Search clinical trials for: immunosuppressive switch (to Certican)

Total 16126 results

Novartis Pharmaceuticals

Completed

Efficacy and Safety of the Switch From Sirolimus to Everolimus in Stable Maintenance Renal Transplant Patients Receiving a Calcineurin Inhibitor Free Regimen

Renal Transplantation

Switzerland
Novartis Pharmaceuticals

Completed

Feasibility and Safety of Early Switch to Everolimus From Cyclosporine in de Novo Renal Transplant Patients

De Novo Renal Transplantation

Norway
Julia Brown

Completed

SWITCH Clinical Trial for Patients With Rheumatoid Arthritis Who Have Failed an Initial TNF-blocking Drug. (SWITCH)

Rheumatoid Arthritis

United Kingdom
Beijing Sanbo Brain Hospital
Marino Biotechnology Co., Ltd.

Unknown

Pilot Study of Autologous Chimeric Switch Receptor Modified T Cells in Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme

China
Chung Shan Medical University

Unknown

Etanercept Versus Adalimumab in the Treatment of Patients With Ankylosing Spondylitis. A Switch Study

Ankylosing Spondylitis

Taiwan
Veloxis Pharmaceuticals

Completed

Switching Study of Kidney Transplant Patients With Tremor to LCP-Tacro (STRATO) (STRATO)

Renal Failure | Tremors

United States
Bristol-Myers Squibb

Completed

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, United States, Argentina, Brazil, Canada, Mexico, Peru, Korea, Republic of, Sweden, Australia, Russian Federation, Poland, Puerto Rico, Czech Republic, Denmark, South Africa, Switzerland
Bristol-Myers Squibb

Completed

Phase IIIB Switching From Intravenous to Subcutaneous Study

Arthritis, Rheumatoid

United States, Mexico, Canada
Rüdiger B. Müller
Bristol-Myers Squibb

Completed

Introducing a Single IV Abatacept Treatment in RA Patients Currently Receiving Weekly SC Abatacept to Simulate a Holiday (A-BREAK)

Rheumatoid Arthritis

Switzerland
London Health Sciences Centre

Completed

Study of Sirolimus Versus Mycophenolate Liver Transplant Recipients With Recurrent Hepatitis C Virus (HCV)

Hepatitis C

Canada
University Hospital Muenster
Novartis

Unknown

Study to Assess Immune Function and MRI Disease Activity in RRMS Patients When Switching From Natalizumab to Gilenya (ToFingo2)

Relapsing Remitting Multiple Sclerosis

Germany
Northern Italy Leukemia Group

Completed

Intrathecal DepoCyte and Lineage-targeted Minimal Residual Disease-oriented Therapy of Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

Italy
Novartis Pharmaceuticals

Terminated

Disease Control and Safety in Patients With Relapsing Remitting Multiple Sclerosis (RRMS) Switching From Natalizumab to Fingolimod (TOFIINGO)

Relapsing Remitting Multiple Sclerosis (RRMS)

Germany, Spain, Australia, Israel, Switzerland, Italy, Austria, Greece, Hungary, Czech Republic, Finland
Hoffmann-La Roche

Completed

A Study of Tocilizumab and Methotrexate Treatment Strategies (Adding Tocilizumab to Methotrexate Versus Switching to Tocilizumab) in Patients With Active Rheumatoid Arthritis With Inadequate Response to Prior Methotrexate Treatment

Rheumatoid Arthritis

Germany, Norway, Spain, France, Sweden, United States, Estonia, United Kingdom, Greece, Russian Federation, Italy, Denmark, Netherlands, Thailand, Latvia, Croatia, Serbia, Israel, Brazil, Romania
Boehringer Ingelheim

Completed

A Randomised, db, Placebo-controlled Study of BI 1356 for 18 Weeks Followed by a 34 Week Double-blind Extension Period (Placebo Patients Switched to Glimepiride) in Type 2 Diabetic Patients for Whom Treatment With Metformin is Inappropriate

Diabetes Mellitus, Type 2

United States, Canada, Mexico, Philippines, Romania, Russian Federation, Ukraine
Michael Schiff, MD
UCB Pharma

Completed

Can TNF-Alpha Incomplete Secondary Responders Attain a Safe and Efficacious Response Switching to Cimzia

Rheumatoid Arthritis

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Switching Anti-TNF-Alpha Agents in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
Rennes University Hospital
Novartis

Terminated

Switch From Tacrolimus to Cyclosporin in the Treatment of Recurrent Hepatitis C After Liver Transplantation

Chronic Hepatitis C | Evidence of Liver Transplantation

France
Centocor Ortho Biotech Services, L.L.C.

Completed

Open-label, Pilot Protocol of Patients With Rheumatoid Arthritis Who Switch to Infliximab After Incomplete Response to Etanercept

Rheumatoid Arthritis
Hannover Medical School

Unknown

Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant (BKVIRUS)

Virus Diseases | Disorder Related to Renal Transplantation | Immunosuppression Related Infectious Disease

Germany
Erasmus Medical Center
Novartis Pharmaceuticals

Terminated

Myfortic Versus Azathioprine in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

Netherlands
Soonchunhyang University Hospital

Completed

Triamcinolone Paste to Reduce the Incidence of Postoperative Sore Throat

Tracheal Intubation

Korea, Republic of
Hannover Medical School
Hoffmann-La Roche

Completed

Withdrawal of Steroids, Cyclosporine A Dose Reduction and Switch to Mycophenolatmofetile After Heart Transplantation

Heart Transplantation

Germany
OHSU Knight Cancer Institute
Oregon Health and Science University

Terminated

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions

United States
Anhui Provincial Hospital

Not yet recruiting

Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases

Acute Graft Versus Host Disease | Malignant Hematologic Neoplasm

China
Adicet Therapeutics

Not yet recruiting

A Phase 1/2 Trial of ADI-270 in ccRCC

Clear Cell Renal Cell Carcinoma
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Belatacept in Heart Transplantation

Heart Transplant

United States
University of Kansas Medical Center

Not yet recruiting

Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes

Diabetes Mellitus, Type 2 | Osteoarthritis, Knee

United States
Pak Emirates Military Hospital

Not yet recruiting

Comparison of Efficacy of Methotrexate and Azathioprine in Patients With Chronic Actinic Dermatitis: A Randomized Controlled Trial

Chronic Actinic Dermatitis
M.D. Anderson Cancer Center

Not yet recruiting

T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

Metastatic Soft-tissue Sarcoma

United States
Federal Research Institute of Pediatric Hematology...

Recruiting

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Malignant Lymphoma | Biphenotypic Acute Leukemia

Russian Federation
Fudan University

Recruiting

A Phase II Trial of Adebrelimab in Combination With NALIRIFOX in LAPC

Pancreatic Cancer

China
M.D. Anderson Cancer Center

Not yet recruiting

A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute Leukemias

Refractory Acute Leukemia | Relapsed Acute Leukemia

United States
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC

Not yet recruiting

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

Lymphoma | Primary Central Nervous System Lymphoma

United States
AC Camargo Cancer Center

Recruiting

Everolimus 5 mg vs 10 mg/Daily for Patients With Neuroendocrine Tumors (EVENET)

Progression | Neuroendocrine Tumors | Neuroendocrine Tumor of the Lung | Neuroendocrine Tumor Grade 2 | Neuroendocrine Tumor Grade 1 | Neuroendocrine Tumor of Pancreas | Neuroendocrine Tumor Carcinoid

Brazil
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Zanubrutinib and G-CHOP in Untreated Intermediate-high Risk Follicular Lymphoma

FL
The First Affiliated Hospital with Nanjing Medical...
Nanjing Legend Biotech Co.

Not yet recruiting

LCAR-M61S and LCAR-M61D in Treatment of Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.

Primary Membranous Nephropathy

China
Soligenix

Not yet recruiting

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL (FLASH2)

Mycosis Fungoides | Cutaneous T Cell Lymphoma | CTCL | CTCL/ Mycosis Fungoides
The First Affiliated Hospital with Nanjing Medical...
Jiangsu Hengrui Pharmaceuticals Co.,Ltd

Not yet recruiting

To Evaluate the Efficacy of Adebrelimab Combined With Chemotherapy After HIFU Induction Neoadjuvant Therapy HR+/HER2- Breast Cancer

Breast Cancer | HR+/HER2- Breast Cancer
Xianmin Song, MD

Recruiting

Reduced Intensity Conditioning With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory Peripheral T-cell Lymphoma.

Peripheral T Cell Lymphoma

China
David Ilan Sandberg

Not yet recruiting

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

Recurrent Ependymoma | Recurrent Medulloblastoma | CNS Malignancies

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
EMD Serono Research & Development Institute, Inc.

Not yet recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

United States, Germany
Ruijin Hospital

Not yet recruiting

The Efficacy of Allo-HSCT in ND HR-CBF-AML

Acute Myeloid Leukemia

China
Ningbo No. 1 Hospital

Recruiting

First-line Treatment of PCNSL With the Combination of Orelabrutinib, Rituximab, and Methotrexate (ORM Regimen)

Primary Central Nervous System Lymphoma

China
University of Florida
University of Colorado, Denver; University of Miami

Not yet recruiting

Precision Administration of Anti-thymocyte Globulin With or Without Verapamil

Type 1 Diabetes

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Ductal Adenocarcinoma

United States
Guangdong Provincial People's Hospital

Not yet recruiting

Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML

Acute Myeloid Leukemia

China
Bruce Cree
Kyverna Therapeutics

Recruiting

A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis

Progressive Multiple Sclerosis

United States
Tao Lin

Not yet recruiting

Eculizumab for Prevention of Antibody-Mediated Rejection in ABO-Incompatible Living Donor Kidney Transplantation

Kidney Transplantation

China

Search clinical trials for: immunosuppressive switch (to Certican)

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