Clinical Trials Sponsored by BTG Ltd.

Total 17130 results

TG Therapeutics, Inc.

Recruiting

A Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk (PROVIDE)

Relapsing Multiple Sclerosis

United States
TG Therapeutics, Inc.

Recruiting

Study to Evaluate Efficacy When Transitioning From a Current Disease Modifying Therapy (DMT) to Ublituximab (ENHANCE)

Relapsing Multiple Sclerosis

United States
TG Therapeutics, Inc.

Terminated

Ublituximab + TGR-1202 Compared to Obinutuzumab + Chlorambucil in Participants With Untreated and Previously Treated Chronic Lymphocytic Leukemia (UNITY-CLL)

Chronic Lymphocytic Leukemia

United States, Israel, Italy, Poland, Russian Federation, Spain, United Kingdom
TG Therapeutics, Inc.

Active, not recruiting

Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Follicular Lymphoma | Marginal Zone Lymphoma | DLBCL | CLL | MCL | Indolent Lymphoma | Richter's Transformation | SLL | Mediastinal Large B-cell Lymphoma | Aggressive Lymphoma

United States
TG Therapeutics, Inc.

Completed

Study of TG-1801 in Subjects With B-Cell Lymphoma

B-Cell Lymphoma

Australia
TG Therapeutics, Inc.

Terminated

Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax

Chronic Lymphocytic Leukemia

United States
TG Therapeutics, Inc.

Completed

Study of the Efficacy and Safety of Ublituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

B-cell Lymphoma | Marginal Zone Lymphoma | Primary Central Nervous System Lymphoma | Waldenstrom's Macroglobulinemia | Non-Hodgkins Lymphoma | Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL)

United States
TG Therapeutics, Inc.

Completed

Ublituximab + Ibrutinib in Select B-cell Malignancies

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia

United States
TG Therapeutics, Inc.

Terminated

Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma (UNITY-NHL)

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Small Lymphocytic Lymphoma

United States, Poland, Australia, Italy, United Kingdom, Israel, Korea, Republic of, Slovakia, Spain
TG Therapeutics, Inc.

Completed

Phase IIa Study of Ublituximab in Participants With Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis

United States
TG Therapeutics, Inc.

Completed

Novel PI3K Delta Inhibitor TGR-1202, in Combination With Brentuximab Vedotin for Hodgkin's Lymphoma Patients

Hodgkin's Lymphoma

United States
BG Trauma Center Tuebingen

Completed

Reconstruction of Digital Nerve Lesions With Muscle-in-Vein Conduits

Peripheral Nerve Injury Upper Limb
BG Trauma Center Tuebingen

Completed

Impact of Associated Abdominal Injuries on Clinical and Operative Outcome in Pelvic Injuries

Acetabular Fracture | Polytrauma | Abdominal Trauma | Pelvic Ring Fracture

Germany
BG Trauma Center Ludwigshafen

Unknown

Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression (TalarAVN)

Avascular Necrosis of Bone

Germany
Mirka Ltd
Clinius Ltd

Completed

A Pre-market Study to Evaluate the Performance and Safety of a Skin Preparation Device for Removal of Dry Crusty Skin

Keratosis, Actinic | Hyperkeratotic Callus | Actinic Lesion | Solar Keratosis/Sunburn | Hyperkeratosis | Hyperkeratotic; Lesion | Hyperkeratotic Actinic Keratosis

Finland
Salus Ltd.
TheraVitae Ltd.

Completed

Autologous Angiogenic Cell Precursors (ACPs) for the Treatment of Peripheral Artery Disease

Critical Limb Ischemia

Hungary
Janssen-Cilag Farmaceutica Ltda.
Janssen Korea, Ltd., Korea

No longer available

An Expanded Access Program for Decitabine in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes

Hong Kong, Brazil, Thailand
BG Trauma Center Tuebingen

Completed

Pelvic Binder vs. Pelvic C-clamp for Bleeding Control

Polytrauma | Pelvic Ring Fracture | Pelvic Bleeding

Germany
BG Trauma Center Tuebingen

Unknown

Remote Ischemic Conditioning to Reduce Burn Wound Progression (RIC in burns)

Burns

Germany
BG Trauma Center Ludwigshafen

Unknown

Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression (TalarAVN)

Avascular Necrosis of Bone

Germany
BG Trauma Center Tuebingen

Completed

Muscle-in-vein Conduits for Digital Nerve Reconstruction

Sensory Recovery

Germany
BG Trauma Center Tuebingen

Completed

The Role of Antibiotics After Surgical Treatment of Simple Hand Infections: A Prospective Study

Hand Infections

Germany
H Scott Boswell
Takeda

Terminated

Study Augmenting TAK-659 Action in Relapsed/Refractory AML by Addition Ofthe Proteasome Inhibitor Ixazomib

AML | AML, Adult

United States
Nasser Hanna
Genentech, Inc.

Terminated

Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung Cancer

NSCLC Stage IV | NSCLC, Recurrent

United States
Palo Alto Veterans Institute for Research
Big Health Inc.

Active, not recruiting

A Pilot Study of Digital Cognitive Behavioral Therapy for Veterans

Insomnia

United States
University of Ulster
Devenish Nutrition, Lagan House, 19 Clarendon Road, Belfast, BT1 3BG; Agri-Food...

Completed

Vitamin D Enriched Meat Project (Acute Study)

Vitamin D Deficiency

United Kingdom
Paion UK Ltd.
Chiltern International Ltd.; HFL Ltd.

Completed

An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours

Postoperative Pain

France, Germany, Netherlands, Poland, United Kingdom, Czechia
Muhammad Furqan
AstraZeneca

Recruiting

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

United States
Big Health Inc.
University of California, San Francisco

Completed

Digital CBT-I for Insomnia Disorder (CrEDIT)

Insomnia Disorder

United States
Nelson Yee
Ipsen

Active, not recruiting

Liposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:

Locally Advanced Pancreatic Carcinoma(LAPC)

United States
Dwight Owen
Genentech, Inc.

Recruiting

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
John Quigley
Pfizer; AbbVie

Active, not recruiting

Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113

Acute Myeloid Leukemia

United States
Monika Joshi, MD
AstraZeneca

Active, not recruiting

Durvalumab And Radiation Therapy Followed by Adjuvant Durvalumab in Patients With Urothelial Cancer (T2-4 N0-2 M0) of the Bladder (DUART)

Urothelial Cancer

United States
Cardiovalve Ltd.
Meditrial Europe Ltd.

Recruiting

Cardiovalve Transfemoral System - FIM Study

Mitral Regurgitation

Lithuania
Vensica Therapeutics Ltd.
Blueclinical, Ltd.

Completed

Clinical Trial for the Assessment of Safety, Usability and Efficacy of the Vixe Combination for OAB in Female Subjects (XAVIER)

Overactive Bladder

Portugal
Nanomedic Technologies Ltd.

Completed

Evaluation of the SpinCare™ System in the Treatment of Partial Thickness Burns (SPINCARE2)

Partial Thickness Burn

Israel
Nanomedic Technologies Ltd.

Completed

Evaluation of the SPINNER Device for the Application of Wound Dressing: Treatment of Split Skin Graft Donor Sites (SPINNER01)

Wound of Skin

Israel
Danisco
4Pharma Ltd.; Medfiles Ltd.

Completed

Next Generation Probiotics (NGPs) for Metabolic Health

Microbial Colonization
Calcivis Ltd
Medsource UK Ltd.

Completed

Safety and Performance Evaluation of the Calcivis System

Dental Caries

United Kingdom
Targia Pharmaceuticals Ltd.
SoluBest Ltd.

Unknown

Comparative Bioavailability Study of Omexa Sumatriptan vs. Imitrex® in Healthy Volunteers

Migraine
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Calcivis Ltd
Medsource UK Ltd.

Completed

Caries Lesion Activity in Orthodontic Patients - Calcivis System

Dental Caries

United Kingdom
TyrNovo Ltd.

Active, not recruiting

A Study to Evaluate NT219 Alone and in Combination With ERBITUX® (Cetuximab) in Adults With Advanced Solid Tumors and Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Carcinoma of Head and Neck | Metastatic Solid Tumor | Colorectal Adenocarcinoma | Solid Tumor, Adult | Recurrent Solid Tumor

United States, Israel
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With Chronic Idiopathic Cough

Chronic Idiopathic Cough

United Kingdom, Ireland
University of Illinois at Chicago
William T. Grant Foundation; Big Brothers Big Sisters of America; Herrera Consulting...

Recruiting

Culturally Smart Relationships Study (CSR)

Racism

United States
Massachusetts General Hospital
TG Therapeutics

Terminated

Umbralisib and Rituximab as Initial Therapy for Patients With Follicular Lymphoma and Marginal Zone Lymphoma

Lymphoma | Follicular Lymphoma | Marginal Zone Lymphoma | Follicular Lymphoma, Grade 1 | Follicular Lymphoma Grade IIIa | Marginal Zone B Cell Lymphoma | Follicular Lymphoma Grade 2

United States
Henry Ford Health System
University of Michigan; Big Health Inc.

Active, not recruiting

Sleep To Reduce Incident Depression Effectively (STRIDE)

Major Depressive Disorder | Rumination | Insomnia, Primary

United States
University College Dublin
Irish Cancer Society; Big Health Inc.; myPatientSpace

Completed

The Menopause After Cancer Study (MACS)

Cancer | Insomnia | Menopause

Ireland
Kathy Miller
Millennium Pharmaceuticals, Inc.; Big Ten Cancer Research Consortium

Terminated

MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma

HCC | Hepatocellular Carcinoma | Liver Cancer

United States
Natalie Callendar
Bristol-Myers Squibb

Withdrawn

Phase II Study of Immunomaintenance Using POmalidomide With Elotuzumab afteR Second Autologous Transplant (Immuno-POWER)

Multiple Myeloma

Clinical Trials Sponsored by BTG Ltd.

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