Clinical Trials Sponsored by Chiesi Foundation

Total 20987 results

Chiesi Farmaceutici S.p.A.

Completed

A Single Arm 48-Week Follow-on Safety Study to a Core Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI® (CT03Ext)

Cystic Fibrosis

Ukraine, France, Poland
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 (CHF6001Ext)

Chronic Obstructive Pulmonary Disease

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

International Cross-sectional and Longitudinal Assessment on Asthma Control (Liaison) (LIAISON)

Asthma

Italy
Chiesi Farmaceutici S.p.A.

Completed

A Study Comparing the Pharmacokinetic, Pharmacodynamic and Safety of CHF 1535 (Fixed Combination of Beclomethasone + Formoterol) Administered Via the NEXT DPI, Versus the Free Combination of Licenced Beclomethasone DPI and Formoterol DPI in Asthmatic Adolescent and Adult Patients. (ADONE)

Asthma

United Kingdom, Denmark
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose in Healthy Volunteers, Repeat Doses in Asthmatic Patients and of Single Dose in COPD Patients of CHF6366

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
Chiesi SA/NV

Unknown

Adherence Evaluation in COPD

COPD | Adherence, Treatment

Belgium
Chiesi Farmaceutici S.p.A.

Completed

Functional Respiratory Imaging Study (FRI) (FRI)

Chronic Obstructive Pulmonary Disease

Belgium, Hungary
Chiesi Farmaceutici S.p.A.

Completed

A Study Comparing the Efficacy and Safety of CHF 1535 (BDP +FF) Inhalation Powder, Administered Via the NEXT Inhaler, Versus CHF 1535 (BDP +FF), Administered Via a pMDI, in Moderate to Severe Asthma

Asthma

Germany
Chiesi Farmaceutici S.p.A.

Completed

Multicentre, Open Label, Randomized, Two-arm, Parallel-group Study to Assess Efficacy and Safety of ENVARSUS® Compared With Tacrolimus Used as Per Current Clinical Practice in the Initial Maintenance Setting in de Novo Kidney Transplant Patients (STEADY)

End Stage Renal Disease

Italy
Chiesi Farmaceutici S.p.A.

Completed

An Open Label Placebo Study to Assess the Inhalation Profile in Asthmatic Patients Using the Nexthaler® Dry Powder Inhaler (DPI) Device (NEXThalerPIF)

Asthma

Italy
Chiesi Farmaceutici S.p.A.

Completed

Efficacy of CHF1535 Via NEXT DPI Versus pMDI and BDP DPI100µg on PeakExpiratoryFlow in Asthmatic Patients (Neptune)

Asthma

Poland
Chiesi Farmaceutici S.p.A.

Completed

Next DPI LABA, Multicentre, 5-way Cross-over, Adult Asthmatic Patients

Asthma

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Tolerability of Beclomethasone Plus Salbutamol in HFA pMDI Fixed Combination vs Beclomethasone Plus Salbutamol in CFC pMDI Fixed Combination in a 12-week Treatment Period of Adult Patients With Uncontrolled Asthma

Bronchial Asthma

Spain, Italy, Russian Federation, Ukraine
Chiesi Farmaceutici S.p.A.

Completed

A Study in Patients With Chronic Obstructive Pulmonary Disease (FUTURE)

Chronic Obstructive Pulmonary Disease

Italy
Chiesi Farmaceutici S.p.A.

Completed

Safety, Tolerability and Efficacy of 28-day Inhaled CHF 6001 DPI in COPD Patients

COPD

United Kingdom, Ireland
Chiesi Farmaceutici S.p.A.

Completed

A Study in Patients With Asthma (NELSON)

Asthma

Italy
Chiesi Farmaceutici S.p.A.

Completed

Prevalence and Reversibility of Lung Hyperinflation in Asthma (Dist'air2)

Asthma

France
Chiesi Farmaceutici S.p.A.

Completed

Observational Study on the Prophylactic Use of Curosurf in Neonatal Respiratory Distress Syndrome (RDS)

Respiratory Distress Syndrome, Newborn

France
Chiesi Farmaceutici S.p.A.

Completed

Evaluation of Possible Effects on the QTc Interval of CHF 4226 pMDI in Healthy Volunteers (CT14)

Chronic Obstructive Pulmonary Disease

United States
Chiesi Italia
Gesellschaft für Therapieforschung mbH

Not yet recruiting

Observational Study on Therapy Pathways of Asthamics Treated With ICS/LABA/LAMA Therapy in a Real-world Setting (TRIMAXIMIZE)

Asthma
Liverpool Heart and Chest Hospital NHS Foundation...

Recruiting

Feasibility of Pulsed Field Ablation Under Mild Conscious Sedation

Atrial Fibrillation

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...

Withdrawn

Ivabradine and Post-revascularisation Microcirculatory Dysfunction (MICRO-PCI)

Coronary Artery Disease | Angina

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...

Completed

Investigating the Incretin Effect in Cystic Fibrosis (IECF)

Cystic Fibrosis

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...

Unknown

Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery (AZATAAR)

Thoracic Aneurysm

United Kingdom
DR. DIANE CHISESI NFS. MD. PHD.
IRB

Not yet recruiting

Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant Joint Tumor (NASBP-B-09)

Chronic Pain | Metastatic Breast Cancer | Tumor | Muscle Neoplasms

United States
Liverpool Heart and Chest Hospital NHS Foundation...

Withdrawn

The Effect Of Aspirin On Survival in Lung Cancer

Non Small Cell Lung Cancer | Aspirin | Survival

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...

Completed

How Effective Are Antithrombotic Therapies in Primary Percutaneous Coronary Intervention (HEAT-PPCI)

Acute ST Elevation Myocardial Infarction

United Kingdom
China International Medical Foundation
Chinese Society of Clinical Oncology

Unknown

A Trial of Endostar in Patients With Carcinoma of the Head and Neck

Nasopharyngeal Neoplasms

China
Liverpool Heart and Chest Hospital NHS Foundation...

Not yet recruiting

Pulsed Field Ablation During Left Atrial Appendage Occlusion: A Randomised Controlled Trial (PLANET-AF)

Atrial Fibrillation

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...

Not yet recruiting

Dynamic Chest X-ray With Simultaneous Spirometry (DynaSSaur)

Cystic Fibrosis
Liverpool Heart and Chest Hospital NHS Foundation...

Withdrawn

Development of Diabetes in Adults With Cystic Fibrosis (CF) (CF-DIABETES)

Cystic Fibrosis

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...

Unknown

Substrate Ablation and Remodelling in Non-paroxysmal Atrial Fibrillation (AF) (SMAAN-PAF)

Atrial Fibrillation

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Papworth Hospital NHS Foundation Trust

Completed

The SoundScar Study The SOUNDSCAR Study (SoundScar)

Ventricular Tachycardia | Ischemic Cardiomyopathy

Australia, United Kingdom
China International Medical Foundation
Chinese Society of Clinical Oncology

Unknown

Apatinib Combined With S-1 for the Treatment of Recurrent/Metastatic Head and Neck Malignancies (Y-HR2017-025)

Head and Neck Cancer

China
Fundacion Miguel Servet
Hospital Universitario Getafe; Matia Foundation

Unknown

Impact of a Multicomponent Exercise Program on Functional Capacity in Frail Aged Participants With Cognitive Decline

Cognitive Impairment | Frail Elderly Syndrome

Spain
Chiesi SAS
Kappa Santé

Recruiting

Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) in Chronic Obstructive PulmoNary Disease in rEal-world Settings: Health-related Quality of Life Patient' eXpectations and characterisTics: the TriNEXT Study (TriNEXT)

COPD

France
ApoPharma

Completed

Study of Parkinson's Early Stage With Deferiprone (SKY)

Parkinson's Disease

United Kingdom, France, Germany, Canada
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Safety, Efficacy, & PK of PRX-102 in Patients With Fabry Disease Administered Intravenously Every 4 Weeks (BRIGHT)

Fabry Disease

United States, Denmark, Belgium, United Kingdom, Norway, Italy, Czechia
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Extension Study of PRX-102 for up to 60 Months

Fabry Disease

United States, Spain, United Kingdom, Paraguay
ApoPharma

Completed

Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload (TWICE)

Iron Overload Due to Repeated Red Blood Cell Transfusions

United States, Canada, Greece, Italy
Calmy Alexandra
University Hospital, Geneva; Swiss National Science Foundation; Swiss Heart Foundation and other collaborators

Terminated

ER Niacin/Laropiprant Impact on Cardiovascular Markers and Atheroprogression in HIV-infected Individuals on cART (NILACH)

Atherosclerosis | HIV

Switzerland
University Hospital Southampton NHS Foundation...
Liverpool Heart and Chest Hospital NHS Foundation Trust

Unknown

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes? (RIPCORD 2)

Chest Pain | Acute Coronary Syndrome | Stable Angina | Non ST Segment Elevation Acute Coronary Syndrome

United Kingdom
ApoPharma

Terminated

Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias

Iron Overload | Sickle Cell Disease | Other Anemias

United States, United Kingdom, Egypt, Canada, Saudi Arabia
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function (BALANCE)

Fabry Disease

United States, Netherlands, Hungary, United Kingdom, Czechia, Norway, Slovenia, Spain, Finland, France, Italy, Switzerland
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Dose-ranging Study of PRX-102 in Adult Fabry Disease Patients

Fabry Disease

United States, Serbia, Spain, United Kingdom, Australia, Paraguay
Chiesi Farmaceutici S.p.A.
Cromsource

Completed

Trial on Safety and Efficacy of Velmanase Alfa Treatment in Pediatric Patients With Alpha-Mannosidosis (rhLaman-08)

Alpha-Mannosidosis

France, Denmark, Austria, Germany, Italy
ApoPharma

Terminated

Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias (FIRST)

Iron Overload | Sickle Cell Disease | Other Anemias

United States, Turkey, United Kingdom, Egypt, Saudi Arabia, Brazil, Canada, Tunisia
Chiesi Farmaceutici S.p.A.
Cromsource

Completed

Envarsus® Once Daily With Everolimus in Elderly Kidney Transplant Recipients: Pharmacokinetic and Clinical Study

Kidney Transplantation

Italy
University of Alabama at Birmingham
Centre for Infectious Disease Research in Zambia; Chiesi Foundation

Completed

Impact of Hindmilk on Weight Gain Among Moderate to Very Preterm Infants in Zambia

Postnatal Growth Restriction

Zambia

3

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