Clinical Trials Sponsored by Kyowa Hakko Kogyo Co., Ltd.

Total 225 results

Kyowa Kirin Co., Ltd.

Terminated

Study of KHK 4323 in Healthy Volunteers and Subjects With Atopic Dermatitis

Atopic Dermatitis

Japan
Kyowa Kirin Co., Ltd.

Completed

Open Label Extension Study of AMG 531 in Japanese Subjects With ITP

Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Japan
Kyowa Kirin Co., Ltd.

Completed

Study of Benralizumab (KHK4563) in Patients With Eosinophilic Chronic Rhinosinusitis

Eosinophilic Chronic Rhinosinusitis

Japan
Kyowa Kirin Co., Ltd.

Completed

A Study of KW-6356 in Subjects With Early Parkinson's Disease

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

Phase 3 Study of KHK7580

Secondary Hyperparathyroidism

Japan
Kyowa Kirin Co., Ltd.

Completed

Multicenter, Randomized, Open-label, Parallel-group Study to Compare mLSG15 + KW-0761 to mLSG15

Adult T-cell Leukemia-Lymphoma

Japan
Kyowa Kirin Co., Ltd.

Completed

Phase II Study of KW-0761 in Subjects With CCR4-positive Adult T-cell Leukemia-lymphoma

Adult T-cell Leukemia-lymphoma

Japan
Kyowa Kirin Co., Ltd.

Terminated

A Phase 3 Clinical Study of KW-3357 in Patients With DIC (3357-006)

Disseminated Intravascular Coagulation (DIC)

Japan
Kyowa Kirin Co., Ltd.

Completed

A Clinical Study of KW-3357 in Patients With DIC (3357-005)

Disseminated Intravascular Coagulation (DIC)

Japan
Kyowa Kirin Co., Ltd.

Completed

An Open-label Study of KW-3357 (3357-004)

Disseminated Intravascular Coagulation (DIC)

Japan
Kyowa Kirin Co., Ltd.

Completed

Study of ARQ 197 Monotherapy (ARQ 197-004)

Gastric Cancer

Japan, Korea, Republic of
Kyowa Kirin Co., Ltd.

Completed

A Study of ARQ 197 in Combination With Erlotinib

Advanced/Recurrent Non-small-cell Lung Cancer

Japan
Kyowa Kirin Co., Ltd.

Completed

A Comparative Study of KW-2246 (2246-004)

Cancer Related Pain (Breakthrough Pain)

Japan
Kyowa Kirin Co., Ltd.

Completed

An Intra-individual Titration Study of KRN1493 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Intractable Primary Hyperparathyroidism

Primary Hyperparathyroidism | Parathyroid Carcinoma | Hypercalcemia

Japan
Kyowa Kirin Co., Ltd.

Completed

Study of ARQ 197 in Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma

Japan
Kyowa Kirin Co., Ltd.

Terminated

A Glomerular Filtration Rate (GFR) Measuring Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes | Chronic Kidney Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Single Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease.

Alzheimer's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

An Open-label, Non-controlled Study of KHK4827 in Subjects With Psoriasis

Psoriasis

Japan
Kyowa Kirin Co., Ltd.

Completed

Safety Study of AMG 531 in Japanese Subjects With ITP

Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Kyowa Kirin Co., Ltd.

Completed

A Comparative Study of KHK6188

Postherpetic Neuralgia

Japan
Kyowa Kirin Co., Ltd.

Completed

Phase I Study of KW-0761 in Relapsed Patients With CCR4-Positive ATL and PTCL

Adult T-Cell Leukemia and Lymphoma (ATL) | Adult Peripheral T-Cell Lymphoma (PTCL)

Japan
Kyowa Kirin Co., Ltd.

Completed

A Double-blind Study of KRN321 for the Treatment of Anemia in Cancer Patients

Anemia

Japan
Kyowa Kirin Co., Ltd.

Completed

Long-Term Safety Study of KW-6002 (Istradefylline) in Parkinson's Disease Patients (6002-010)

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease

Parkinson's Disease

Japan
Kyowa Kirin, Inc.

Recruiting

A Study of KK2269 in Adult Participants With Solid Tumors

Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

Japan
Kyowa Kirin, Inc.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration (nAMD)

United States, Japan, Korea, Republic of, Australia
Kyowa Kirin, Inc.

Completed

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

United States
Kyowa Kirin, Inc.

Completed

Study of Burosumab (KRN23) in Adults With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS)

Tumor Induced Osteomalacia (TIO) | Epidermal Nevus Syndrome (ENS)

United States
Kyowa Kirin, Inc.

Terminated

A Study of a Monoclonal Antibody, KW-2871, in Patients With Advanced Melanoma

Stage IV Melanoma

United States
Kyowa Kirin, Inc.

Terminated

Study of KHK2823 in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United Kingdom
Kyowa Kirin, Inc.

Completed

Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis

Digestive System Diseases | Gastrointestinal Diseases | Colonic Diseases | Intestinal Diseases | Abdominal Pain | Inflammatory Bowel Diseases | Ulcerative Colitis | Colitis | Colitis, Ulcerative | Autoimmune Disease

Hungary, Russian Federation, Serbia, United States, Poland, Czechia, Romania
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of an Anti-OX40 Monoclonal Antibody (KHK4083) in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States, Canada, Germany, Japan
Kyowa Kirin, Inc.

Completed

A Long-Term, Safety Study With a Flexible Dose Range of KW-6002 in Patients With Motor Response Complications on Levodopa/Carbidopa Therapy

Parkinson's Disease

United States
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

A Study of Istradefylline (KW-6002) as Monotherapy in Parkinson's Disease (PD) Patients

Parkinson's Disease | Movement Disorder Syndrome

United States
Kyowa Kirin, Inc.

Completed

KW-0761 or Investigator's Choice in Subjects With Previously Treated Adult T-cell Leukemia-Lymphoma (ATL)

Adult T-cell Leukemia-Lymphoma

United States, United Kingdom, Belgium, France, Brazil, Peru
Kyowa Kirin, Inc.

Completed

A Study of Istradefylline (KW-6002) in Treating Patients With Parkinson's Disease on Levodopa

Parkinson's Disease

United States
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

United States, Korea, Republic of, Canada, Japan, France, Denmark
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Terminated

An Extension of Istradefylline in North American Parkinson's Disease Patients Who Have Completed Study 6002-INT-001

Parkinson's Disease

United States
Kyowa Kirin, Inc.

Terminated

An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous Leukemia

Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

United States
Kyowa Kirin, Inc.

Completed

Phase I Study of KRN330 Monoclonal Antibody in Patients With Colorectal Cancer

Colorectal Cancer

United States
Kyowa Kirin, Inc.

Completed

12-Week, Double-Blind, Placebo-Controlled, Randomized Study of the Efficacy of 40 mg/Day KW-6002 in Parkinson's Disease Patients on Levodopa/Carbidopa

Parkinson's Disease

United States
Kyowa Kirin, Inc.

Completed

12-Week, Double-Blind, Placebo-Controlled Study of 20 and 60 mg/Day Istradefylline in Parkinson's Disease Patients on Levodopa/Carbodopa

Parkinson's Disease

United States
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome

Sleep Disorder | Restless Legs Syndrome

United States
Kyowa Kirin, Inc.

Completed

KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

Carcinoma | Cancer | Solid Tumor

United States, France
Kyowa Kirin, Inc.

Terminated

KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer

Urothelial Carcinoma

United States, Spain
Kyowa Kirin Pharmaceutical Development Ltd

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age

X-linked Hypophosphatemia (XLH)

Sweden, Spain, United Kingdom, Italy, Austria, France
Kyowa Kirin, Inc.
AstraZeneca

Completed

Study of Mogamulizumab + MEDI4736 (Durvalumab) and Mogamulizumab + Tremelimumab in Subjects w/ Advanced Solid Tumors

Advanced Solid Tumors

United States
Pfizer
Kyowa Kirin Co., Ltd.

Terminated

A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors

Advanced/Metastatic Solid Tumors

United States
Kyowa Kirin Co., Ltd.
Ono Pharmaceutical Co. Ltd

Completed

Study of Combination Therapy With Mogamulizumab (KW-0761) and Nivolumab (ONO-4538/BMS-936558) in Subjects With Advanced Solid Tumors

Solid Tumor

Japan

Clinical Trials Sponsored by Kyowa Hakko Kogyo Co., Ltd.

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