Clinical Trials Sponsored by MED Institute, Incorporated

Total 2169 results

EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

First in Human Study of M6223

Metastatic Solid Tumors

United States, Canada
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

M3541 in Combination With Radiotherapy in Solid Tumors

Solid Tumors

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC

Cholangiocarcinoma | Biliary Tract Cancer | Gallbladder Cancer

Korea, Republic of, United States, Taiwan, China, Argentina, Australia, Brazil, Chile, France, Germany, Italy, Japan, Poland, Spain, United Kingdom
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer

Uterine Cervical Neoplasms

Korea, Republic of, United States, France, Belgium, China, Argentina, Spain, Australia, Russian Federation, Brazil, Hungary, Japan
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

M7824 in Combination With Chemotherapy in Stage IV Non-small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

United States, Belgium, France
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)

Small-cell Lung Cancer

Spain, Belgium, United States, China, Japan, Italy, France
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

Locally Advanced Rectal Cancer

United States, Spain
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Study of Avelumab-M3814 Combinations

Solid Tumors | Oncology

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

M8891 First in Human in Solid Tumors (M8891)

Metastatic Renal Cell Carcinoma | Advanced Solid Tumors

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)

Solid Tumors

United States, Korea, Republic of, Taiwan, France, United Kingdom, Belgium, Czechia, Germany, Poland
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Phase I/II Study of Avelumab in Pediatric Cancer Subjects

Lymphoma | Refractory or Relapsed Solid Tumors

Korea, Republic of, United States, Canada, Belgium, Denmark
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS)

Relapsing-remitting Multiple Sclerosis

United States, Germany
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Withdrawn

Study of M4344 in Combination With Niraparib

Breast Cancer | Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12) (COMBO)

Advanced Solid Tumors

Spain, United States, Netherlands, Hungary, Italy, France, Belgium
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)

Small Cell Lung Cancer

Belgium, Denmark, Italy, United States, Bulgaria, Canada, Czechia, Germany, Hungary, Poland, Romania, Spain, United Kingdom
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200)

Carcinoma, Non-Small-Cell Lung

Spain, United States, Taiwan, Belgium, Denmark, Switzerland, Argentina, Israel, Italy, Croatia, United Kingdom, Korea, Republic of, Russian Federation, Slovakia, Japan, Bulgaria, Poland, Hungary, Australia, Turkey, Peru, Chile, Mexico, Czech... and more
EMD Serono Research & Development Institute, Inc.
Nordic Bioscience A/S

Completed

A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee (FORWARD)

Osteoarthritis, Knee

Estonia, Romania, Hong Kong, Czechia, Denmark, Poland, Argentina, United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

First-in-Human Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of VX-984 in Combination With Chemotherapy

Advanced Solid Tumor

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

Abituzumab in SSc-ILD

Systemic Sclerosis-associated Interstitial Lung Disease

United States, Canada, Italy, Poland, Spain, Argentina, Australia, Israel, United Kingdom
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Safety and Efficacy Study of M2951 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Germany
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Use of High-Resolution Microendoscopy (HRME) in Patients With Cervical Dysplasia

Cervical Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Middle and High School Students' Reactions to a Health Interactive Website: ASPIRE Reactions

Tobacco Use Cessation | Tobacco Prevention

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Doxycycline, Temozolomide and Ipilimumab in Melanoma

Melanoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Unknown

Epidemiology Controls Using Healthy Participants

Healthy

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Intraperitoneal tgDCC-E1 and Intravenous Paclitaxel in Women With Platinum-Resistant Ovarian Cancer

Ovarian Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Withdrawn

Adoptive Therapy Using Antigen-Specific CD4 T-Cells

Melanoma | Sarcoma
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

Colorectal Cancer | Lynch Syndrome | T Cells

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Patient-Specific Decision Aid System for Shared Decision Making About Breast Reconstruction

Breast Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Effects of Yoga in Breast Cancer Patients

Breast Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Reducing Cancer Disparities Among Latinos in Texas

Psychosocial Problem

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Unknown

Determinants of Multiple Health Risk Behaviors Among Latinos

Cancer | Risk Factors in Latinos

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT)

Non-small-cell Lung Cancer

United States
Desmond Tutu HIV Foundation
National Institutes of Health (NIH); University of Cape Town; Zeteo Tech Incorporated

Completed

Bioaerosol Sampling in Suspected Pulmonary Tuberculosis

Pulmonary Tuberculosis Confirmation by Sputum Microscopy With or Without Culture

South Africa
John Sievenpiper
Canadian Institutes of Health Research (CIHR); The Physicians' Services Incorporated...

Unknown

Meta-analyses of Liquid Versus Solid Calories and Body Weight

Cardiovascular Diseases | Obesity | Diabetes Mellitus | Overweight | Metabolic Syndrome | Prediabetic State | Chronic Disease

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study

Peripheral Neuropathy

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Relaxation for Women With Breast Cancer Undergoing Radiotherapy

Breast Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Parenteral Hydration in Advanced Cancer Patients

Dehydration | Advanced Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Motivational Interviewing for Physical Activity

Cancer

United States
Kenneth Sherman
National Heart, Lung, and Blood Institute (NHLBI); Genentech, Inc.; Vertex Pharmaceuticals...

Completed

Viral Kinetics in HCV Clearance in Subjects With Hemophilia (HCV/Hemophil)

Hemophilia | Chronic Hepatitis C

United States
Karolinska Institutet
The International Federation of Red Cross and Red Crescent Societies

Completed

Outcome for Patients With War-Associated Extremity Wound Infection

Wounds and Injuries

Pakistan
Karl Josef Franke, PD DR med

Completed

The Effect of Volitional Pursed-lips Breathing (PLB)

COPD

Germany
PD Dr. med. Margret Hund-Georgiadis
Swiss Tropical & Public Health Institute; Rehab Basel

Completed

Neurofeedback in Patients With Frontal Brain Lesions

Brain Lesion

Switzerland
Karolinska Institutet
Swedish Red Cross University College

Completed

Coping Effectiveness Training in Patients With Chronic Heart Failure

Heart Failure
Mead Johnson Nutrition
North Shore Research Institue

Completed

Early DHA Supplementation in Very Low Birth Weight Infants

Prematurity

United States
Helena Salminen
Medi GmbH & Co.KG

Completed

Treatment With a Spinal Orthosis Compared to Equipment Group Training and a Control Group

Back Pain | Osteoporosis | Elderly Women | Vertebral Fracture

Sweden
University of Toronto
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; The Physicians' Services Incorporated Foundation

Unknown

Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases

Cardiovascular Diseases | Stroke | Hypertension | Diabetes Mellitus, Type 2 | Gout | Metabolic Syndrome X

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy

Liver Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States

Cancer | Hematopoietic Stem Cell Transplantation

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Impact of "Teaching the Teachers" Concept on Global Education and Application of Hepatocellular Carcinoma Diagnosis Guidelines

Hepatocellular Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

MRI and Blood Biomarkers for the Prediction of Neurocognitive Decline Following Brain Radiation

Brain Neoplasm

United States

Clinical Trials Sponsored by MED Institute, Incorporated

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malaysia

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Rare Diseases

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