Search clinical trials for: Randomized double blind placebo controlled clinical trial

Total 130328 results

Viridian Therapeutics, Inc.

Recruiting

A Randomized, Double-masked, Placebo-controlled Safety, Tolerability, and Efficacy Study of VRDN-001, a Humanized Monoclonal Antibody Directed Against the IGF-1 Receptor, in Participants With Chronic Thyroid Eye Disease (TED)

Thyroid Eye Disease

United States, Turkey
Relmada Therapeutics, Inc.

Recruiting

Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as Adjunctive Treatment for MDD (RELIGHT)

Depression | Major Depressive Disorder

United States
Military Institute od Medicine National Research...
ABM Industries

Recruiting

Randomized, Double-blind, Placebo-controlled Trial of the Efficacy and Safety of Tianeptine in the Treatment of Covid Fog Symptoms in Patients After COVID-19. (COVMENT)

Nervous System Diseases

Poland
Devintec Sagl
Meditrial SrL

Recruiting

Devintec OR-AT0222 Oral Gel for the Treatment of Canker Sores: A Double Blind, Randomized, Placebo Controlled Clinical Investigation

Recurrent Aphthous Ulcer

Italy
The Florey Institute of Neuroscience and Mental...
The University of Queensland; Mobius Medical Pty Ltd.

Recruiting

A Double-blind Randomised, Placebo-controlled Clinical Trial to Test Ambroxol Treatment in ALS (AMBALS)

Amyotrophic Lateral Sclerosis

Australia
Shionogi

Recruiting

A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke (REvive)

Acute Ischemic Stroke

Japan, Israel, United States, Australia, Hong Kong
Centre Hospitalier Universitaire de Nice

Recruiting

Contribution of an Antiviral Drug (Valaciclovir) in the Treatment of Generalized Periodontitis (Stage III or IV and Grade A, B or C): Prospective, Randomized and Double Blind Clinical Trial (HERPARO)

Periodontitis Chronic Generalized Severe

France
Sun Yat-sen University
JIANGSU JIBEIER PHARMACEUTICAL CO.,LTD

Not yet recruiting

A Multi-center, Randomized, Double-blind, Phase III Clinical Trial of Leucogen Versus Placebo on Leukocyte and Platelet Whole-course Management Assisted by PFLL Chemotherapy in the Treatment of Stage IV, Recurrent or Metastatic NPC

Nasopharyngeal Carcinoma | Chemotherapy | Myelosuppression | Leucogen

China
Assiut University

Not yet recruiting

Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine

Inguinal Hernia
Xeolas Pharmaceuticals Limited

Recruiting

A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Alendronic Acid on Alveolar Bone Remodeling After Tooth Extraction (XEOLAS)

Bone Loss, Alveolar

Spain
University Hospital, Tours

Recruiting

Evaluation of Efficacy and Safety of Rituximab in Patients With Progressive Interstitial Lung Disease (ILD) With Inflammatory Component: a Multicentre Double-blind Placebo-controlled Randomized Trial (EvER-ILD2)

Lung Diseases

France
Beijing Tiantan Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy of Pentoxifylline on Cerebrovascular Function in Patients With Cerebral Small Vessel Disease(PERFORM) (PERFORM)

Cerebral Small Vessel Diseases

China
Parnassia Addiction Research Centre
Radboud University Medical Center; Columbia University; Academisch Medisch Centrum... and other collaborators

Not yet recruiting

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Cocaine Use Disorder
Sichuan Cancer Hospital and Research Institute

Recruiting

Nituzumab (Taixinsheng ®） A Prospective, Randomized, Double-blind, Placebo-controlled, Multicenter Phase II Clinical Study on the Efficacy and Safety of Combined Induction Chemotherapy for Locally Advanced Nasopharyngeal Carcinomatreatment of Locally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
LUCINDA BATEMAN, MD
Endourage, LLC

Not yet recruiting

Double-Blind Randomized Placebo-Controlled Trial of a Proprietary Full Hemp Flower Formulation for Long COVID

Post-acute COVID-19 Syndrome

United States
Hospital General de Agudos Bernardino Rivadavia
Hospital Italiano de Buenos Aires

Recruiting

Efficacy of Individualized Homeopathic Remedies on Migraine: a Randomized, Triple-blind, Placebo Controlled Study. (HOMEOMIG)

Migraine

Argentina
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Beijing Tiantan Hospital
GrandPharma (China) Co., Ltd.

Recruiting

Study on Tirofiban With Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY)

Branch Atheromatous Disease

China
Marinus Pharmaceuticals

Not yet recruiting

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

CDKL5 Deficiency Disorder
Mayo Clinic

Recruiting

Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy

Multiple System Atrophy

United States
Shiraz University of Medical Sciences

Not yet recruiting

Saffron and Ulcerative Colitis

Ulcerative Colitis
Drug Induced Liver Disease Study Group
Beijing Union Pharmaceutical Factory

Recruiting

The Multi-Center, Randomized, Double-blind, Positive Controlled Clinical Trial of Bicyclol in the Treatment of Acute DILI

Drug-Induced Acute Liver Injury

China
Istituto Ortopedico Rizzoli

Recruiting

Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis

Knee Osteoarthritis

Italy
Rennes University Hospital

Recruiting

Evaluation of the Efficacy and Safety of Autologous Fat Injection Into the Intersphincter Space in Fecal Incontinence: a Randomized, Placebo-controlled, Cross-over, Double-blind Trial (AUTOGRAFI)

Fecal Incontinence

France
Kwang Dong Pharmaceutical co., ltd.

Recruiting

A Phase 3, Bridging, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of Subcutaneously Administered Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder (With or Without Decreased Arousal)

Hypoactive Sexual Desire Disorder

Korea, Republic of
Laval University
Canadian Institutes of Health Research (CIHR); Resverlogix Corp

Not yet recruiting

Apabetalone for Pulmonary Arterial Hypertension (APPROACH-2)

Pulmonary Arterial Hypertension

Canada
AstraZeneca

Recruiting

D9319C00001- 1L OC Mono Global RCT (MONO-OLA1)

Ovarian Cancer

China, Vietnam, Russian Federation, Ukraine, South Africa, Turkey, India, Peru, Colombia, Poland, Chile, Philippines
ProQR Therapeutics

Recruiting

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. (BRIGHTEN)

Eye Diseases | Neurologic Manifestations | Retinal Degeneration | Retinal Dystrophies | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

Belgium, Brazil, Canada, Germany, Italy, Netherlands, United Kingdom
Federal University of Paraíba

Recruiting

Effects of Dualsite Anodic tDCS on Lower Limbs Function in Patients After Stroke: Randomized, Double-blind, Placebo-controlled, Crossover Trial

Stroke, Chronic

Brazil
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Korea, Republic of, United States, Spain, France, Belgium, China, Taiwan, United Kingdom, Australia, Czechia, Hungary, Poland, Russian Federation
RenJi Hospital

Recruiting

A Prospective, Randomized, Double-blinded, Multi-center Clinical Trial to Evaluate the Efficiency and Safety of Anti-PD1 Antibody (Camrelizumab) Combined With Paclitaxel(Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer Metastatic | Pancreatic Cancer Stage IV

China
Sahlgrenska University Hospital, Sweden
The Swedish Research Council; Sjöbergstiftelsen; VGregion

Recruiting

Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial (FIDURA)

Gynecologic Cancer | Malignant Neoplasm | Malignant Neoplasm of Large Intestine | Malignant Neoplasm of Colon | Malignant Neoplasm of Prostate | Malignant Neoplasm of Rectum | Malignant Neoplasm of Anus | Malignant Neoplasm of Urinary Bladder | Malignant Neoplasm of Cervix | Malignant Neoplasm of Ovary

Sweden
University Hospital, Rouen

Not yet recruiting

Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis (PREMS)

Recurrent Aphtous Stomatitis
Dongzhimen Hospital, Beijing
The Second Hospital of Hebei Medical University; Peking University Third Hospital and other collaborators

Recruiting

Xingnaojing for Mild-to-severe Acute Ischemic Stroke (XMAS-2)

Stroke, Ischemic | Stroke, Acute | Acute Ischemic Stroke

China
Mauro Manconi
Clinical Trial Unit Ente Ospedaliero Cantonale

Recruiting

A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo (Glu-REST)

Restless Legs Syndrome

Switzerland, Italy
Masonic Cancer Center, University of Minnesota

Recruiting

RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

Lung Cancer | Adenocarcinoma of Lung

United States
Philippe Bégin
The Hospital for Sick Children; Centre de recherche du Centre hospitalier universitaire... and other collaborators

Recruiting

Omalizumab to Accelerate a Symptom-driven Multi-food OIT (BOOM)

Immunotherapy | Physiological Effects of Drugs | Food IgE-mediated Allergy | Omalizumab

Canada
Centre Hospitalier Universitaire Dijon

Recruiting

Benefit of a Flash Dose of Corticosteroids in Digestive Surgical Oncology: a Randomized, Double Blind, Placebo-controlled Trial (CORTIFRENCH)

Elective Surgery for Any Digestive Cancer

France
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR)

Recruiting

Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT) (LiFT)

Fractures

Canada
Göteborg University
Sahlgrenska University Hospital, Sweden

Recruiting

Swedish Iodine in Pregnancy and Development in Children (SWIDDICH) Study (SWIDDICH)

Pregnancy | Cognitive Developmental Delay | Thyroid Gland; Node

Sweden
AgoneX Biopharmaceuticals, Inc.

Not yet recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of Subcutaneous AGX-201 for Migraine Prophylaxis

Migraine Prophylaxis
Amgen

Completed

Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100

Drug Toxicity

United States
Pfizer

Terminated

PLACEBO-CONTROLLED SAFETY STUDY OF RITLECITINIB (PF-06651600) IN ADULTS WITH ALOPECIA AREATA (Allegro2a)

Alopecia Areata

United States, Australia, Canada, Poland
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Phase 2 Shigella Vaccine and Challenge

Immunisation | Shigella Infection

United States
Inhibikase Therapeutics, Inc.

Active, not recruiting

A Randomized, Double-Blind, Placebo-Controlled Trial of IkT-148009 in Untreated Parkinson's Disease

Parkinson Disease

United States
Perception Neuroscience
Precision For Medicine; IQVIA Biotech

Completed

A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD

Treatment Resistant Depression

United States, Germany, Poland
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

Completed

Randomized, Double-Blind Clinical Trial for Parkinson's Disease (Early and Moderate) (PD)

Parkinson Disease

United States
Amylyx Pharmaceuticals Inc.
ALS Association; ALS Finding a Cure; Northeast ALS Consortium; Neurological Clinical... and other collaborators

Completed

AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) (CENTAUR)

Central Nervous System Diseases | Nervous System Diseases | Neuromuscular Diseases | Neurodegenerative Diseases | Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Spinal Cord Diseases | TDP-43 Proteinopathies

United States
China Medical University Hospital

Completed

The Safety and Efficacy Evaluation of XSLJZ in Advanced Hepatocellular Carcinoma Patients With Multiple Protein Kinase Inhibitor Therapy: A Randomized, Double-Blind, Controlled Trial

Hepatocellular Carcinoma

Taiwan

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