Search clinical trials for: MGMT promoter-methylated glioblastoma

Total 2025 results

National Cancer Institute (NCI)

Completed

Pyrazoloacridine Plus Carboplatin in Treating Patients With Recurrent Glioma

Brain and Central Nervous System Tumors

United States, Canada
BioCryst Pharmaceuticals

Completed

BCX-1777 in Treating Patients With Refractory Cancer

Cancer

United States
University of Colorado, Denver
National Cancer Institute (NCI)

Completed

Cytotoxic T Cells and Interleukin-2 in Treating Adult Patients With Recurrent Brain Tumors

Brain and Central Nervous System Tumors

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma

Glioblastoma Multiforme

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas

Glioblastoma | Gliosarcoma

United States
Dr Andrea Rossetti

Completed

Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors

Brain and Central Nervous System Tumors | Seizure

Switzerland
Maastricht University Medical Center

Completed

Borderzone Sampling (BZS)

Glioblastoma | High Grade Glioma

Netherlands
Duke University
Genentech, Inc.

Completed

Phase (Ph) II Bevacizumab + Erlotinib for Patients (Pts) With Recurrent Malignant Glioma (MG)

Glioblastoma | Gliosarcoma

United States
University of California, San Francisco

Terminated

Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Imaging (MRI) Spectroscopy for Recurrent Glioma (GKS)

Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Extra-adrenal Paraganglioma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood... and other conditions

United States, Canada
Gilead Sciences

Terminated

Efficacy Study of CYT997 in Combination With Carboplatin in Glioblastoma

Glioblastoma Multiforme

Australia
Novartis Pharmaceuticals

Completed

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Lymphoma | Breast Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Melanoma (Skin) | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
GlaxoSmithKline

Completed

Pazopanib In Combination With Lapatinib In Adult Patients With Relapsed Malignant Glioma (VEG102857)

Glioma
Sanofi

Completed

A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas

Glioblastoma Multiforme | Malignant Gliomas | Mixed Gliomas

United States
National Cancer Institute (NCI)

Completed

Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Arsenic Trioxide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Tipifarnib and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer

Brain and Central Nervous System Tumors

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

Brain and Central Nervous System Tumors

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
Duke University
National Cancer Institute (NCI)

Withdrawn

Carmustine and O(6)-Benzylguanine in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Brain and Central Nervous System Tumors
Duke University
National Cancer Institute (NCI)

Completed

Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
Hoag Memorial Hospital Presbyterian

Completed

Cellular Adoptive Immunotherapy in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Duke University
Novartis Pharmaceuticals

Completed

Phase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG)

Glioblastoma | Gliosarcoma

United States
Grupo Español de Investigación en Neurooncología

Completed

Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patients

Glioblastoma

Spain
University Hospital, Bordeaux

Completed

Evaluation of [18F]-FMISO for Non Operated Glioblastoma (MISOGLIO)

Glioblastoma

France
Johann Wolfgang Goethe University Hospital

Unknown

Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery (IMAGER)

Glioma | Glioblastoma | Primary Malignant Neoplasm of Nervous System | Metastasis

Germany
Pfizer

Terminated

Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer

Advanced Breast Cancer (Parts 1 and 2) | Advanced Pancreatic Cancer (Part 1) | Advanced Colorectal Cancer (Part 1) | Advanced Cholangiocarcinoma (Part 1) | Advanced Glioblastoma Multiforme (Part 1)

United States, Spain, Hong Kong, Belgium, Australia, France
Duke University
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors

Brain and Central Nervous System Tumors

United States
Annick Desjardins
AstraZeneca

Completed

Ph I Dose Escalation Trial of Vandetanib in Combo w Etoposide for Malignant Gliomas

Glioblastoma | Gliosarcoma

United States
Annick Desjardins
Novartis Pharmaceuticals

Completed

Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG

Glioblastoma | Gliosarcoma

United States
Duke University
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Melanoma or Brain Tumors

Brain and Central Nervous System Tumors | Metastatic Cancer | Melanoma (Skin)

United States
Duke University
Schering-Plough

Completed

PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma

United States
Duke University
National Cancer Institute (NCI)

Completed

Carmustine Plus O(6)-Benzylguanine in Treating Patients With Recurrent or Progressive Gliomas of the Brain

Brain and Central Nervous System Tumors

United States
Duke University
Novartis; National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma

Osteoporosis | Brain Tumors | Central Nervous System(CNS)Malignancies

United States
Duke University
National Cancer Institute (NCI)

Completed

Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas

Brain and Central Nervous System Tumors

United States
Duke University

Completed

Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas

Brain and Central Nervous System Tumors

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

Lymphoma | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
Duke University
Genentech, Inc.; Eisai Inc.

Terminated

A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme | Malignant Glioma | Gliosarcoma

United States
National Cancer Institute (NCI)

Terminated

RO4929097 in Treating Patients With Recurrent Invasive Gliomas

Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Adult Brain Stem Glioma

Canada
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

Malignant Neoplasms of Eye, Brain and Other Parts of Central Nervous System

United States
National Cancer Institute (NCI)

Terminated

Neoadjuvant and Adjuvant Fenretinide Compared With Adjuvant Fenretinide Alone in Treating Patients Who Are Undergoing Surgical Resection For Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Terminated

Bortezomib in Treating Patients With Recurrent Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Duke University
National Cancer Institute (NCI); Novartis Pharmaceuticals

Completed

Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma

Glioblastoma | Gliosarcoma

United States
National Cancer Institute (NCI)

Terminated

Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States
National Cancer Institute (NCI)

Completed

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Chronic Myelogenous Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Relapsing Chronic Myelogenous Leukemia and other conditions

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction

Recurrent Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Bladder Cancer | Stage IV Bladder Cancer | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States

Search clinical trials for: MGMT promoter-methylated glioblastoma

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