Search clinical trials for: Androgen Receptor

Total 19671 results

State University of New York at Buffalo
American Diabetes Association

Terminated

Hypogonadism in Young Men With Type 2 Diabetes

Type 2 Diabetes | Hypogonadotropic Hypogonadism

United States
University of California, San Diego
University of Virginia

Completed

Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)

PCOS

United States
Innocrin Pharmaceutical

Completed

CYP17 Lyase and Androgen Receptor Inhibitor Treatment With Seviteronel Trial (INO-VT-464-006; NCT02580448) (CLARITY-01)

Breast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer | Triple Negative Breast Cancer | Male Breast Cancer | ER+ Breast Cancer | Cancer of the Breast

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

Stage II Prostate Adenocarcinoma | Stage I Prostate Adenocarcinoma
University of Florida
Driver

Withdrawn

Prognostic Value of Androgen Receptor Expression and Mutations Within Oncogenes and Tumor Suppressor Genes in Patients Treated for High Risk Prostate Cancer With Proton Therapy (PRX32) (PRX32)

Prostate Cancer

United States
Medical University of South Carolina

Terminated

Bortezomib With or Without Hormone Therapy in Treating Patients With Relapsed Prostate Cancer

Prostate Cancer

United States
Medical University of Graz

Unknown

Analysis of Androgene Receptors Axis and DNA Damage Repair Genes in Patients With Prostate Cancer

Prostatic Neoplasms

Austria
Weill Medical College of Cornell University

Completed

Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration

Hypogonadism | Opioid-Related Disorders | Male Infertility

United States
University of California, San Diego

Completed

Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

United States
Innocrin Pharmaceutical
National Cancer Institute (NCI)

Completed

Oral VT-464 in Patients With Castration-Resistant Prostate Cancer Previously Treated With Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patients, and Men With ER Positive Breast Cancer

Prostate Cancer

United States
Havah Therapeutics Pty Ltd
GTx

Completed

Enobosarm and Anastrozole in Pre-menopausal Women With High Mammographic Breast Density

Mammographic Density

Australia
Aristotle University Of Thessaloniki

Completed

Androgen Receptor mRNA Expression is Positively Associated With Live Birth in Women Undergoing IVF Independently of the Type of Ovarian Response

Poor Ovarian Response | Androgen Receptor Gene Overexpression | Normal Responders | Bologna Criteria
NYU Langone Health
Novartis

Completed

Safety and Efficacy Studies of Panobinostat and Bicalutamide in Patients With Recurrent Prostate Cancer After Castration

Prostatic Neoplasms | Prostate Cancer

United States
Fudan University

Terminated

Bicalutamide as A Treatment in AR-positive Metastatic Triple-Negative Breast Cancer (mTNBC) Patients

Breast Cancer

China
Xu fei
Sun Yat-sen University

Unknown

Bicalutamide Plus Aromatase Inhibitors in ER(+)/AR(+)/HER2(-) Metastatic Breast Cancer (BETTER)

Breast Cancer

China
The Netherlands Cancer Institute
Astellas Pharma Inc

Completed

Dynamics of Androgen Receptor Genomics and Transcriptomics After Neoadjuvant Androgen Ablation (DARANA)

Prostate Cancer | Androgen Receptor Abnormal | DNA
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); Genentech, Inc.

Terminated

GDC-0941 and Cisplatin in Treating Patients With Androgen Receptor-Negative Triple Negative Metastatic Breast Cancer

Triple Negative Breast Cancer | Stage IV Breast Cancer | Triple-negative Breast Cancer | Recurrent Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Estrogen Receptor Negative Breast Cancer

United States
University of Washington

Completed

Study of Effectiveness of IMC-A12 Antibody Combined With Hormone Therapy Prior to Surgery to Treat Prostate Cancer

Prostate Cancer

United States
Mayo Clinic

Completed

Bicalutamide and Raloxifene in Treating Patients With Metastatic or Hormone-Refractory Prostate Cancer

Prostate Cancer | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
GlaxoSmithKline

Completed

Safety, Tolerability, Pharmacokinetic (PK), and Pharmacodynamic Study of GSK2881078 and Study to Evaluate the Effect of CYP3A4 Inhibition on PK of GSK2881078

Cachexia

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Development and Validation of in Vitro Cell-based Bioassays for Nuclear Receptor Activation

Hypogonadism | Estrogens | Androgens | Testosterone
Istituto Scientifico Romagnolo per lo Studio e...

Terminated

A Phase II Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT) (ARTT)

Estrogen Receptor Positive Breast Cancer | Androgen Receptor Gene Overexpression | Progesterone Receptor Positive Tumor | Metastatic Breastcancer | Estrogen Receptor Negative Neoplasm | Progesterone Receptor Negative Neoplasm

Italy
University of Florida

Withdrawn

The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia

Female Androgenetic Alopecia

United States
AstraZeneca

Completed

Phase I Open Label Dose Escalation Study to Investigate the Safety & Pharmacokinetics of AZD5312 in Patients With Androgen Receptor Tumors

Advanced Solid Tumours With Androgen Receptor Pathway as a Potential Factor

United Kingdom, United States
NYU Langone Health
Novartis

Terminated

Docetaxel (Taxotere) and Imatinib Mesylate (Gleevec) in Hormone Refractory Prostate Cancer

Prostatic Neoplasms | Prostate Cancer

United States
Lynn Henry

Completed

Observational Study to Evaluate Mechanisms of Aromatase Inhibitor Associated Musculoskeletal Symptoms

Breast Cancer | Arthralgia

United States
AstraZeneca

Completed

Open Label Prostate Cancer Study

Prostate Cancer

United Kingdom, Netherlands, United States
Cairo University

Completed

Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS

Polycystic Ovary Syndrome | Infertility

Egypt
University Hospital Inselspital, Berne
University of Zurich; University Hospital Muenster

Completed

Genetic Polymorphism of the Androgen Receptor-Gene and Sexual Function in Middle Aged Women (CAG-Libido)

Polymorphism, Genetic | Libido | Receptors, Androgen | Androgen Effect

Switzerland
Repros Therapeutics Inc.

Completed

The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)

Secondary Hypogonadism

United States
Toni Choueiri, MD

Withdrawn

STA-9090 in Castration-Resistant Prostate Cancer With Assessment of Androgen Receptor Pathway Signaling

Adenocarcinoma of the Prostate

United States
Repros Therapeutics Inc.

Completed

To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone

Secondary Hypogonadism

United States
Mahidol University

Unknown

Comparison of Body Weight Change During Contraception With Belara and Yasmin

Body Weight Changes

Thailand
Selmo Geber

Completed

Vascular Effect of Tibolone in the Brachial Artery (TDILA)

Menopause

Brazil
Federal University of Minas Gerais

Completed

Vascular Effect of Tibolone Versus Placebo Evaluated by Flow-mediated Dilatation of Brachial Artery

Flow-mediated Dilation Evaluation of the Brachial Artery

Brazil
The Alfred

Terminated

Investigation of Tibolone and Escitalopram in Perimenopausal Depression

Perimenopausal Depression

Australia
FDA Office of Orphan Products Development

Completed

Study of Albuterol and Oxandrolone in Patients With Facioscapulohumeral Dystrophy (FSHD)

Muscular Dystrophies

United States
National Cancer Institute (NCI)

Completed

R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer

Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
Tyumen State Medical Academy

Unknown

Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants

Hyperandrogenism | Polycystic Ovarian Syndrome | Menstrual Irregularities

Russian Federation
Duke University
Bristol-Myers Squibb

Terminated

Genomic Guided Therapy With Dasatinib or Nilutamide in Metastatic Castration-Resistant Prostate Cancer (ARS)

Prostate Cancer

United States
Repros Therapeutics Inc.

Completed

A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%

Secondary Hypogonadism

United States
Repros Therapeutics Inc.

Completed

A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%

Secondary Hypogonadism

United States
AndroScience Corp
Orient Europharma Co., Ltd.

Completed

Topical ASC-J9 Cream for Acne

Acne

United States, Taiwan
Repros Therapeutics Inc.

Completed

Normalization of Morning Testosterone Levels in Men With Secondary Hypogonadism

Secondary Hypogonadism

United States
University of Washington
National Institute on Aging (NIA); Solvay Pharmaceuticals

Completed

Hormone and Information Processing Study (HIP)

Mild Cognitive Impairment | Alzheimer's Disease

United States
Northwestern University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Metabolic Syndrome in PCOS: Precursors and Interventions

Polycystic Ovary Syndrome | Metabolic Syndrome

United States
Emotional Brain NY Inc.

Completed

Lybridos in Pre- and Postmenopausal Women With Hypoactive Sexual Desire Disorder Due to Maladaptive Activation of Sexual Inhibitory Systems

Hypoactive Sexual Desire Disorder

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Oral Microencapsulated Diindolylmethane in Treating Patients With Stage II-III Triple Negative, Androgen Receptor Positive Breast Cancer Who Have Undergone Chemotherapy and Surgery

Breast Cancer Female
GTx

Completed

Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy

Prostate Cancer | Osteoporosis | Fractures

United States, Mexico
GTx
Ipsen

Withdrawn

Efficacy and Safety Study of Toremifene Citrate for the Reduction in the Risk of New Bone Fracture Occurrences in Men With Prostate Cancer (TREAT2)

Risk of Bone Fracture Occurrences

United States

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