Search clinical trials for: pharmacokinetic (PK)

Total 14150 results

Daiichi Sankyo, Inc.

Completed

Olmesartan Pediatric Pharmacokinetic (PK) Study

Hypertension

United States
Abdul Wali Khan University Mardan

Completed

Drug-Drug Interaction Study of Voriconazole With Clarithromycin.

Healthy

Pakistan
Bristol-Myers Squibb

Completed

Study Investigating the Pharmacokinetic Interaction Between INX-08189 and Verapamil HCL ER in Healthy Volunteers (INX-189-005)

Healthy

United States
St George's, University of London
University College, London

Recruiting

Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK) (MD-PK)

Sepsis | Critical Illness | Septic Shock | Bacteremia | Infection, Bacterial | Antibiotic Side Effect | Antibiotic Resistant Infection | Adult Children

United Kingdom
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Goal-directed LCVP Based on HP in Laparoscopic Hepatectomy

Hepatocellular Carcinoma

China
University of California, San Francisco
E-DA Hospital

Terminated

Rosuvastatin Interethnic PK Study (RST)

Statin Pharmacokinetics Pre and Post Gastric Bypass Surgery

United States, Taiwan
Novartis Pharmaceuticals

Terminated

Pharmacokinetics & Safety of Serelaxin on Top of Standard of Care Therapy in Pediatric Patients With Acute Heart Failure (RELAX-PEDS-PK)

Acute Heart Failure

United States, Germany, United Kingdom, Switzerland
Pfizer

Completed

Safety and Tolerability Study of Multiple Doses of PF-06305591

Healthy

Belgium
AstraZeneca

Completed

Pharmacokinetic Study of Daptomycin in Healthy Chinese Subjects Living in China

Healthy

China
Southeast University, China
Cttq

Unknown

Plasma and Lung Tissue Concentrations of Linezolid in Septic Shock Patients

Septic Shock
Pfizer

Completed

Study Of AG-013736 (Axitinib) In Patients With Advanced Solid Tumors

Carcinoma

Japan
Sun Yat-sen University

Unknown

Explore the Individual Treatment of Docetaxel and Paclitaxel in NSCLC, NPC and BRC by PK-guided Dosing Strategy

Breast Cancer | Non-small Cell Lung Cancer | Nasal Cancer

China
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia A (Kids ALONG)

Hemophilia A

United States, Poland, United Kingdom, Netherlands, South Africa, Hong Kong, Australia, Ireland
Hospital de Concentracion Norte de Petroleos

Completed

Electrosurgical Bipolar Plasmakinetic Vessel Sealing During Abdominal Hysterectomy: A Randomized Controlled Trial (PKAHRCT)

Abdominal Hysterectomy for Benign Disease

Mexico
Emory University
Olympus

Completed

PlasmaKinetic (PK) Button Vaporization Electrode for Treatment of Bladder Tumors (PK Button)

Bladder Cancer

United States
Novartis Pharmaceuticals

Completed

Bioavailability Study Comparing Two New Nilotinib Tablet Formulations to an Established Nilotinib Capsule Formulation in Healthy Volunteers

Healthy
Seoul National University Hospital

Not yet recruiting

PK and PD of Antibiotics for Treatment of Mycobacterium Abscessus Pulmonary Disease

Nontuberculous Mycobacterial Pulmonary Infection
Zeria Pharmaceutical

Completed

A Healthy Subject Study With Z-360 and Placebo

Healthy Volunteers

Japan
Shanxi Kangbao Biological Product Co., Ltd.
Institute of Pathogen Biology, Chinese Academy of Medical Sciences

Recruiting

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects

Hiv

China
Emergent BioSolutions

Completed

Study Evaluating the Bioequivalence of Brincidofovir Form H and Form II Tablets in Healthy Adults (BCV-001)

Smallpox

United States
Shanghai HEP Pharmaceutical Co., Ltd.

Withdrawn

A Study to Access the Efficacy in Type 2 Diabetes Mellitus on Stable Metformin

Type 2 Diabetes Patients
AstraZeneca

Completed

Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment

Hypertension

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

Locally Advanced Rectal Cancer

United States, Spain
Lupin Ltd.

Completed

A Study to Test the Safety/Tolerability of Increasing Doses of LNP1892 Versus Placebo in Healthy Male/Female Subjects

Healthy

United Kingdom
Celgene

Completed

A Study to Evaluate the Pharmacokinetics of Single Oral Doses of Ozanimod in Healthy Adult Chinese Subjects

Healthy Volunteer

China
Sihuan Pharmaceutical Holdings Group Ltd.

Completed

Evaluate Safety, Tolerability and Pharmacokinetics of Fadanafil （XZP-5849）in Chinese Healthy Adult Male Subjects

Healthy Subject

China
Depomed

Completed

Open Label Crossover Study Pharmacokinetics (PK) Study in Healthy Volunteers Receiving Various Forms of Fentanyl

Healthy
Gilead Sciences

Completed

Phase 1b Safety, Tolerability, and PK Study to Assess GS-5737 in Subjects With CF

Cystic Fibrosis

United States
Novartis Pharmaceuticals

Completed

Study to Compare the Pharmacokinetics of Mometasone Furoate Alone and in Combination With Indacaterol in Patients ≥ 6 to < 12 Years Old With Asthma

Asthma

South Africa, Hungary
Luye Pharma Group Ltd.

Completed

Pharmacokinetics, Pharmacodynamics and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX®

Prostate Cancer

China
Italfarmaco

Completed

Givinostat and Metabolites Pharmacokinetics in Urine and Plasma (Part 3)

Drug Drug Interaction

Portugal
Luye Pharma Group Ltd.

Active, not recruiting

Comparative Efficacy, Safety, PK, and Immunogenicity Study

Osteoporosis, Postmenopausal

Poland, United States, Czechia, Bulgaria, Japan
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne

Acne Vulgaris

United States, Germany, Netherlands
Celtic Pharma Development Services
PPD

Completed

TDT 067 Open Label Multi-Dose Onychomycosis Study

Onychomycosis
Universitas Padjadjaran
Radboud University Medical Center

Completed

Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability Study

Pharmacokinetics | Pharmacodynamics | Tolerability | Meningitis, Tuberculous

Indonesia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Prexasertib in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Childhood Solid Neoplasm

United States
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Completed

Bioelectrical Impedance Analysis as a Bedside Tool to Estimate Volume of Distribution of Hydrophilic Antimicrobials in Critically Ill Patients

Electric Impedance | Pharmacokinetics | Capillary Leak Syndrome

Belgium
AstraZeneca

Completed

A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet

High Risk Coronary Artery Disease

United Kingdom
Kent State University
University of Pennsylvania; Case Western Reserve University

Unknown

Stress Management for High Blood Pressure

Prehypertension

United States
Beijing Children's Hospital

Unknown

Pharmacokinetic (PK)Research on Chinese Children of Hemophilia (PK)

Pharmacokinetics

China
Central South University

Recruiting

Clinical Study of Individualized Vancomycin Dosing Based on Population PK Model

Severe Infection

China
National Institute of Allergy and Infectious Diseases...

Completed

Minocycline Pharmacokinetics (ACUMIN)

Bacterial Infection

United States
AstraZeneca

Completed

Study to Assess the Pharmacokinetics of AZD6140 After Single Dose in Healthy Japanese Male Volunteers

Healthy

Japan
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Administration of AZD8329 (AZ8329)

Healthy | Overweight | Male

United Kingdom
University of Aberdeen

Completed

The Big Breakfast Study

Obesity | Weight Loss

United Kingdom
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

Clinical Pharmacokinetics of Mitoxantrone Hydrochloride Liposome Injection in Recurrent/Refractory Lymphoma Subjects

Recurrent/Refractory Lymphoma

China
The University of Hong Kong

Completed

Pharmacokinetics of Different Mode Administration of Intranasal Dexmedetomidine

Bioavailability | Dexmedetomidine

Hong Kong
Centers for Disease Control and Prevention

Withdrawn

Pharmacokinetics of Mefloquine-Artesunate in Pregnant Women With Uncomplicated Plasmodium Falciparum Infection

Pregnancy | Malaria
Children's Hospital Medical Center, Cincinnati
Astellas Pharma Inc

Completed

Alternate Day Micafungin: A PK Study in Pediatric Patients

Fungal Infection

United States
AstraZeneca
PPD; Parexel; Covance; Iqvia Pty Ltd

Completed

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma (TATE)

Severe Uncontrolled Asthma

United States, Japan

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