Search clinical trials for: next-generation sequencing

Total 1091 results

Fondazione Policlinico Universitario Agostino Gemelli...
Istituti Fisioterapici Ospitalieri; Istituto Nazionale Tumori IRCCS - Fondazione...

Not yet recruiting

Predictive Biomarkers Including miRNA-based Tumor Signatures in Diffuse Large B Cell Lymphoma (R/R DLBCL) (MIMOSA) (MIMOSA)

Diffuse Large B Cell Lymphoma | Relapsed Non-Hodgkin Lymphoma

Italy
GenEmbryomics Pty. Ltd

Recruiting

Whole Genome Sequencing (WGS) on IVF Embryos and Individual Patients (EmbryoWGS)

Fertility Issues | Single-Gene Defects

United States, Turkey
Royal Marsden NHS Foundation Trust

Recruiting

ORganoid GeneratioN Study for Cancer (ORIGINS)

Cancer

United Kingdom
Copenhagen University Hospital at Herlev

Recruiting

Identification and Verification of Candidate Genes Responsible for Optic Disc Drusen Development (GENODD)

Optic Disk Drusen

Denmark
Zhaoshen Li

Recruiting

Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples

Pancreatic Neoplasms | DNA Methylation | Proteome

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Non-Invasive Diagnosis of Endometrial Cancer (NIECE)

Endometrial Cancer

France
National Cancer Institute, Naples

Recruiting

Molecular Data and Their Correlations With Clinical Outcomes in Gynecological Cancer Patients. (GYNGER)

Gynecologic Cancer

Italy
University Hospital, Basel, Switzerland

Recruiting

Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases (NEUTROSKIN)

Inflammatory Dermatoses | Neutrophil-mediated Inflammatory Dermatoses

Switzerland
Number 2 Children's Hospital, Ho Chi Minh City
University Hospital, Geneva; Swiss National Science Foundation; University of... and other collaborators

Recruiting

Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam

Epileptic Encephalopathy | Whole Exome Sequencing

Vietnam
Neuromed IRCCS

Not yet recruiting

Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology

Parkinson Disease | REM Sleep Behavior Disorder

Italy
National University Hospital, Singapore
School of Computing, National University of Singapore; Cancer Science Institute...

Recruiting

Neural Network-based Treatment Decision Support Tool in Patients With Refractory Solid Organ Malignancies (DRUID)

Solid Organ Malignancies

Singapore
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus

Invasive Aspergillosis | Invasive Candidiasis

China
Heinrich-Heine University, Duesseldorf
German Cancer Aid

Not yet recruiting

Prostate Cancer Prevention Clinic for Men With Risk of Familial Prostate Cancer (ProFam-Risk)

Prostate Cancer | Familial Prostate Cancer
Radboud University Medical Center

Recruiting

Local and Systemic Immunoprofiling of Patients Diagnosed With Ulcerative Colitis (ImmUniverse)

Ulcerative Colitis Flare

Netherlands
Fubing Wang

Recruiting

Single-cell RNA Sequencing Resolves the Regulatory Role of HBV on the Hepatocellular Carcinoma Immune Microenvironment

Primary Liver Cancer | HBV

China
Centre Henri Becquerel

Not yet recruiting

Real-Time Monitoring of Circulating Tumor DNA and Study of Prognostic Factors in Patients Treated With CAR-T Cells (RT-CAR)

Diffuse Large B Cell Lymphoma

France
Magdi Yacoub Heart Foundation

Recruiting

Aswan Heart Centre - Egyptian Healthy Volunteers (AHC-EHVol)

Genetic Predisposition to Disease

Egypt
Cedars-Sinai Medical Center
National Institute on Aging (NIA)

Recruiting

Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

Obesity | Healthy Lifestyle

United States
German Cancer Research Center
University Hospital Heidelberg

Recruiting

CATCH: Implementation of Genomics-guided Precision Medicine in Metastatic Breast Cancer (CATCH)

Metastatic Breast Cancer

Germany
Guangdong Provincial People's Hospital

Recruiting

Liquid Biopsy in Advanced Oligometastatic NSCLC Receiving Surgery

Non-small Cell Lung Cancer | Oligometastatic Disease

China
Göteborg University

Recruiting

Telemonitored Fast Track Medical Sequencing for Heart Failure With Reduced Ejection Fraction (TELE-FASTER)

Heart Failure With Reduced Ejection Fraction

Sweden
The Immunobiological Technology Institute (Bio-Manguinhos)...
Oswaldo Cruz Foundation

Recruiting

Gene Sequencing as a Strategy for Identifying Genetic Factors Associated With Serious Adverse Events After Covid-19 Vaccines in Use in Brazil

Guillain-Barre Syndrome | Transverse Myelitis | Acute Disseminated Encephalomyelitis | Vaccine-induced Thrombotic Thrombocytopenia Syndrome

Brazil
National Cancer Institute (NCI)

Recruiting

A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...

Acute Lymphoblastic Leukemia | B-All

United States
University Hospital, Bordeaux

Recruiting

CML Pediatric ITK Response According to Molecular Identification at Diagnosis (CML Piramid)

Chronic Myeloid Leukemia

France
Institut de Médecine et d'Epidémiologie Appliquée...
ANRS, Emerging Infectious Diseases

Recruiting

Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST) (NGS-IST)

Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Neisseria Gonorrhoeae Infection | Sexually Transmitted Infections (Not HIV or Hepatitis)

France
Institute of Hematology & Blood Diseases Hospital
MethylGene Tech Co., Ltd. China

Recruiting

ctDNA Methylation Sequencing for Myeloma

Multiple Myeloma

China
Xuzhou Central Hospital
The Affiliated Hospital of Xuzhou Medical University

Not yet recruiting

Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty

Postoperative Delirium | Chronic Postsurgical Pain
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University Hospital... and other collaborators

Not yet recruiting

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis (TSELiOT)

Drug-resistant Tuberculosis | Cost-Benefit Analysis | HIV Coinfection

South Africa
Eunice Kennedy Shriver National Institute of Child...

Not yet recruiting

Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnancy: A Deep Phenotype Study

Cardiovascular Phenotype | Metabolic Phenotype | Hypertensive Disease | Psychological Phenotype | Audio

United States
Shenzhen Second People's Hospital

Not yet recruiting

The Value of Full-targeted Pathogen Capture Metagenomics Next Generation Sequencing in Etiological Diagnosis of Sepsis

Sepsis, Severe
Buddhist Tzu Chi General Hospital

Not yet recruiting

The Use of Molecular Radiogenomics in Non-small Cell Lung Cancer (NSCLC)

Lung Cancer
Shanghai 6th People's Hospital

Recruiting

Clinical and Molecular Biological Data Collection and Analysis in Patients With TBI

Traumatic Brain Injury

China
Tongji Hospital

Recruiting

Ambispective Cohort Study of Precision Medicine for Primary Hepatobiliary Cancer Based on Next-generation Sequencing (CCGLC-006)

Hepatocellular Carcinoma | Biliary Tract Cancer

China
Northwestern University
National Institutes of Health (NIH)

Recruiting

Heart Transplantation - Renewal (HeartRenewal)

Magnetic Resonance Imaging | Transplant, Heart

United States
Daping Hospital and the Research Institute of Surgery...

Recruiting

Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors

Gastric Cancer | Rectal Cancer | Chemotherapy Effect | Radiotherapy | Immunotherapy

China
University of Geneva, Switzerland
All India Institute of Medical Sciences, New Delhi; Swiss National Science... and other collaborators

Recruiting

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia (MPGx-INDALL)

Drug Effect | Pediatric Cancer | Adverse Drug Event | Drug Interaction | ALL, Childhood | Drug Toxicity | Toxicity, Drug | Relapse Leukemia

India
Xijing Hospital

Recruiting

Biomarker Analysis of Tislelizumab Combined With Chemotherapy for Perioperative Treatment of G/GEJ Adenocarcinoma

PD-1 | Locally Advanced Gastric Adenocarcinoma

China
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Genetic Biomarkers of Child Language Development in Taiwan: an Identification and Validation Study

Child Language

Taiwan
Australian & New Zealand Children's Haematology...
Medical Research Future Fund; Minderoo Foundation; Children's Cancer Institute...

Recruiting

Precision Medicine for Every Child With Cancer (ZERO2)

Childhood Cancer | Relapsed Cancer | Refractory Cancer | Childhood Leukemia | Childhood Solid Tumor | Childhood Brain Tumor

Australia
Shanghai Children's Hospital
Children's Hospital of Chongqing Medical University; Northwest Women's and... and other collaborators

Not yet recruiting

Newborn Sequencing Screening in China

Newborns
National Taiwan University Hospital

Recruiting

Taiwan Associated Genetic and Nongenetic Small Vessel Disease (TAG-SVD)

Stroke | Magnetic Resonance Imaging | Fabry Disease | Cerebral Small Vessel Diseases | Cadasil | HTRA1-Related Autosomal Dominant Cerebral Angiopathy | COL4A1-Related Brain Small Vessel Disease With Haemorrhage | Next-generation Sequencing

Taiwan
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

Mental Health Crises in Youth With IDDs

Intellectual Disability

United States
Far Eastern Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Polygenic Risk Score to Predict Weight Loss Intervention in Children With Obesity

Obesity | Children

Taiwan
Zhujiang Hospital

Recruiting

Omics Sequencing of Specimen Derived From Mother-Infant-Pairs

Healthy | Feces | Breast-milk Collection

China
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

Multiomic Diagnostics in Youth With Psychosis

Psychosis

United States
Xinqiao Hospital of Chongqing

Recruiting

Single-cell Sequencing of BLF to Guide the Treatment of Radiation Pneumonitis or Immune Checkpoint Inhibitor Pneumonitis

Pneumonitis

China
Region Skane

Recruiting

BioMEL- Diagnostic and Prognostic Factors in Melanoma. (BioMEL)

Melanoma | Mutation | Image | Dysplastic Nevi | Melanoma in Situ | Mole (Dermatology)

Sweden
University Hospital, Angers
Poitiers University Hospital; University Hospital, Brest; Rennes University Hospital and other collaborators

Not yet recruiting

Identification of Factors Associated With Treatment Response in Patients With Polycythemia Vera, Essential Thrombocythemia, and Pre-myelofibrosis. (BioPredictor)

Myeloproliferative Neoplasm
Sohag University
Assiut University; Kyoto University

Recruiting

Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes

Inherited BMF Syndrome

Egypt
Boston University Charles River Campus
Massachusetts General Hospital; University of Michigan; National Institute on...

Recruiting

Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech

Aphasia, Primary Progressive | Stuttering, Developmental

United States

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