Search clinical trials for: digoxin

Total 210 results

Hospital Ana Nery

Unknown

Intensive Versus Conventional Digoxin Use in Patients With Heart Failure (ICHF)

Heart Failure

Brazil
The Alfred

Completed

Digoxin Withdrawal in Stable Heart Failure

Heart Failure

Australia
Boehringer Ingelheim

Completed

Interaction of BI 425809 With Midazolam, Warfarin, Omeprazole and Digoxin

Healthy

Germany
Takeda

Completed

Drug-Drug Interaction Study Between TAK-272 and Itraconazole, Digoxin or Midazolam

Japanese Healthy Adult Males

Japan
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)

Heart Diseases | Cardiovascular Diseases | Atrial Fibrillation | Arrhythmia
Bristol-Myers Squibb

Completed

Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients

Rheumatoid Arthritis
Eisai Inc.

Completed

A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Rifampin, Digoxin, or Donepezil

Healthy Subjects

United States
Hoffmann-La Roche

Completed

A Pharmacokinetics Study to Investigate the Effect of Vemurafenib on Digoxin in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma

Malignant Melanoma, Neoplasms

Russian Federation, Korea, Republic of, Israel, South Africa, Belarus
Karolinska Institutet

Completed

Kinetics of Fluvoxamine and Digoxin in Subjects With Different MDR1 Genotypes

Depression

Sweden
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Effect of a Single Dose of Digoxin on the Actions in the Bodies of Healthy Subjects After Having Taken Several Doses of YM178

Healthy

France
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Digoxin

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Digoxin

United States
Tesaro, Inc.

Completed

An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects

Chemotherapy-induced Nausea and Vomiting

United States
Bristol-Myers Squibb
Pfizer

Completed

Phase 1 Drug Interaction Study of the Effect of Apixaban on the PK of Digoxin in Healthy Subjects

N/A - Healthy Subjects
Lexicon Pharmaceuticals

Completed

DDI Study With Multiple-dose LX4211 and Single Dose Digoxin

Healthy

United States
Cairo University

Completed

A Prospective Study of Different Digoxin Treatment Regimens in Egyptian Hospital

Atrial Fibrillation
Genzyme, a Sanofi Company

Completed

A Phase 1 Study Evaluating Eliglustat's Effects on Pharmacokinetics, Safety & Tolerability of Digoxin in Healthy Adults

Healthy Volunteer

United States
Hospital Clinic of Barcelona
Hospital Universitario Ramon y Cajal; Puerta de Hierro University Hospital; Fundación... and other collaborators

Completed

Spanish Atrial Fibrillation And Resynchronization Study (SPAREIII)

Atrial Fibrillation | Chronic Heart Failure | Cardiomyopathy, Dilated

Spain
Boehringer Ingelheim

Withdrawn

Effect of BI 1181181 on Midazolam, Warfarin, Omeprazole and Digoxin

Healthy

Germany
Bial - Portela C S.A.

Completed

The Effect of BIA 2-093 on the Steady-state Pharmacokinetics of Digoxin

Epilepsy

Portugal
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study in Health Adult Volunteers

Healthy

United States
Debiopharm International SA

Withdrawn

Phase I Interaction Study of Istaroxime and Digoxin in Subjects With Stable Heart Failure

Heart Failure
Eli Lilly and Company

Completed

A Study of the Effect of Dulaglutide on How Body Handles Digoxin in Healthy Participants

Diabetes Mellitus, Type 2

United States
Boehringer Ingelheim

Completed

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Healthy
BTG International Inc.
GlaxoSmithKline

Completed

Efficacy Study of Digibind for Treatment of Severe Preeclampsia

Pre-eclampsia

United States
Boehringer Ingelheim

Completed

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Healthy
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Boehringer Ingelheim

Completed

Pharmacokinetics, Safety and Tolerability of Digoxin With or Without Co-administration of BI 1356 in Healthy Volunteers

Healthy
Boehringer Ingelheim

Completed

Relative Bioavailability of Dabigatran and Digoxin in Healthy Male and Female Volunteers

Healthy
Bristol-Myers Squibb

Completed

Study to Determine the Potential DDIs When the Daclatasvir/Asunaprevir/BMS-791325 Three Drug Antiviral Combination Tablet (FDC) is Coadministered With a Cocktail of Cytochrome P450 (CYP) Probe Substrates and Transporter Probe Substrates (Digoxin and Pravastatin) in Healthy Subjects

Hepatitis C
Boehringer Ingelheim

Completed

Drug Interaction Study of Digoxin and BI 10773

Healthy

Germany
Seoul National University Hospital

Completed

Clinical Trial to Evaluate the Influence of Genotype and DDIs of Aspirin on the PK/PD of Clopidogrel and PK of Digoxin

DRUG REACTIONS

Korea, Republic of
University of Illinois at Chicago
American College of Clinical Pharmacy

Completed

Digoxin Dosing in Heart Failure: A Simplified Nomogram Versus Standard Care

Heart Failure

United States
Kocaeli University

Unknown

Digoxin Versus Ivabradine in Heart Failure With Reduced Ejection Fraction (DIVA-REF)

Heart Failure

Turkey
Cocco, Giuseppe, M.D.
Cardiology Office, Rheinfelden, Switzerland

Completed

Efficacy Study of Digoxin & Ivabradine to Treat Heart Failure (Dig&Iva)

Cardiac Failure

Switzerland
Meir Medical Center

Unknown

Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy

Arrhythmia | Hypotension | ECG Changes

Israel
Atlanta Heart Specialists, LLC
Gilead Sciences

Unknown

Ranolazine, Ethnicity and the Metabolic Syndrome (REMS)

Coronary Artery Disease | Metabolic Syndrome | Angina

United States
Rambam Health Care Campus

Completed

Antibodies to Digoxin for Bipolar Disorder

Bipolar Disorder

Israel
White, Katharine O'Connell, M.D., M.P.H.
Society of Family Planning

Completed

A Trial of Digoxin Before Second-Trimester Abortion

Induced Abortion

United States
Janssen R&D Ireland

Completed

A Study to Investigate the Effect of Steady-State TMC278 on the Pharmacokinetics of a Single Dose of Digoxin

Healthy

Belgium
Tibotec Pharmaceuticals, Ireland

Completed

TMC435-TiDP16-C108 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Digoxin and Between TMC435 and Rosuvastatin

Hepatitis C Virus
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics and Safety of Digoxin in Healthy Volunteers.

Healthy
National Institute on Aging (NIA)
University of Toledo Health Science Campus

Unknown

Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease

Hypertension | Hemodialysis

United States
Puma Biotechnology, Inc.

Completed

Study Evaluating The Potential Effect Of Multiple Doses Of Neratinib On The Pharmacokinetics Of A Single Dose Of Digoxin

Healthy

United States
Astellas Pharma Inc

Completed

A Study to Investigate the Effect of YM150 on the Plasma Concentration of Digoxin in Healthy Subjects

Healthy | Pharmacokinetic of Digoxin

France
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Digoxin and PA21

Drug Interaction Potentiation

United States
Sanofi

Completed

Effect of Addition of Dronedarone to Standard Rate Control Therapy on Ventricular Rate During Persistent Atrial Fibrillation (AFRODITE) (AFRODITE)

Atrial Fibrillation

Netherlands
AstraZeneca

Completed

Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in Healthy Subjects

Rheumatoid Arthritis | Healthy Volunteers

United Kingdom
Sunovion

Completed

Digoxin Drug-Drug Interaction With Lurasidone HCl

Schizophrenia

United States

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