Search clinical trials for: Circulating DNA methylation biomarker

Total 17729 results

Gene Solutions
University of Medicine and Pharmacy at Ho Chi Minh City

Recruiting

Clinical Validation of an MCED Test in Symptomatic Populations (K-ACCELERATE) (K-ACCELERATE)

Cancer, Breast | Cancer, Lung | Cancer Colon | Cancer, Gastric | Cancer, Liver

Vietnam
University of Rome G. Marconi
University of Bologna; University of the Italian Switzerland

Not yet recruiting

Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health (MOTHERS)

Stress | Insomnia | Postpartum Depression

Italy
University of Aarhus
Aarhus University Hospital

Recruiting

Circulating Tumor DNA in Peripheral T-cell Lymphomas (CIRCULATE)

Peripheral T-cell Lymphoma | NK/T-Cell Lymphoma

Denmark
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; CGenetix

Not yet recruiting

Detection of Circulating Kidney DNA in Kidney Transplant Patients Facing an Episode of Graft Rejection (DART-RREGREF)

Kidney Transplant Patients Eligible for a Solid Biopsy
University Hospital, Basel, Switzerland

Not yet recruiting

Targeted Radionuclide Therapy in Metastatic Prostate Cancer Using a New PSMA Ligand Radiolabelled With Terbium-161 (161Tb-SibuDAB) - Dose Identification/Escalation Phase Ia/b Study (PROGNOSTICS)

Castration-resistant Prostate Cancer

Switzerland
Ohio State University Comprehensive Cancer Center

Recruiting

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

United States
Zhujiang Hospital

Not yet recruiting

Value of Dynamic Monitoring of Early Recurrence of Hepatocellular Carcinoma After Radical Resection Based on CTCS

Recurrence | Hepatocellular Carcinoma | Surgery | Circulating Tumor Cell

China
City of Hope Medical Center

Recruiting

Stage II/III Colorectal Cancer Recurrence (CENSURE)

Colorectal Cancer | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Recurrent

Spain, United States, China
Mayo Clinic

Recruiting

Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Central Arkansas Veterans Healthcare System
United States Department of Defense; University of Arkansas

Recruiting

DNA Methylation Markers in Veterans Exposed to Open Burn Pits

Open Burn Pit Exposure

United States
Oslo University Hospital

Recruiting

Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy

Metastatic Colorectal Cancer | Cholangiocarcinoma | Pancreas Adenocarcinoma

Norway
Peking University Third Hospital
Beijing Tsinghua Changgeng Hospital

Recruiting

Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE) (ECCBILE)

Bile Duct Cancer | Pancreas Cancer | Biliary Stricture

China
Interni hematologicka klinika FNKV
Charles University, Czech Republic; University Hospital Olomouc; General University... and other collaborators

Recruiting

Prognostic Significance of ctDNA in HL

Prognostic Cancer Model

Czechia
WomenX Biotech Limited
Hong Kong Science and Technology Parks Corporation

Recruiting

Non-invasive Biomarker Discovery for Pre-cervical or/and Cervical Cancer-HPV DNA and Other Biomarkers in Urine

Cervical Cancer

Hong Kong
Yung NA
Queen Mary Hospital, Hong Kong; Pamela Youde Nethersole Eastern Hospital

Recruiting

Surveillance of the Genetic Signature in Circulating Tumor DNA for Guiding Adjuvant Chemotherapy in Urothelial Carcinoma: A Pilot Randomized Controlled Trial

Muscle-Invasive Bladder Carcinoma | Muscle Invasive Bladder Urothelial Carcinoma

Hong Kong
Pennington Biomedical Research Center

Recruiting

Diet-Induced Changes in GEnetic Material (DIG 'EM)

Body Weight | Diet, Healthy | Metabolic Disturbance

United States
Sunnybrook Health Sciences Centre
MOUNT SINAI HOSPITAL; Princess Margaret Hospital, Canada; Trillium Health Partners

Recruiting

MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer

Breast Cancer

Canada
Assistance Publique - Hôpitaux de Paris

Recruiting

Studies of Phenotypic and Functional Characteristics of Circulating Neutrophil Subpopulations in Patients With Lung Cancer (PNN-CP)

Lung Cancer

France
Meyer Children's Hospital IRCCS
Careggi Hospital; University of Florence

Not yet recruiting

The Epigenomic Signature of Eosinophilic Granulomatosis With Polyangiitis (EPI-EGPA)

Eosinophilic Granulomatosis With Polyangiitis
Yonsei University

Recruiting

A Prospective, Multi-center Clinical Study to Establish Multi-Cancer Early Detection Platform Through the Analysis of Whole Genome Sequencing of Circulating DNA in Cancer Patients and Healthy Volunteers

Healthy Volunteer | Invasive Cancer

Korea, Republic of
Shanghai Weihe Medical Laboratory Co., Ltd.
Peking University People's Hospital

Recruiting

a PROspective Case Control Study to Develop and Validate a Blood Test FOr mUlti-caNcers Early Detection（PROFOUND） (PROFOUND)

Cancer

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

DNA Methylation Combined With Artificial Intelligence Imaging to Identify Lung Nodules (MAGIC)

Lung Cancer Diagnosis

China
Sun Yat-sen University
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer (MIRROR)

Colorectal Cancer

China
University Hospital, Strasbourg, France

Recruiting

Identification of Y Chromosome From Free Circulating DNA in Patients With Turner Syndrome (Turner-Ylc)

Turner Syndrome

France
University Hospital, Caen

Recruiting

Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAs (GliomiR)

Glioma, Malignant

France
University of Wisconsin, Madison

Recruiting

Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients

Melanoma | Unresectable Melanoma | Melanoma Stage IV | Melanoma Stage III

United States
Institut Curie
Zionexa

Recruiting

ECLECTIC: EstroTEP and Circulating Biomarkers for ER-positive HER2-negative Metastatic Breast Cancer Patients (ECLECTIC)

Breast Carcinoma

France
Universitaire Ziekenhuizen KU Leuven

Recruiting

Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease (NICO)

Neurodevelopmental Disorders | Biomarkers | Congenital Heart Disease | Electroencephalography | Near-Infrared Spectroscopy

Belgium
Institut Curie
Hoffmann-La Roche

Recruiting

Tiragolumab, Atezolizumab and Chemotherapy in Triple Negative Breast Cancer (SKYLINE)

Triple Negative Breast Cancer

France
Shanghai East Hospital

Not yet recruiting

Circulating Tumor DNA Guided Adjuvant Chemotherapy for Biliary Tract Carcinoma

Biliary Tract Cancer

China
Gene Solutions

Recruiting

Analysis of Circulating Tumor DNA Dynamics to Predict and Monitor Response to TKI in Patients With Advanced NSCLC.

Non Small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Stage IIIC Non-Small Cell Lung Cancer | Tyrosine Kinase Inhibitors

Vietnam
Zhujiang Hospital

Recruiting

Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Longitudinal Monitoring MRD Based on ctDNA

Hepatocellular Carcinoma Resectable

China
Centre Henri Becquerel

Not yet recruiting

Kinetics of Circulating Tumor DNA in Lymphoma Treated by Immuno-chemotherapy (LYMPHO-CLEAR)

Diffuse Large B Cell Lymphoma

France
Sun Yat-sen University
The First Affiliated Hospital of Anhui Medical University; Peking University... and other collaborators

Recruiting

PaCIFiC-CUP Classifies Cancer of Unknown Primary

Unknown Primary Tumors | DNA Methylation

China
Duke University
Memorial Sloan Kettering Cancer Center; University of Wisconsin, Madison

Recruiting

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials (ARCTIC)

Prostate Cancer | Castration-resistant Prostate Cancer | Prostate Adenocarcinoma | Prostate Cancer Metastatic

United States
University Medical Center Groningen
Centre Hospitalier Universitaire de Nice; LungenClinic Grosshansdorf

Recruiting

Clinical Validation and Benchmarking of Top Performing ctDNA Diagnostics - Stage III NSCLC (MRD-LUNG)

Lung Cancer Stage III

France, Germany, Netherlands
Claus Lindbjerg Andersen
Karolinska Institutet; Medical University of Graz; University of Aarhus; Universitätsklinikum... and other collaborators

Recruiting

Clinical Validation and Benchmarking of Top Performing ctDNA Diagnostics - Colorectal Cancer

Colorectal Cancer Stage III | Liver Metastasis Colon Cancer

Germany, Denmark, Austria, France, Sweden
Centre Henri Becquerel

Not yet recruiting

Circulating Tumor DNA Sequencing in Patients With Peripheral T-cell Lymphomas (PTCL-SEQ)

Peripheral T Cell Lymphoma

France
University of Maryland, Baltimore

Recruiting

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) (SAVAL)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Oropharynx Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Oropharynx Squamous Cell Carcinoma

United States
Gene Solutions

Recruiting

Investigate the Prognostic and Predictive Value of ctDNA During Neoadjuvant Chemotherapy for Breast Cancer.

Triple Negative Breast Cancer | HER2-positive Breast Cancer | Stage II Breast Cancer | Breast Cancer Female | Stage III Breast Cancer

Vietnam
University of Aarhus
Aarhus University Hospital

Recruiting

DANISH.MRD: Danish Assessment of Minimal Residual Disease by Liquid Biopsies (DANISH_MRD)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage I

Denmark
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

SEQUENTIAL PROFILING OF TUMOR-DERIVED CIRCULATING CELL-FREE DNA (ctDNA) IN ADVANCED OVARIAN CANCER PATIENTS (SPEED)

Ovarian Cancer

Italy
University of Wisconsin, Madison

Recruiting

Biomarkers to Detect Endocrine Therapy Resistance

Breast Cancer | Metastatic Cancer | Lobular Breast Carcinoma

United States
Helsinki University Central Hospital

Recruiting

Biomarkers for Diagnosis, Prognosis, and Targeted Therapy After Heart Transplantation (EMBIO)

Heart Transplant Rejection

Finland
Invitae Corporation
National Cancer Center Hospital East

Recruiting

Multicenter Study of Circulating Tumor DNA in Patients With Pancreatic Cancer Using a Personalized Panel (ARTEMIS-PC)

Pancreatic Cancer

Japan
Hospital Clinico Universitario de Santiago
Hospital Arquitecto Marcide

Not yet recruiting

Nutritional Intervention-induced Weight Loss During the Oncological Treatment of Obesity-related Breast Cancer (NUTOBREST)

Obesity | Breast Cancer | Weight Change, Body | Epigenetic Disorder
Air Force Military Medical University, China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; The First Affiliated... and other collaborators

Recruiting

Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreas Cancer | Liver Cancer | Esophagus Cancer | Cancer Diagnosis | LungCancer

China
Erasmus Medical Center

Not yet recruiting

Can we Use a Simple Blood Test to Reduce Unnecessary Adverse Effects From Radiotherapy by Timely Identification of Radiotherapy-resistant Rectal Cancers? MeD-Seq Rectal Study

Pathological Response Rate, Circulating Tumour DNA
Liverpool University Hospitals NHS Foundation Trust
Kidney Research United Kingdom

Not yet recruiting

Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients (HLA-AB)

Frailty | Kidney Transplant Rejection | Renal Transplant | Diagnosis | Kidney Transplant; Complications | Kidney Transplant | Renal Transplant Failure | Transplant Dysfunction

United Kingdom
Weill Medical College of Cornell University
National Cancer Institute (NCI); University of Sao Paulo; H. Lee Moffitt Cancer... and other collaborators

Recruiting

Optimization of Cervical Cancer Screening Among Women Living With HIV in Latin American Countries

HIV Infections | Cervix Cancer | HPV Infection | Cervical High Grade Squamous Intraepithelial Lesion

Brazil, Mexico

Search clinical trials for: Circulating DNA methylation biomarker

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