Search clinical trials for: Irinotecan

Total 1526 results

Rutgers, The State University of New Jersey

Recruiting

Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer

Cancer of Rectum

United States
Instituto do Cancer do Estado de São Paulo

Recruiting

Impact of FOLFIRINOX Chemotherapy in IV Stage Colorectal Cancer Patients Previously Exposed to Irinotecan, Fluoropyrimidine and Oxaliplatin (Re-Play)

Colorectal Cancer Stage IV

Brazil
Zhejiang Cancer Hospital

Not yet recruiting

Phase II Clinical Study of Camrelizumab Combined With Chemotherapy or Anlotinib in Advanced Esophageal Squamous Cell Cancer

Stage IV Esophagus Squamous Cell Carcinoma

China
Fujian Cancer Hospital

Recruiting

Phase I/II Study of the Combination of Irinotecan and POF (POFI) and Tislelizumab

Gastric Cancer Stage IV

China
Merck Sharp & Dohme LLC

Recruiting

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

Esophageal Squamous Cell Carcinoma

Japan, Korea, Republic of, Taiwan, China, Italy, Switzerland, Brazil, Germany, Singapore, Turkey, Thailand, Chile, Norway
John Neoptolemos
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest; Deutsches... and other collaborators

Not yet recruiting

Adjuvant Trial in Patients With Resected PDAC Randomized to Allocation of Oxaliplatin- or Gemcitabine-based Chemotherapy by Standard Clinical Criteria or by a Transcriptomic Treatment Specific Stratification Signature

Pancreatic Ductal Adenocarcinoma

Sweden, Germany
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
National Cancer Institute (NCI)

Recruiting

Olaparib in Subjects With Advanced Pancreatic Acinar Cell Carcinoma

Pancreatic Acinar Cell Carcinoma

United States
University Hospital, Ghent
University Ghent; Kom Op Tegen Kanker

Recruiting

Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer (PIPAC-NAL-IRI)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Small Bowel Cancer | Bile Duct Cancer | Peritoneal Carcinomatosis | Peritoneal Metastases | Appendix Cancer

Belgium
Shanghai Zhongshan Hospital

Recruiting

Tislelizumab Plus Cetuximab and Irinotecan vs Third-line Standard-of-care in Refractory mCRC

Colorectal Neoplasms Malignant

China
Merck Sharp & Dohme LLC

Recruiting

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Colorectal Neoplasms

China
Akeso

Recruiting

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Advanced Malignant Tumors

China
Fudan University

Recruiting

Irinotecan Plus Anlotinib or Further in Combination With Penpulimab for Second-line Treatment of mCRC

Metastatic Colorectal Cancer

China
SOLTI Breast Cancer Research Group
Novartis; Alliance Foundation Trials, LLC.

Recruiting

Ribociclib vs. Palbociclib in Patients With Advanced Breast Cancer Within the HER2-Enriched Intrinsic Subtype (HARMONIA)

Metastatic Breast Cancer

United States, Spain, Portugal
Ruijin Hospital

Recruiting

Irinotecan And Bevacizumab Combined With Re-radiotherapy in Recurrent Glioblastoma

Recurrent Glioblastoma

China
Fudan University

Recruiting

Neoadjuvant FOLFOXIRI Versus CapeOX Chemotherapy for Local Advanced Rectal Cancer (RCNAC)

Rectal Cancer

China
Centre Georges Francois Leclerc

Recruiting

Evaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine (TASKIN)

Metastatic Colorectal Cancer

France
First Affiliated Hospital of Wenzhou Medical University

Recruiting

mFOLFOXIRI Compared to mFOLFOX6 or CapeOx as Adjuvant Chemotherapy for Stage IIIB or IIIC Colorectal Cancer

Colorectal Cancer

China
NRG Oncology
National Cancer Institute (NCI); Natera, Inc.

Recruiting

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)

Stage III Colon Cancer

United States, Canada
Second Affiliated Hospital, School of Medicine,...

Recruiting

SALIRI Based Regimen as First-line Treatment for Advanced Metastatic Colorectal Cancer

Advanced Metastatic Colorectal Cancer

China
Zhejiang Cancer Hospital

Recruiting

Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer

Colorectal Cancer Metastatic | Microsatellite Stable | Mismatch Repair-proficient

China
JenKem Technology Co., Ltd.
Peking University Cancer Hospital & Institute

Recruiting

Safety, Tolerability and Preliminary Efficacy of JK1201I in Patients With SCLC

Small Cell Lung Cancer (SCLC)

China
PharmaMar

Recruiting

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Relapsed Small Cell Lung Cancer

United States, Spain, Japan, Korea, Republic of, United Kingdom, Israel, France, Taiwan, Germany, Australia, Belgium, Georgia, Italy, Switzerland, Denmark, Hungary, Poland, Romania, Canada, Brazil, Bulgaria, Austria, Chile, Turkey
Zhejiang Cancer Hospital

Recruiting

UGT1A1-Based Irinotecan Therapy for Locally Advanced Rectal Cancer

Rectal Cancer Stage III

China
Anup Kasi
Cend Therapeutics Inc.

Recruiting

CEND-1 in Combination With Neoadjuvant FOLFIRINOX With or Without Panitumumab (CENDIFOX)

Colon Cancer | Pancreas Cancer | Digestive Cancer

United States
Hospital Israelita Albert Einstein
Ministry of Health, Brazil

Recruiting

Brazilian Total Neoadjuvant Therapy Trial (BRAZIL-TNT)

Colorectal Neoplasms

Brazil
Zhejiang Cancer Hospital

Recruiting

Dendrobium Huoshanense Suppository in Rectal Cancer

Locally Advanced Rectal Cancer

China
M.D. Anderson Cancer Center

Recruiting

ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases

Liver Metastases

United States
Gruppo Oncologico del Nord-Ovest
Seagen Inc.; Servier; Foundation Medicine

Recruiting

Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients (ERASE-CRC)

Stage II Colon Cancer | Stage III Colon Cancer | HER2-positive Colon Cancer | RAS Wild-type Colon Cancer

Italy
Washington University School of Medicine

Recruiting

Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)

Small Cell Lung Carcinoma | Small-cell Lung Cancer

United States
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Study of Irinotecan Liposome Injection-containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma

Pancreatic Cancer Metastatic | Pancreatic Cancer Non-resectable
Tianjin Medical University Cancer Institute and...

Recruiting

PD-1 Inhibitor Combined With Bevacizumab and FOLFIRI Regimen in the Second-line Treatment of Advanced Colorectal Cancer

MSI-H Advanced Colorectal Cancer

China
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Recruiting

Temozolomide and Irinotecan in Patients With MGMT Silenced Colorectal Cancer After Adjuvant Chemotherapy (ERASE-TMZ)

Colorectal Cancer

Italy
Sun Yat-sen University

Recruiting

Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma

Neuroblastoma

China
Haibo Zhang

Recruiting

Tislelizumab Combined With Anlotinib and 2-cycles Irinotecan as Second Line Treatment of SCLC

Small Cell Lung Cancer (SCLC)

China
Sichuan Baili Pharmaceutical Co., Ltd.

Recruiting

SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma.

Esophageal Squamous Cell Carcinomas

China
West China Hospital

Recruiting

FOLFOXIRI for Neoadjuvant Treatment of High-risk Locally Advanced Colorectal Cancer

Neoadjuvant Chemotherapy | High-risk Locally Advanced Colorectal Cancer | FOLFOXIRI Regimen

China
Hutchison Medipharma Limited

Recruiting

A Phase 3 Study to Evaluate Surufatinib Plus Toripalimab in the Treatment of Advanced Neuroendocrine Carcinoma

Advanced Neuroendocrine Carcinoma

China
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Gallbladder Carcinoma | Advanced Biliary Tract Cancer | Extrahepatic Cholangiocarcinoma

China
Dominik Paul Modest
German Research Foundation; Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418)

Colorectal Cancer

Germany
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor Cancer

Metastatic Solid Tumor | Advanced Cancer

United States
Peking University

Recruiting

Toripalimab Plus Bevacizumab and Chemotherapy as Neoadjuvant Therapy in Advanced MSI-H or dMMR Colorectal Cancer

Colorectal Carcinoma

China
Shanghai Pulmonary Hospital, Shanghai, China
Chinese Academy of Sciences

Not yet recruiting

Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Small Cell Lung Cancer

China
National Cancer Center, Korea
Seoul National University Bundang Hospital

Recruiting

Survival Rate and Treatment Cost in Patients With Pancreatic Cancer With the Advent of New Chemotherapeutic Agents in Korea: An Analysis Using NHIS Database and K-PaC Registry Focusing on the Newest One, Liposomal Irinotecan

Pancreatic Cancer

Korea, Republic of
Nanfang Hospital of Southern Medical University

Recruiting

A Phase II Study of Carelizumab Combined With Irinotecan and Apatinib of Second-line Treatment for Advanced Gastric Cancer

Gastric Cancer

China
Jiangsu Cancer Institute & Hospital

Recruiting

Surufatinib Combine With Immunotherapy and Chemotherapy for Second-line Treatment in Advanced Colorectal Cancer

Advanced Colorectal Cancer

China
Erasmus Medical Center
Dutch Cancer Society; Dutch Pancreatic Cancer Group

Recruiting

Perioperative or Adjuvant mFOLFIRINOX for Resectable Pancreatic Cancer (PREOPANC-3)

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Resectable Pancreatic Adenocarcinoma

Netherlands, Sweden, Norway
Guangzhou University of Traditional Chinese Medicine
University of Houston

Recruiting

XCHT for Irinotecan-Induced Gut Toxicities (Run-in Study)

Diarrhea | Malignant Tumor

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Study of TQB3616 Capsules Combined With Anlotinib Hydrochloride Capsules or Standard Chemotherapy Second-line and Above in the Treatment of Advanced Lung Cancer

Advanced Lung Carcinoma

China
University of California, Irvine
Natera, Inc.; Taiho Pharmaceutical Co., Ltd.

Recruiting

Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas

Colorectal Cancer | Colon Adenocarcinoma

United States

Search clinical trials for: Irinotecan

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