Search clinical trials for: Rare Diseases

Total 374004 results

Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD)

Neuromyelitis Optica Spectrum Disorders

China
Spinogenix
Avance Clinical Pty Ltd.

Not yet recruiting

Study of SPG601 in Adult Men With Fragile X Syndrome

Fragile X Syndrome

United States
Radboud University Medical Center
London School of Hygiene and Tropical Medicine; Malaria Research and Training...

Not yet recruiting

Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali

Malaria,Falciparum
Case Comprehensive Cancer Center

Not yet recruiting

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

Pancreatic Adenocarcinoma | Ovarian Cancer | Epithelial Ovarian Cancer

United States
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of Patients With Systemic Sclerosis Without Specific or Associated Autoantibodies (SCLERONAB)

Systemic Sclerosis

France
Chiang Mai University

Recruiting

Study Compares Pneumothorax Recurrence: Absorbable Mesh vs. Pleurectomy in Primary Spontaneous Pneumothorax.

Primary Spontaneous Pneumothorax

Thailand
Cytokinetics

Not yet recruiting

A Study to Evaluate the Effect of Aficamten in Pediatric Patients (Age 12 to <18 Years) With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM). (CEDAR-HCM)

Pediatric | Symptomatic Obstructive Hypertrophic Cardiomyopathy
Children's Hospital Los Angeles

Not yet recruiting

Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot Study

Cystic Fibrosis | Constipation Chronic Idiopathic

United States
Sun Yat-sen University

Not yet recruiting

A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment

Primary Mediastinal Large B Cell Lymphoma
Liu Huang
Beijing GeneX MedLab Co., Ltd

Recruiting

Exploratory Study of Precise Therapy for Advanced Tumor Patients With Malignant Hydrothorax or Ascites by Using PTC Drug Sensitivity Testing

Breast Cancer | Gastric Cancer | Colorectal Cancer | Lung Cancer

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Assessment of the Alignment of the Atlas and Surrounding Tissues in Chronic Whiplash Associated Disorder (MRAtlas)

Chronic Whiplash Associated Disorder

Netherlands
IRCCS Ospedale San Raffaele

Not yet recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Rare Diseases | Corneal Neovascularization | Limbal Stem Cell Deficiency | Aniridia | Neurotrophic Keratopathy | Ocular Cicatricial Pemphigoid | Ocular Graft-versus-host Disease | EEC Syndrome
Changhai Hospital
West China Hospital; Shandong Provincial Hospital; The First Affiliated Hospital... and other collaborators

Not yet recruiting

Multimodal Endoscopic Image Fusion for Assessing Infiltration in Superficial Esophageal Squamous Cell Carcinoma

Esophageal Neoplasms Malignant

China
Beijing Immunochina Medical Science & Technology...
Guangdong Provincial People's Hospital

Not yet recruiting

IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer

HER2 Expression / Amplification in Patients With Biliary Tract Cancer

China
University of Miami
GlaxoSmithKline

Not yet recruiting

Study Evaluating Safety, Tolerability, and Metabolism of Niraparib

Ovarian Cancer

United States
Başakşehir Çam & Sakura City Hospital

Not yet recruiting

Evaluation of the Effectiveness of Genicular Block in Postoperative Analgesia in Patients Undergoing Knee Arthroscopy

Knee Pain Chronic
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis (BioMol-MA)

Non-Tuberculous Mycobacterial Pneumonia | Cystic Fibrosis Lung

Italy
Wake Forest University Health Sciences

Not yet recruiting

Pedal Movement - Implementing Cycling as a Mobility Option

Ileus

United States
Axsome Therapeutics, Inc.

Recruiting

SUNOSI® (Solriamfetol) Pregnancy Registry

Obstructive Sleep Apnea | Narcolepsy | Pregnant Women and Their Offspring

United States
Serum Institute of India Pvt. Ltd.

Not yet recruiting

Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV

Hepatitis B Immunization | Diptheria Immunization | Tetanus Immunization | Pertussis Immunization | Haemophilus Influenzae Type B Immunization | Polio Immunization
Diakonhjemmet Hospital

Recruiting

Evaluation of Cognitive Behavioral Therapy for Long-term Pain in Rheumatic Disease, Including Validation of AE-FS

Rheumatic Diseases | Pain, Chronic

Norway
Brugmann University Hospital

Recruiting

Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone

Kidney Stone

Belgium
Tarsus University

Not yet recruiting

Effect of Placenta Delivery Method on Pain, Bleeding and Comfort

Placenta Abruptio

Turkey
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

JAVEMACS: Japan AVElumab Maintenance And Continuous Treatment Study

Urothelial Carcinoma

Japan
Ain Shams University

Recruiting

Homocysteine in Critically Ill Preeclampsia

Critical Illness | Pre-Eclampsia

Egypt
Peking Union Medical College Hospital

Recruiting

68Ga-NOTA-RM26 PET/CT in Glioma Patients

Glioma

China
Keymed Biosciences Co.Ltd

Not yet recruiting

Single Dose Escalation Study of CM383 in Healthy Volunteers

Alzheimer Disease
Taipei Medical University
Taipei Medical University WanFang Hospital

Not yet recruiting

The Effects of Different Vibration Exercises on COPD Patients

COPD | Vibration Therapy | COPD Chronic Obstructive Pulmonary Disease

Taiwan
Zhejiang Cancer Hospital

Not yet recruiting

Sintilimab After Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma

Esophageal Cancer | Elderly Patients | Immunotherapy | Sintilimab | Chemoradiotherapy
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Acquired Pure Red Cell Aplasia | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Acquired Amegakaryocytic Thrombocytopenia
Ainsworth Institute of Pain Management
Saluda Medical Pty Ltd

Recruiting

Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for Treatment of Chronic Pelvic Pain: HOPE Trial

Pudendal Neuralgia | Chronic Pelvic Pain

United States
Massachusetts General Hospital

Recruiting

The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)

Recurrent Respiratory Papillomatosis | Pulmonary Neoplasm

United States
Charite University, Berlin, Germany
Almond Board of California

Not yet recruiting

Effects of Almonds in Glucose-intolerant Adults (AGAMEMNON) (AGAMEMNON)

PreDiabetes | NAFLD

Germany
Charles University, Czech Republic

Not yet recruiting

Efficiency and Safety of the Prolonged Use of Heat and Moisture Exchangers in ICU (FILTRex)

VAP - Ventilator Associated Pneumonia
University of Washington
National Institute on Aging (NIA)

Not yet recruiting

A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors (SLEEP-COG)

Delirium | Critical Illness | Cognitive Impairment | Dementia | Sleep Disturbance | Cognitive Decline | Alzheimer's Disease | Circadian Dysrhythmia
VA Office of Research and Development

Not yet recruiting

Home-based Conservative Care Model for Advanced Kidney Disease

Chronic Kidney Diseases

United States
University Hospital Tuebingen
German Center for Mental Health

Not yet recruiting

Pharmacologic Treatment Augmentation in Chronic Depression (Ket+CBASP)

Major Depressive Disorder

Germany
Northwestern University
National Cancer Institute (NCI); BrainUp Inc

Not yet recruiting

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recurrent WHO Grade 2 Glioma | Recurrent Glioblastoma, IDH-Wildtype | Recurrent WHO Grade 3 Glioma | Recurrent WHO Grade 4 Glioma

United States
Swedish Medical Center

Recruiting

Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial

Primary Spontaneous Pneumothorax

United States
University of Western Sydney
University of Auckland, New Zealand

Recruiting

Body Surface Gastric Mapping vs Gastric Emptying Scintigraphy on Clinical Management in Gastroparesis

Gastroparesis

Australia
Centre hospitalier de l'Université de Montréal...

Not yet recruiting

UltraSound Evaluation of Fluid tOleRanCE for Acute Kidney Injury (USE-the-FORCE)

Acute Kidney Injury

Canada
University of Rochester
National Institutes of Health (NIH)

Not yet recruiting

Outcomes of a Palliative Care Intervention to Improve Kidney Therapy Decision-Making for Older People With Advanced Chronic Kidney Disease (CKD) (CKD-EDU)

Chronic Kidney Diseases

United States
Peking Union Medical College Hospital
Shengjing Hospital; The Affiliated Hospital of Qingdao University; Children's... and other collaborators

Recruiting

Belimumab After Rituximab in Resistant Primary Juvenile SS (BRRPJS)

Pediatric ALL | Sjogren's Syndrome

China
Neuraly, Inc.

Not yet recruiting

A Study to Evaluate DD01 in Overweight/Obese Subjects With MASLD/MASH

NAFLD | NASH

United States
Mario Negri Institute for Pharmacological Research

Not yet recruiting

Blood Flow Conditions and Sounds in AVFs (APOLLO)

End Stage Renal Disease

Italy
University of Southern California
University of California, Irvine

Not yet recruiting

Heartrate and Breathing Effects on Attention and Memory

Alzheimer Disease | Age-related Cognitive Decline
Novartis Pharmaceuticals

Not yet recruiting

Home Reported Outcomes in PNH

Paroxysmal Nocturnal Hemoglobinuria
Jaseng Medical Foundation

Recruiting

Integrative Korean Medicine Treatment for Pediatrics After Traffic Accident: Retrospective Chart Review Study and Survey

Pediatric ALL | Traffic Accident

Korea, Republic of
SamA Pharmaceutical Co., Ltd

Recruiting

The Efficacy and Safety of Atock Dry Syrup With Acute Bronchitis Patients

Acute Bronchitis

Korea, Republic of

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