Search clinical trials for: High comorbidity burden

Total 21593 results

Shanghai Mental Health Center

Not yet recruiting

Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder

Gambling Disorder

China
Pamukkale University

Not yet recruiting

Sympatholytic Effects of High Thoracic Erector Spinae Plane Block: Changes in Optic Nerve Sheath Diameter

Complex Regional Pain Syndromes
King's College Hospital NHS Trust
King's College London

Not yet recruiting

ESCALATion of Medical Therapy Following Multimodality Plaque Evaluation in High-risk Chronic Coronary Syndromes (ESCALATE)

Coronary Artery Disease
Sun Yat-sen University

Not yet recruiting

Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC

Hepatocellular Carcinoma | Beyond Milan Criteria
Ruijin Hospital

Recruiting

A Trial on the Recurrence Free Survival Rate of Type I AIP With High-risk of Recurrence

Type 1 AIP

China
Duke University

Not yet recruiting

A Phase 1 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of JCXH-211 (SElf-Replicating RNA IL-12) Intratumoral Injection in Patients With Recurrent or Progressive High-Grade Glioma (SERIL)

Recurrent or Progressive High-grade Glioma
Quiropraxia y Equilibrio

Not yet recruiting

High-intensity Laser Therapy and Stretching Exercises for Chronic Non-specific Neck Pain

Chronic Non-specific Neck Pain

Chile
Shivanka Research, LLC
Eric Solutions LLC; Clinexcel Research, Ahmedabad, India

Not yet recruiting

SAD Study to Evaluate Safety, Tolerability, and Pharmacokinetic Profile of KSHN001126 in Healthy Post-Menopausal Females

Healthy Postmenopausal Women

United States, India
University Hospital, Lille

Recruiting

Changes in Attentional Control After a Focal Seizure. (ATTENTIONEPIF)

Temporal Lobe Epilepsy | Frontal Lobe Epilepsy | Others Subtypes

France
Swiss GO Trial Group
Tumor Profiler Center Switzerland

Not yet recruiting

OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy (OVPrecision)

Fallopian Tube Neoplasms | Ovarian Neoplasm Epithelial | High-grade Serous Ovarian Carcinoma (HGSOC) | Ovarian Endometrioid Carcinoma

Switzerland
Centre Hospitalier Universitaire Dijon

Not yet recruiting

The Benefits of Long-read High-throughput Genomic Sequencing for the Causal Diagnosis of Cerebellar Ataxias (ALICA)

Cerebellar Ataxias

France
Shu-Cheng Lin

Recruiting

Effect of Vegetable and Fruit Enzyme Supplementation on Muscle Activation, Aerobic Capacity, and Blood Biochemical Parameters After High-Intensity Interval Exercise: Feasibility Study of Exercise Design With Exergaming

Overtraining Syndrome

Taiwan
Nausicaa Medical
Clin-Experts

Not yet recruiting

Prevention of Pressure Ulcers in Patients at Medium to High Risk of Pressure Ulcers Using the R'GO SOINS Overlay Mattress (PRESERVE)

Pressure Ulcer

France
Universidade Federal do Rio de Janeiro

Recruiting

Extremes of Respiratory Effort in Weaning Failure From Mechanical Ventilation: a Prospective Observational Study

Weaning Failure | Mechanical Ventilation Pressure High

Brazil
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA (DURVASCC)

Extrapulmonary Small Cell Carcinoma

Italy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
EMD Serono Research & Development Institute, Inc.

Not yet recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

United States, Germany
Medical College of Wisconsin

Recruiting

Effects of an Air Bolus on Primary Peristalsis

Deglutition Disorders

United States
Fundacion Clinic per a la Recerca Biomedica

Not yet recruiting

Imlifidase in Living Donor Renal Transplantation Highly Sensitized Recipients (LIVEDES)

Kidney Transplant Candidates
SpinChip Diagnostics ASA
CTC Clinical Trial Consultants AB; Scandinavian Contract Research Organization

Recruiting

SpinChip Hs-cTnI Determination of the 99th Percentile URL (HEAT-3)

Acute Myocardial Infarction

Sweden
Diakonhjemmet Hospital

Not yet recruiting

A Digital Exercise Intervention in Patients With Spondyloarthritis (SPARK)

Exercise | Spondyloarthritis

Norway
Riphah International University

Recruiting

Effects of Sprint Interval Training Versus Arabic Exercises BMI

PCOS

Pakistan
Central Hospital, Nancy, France

Not yet recruiting

Comparison of Changes in Tumor Burden in 68Ga-PSMA-11 PET/CT and 177Lu-PSMA SPECT/CT in Metastatic Castration-resistant Prostate Cancer (PROLUT)

Prostate Cancer Metastatic

France
Samsung Medical Center

Recruiting

Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Patients With High - Risk Localized Prostate Cancer (DESAR-H) (DESAR-H)

High Risk Prostate Carcinoma

Korea, Republic of
University of Melbourne
Monash University; University of Adelaide; University of Sydney; The University... and other collaborators

Not yet recruiting

PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] (PLATIPUS)

Preterm Birth
H. Lee Moffitt Cancer Center and Research Institute
EMD Serono Research & Development Institute, Inc.

Not yet recruiting

Study to Assess Xevinapant in Preoperative Subjects With Recurrent High-Grade Glioma (rHGG)

Recurrent High-grade Glioma

United States
University of Bonn

Recruiting

Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic (GCAIO)

Giant Cell Arteritis | Polymyalgia Rheumatica

Germany
The Taylor Collaboration
Wilma Chan Highland Hospital Campus

Not yet recruiting

Non-Invasive Distractor During Knee Arthroscopy

Knee Arthritis | Knee Arthropathy
Kafkas University

Not yet recruiting

The Effect of Stress Ball on COPD Patients Receiving Noninvasive Mechanical Ventilation Support

COPD | Mechanical Ventilation Pressure High

Turkey
Lee's Pharmaceutical Limited

Not yet recruiting

Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer

Cervical Cancer
Oregon Health and Science University
The Hart Family Foundation

Recruiting

Support Via Technology: Living and Learning With Advancing Dementia-REVISED (STELLA-R)

Caregiver Burden

United States
Seoul St. Mary's Hospital

Not yet recruiting

Comparison of Clinical Outcomes According to High-protein Provision in Critically Ill Patients After Abdominal Surgery

Protein Malnutrition

Korea, Republic of
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-Component Interventions on High Risk COPD Population (POPMIX-COPD)

Chronic Obstructive Pulmonary Disease | Multimorbidity | Population Medicine
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-Component Interventions on High-Risk COPD Smokers (POPMIX-Smoking)

Smoking Reduction | Tobacco Use Cessation | Multimorbidity
Ruijin Hospital

Not yet recruiting

The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-component Interventions on Populations With Mental Health Symptoms and High-risk COPD (POPMIX-MH)

Multimorbidity | Mental Health Issue | Multi-component Interventions
Ruijin Hospital

Not yet recruiting

The Efficacy of Allo-HSCT in ND HR-CBF-AML

Acute Myeloid Leukemia

China
Abramson Cancer Center at Penn Medicine
Genmab

Not yet recruiting

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

Lymphoma, Non-Hodgkin | High-grade B-cell Lymphoma | Refractory Diffuse Large B-cell Lymphoma | Relapsed Diffuse Large B Cell Lymphoma | Transformed Indolent Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

United States
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

Flunotinib Maleate Phase II Intermediate-High Risk Bone Fiber Clinical Trial

MF,PMF,PPV-MF,PET-MF

China
SpinChip Diagnostics ASA
University Hospital, Akershus; Scandinavian Contract Research Organization

Recruiting

SpinChip Hs-cTnI Sample Type Validation (HEAT-2)

Acute Myocardial Infarction

Norway
Fudan University

Recruiting

Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)

Rectal Cancer

China
Qilu Hospital of Shandong University

Recruiting

Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection

Carcinoma, Hepatocellular

China
Guangdong Provincial People's Hospital

Not yet recruiting

The Effect of Preserving Inferior Pulmonary Ligamen on Symptom Burden in Thoracoscopic Pneumonectomy (PRO-IPL)

Patient Reported Outcome Measures | Pulmonary Surgical Procedures

China
University Health Network, Toronto

Not yet recruiting

A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment (ABLATE)

Locally Advanced Pancreatic Adenocarcinoma
Zumutor Biologics Inc.

Recruiting

Phase 1 Trial of ZM008 as Single Agent and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Colorectal Cancer | Esophageal Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Pancreas Adenocarcinoma | Diffuse Large B Cell Lymphoma | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Biliary Tract Cancer | High Grade Ovarian Serous Adenocarcinoma

United States
Istanbul Medipol University Hospital

Not yet recruiting

Effectiveness of High Intensity Electromagnetic Therapy and Pelvic Floor Exercises in Women With Urinary Incontinence

Urinary Incontinence
The University of Texas Health Science Center,...

Not yet recruiting

Effects of High Intensity Stepping Training on Gait in Patients With Ataxia

Cerebellar Ataxia

United States
Salvia BioElectronics

Not yet recruiting

Randomized, Double-blind, Sham-controlled Trial to Investigate Combined Occipital and Supra-orbital Neuromodulation in Resistant Migraine. (RECLAIM)

Chronic Migraine | High Frequency Episodic Migraine

Belgium
Maria Sklodowska-Curie National Research Institute...

Not yet recruiting

177Lu-PSMA as a Systemic Adjuvant Treatment in Patients With High and Very High Risk Prostate Cancer (PSMA-ADJUVO)

Prostate Cancer
Dana-Farber Cancer Institute

Not yet recruiting

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study

Cancer Predisposition Syndrome | Predisposition, Genetic

United States
The Swedish School of Sport and Health Sciences
Karolinska Institutet; Sahlgrenska University Hospital, Sweden; Prostate Cancer... and other collaborators

Recruiting

Training for Men Undergoing Androgen Deprivation Therapy. (ADT-train)

Prostate Cancer

Sweden

Search clinical trials for: High comorbidity burden

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