Search clinical trials for: safety and toleration

Total 474881 results

Shanghai Zhongshan Hospital

Not yet recruiting

Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients

Analgesia | Mechanical Ventilation | Remifentanil | Postoperative | Oxycodone

China
Huai'an First People's Hospital
The Affiliated Hospital of Xuzhou Medical University; The First People's Hospital... and other collaborators

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL

Primary Central Nervous System Lymphoma

China
Cutting Edge SAS

Not yet recruiting

Bicentric Clinical Investigation to Assess Safety and Performance of LuxHighAdd IOL (HIGHADD)

Cataract

France
Penumbra Inc.

Recruiting

Post Market Surveillance to Evaluate the Efficacy and Safety of the INDIGO Aspiration System in Japan (JapanIndigoPMS)

Arterial Occlusion Mesenteric Artery Superior | Acute Limb Ischemia | Acute DVT of Lower Extremity

United States
Insel Gruppe AG, University Hospital Bern

Not yet recruiting

The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care

Risk Reduction | Hypobaric Hypoxia | High Altitude

Switzerland
Neudive Inc.

Not yet recruiting

To Evaluate the Efficacy and Safety of 'NDTx-01' in Patients With ASD or SCD

Autism Spectrum Disorder | Social Communication Disorder
First Affiliated Hospital of Zhejiang University

Recruiting

Efficacy and Safety of Modified Si Jun Zi Tang in Perioperative NSCLC Treatment (MSJZT-NSCLC)

Non Small Cell Lung Cancer | Perioperative Complication

China
Ipsen

Not yet recruiting

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment (ELFINITY)

Primary Biliary Cholangitis
LEO Pharma

Not yet recruiting

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

Joint Pain | Gout Flares | Joint Inflammation
Scholar Rock, Inc.

Recruiting

Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese (EMBRAZE)

Overweight and Obesity

United States
Mohammad Farris Iman Leong Bin Abdullah

Not yet recruiting

Efficacy and Safety of Low-dose Laser Acupuncture on Treating Insomnia Associated With Major Depressive Disorder

Insomnia | Major Depressive Disorder
Takeda

Not yet recruiting

A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic Pouchitis

Pouchitis

Belgium, Spain, Czechia, Italy, Israel, Croatia, Greece, Poland
Peking University

Recruiting

Real-world Study to Evaluate the Efficacy and Safety of Liposome Irinotecan

Colorectal Cancer | Solid Tumor

China
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata

Alopecia Areata

United States, Canada
Alcon Research

Not yet recruiting

Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
Biohaven Therapeutics Ltd.

Not yet recruiting

Long-term Safety and Tolerability of BHV-7000

Focal Epilepsy
National Institute of Allergy and Infectious Diseases...
KBio Inc

Not yet recruiting

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

Enterovirus Infection

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

COVID-19

United States
argenx

Not yet recruiting

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS) (ReALiSe)

Amyotrophic Lateral Sclerosis
NovoBliss Research Pvt Ltd
Winnox Cosmeceutics Sdn. Bhd

Not yet recruiting

A Clinical Study to Determine the Safety and Efficacy of Bio-Ray Knee Guard in Panelists With Varicose Vein and Knee Pain.

Varicose Veins With Self-declared Knee Pain
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients

Eosinophilic Asthma Patients
Nicolaus Copernicus University in Toruń, Collegium...

Recruiting

The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.

Knee Osteoarthritis | Knee Injuries | ACL Injury

Poland
Yale University
Usona Institute

Not yet recruiting

Open-Label Psilocybin

Safety, Feasibility, and Tolerability of Psilocybin Treatment in Individuals With Functional Impairment Due to Psychiatric Symptoms
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

A Safety and Immunogenicity Trial of a Respiratory Syncytial Virus Vaccine, LYB005 in Healthy Adults

Respiratory Syncytial Virus (RSV) | RSV Infection
Mohd Zulfakar Mazlan, MBBS

Recruiting

To Compare the Efficacy and Safety of Using oXiris and M100 During CRRT

Pneumonia | AKI - Acute Kidney Injury

Malaysia
Addpharma Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B

Essential Hypertension
Siriraj Hospital

Recruiting

The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients (PRF)

Platelet-rich Fibrin | Platelet-Rich Plasma | Female Pattern Hair Loss

Thailand
R-Pharm International, LLC
R-Pharm; Data Management 365; Keystat, LLC; Exacte Labs LLC

Recruiting

Efficacy and Safety of Olokizumab in Patients With Progressive Fibrosing Interstitial Lung Diseases

Lung Diseases, Interstitial

Russian Federation
Fujian Medical University Union Hospital

Recruiting

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder Neoplasms | Treatment Outcome | Neoplasm Recurrence, Local | Multicenter Study | Immunotherapy, Active | BCG Vaccine

China
USANA Health Sciences

Not yet recruiting

Safety and Tolerability of 2 Dietary Supplement Beverages Designed to Maintain Healthy Blood Pressure.

Tolerance | Safety Issues

United States
Shandong Suncadia Medicine Co., Ltd.

Recruiting

Safety and Tolerance of Increased Doses of HRS-5346 Tablets in Healthy Subjects

Lipoprotein Disorder Disease

China
Fudan University

Not yet recruiting

Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma，Bispecific Antibodies, HAIC, Ramucirumab

China
Sinovac Biotech Co., Ltd

Not yet recruiting

Booster Dose of sIPV Co-administered With MMR and HepA-I.

Poliomyelitis

China
Nuwacell Biotechnologies Co., Ltd.
Beijing Friendship Hospital

Not yet recruiting

A Trial to Evaluate the Safety and Efficacy of NCR300 in Preventing Recurrence of Acute Myeloid Leukemia（AML) After Transplantation

Acute Myeloid Leukemia
Sun Yat-sen University

Recruiting

Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer

Colorectal Cancer

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-Arm Clinical Trial

Carpal Tunnel Syndrome

China
XIANG YANQUN

Not yet recruiting

Efficacy and Safety of TPC+Apatinib+Camrelizumab vs GP+ Camrelizumab for High-Risk Nasopharyngeal Carcinoma: A Phase 3 Trial

Nasopharyngeal Carcinoma
Arthrosi Therapeutics

Recruiting

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients

Hyperuricemia | Gout | Arthritis, Gouty | Gout Chronic

United States, Australia, New Zealand
Angiex, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Cancer | Pancreatic Adenocarcinoma | Triple Negative Breast Cancer | Metastatic Solid Tumor | Advanced Cancer | Pancreas Cancer | Locally Advanced Carcinoma

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps

Chronic Rhinosinusitis

China
Primoris Therapeutics

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy in Patients With Burn(s)

Burns | Burn Degree Second
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (SPARKLE)

Sickle Cell Disease
Nuritas Ltd

Recruiting

A Study to Determine the Safety and Tolerability of a Range of Doses of PeptiControl in Pre-diabetic Individuals

Overweight | Pre Diabetes

India
Onconic Therapeutics Inc.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of JP-1366 in the Prevention of NSAIDs-Induced Peptic Ulcers

Peptic Ulcer

Korea, Republic of
Henan Cancer Hospital

Recruiting

An Exploratory Study of Efficacy and Safety of Iruplinalkib Tablets in Patients With ROS1 Positive Non-small Cell Lung Cancer

Non-Small Cell Lung Cancer

China
Hanmi Pharmaceutical Company Limited

Recruiting

A Study to Evaluate Efficacy and Safety of HCP1803 Compared to RLD2001-1 in Patients With Essential Hypertension (HM_APOLLO)

Hypertension

Korea, Republic of
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
Spot Biosystems Ltd.
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Not yet recruiting

Preliminary Evaluation of the Safety and Tolerability of SPOT-mRNA01 Subcutaneously Administered in Healthy Subjects

Skin Aging
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

to Evaluate the Safety/Tolerability and Pharmacokinetics, and Pharmacodynamics of DWP14012 Injection

Erosive Gastroesophageal Reflux Disease

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