Search clinical trials for: Cellular models

Total 3754 results

Neogene Therapeutics, Inc.

Recruiting

A Study of NT-112 in HLA-C*08:02-Positive Adult Subjects With Unresectable, Advanced, and/ or Metastatic Solid Tumors Positive for the KRAS G12D Mutation

Endometrial Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Colorectal Carcinoma | Solid Tumor, Adult | KRAS G12D

United States
Centre for Addiction and Mental Health

Recruiting

A4i-O: A Platform for Complex Behavioral Health to Address OUD

Opioid-Related Disorders | Mental Health Wellness 1 | Mobile Phone Use | Comorbidities and Coexisting Conditions | Relationship, Professional Patient

Canada
Stanford University
Beth Israel Deaconess Medical Center; University of Minnesota

Recruiting

Physician Reasoning on Management Cases With Large Language Models

Clinical Decision-making

United States
Amsterdam UMC, location VUmc
University of Bergen; University of Oxford; Centre Hospitalier Universitaire... and other collaborators

Recruiting

Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression (VASCULAIDRETRO)

Peripheral Arterial Disease | Aneurysm Abdominal

Netherlands, United Kingdom, Finland, Germany, Portugal, Serbia
Inge Marie Svane
Adaptimmune

Not yet recruiting

To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma (ADP-TILIL7)

Melanoma | Melanoma Stage IV | Melanoma Stage III
Ugur Arzu Kulu

Recruiting

Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease

Endothelial Dysfunction | Graft Versus Host Disease | Acute Myeloid Leukemia, Adult

Turkey
Sonoma Biotherapeutics, Inc.

Recruiting

Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis (Regulate-RA)

Rheumatoid Arthritis

United States
Huda Salman

Recruiting

Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant

Acute Myeloid Leukemia

United States
Second Affiliated Hospital of Guangzhou Medical...

Not yet recruiting

GPC3/Mesothelin-CAR-γδT Cells Against Cancers

Lung Cancer | Mesothelioma | Pancreas Cancer | Liver Cancer | Solid Tumor, Adult | CAR-T Cell Therapy
Qilu Hospital of Shandong University

Recruiting

Development and Validation of Models to Predict Functional Cure in Patients With CHB After Peg-IFN Based Therapy

Hepatitis B, Chronic

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Randomized Pilot Study Evaluating Isopropyl Alcohol and UVC Rays in Disinfection of Cell Phones (SaniPhone)

Cross Infection

Italy
AstraZeneca

Not yet recruiting

LTFU for All Cell and Gene Therapy Studies (LOCUS)

Hepatocellular Carcinoma | Prostate Cancer

United States
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Subjects With Refractory Generalized Myasthenia Gravis

Generalized Myasthenia Gravis | Myasthenia Gravis
Ourotech, Inc.
Barts & The London NHS Trust; Imperial College Healthcare NHS Trust; Hampshire... and other collaborators

Recruiting

Prospective Evaluation of AI R&D Tool for Patient Stratification - MoA Evaluation in Triple Negative Breast Cancer (PEAR-MET) (PEAR-MET)

Breast Cancer | Triple Negative Breast Cancer

United Kingdom
First Affiliated Hospital, Sun Yat-Sen University

Recruiting

Autologous Epidermal Cell Treat for Nonhealing Postoperative Wound

Healing Wound

China
University of Massachusetts, Worcester
Intra-Cellular Therapies, Inc.

Recruiting

Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia

Schizophrenia | Schizo Affective Disorder

United States
invIOs GmbH

Recruiting

PBMC-based Leukocyte Immunotherapy (PALINDROM)

Advanced Solid Tumor

Austria
Merck Sharp & Dohme LLC

Recruiting

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

Non-small Cell Lung Cancer (NSCLC)

China, Australia, United States, Turkey, Chile, Taiwan, Denmark, France, Spain, Argentina, Italy, Netherlands, Thailand, Korea, Republic of
Keele University
Norfolk and Norwich University Hospitals NHS Foundation Trust; University of... and other collaborators

Recruiting

Developing Allogeneic Musculoskeletal Therapies

Osteoarthritis

United Kingdom
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
University of Trieste; IRCCS Fondazione Stella Maris; CNR Institute of Neuroscience...

Recruiting

Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy) (GAPsy)

Healthy | Depression, Anxiety

Italy
Affiliated Hospital of Guangdong Medical University

Recruiting

Prediction Models for Risk Score and Prognosis of Intraoperatively Acquired Pressure Injury in Surgical Patients

Pressure Ulcer | Clinical Outcome | Predictive Models | Surgical Patient

China
Alcon Research

Recruiting

Evaluation of Long-term Safety and Performance of PanOptix Intraocular Lens (IOLs)

Presbyopia | Astigmatism | Aphakia

Spain
Fondazione IRCCS San Gerardo dei Tintori
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; A.O. Ospedale Papa... and other collaborators

Recruiting

Mesenchymal Stromal Cells for Traumatic Brain Injury (MATRIx)

Traumatic Brain Injury With Loss of Consciousness

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
IRCCS Centro Neurolesi "Bonino-Pulejo"; Fondazione Don Carlo Gnocchi Onlus; Istituto... and other collaborators

Recruiting

Modeling Outcome in Patients With Acquired Brain Injuries (MOF-ABI)

Brain Injuries

Italy
National Cancer Institute (NCI)

Not yet recruiting

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as Small Cell, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile Cancer

Squamous Cell Carcinoma of the Penis | Renal Medullary Carcinoma | Squamous Cell Carcinoma of the Bladder | Small Cell Carcinoma of the Bladder | Small Cell Carcinoma of the Urinary Tract | Squamous Cell Carcinoma of the Urinary Tract | Primary Adenocarcinoma of the Bladder | Primary Adenocarcinoma...

United States
Assistance Publique - Hôpitaux de Paris
Infectious Diseases Models for Innovative Therapies center

Not yet recruiting

Association of Dysbiosis and Immune Response in Bronchiolitis in Under 12 Months -Old Infants (BRONCHOBIOTE)

Bronchiolitis

France
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Autologous CAR-T Cells Targeting B7-H3 in PDAC

Pancreas Cancer | Relapse | Resistant Cancer

United States
Novartis Pharmaceuticals

Recruiting

Long-term Follow-up (LTFU) of Patients Treated With Genome-edited Autologous Hematopoietic Stem and Progenitor Cells (HSPC)

Sickle Cell Disease

United States
Cabaletta Bio

Recruiting

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy

Idiopathic Inflammatory Myopathy | Dermatomyositis | Immune-Mediated Necrotizing Myopathy | Anti-Synthetase Syndrome

United States
Fudan University
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Perioperative Sintilimab and Chemotherapy in Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Single Arm Clinical Study on the Safety and Efficacy of Personalized KSX01-TCRT in Patients With Advanced Solid Tumors

Refractory Solid Tumors | Relapsed Solid Tumors

China
Dushu Lake Hospital Affiliated to Soochow University

Recruiting

Natural Killer (NK) Cells (XS005) Injection Combined With Stupp Regimen for Adjuvant Chemotherapy in Subjects With Primary Glioblastoma(GBM)

Glioblastoma | GBM

China
Fu Jen Catholic University

Recruiting

Utilizing 3D Printed Personalized Aortic Lesion Models in Preoperative Assessment

Aortic Aneurysm

Taiwan
Cairo University
Future University in Egypt

Recruiting

Evaluation of Artificial Intelligence Models for Diagnosis of Anterior Open Bite Malocclusion

Artificial Intelligence | Open Bite

Egypt
Stanford University
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
Merck Sharp & Dohme LLC
GOG Foundation; European Network for Gynaecological Oncological Trial groups(ENGOT)

Recruiting

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

Endometrial Cancer

Poland, United States, Canada, Australia, Israel, Korea, Republic of, Spain, Chile, France, Puerto Rico, Greece, Netherlands, Norway, Singapore, Switzerland, Argentina, Austria, Belgium, Czechia, Denmark, Finland, Malaysia, Sweden, Italy and more
Memorial Sloan Kettering Cancer Center

Recruiting

A Study to Identify Barriers to Cellular Therapies for People With Plasma Cell Disorders

Multiple Myeloma

United States
Xuzhou Medical University

Recruiting

Administration of Anti Tim-3/CD123 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia (rr/AML)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

China
Arcturus Therapeutics, Inc.
Novotech (Australia) Pty Limited; Seqirus

Recruiting

Safety and Immunogenicity First-in-human Dose-ranging Study of Self-Amplifying RNA Seasonal Influenza Vaccine in Adults

Influenza, Human

Australia
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

Breast Neoplasms

China
IRCCS San Raffaele

Recruiting

Development of New Personalised 3D Preclinical Models of Pancreatic Neuroendocrine Tumours (3DPanNET)

Pancreatic Neuroendocrine Tumor

Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms

China
Juno Therapeutics, Inc., a Bristol-Myers Squibb...

Recruiting

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States, Canada
Johns Hopkins University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Not yet recruiting

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis (BATON)

Osteonecrosis of the Femoral Head | Avascular Necrosis of the Femoral Head

United States
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Real World Experience With Mogamulizumab in the Treatment of Cutaneous T-cell Lymphoma (FIL_MOGA)

Cutaneous T Cell Lymphoma | Cutaneous T-Cell Lymphoma/Mycosis Fungoides | Cutaneous T-Cell Lymphoma/Sezary Syndrome

Italy
Centro di Riferimento Oncologico - Aviano

Recruiting

A Study to Develop Molecular Integrated Predictive Models of Breast Radio-toxicity (Precise-RTox) ((Precise-RTox))

Breast Cancer

Italy
Tulane University
Johns Hopkins Bloomberg School of Public Health; Universidad Peruana Cayetano... and other collaborators

Not yet recruiting

Diagnostic Innovations for Pediatric Tuberculosis in Bolivia

Tuberculosis
Centre Hospitalier Universitaire de Nice

Recruiting

Tirbanubulin (Klisiry®) in the Treatment of Basal Cell Carcinoma (Tirbaso)

Cell Carcinoma

France
Catharina Ziekenhuis Eindhoven
Maastricht University Medical Center; The Netherlands Cancer Institute; Maxima... and other collaborators

Not yet recruiting

Implementation of Up-front ctDNA Into Lung Cancer Care and Development of Liquid Biopsy-based Decision Support Models - LM² Study (LM2)

Lung Cancer

Netherlands

Search clinical trials for: Cellular models

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