Search clinical trials for: Double Blinded Randomized Controlled

Total 19789 results

shifeng Lou

Recruiting

A Randomized Controlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLH

Hemophagocytic Syndrome

China
Cassiopea SpA
ICON Clinical Research; Canfield Scientific Inc.; Ergomed PLC; Pharmapace Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss (SCALP2) (SCALP2)

Alopecia, Androgenetic

Germany, United States, Poland
Cassiopea SpA
ICON Clinical Research; Canfield Scientific Inc.; Ergomed PLC; Pharmapace Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss (SCALP1)

Alopecia, Androgenetic

United States, Georgia
Xueli Cai

Recruiting

Stent Implantation Versus Balloon Dilation for Acute Anterior Circulation Tandem Occlusion (START)

Stroke | Thrombectomy | Tandem Occlusion

China
Chinook Therapeutics, Inc.

Recruiting

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy (ASSIST)

Immunoglobulin A Nephropathy | IgA Nephropathy

Spain, United States, Australia, Korea, Republic of, Brazil, Malaysia
Maimonides Medical Center

Recruiting

Vaginal Cuff Infiltration With Liposomal Bupivacaine for Pain Relief: A Double Blind, Randomized Controlled Trial

Postoperative Pain

United States
Salim S. Hayek

Recruiting

A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study to Determine the Safety and Effectiveness of Azeliragon in the Treatment of Patients Hospitalized for Coronavirus Disease 2019 (COVID-19) or Pneumonia

COVID-19

United States
Eva Pharma
MARC-CRO

Recruiting

Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)

Polyneuropathy, Diabetic

Egypt
Tan Tock Seng Hospital
National Neuroscience Institute; Nanyang Polytechnic

Recruiting

Immersive Virtual Reality for Dual-task Training in Older Adults With Mild Cognitive Impairment: A Randomized Controlled Trial

Mild Cognitive Impairment

Singapore
Vastra Gotaland Region
Sahlgrenska University Hospital, Sweden; The Gothenburg Society of Medicine; Åke... and other collaborators

Not yet recruiting

Treatment Study in Patients Treated With Both Insulin & Hydrocortisone (INSCORT)

Diabetes Mellitus | Adrenal Insufficiency | Polyglandular Autoimmune Syndrome

Sweden
Anthos Therapeutics, Inc.

Recruiting

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76) (LILAC-TIMI 76)

Atrial Fibrillation (AF)

United States, Canada, Israel, Japan, China, Brazil, Chile, United Kingdom, Bulgaria, Germany, Hungary, Italy, Poland, Romania, Spain, Czechia, Latvia, Mexico, India, Estonia
West Virginia University
University of Florida; Tourette Association of America

Recruiting

Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study (STOP-TIC)

Tourette Syndrome

United States
University of Colorado, Denver

Recruiting

A Randomized Controlled Trial of No Strings Intrauterine Device (IUD) Removal Techniques

IUD Threads Not Visible | IUD Removal Complication

United States
Guangdong Raynovent Biotech Co., Ltd

Recruiting

A Randomized, Double-blind, Placebo-controlled Study of ZSP1601 in Adult Subjects With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

China
Peking Union Medical College Hospital

Not yet recruiting

Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness

COVID-19 Respiratory Infection
Queen Mary Hospital, Hong Kong

Not yet recruiting

An Randomized Double Blind Controlled Trial of niPGT-A in Women With RPL (niPGTA)

Infertility

Hong Kong
RedDress Ltd.

Recruiting

A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas

Anal Fistula

United States, Israel
University of Minnesota

Recruiting

Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Neuropathic Pain | Spinal Cord Injuries

United States
Oslo University Hospital
Vestre VikenHF Kongsberg Sykehus

Recruiting

Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial (AFFECT2)

Opioid Use | Affective Symptoms

Norway
Women's Hospital School Of Medicine Zhejiang University
ORGANON (SHANGHAI) PHARMACEUTICAL TECHNOLOGY CO., LTD.

Not yet recruiting

Comparison of Clinical Outcomes in Fresh Cycle With Single Blastocyst Stage and Double Cleavage-stage Embryos: a Single-center, Non-blind, Randomized Controlled Study

Infertility, Female
Ain Shams University

Recruiting

Effects of Curcumin on Inflammation and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

Pediatric Patients Having Renal Failure and on Regular Hemodialysis

Egypt
University Hospital, Tours

Recruiting

Evaluation of Efficacy and Safety of Rituximab in Patients With Progressive Interstitial Lung Disease (ILD) With Inflammatory Component: a Multicentre Double-blind Placebo-controlled Randomized Trial (EvER-ILD2)

Lung Diseases

France
Beijing Tiantan Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy of Pentoxifylline on Cerebrovascular Function in Patients With Cerebral Small Vessel Disease(PERFORM) (PERFORM)

Cerebral Small Vessel Diseases

China
Luzerner Kantonsspital
Stryker SA; Kantonsspital Obwalden; Spital Schwyz

Not yet recruiting

Double Plating Versus Single Plating Techniques in Midshaft Clavicle Fractures

Clavicle Fracture
EpicentRx, Inc.
Sciclone Pharmaceuticals (China) Co., Ltd.

Recruiting

A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Doublet in Small Cell Lung Cancer (REPLATINUM)

Carcinoma, Small Cell Lung

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

The Effect of PHGG-rich Enteral Nutrition to on the Infection in Liver Transplant Recipients: A Prospective, Double-blind, Randomized Controlled Study

Infections
PlasFree Ltd.

Recruiting

A Pre-market, Multi-center, International, Double-blind, Randomized, Two-arms, Controlled, Prospective Clinical Investigation Assessing the Safety and Performance of a Medical Device (ClearPlasma™) for the Treatment of Patients Undergoing Coronary Artery Bypass or Valve Replacement

Bleeding | Bypass Complication | Valve Replacement

Israel, Czechia, Poland
AriBio Co., Ltd.

Recruiting

Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD)

Alzheimer Disease

Korea, Republic of, United States, United Kingdom
Parnassia Addiction Research Centre
Radboud University Medical Center; Columbia University; Academisch Medisch Centrum... and other collaborators

Not yet recruiting

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Cocaine Use Disorder
Stephenson Eye Associates

Recruiting

A Randomized, Controlled, Double-masked, Investigator-initiated Trial to Evaluate Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal Spray (TSUNAMI)

Dry Eye Disease

United States
Sichuan Cancer Hospital and Research Institute

Recruiting

Nituzumab (Taixinsheng ®） A Prospective, Randomized, Double-blind, Placebo-controlled, Multicenter Phase II Clinical Study on the Efficacy and Safety of Combined Induction Chemotherapy for Locally Advanced Nasopharyngeal Carcinomatreatment of Locally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Shanghai Zhimeng Biopharma, Inc.
Tigermed Consulting Co., Ltd

Recruiting

A Study to Evaluate the Efficacy and Safety of ZM-H1505R in Combination With ETV Compared With ETV Monotherapy in Patients With CHB

Hepatitis B, Chronic

China
LUCINDA BATEMAN, MD
Endourage, LLC

Not yet recruiting

Double-Blind Randomized Placebo-Controlled Trial of a Proprietary Full Hemp Flower Formulation for Long COVID

Post-acute COVID-19 Syndrome

United States
Tanta University

Not yet recruiting

Quadratus Lumborum Versus Transversus Abdominis Plane Block Versus Caudal Block for Postoperative Analgesia After Pediatric Inguinal Hernia : Double-Blinded Randomized Trial

Postoperative Pain | Inguinal Hernia | Caudal Block | Quadratus Lumborum Block | Transversus Abdominis Plane Block
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Buddhist Tzu Chi General Hospital

Not yet recruiting

Effect of Jing Si Herbal Tea on Inflammation in Patients With Cardiovascular Disease

Cardiovascular Diseases | Inflammatory Response | Gut Microbiome | Herbal Medicine | Life Quality | Trimethylamine N-oxide
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

Colorectal Cancer | Lynch Syndrome | T Cells

United States
Wangjing Hospital, China Academy of Chinese Medical...

Not yet recruiting

The Study of Chinese Medicine for the Treatment of Primary Osteoporosis

Primary Osteoporosis

China
Wex Pharmaceuticals Inc.

Recruiting

A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

Chemotherapy-induced Peripheral Neuropathy | Chemotherapy-induced Neuropathic Pain

United States
Chengdu Easton Biopharmaceuticals Co,Ltd

Recruiting

A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Clinical Efficacy and Safety of Yogliptin Tablets

Type 2 Diabetes

China
Beijing Tiantan Hospital
GrandPharma (China) Co., Ltd.

Recruiting

Study on Tirofiban With Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY)

Branch Atheromatous Disease

China
Jagiellonian University
Vanderbilt University Medical Center; Population Health Research Institute

Recruiting

Ivabradine for Prevention of Myocardial Injury After Noncardiac Surgery Trial (PREVENT-MINS) (PREVENT-MINS)

Myocardial Ischemia | Myocardial Injury After Noncardiac Surgery (MINS)

Poland
Marinus Pharmaceuticals

Not yet recruiting

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

CDKL5 Deficiency Disorder
Chang Gung Memorial Hospital
Scientis Pharma SA

Recruiting

Efficacy and Safety of Topical Cysteamine for Postinflammatory Hyperpigmentation

Hyperpigmentation; Postinflammatory

Taiwan
Palvella Therapeutics, Inc.

Recruiting

A Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia Congenita (VAPAUS)

Pachyonychia Congenita

United States, United Kingdom
Mayo Clinic

Recruiting

Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy

Multiple System Atrophy

United States
Umeå University
Region Västerbotten

Recruiting

Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture (DAICY)

Femoral Neck Fractures | Prosthetic Infection

Sweden
Cairo University

Recruiting

Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study

Critical Illness | Analgesia | Sedation | Mechanical Ventilation

Egypt
Ratan K. Chaudhuri

Recruiting

Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bakuchiol and Ethyl Linoleate on Acne

Acne Vulgaris

United Kingdom

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