Clinical Trials Sponsored by Lyric Pharmaceuticals

Total 19738 results

Gerstein, Hertzel, MD
Wyeth is now a wholly owned subsidiary of Pfizer; GlaxoSmithKline; Canadian Institutes... and other collaborators

Completed

The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial

Glucose Metabolism Disorders | Cardiovascular Disease | Impaired Glucose Tolerance
Institute of Hematology & Blood Diseases Hospital...
Fosun Pharmaceutical Distribution Jiangsu co., Limited

Not yet recruiting

Efficacy and Safety of Avatrombopag vs. Avatrombopag Combined With rhTPO in the Treatment of SAA

Anemia, Aplastic
Beijing Tide Pharmaceutical Co., Ltd
The Third Xiangya Hospital of Central South University

Not yet recruiting

Efficacy, Safety and Tolerability Study of Meloxicam Injection in Subjects After Abdominal Surgery

Pain, Post-operative

China
Sichuan Kelun Pharmaceutical Research Institute...
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Recruiting

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

Non-small Cell Lung Cancer

China
The Second Affiliated Hospital of Chongqing Medical...
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

The Efficacy and Safety of Tenofovir Amibufenamide to Treat Low-level Viraemia After Entecavir Treatment (POWER)

Chronic Hepatitis B

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Recruiting

SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer

Triple-negative Breast Cancer and HR+/HER2- BC

China
National Institute of Allergy and Infectious Diseases...
Otsuka Pharmaceutical Development & Commercialization, Inc.

Recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Delamanid in Combination With Optimized Multidrug Background Regimen (OBR) for Multidrug-Resistant Tuberculosis (MDR-TB) in HIV-Infected and HIV-Uninfected Children With MDR-TB

HIV Infections | Tuberculosis

Tanzania, India, South Africa, Botswana
Semmelweis University
National Research Develpment and Innovation Fund, Hungary; MEDITOP Pharmaceutical...

Active, not recruiting

The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain and Sciatic Pain "BETA" (BETA)

Low Back Pain

Hungary
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Active, not recruiting

KL-A167 Injection Combined With Cisplatin and Gemcitabine vs Placebo Combined With Cisplatin and Gemcitabine in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Recurrent or Metastatic

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Completed

KL-A167 Injection in Recurrent or Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Recurrent or Metastatic

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Completed

An Open, Multicenter Phase II Study to Evaluate the Safety and Efficacy of KL-A167 Injection in Relapsed or Refractory Classical Hodgkin's Lymphoma

Classical Hodgkin Lymphoma

China
The First Affiliated Hospital with Nanjing Medical...
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Unknown

SHR-1210 Combined With Apatinib Mesylate in the Perioperative Treatment of Hepatocellular Carcinoma (HCC-009)

Hepatocellular Carcinoma

China
The First Hospital of Jilin University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Single Drug as the Maintenance Treatment for Advanced NSCLC

Non-Small Cell Lung Cancer

China
RDO Pharm.
Beijing Pharbers Genesis Pharmaceutical Technology Co., Ltd.; MedAlly Solutions...

Completed

A Study of 99mTc-3PRGD2 Injection in Healthy Volunteers

Healthy

China
The First Affiliated Hospital of Zhengzhou University
Yichang Humanwell Pharmaceutical Co., Ltd., China

Unknown

the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation

Critical Illness
Cancer Institute and Hospital, Chinese Academy...
Biotech Pharmaceutical Co., Ltd.

Unknown

Nimotuzumab Plus Docetaxel and Capecitabine Versus Docetaxel and Capecitabine in the Treatment of Breast Cancer Patients

Breast Cancer

China
Cancer Institute and Hospital, Chinese Academy...
Simcere Pharmaceutical Co., Ltd

Unknown

Efficacy and Safety Study of Recombinant Endostatin Combined With Chemotherapy to Treat Advanced Colorectal Cancer

Colorectal Cancer

China
Samsung Medical Center
Korea Otsuka Pharmaceutical Co., Ltd.; Ministry of Health & Welfare, Korea

Completed

Effects of Atypical Antipsychotics on Appetite and Eating Behavior of Schizophrenia Patients

Schizophrenia | Schizoaffective Disorder

Korea, Republic of
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
The First Affiliated Hospital of Soochow University

Recruiting

Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula

Crohn's Disease | Anal Fistula | Complex Perianal Fistulas

China
The First Affiliated Hospital with Nanjing Medical...
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Neoadjuvant Therapy of HAIC（GEMOX） Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors

Intrahepatic Cholangiocarcinoma

China
Liling Zhang
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Prospective, Single Arm, Single Center Study of Duvelisib Combined With Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma (PTCL)

Newly Diagnosed Peripheral T-cell Lymphoma

China
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Recruiting

Clinical Trail of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021) in Participants Aged 18 Years and Older

SARS-CoV-2

Pakistan
Jiangsu Simcere Pharmaceutical Co., Ltd.
Shanghai Xianxiang Medical Technology Co., Ltd.; Simcere Zaiming

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0237 in Adult Participants With Advanced Solid Tumors

Locally Advanced Unresectable or Metastatic Solid Tumor

United States, China
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Not yet recruiting

Clinical Study of SARS-CoV-2 Variant mRNA Vaccine in Healthy Participants

SARS-CoV-2
Wanbangde Pharmaceutical Group Co., LTD
Second Affiliated Hospital, School of Medicine, Zhejiang University

Not yet recruiting

The Effect of Huperzine A Injection on Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage: a Pilot Study

Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage

China
Shandong University
Qianfoshan Hospital; Chenland Nutritionals lnc.; Jinan Hetai Pharmaceutical Technology...

Not yet recruiting

Effectiveness and Safety of EuBone® Capsules for Bone Health in Postmenopausal Women

Osteoporosis, Postmenopausal

China
National and Kapodistrian University of Athens
Ioulia And Irene Tseti Pharmaceutical Laboratories S.A.

Completed

Assessing the Efficacy of a Hydrogen Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief

Postoperative Pain | Dental Plaque | Wound Heal | Sjogren's Syndrome | Mouth Dryness | Gingival Inflammation | Biopsy Wound | Oral Dryness | Mouth; Wound

Greece
Boston University
United States Agency for International Development (USAID); Pharmaceutical...

Completed

Evaluating the Efficacy of Using a Digital Consumption Management Tool for Family Planning in Zambia

Family Planning

Zambia
Sun Yat-sen University
Innovent Biologics (Suzhou) Co. Ltd.; CSPC Pharmaceutical Group Limited

Completed

Efficacy and Safety of Preoperative Sintilimab Plus Nab-paclitaxel and Cisplatin in BR-ESCC Patients

Esophageal Squamous Cell Carcinoma

China
The First Affiliated Hospital with Nanjing Medical...
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Active, not recruiting

Pemetrexed and TAS-102 in Combination With Bevacizumab in Refractory Colorectal Cancer

Colorectal Neoplasms

China
Marinova Pty Ltd
University of South Carolina; Nutrasource Pharmaceutical and Nutraceutical...

Completed

Inflammatory and Immune Response After High Intensity Exercise

Inflammatory Response

United States
Pulmonary Research Institute of Southeast Michigan
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

ProAir Digihaler in COPD Disease Management: A Real World Study

COPD | COPD Exacerbation Acute

United States
Ahon Pharmaceutical Co., Ltd.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Unknown

A Phase I Study of FCN-411 in Advanced Non-small Cell Lung Cancer Chinese Patients With EGFR Positive Mutation

Lung Cancer

China
Sichuan Cancer Hospital and Research Institute
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Efficacy and Safety of Anlotinib Plus Platinum Plus Pemetrexed in T790M-negative NSCLC

Lung Cancer Metastatic

China
Hebei Medical University Fourth Hospital
Beijing 302 Hospital; CSPC Ouyi Pharmaceutical Co., Ltd.

Unknown

Nab-paclitaxel Plus Carboplatin Versus Nab-paclitaxel Plus Epirubicin in the Neoadjuvant Therapy for Breast Cancer

Breast Cancer | Triple-negative Breast Cancer | Nab-paclitaxel

China
Zhong Wang
Shanxi Zhendong pharmaceutical Co. LTD.

Completed

Post-marketing Safety Surveillance of Compound Kuh-seng Injection: a Registry Study

Adverse Drug Events | Adverse Drug Reactions | Severe Adverse Events | Safety Surveillance | Severe Adverse Reactions

China
Zhejiang Kanglaite Pharmaceutical Co.Ltd
LinkDoc Technology (Beijing) Co. Ltd.; NanJing PLA 81 Hospital

Unknown

A Multicenter Real World Study of Kanglaite for Cancer Cachexia

Cancer Cachexia

China
The First People's Hospital of Lianyungang
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Plus Chemotherapy for Patients With Advanced Non-small Cell Lung Cancer

Lung Neoplasms | Anlotinib | Docetaxel | S-1 | Pemetrexed

China
Washington University School of Medicine
TAP Pharmaceutical Products Inc.; Doris Duke Charitable Foundation

Completed

A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion

Otitis Media With Effusion

United States
Chong-Jin Kim
Hanmi Pharmaceutical Company Limited

Completed

Comparison of Effects Between Amlodipine and Hydrochlorothiazide in Combination With Losartan on 24-hr Central Blood Pressure in Hypertensive Patients

Hypertension

Korea, Republic of
Access Business Group
Fudan University; Sprim Advanced Life Sciences; Sinphar Pharmaceutical Co., Ltd

Completed

Effect of Ginko and Cistanche Against Fatigue Symptoms (GkoCist)

Fatigue | Mental Fatigue | Chronic Fatigue Syndrome
First Affiliated Hospital of Harbin Medical University
Shanghai baiying pharmaceutical technology Co., Ltd.

Unknown

Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis (EIAIETNKOA)

Osteoarthritis of Knee

China
National University Hospital, Singapore
Otsuka Pharmaceutical Co., Ltd.; Shin Nippon Biomedical Laboratories, Ltd.

Terminated

OPB-51602 in Locally Advanced Nasopharyngeal Carcinoma Prior to Definitive Chemoradiotherapy

Nasopharyngeal Carcinoma

Singapore
Shanghai Zhongshan Hospital
Shanghai Wu Mengchao Medical Foundation; Shanghai Ankang Pharmaceutical Co....

Completed

A Study to Evaluate the Efficacy and Safety of Add-on Therapy of Wuling Capsule in Epilepsy Patients With Depression

Depression | Epilepsy

China
Otsuka Pharmaceutical Development & Commercialization...
Center for International Blood and Marrow Transplant Research

Completed

PK-directed Dose Adjustment of IV Busulfan Conditioning Regimen for Autologous Stem Cell Transplant in Lymphoma Patients

Lymphoma

United States, Canada
Seoul National University Hospital
Kyowa Hakko Kirin Pharma, Inc.; Jeil-Kirin Pharmaceutical Inc.

Completed

Pharmacokinetic, Pharmacodynamic and Safety Evaluation After Single Oral Administration of KRN1493

Healthy

Korea, Republic of
Northwell Health
Pfizer; Stanley Medical Research Institute; Janssen Pharmaceutica N.V., Belgium

Completed

Antidepressant and Antipsychotic to Treat Attenuated Positive and Negative Symptoms

Psychotic Disorders | Prodromal Schizophrenia

United States
WPD Pharmaceuticals Sp. z o.o.
National Center for Research and Development, Poland; Worldwide Clinical Trials

Terminated

Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)

Recurrent Glioblastoma Multiforme

Poland
Shadia Jalal, MD
Astex Pharmaceuticals, Inc.; Indiana University School of Medicine

Completed

Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer

Small Cell Lung Cancer | Extensive-stage Small Cell Lung Cancer

United States
Rempex Pharmaceuticals (a wholly owned subsidiary...
Innovative Medicines Initiative; Universitätsklinikum Köln

Withdrawn

Safety and PK Trial Evaluating the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Minocin IV

Normal Healthy Volunteers

Austria

Clinical Trials Sponsored by Lyric Pharmaceuticals

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