Ltd.; Wuhan Institute of Biological Products Co., Ltd

Active, not recruiting

Sequential Immunization of Two Doses of Inactivated COVID-19 Vaccine (Omicron) in Vaccinated Population Aged 18 Years and Above (COVID-19)

COVID-19

Hong Kong
China Agricultural University
General Hospital of Chinese Armed Police Forces; Peking University Shougang... and other collaborators

Completed

The Correlation Between Gut Microbiome/Metabolite and End Stage Renal Disease (ESRD)

Kidney Failure, Chronic

China
Xiamen University
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise... and other collaborators

Completed

Clinical Trial of Recombinant Hepatitis E Vaccine

Hepatitis E

China
Rigen Biotech
RenJi Hospital; Tianjin Medical University Cancer Institute and Hospital; Guangdong... and other collaborators

Recruiting

NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules

Thyroid Cancer | Thyroid Nodule

China
National Vaccine and Serum Institute, China
China National Biotec Group Company Limited; Beijing Institute of Biological... and other collaborators

Recruiting

Recombinant COVID-19 Vaccine (CHO Cell, NVSI-06-09) Phase III Clinical Trial

Coronavirus Infections | COVID-19

United Arab Emirates
National Vaccine and Serum Institute, China
China National Biotec Group Company Limited; Beijing Institute of Biological... and other collaborators

Recruiting

A Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cell, NVSI-06-09) and Inactivated COVID-19 Vaccine (Vero Cell)

COVID-19

United Arab Emirates
John Lister
Miltenyi Biotec, Inc.; Lentigen Technology, Inc.; AHN (Allegheny Health Network)...

Recruiting

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Diffuse Large B Cell Lymphoma | B Acute Lymphoblastic Leukemia | B-Cell Lymphoma | Transformed Lymphoma

United States
National Vaccine and Serum Institute, China
China National Biotec Group Company Limited; Lanzhou Institute of Biological... and other collaborators

Recruiting

Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above

Coronavirus Infections | COVID-19 Pneumonia

United Arab Emirates
PATH
International Centre for Diarrhoeal Disease Research, Bangladesh; The Emmes... and other collaborators

Completed

Phase 3 Trial of a Bivalent HPV Vaccine (Cecolin®) in Young Girls

Cervical Cancer

Bangladesh, Ghana
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Wuhan Institute of Biological... and other collaborators

Completed

A Study to Evaluate The Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Population Aged 18 Years Old and Above (COVID-19)

COVID-19

Jordan, Bahrain, Egypt, United Arab Emirates
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Hubei Provincial Center for... and other collaborators

Unknown

Evaluation of Safety and Immunogenicity of Combined Immunization of sIPV, DTaP and HepA

Vaccination

China
ABLE Human Motion S.L.
Hospital Asepeyo Barcelona; Biomechanical Engineering Lab (BIOMEC) - Universitat... and other collaborators

Completed

KAFO Orthoses Versus the ABLE Exoskeleton

Spinal Cord Injuries

Spain
Shanghai Chest Hospital
Geneplus-Beijing Co. Ltd.; Guangzhou Burning Rock Medical Examination Institute... and other collaborators

Unknown

A Prospective Study to Evaluate the Consistency of Next-Generation Sequencing(NGS)-Panels by Using Malignant Hydrothorax Form NSCLC

NSCLC | Malignant Hydrothorax

China
China National Biotec Group Company Limited
Peking University; Hubei Provincial Center for Disease Control and Prevention; Shaanxi Provincial Center for Disease Control and Prevention and other collaborators

Completed

To Evaluate the Immunogenicity and Safety of Sequential Immunization Schedules of Sabin IPV and bOPV

Vaccination | Reaction - Vaccine

China
China National Biotec Group Company Limited
Wuhan Institute of Biological Products Co., Ltd; Hunan Provincial Center for... and other collaborators

Not yet recruiting

Evaluation of Immunogenicity and Safety of COVID-19 Vaccine (Produced in Wuhan) in Patients With Hypertension and/or Diabetes

COVID-19 Pneumonia

China
Norwegian Institute of Public Health
University of Stellenbosch; European and Developing Countries Clinical Trials... and other collaborators

Recruiting

Evaluation of a Rapid Point-of-Care Serological Triage Test for Active TB (SeroSelectTB)

Tuberculosis, Pulmonary

South Africa, Tanzania, Ethiopia
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Guizhou Center for Disease... and other collaborators

Recruiting

Immunogenicity and Safety of an Inactivated SARS-CoV-2 Vaccine (Sinopharm BBIBP-CorV) Coadministered With Rabies Vaccine

COVID-19 | Rabies

China
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Hunan Provincial Center for... and other collaborators

Completed

Evaluation of Immunogenicity and Safety of COVID-19 Vaccine (Produced in Beijing) in Patients With Hypertension and/or Diabetes

COVID-19 Pneumonia

China
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Hunan Provincial Center for... and other collaborators

Not yet recruiting

Evaluation of Immunogenicity, Safety and Antibody Persistence of COVID-19 Booster Vaccine (Produced in Beijing) in Patients With Hypertension and/or Diabetes

COVID-19 Pneumonia

China
China National Biotec Group Company Limited
Wuhan Institute of Biological Products Co., Ltd; Hunan Provincial Center for... and other collaborators

Not yet recruiting

Evaluation of Immunogenicity, Safety and Antibody Persistence of COVID-19 Booster Vaccine (Produced in Wuhan) in Patients With Hypertension and/or Diabetes

COVID-19 Pneumonia

China
Sichuan Huiyu Pharmaceutical Co., Ltd
The First Hospital of Jilin University; Suzhou Guochen Biotek Co., Ltd.; Boji... and other collaborators

Completed

Bioequivalence Study of Ferric Carboxymaltose Injection in Participants With Iron Deficiency Anaemia

Iron Deficiency | Anaemia

China
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Wuhan Institute of Biological... and other collaborators

Unknown

Clinic Trial to Evaluate the Safety and Immunogenicity of Combined Immunization of sIPV and DTaP

Vaccination

China
China National Biotec Group Company Limited
Peking University; Shaanxi Provincial Center for Disease Control and Prevention and other collaborators

Unknown

Evaluation of the Safety and Immunogenicity of Hepatitis A Vaccine

Vaccination

China
Shanghai Jiao Tong University School of Medicine
Guangzhou Psychiatric Hospital; The First Affiliated Hospital of Zhengzhou... and other collaborators

Recruiting

Decreasing Risk of Psychosis by Sulforaphane (DROPS Trial)

Clinical High Risk Syndrome of Psychosis

China
Hospital Universitario Getafe
Cardiff University; Catholic University of the Sacred Heart; University Hospital... and other collaborators

Completed

Multi-Modal Intervention In Frail And Prefrail Older People With Type 2 Diabetes (MID-Frail)

Type 2 Diabetes Mellitus

Spain
Centers for Disease Control and Prevention
PATH; World Health Organization; MCM Vaccines B.V.; Pan American Health Organization and other collaborators

Completed

Needle-free Jet Injection of Reduced-dose, Intradermal, Influenza Vaccine in >= 6 to < 24-month-old Children

Influenza

Dominican Republic
ANRS, Emerging Infectious Diseases
Imperial College London; University College, London; Fred Hutchinson Cancer Center and other collaborators

Terminated

An HIV Vaccine Trial in Individuals Who Started ART During Primary or Chronic Infection (EHVAT01)

HIV-1-infection

Switzerland, United Kingdom
Bogomolets National Medical University
Danylo Halytsky Lviv National Medical University; Taras Shevchenko National... and other collaborators

Completed

Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults MASLD Patients (DELI_MASLD Study)

Hepatic Steatosis | Steatotic Liver Disease | Metabolic Dysfunction Associated Steatotic Liver Disease

Ukraine
Bogomolets National Medical University
Danylo Halytsky Lviv National Medical University; Taras Shevchenko National... and other collaborators

Completed

Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults NAFLD Patients (DELI_NAFLD Study)

Fatty Liver | Hepatic Steatosis | Non-Alcoholic Fatty Liver Disease | Non Alcoholic Fatty Liver

Ukraine
Bogomolets National Medical University
Danylo Halytsky Lviv National Medical University; Taras Shevchenko National... and other collaborators

Completed

Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Type 2 Diabetes Patients (DELI_Diab Study)

Obesity | Insulin Resistance | Type 2 Diabetes Mellitus in Obese | Type2 Diabetes | Insulin Sensitivity | Obesity, Abdominal

Ukraine
Beijing Tiantan Hospital
Fudan University; Huashan Hospital; West China Hospital; The First Affiliated Hospital... and other collaborators

Completed

Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events(TRACE)

Acute Ischemic Stroke

China
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.; Sichuan Center for Disease... and other collaborators

Completed

Evaluation of Immunogenicity and Safety of Combined Immunization of COVID-19 Vaccine (Produced in Beijing) and PPV23 / IIV4

Covid19 | Pneumonia, Pneumococcal | Influenza, Human

China
China National Biotec Group Company Limited
Wuhan Institute of Biological Products Co., Ltd; Henan Center for Disease Control... and other collaborators

Active, not recruiting

Evaluation of Immunogenicity and Safety of Combined Immunization of COVAX (Produced in Wuhan) and PPV23 / IIV4

Pneumonia, Pneumococcal | Influenza, Human | COVID-19 Pneumonia

China

Clinical Trials Sponsored by IO Biotech

Sponsors and Collaborators

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