Search clinical trials for: tenofovir disopropyl

Total 1150 results

Mylan Pharmaceuticals Inc

Completed

Food Study of Escitalopram Oxalate Tablets 20 mg to Lexapro® Tablets 20 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Escitalopram Oxalate Tablets 20 mg and Lexapro® Tablets 20 mg

Healthy

United States
Unity Health Toronto
Gilead Sciences; CIHR Canadian HIV Trials Network

Terminated

Virtual PrEP: Rendering PrEP Delivery More Efficient (VPrEP)

HIV Infections

Canada
University of Minnesota
American College of Clinical Pharmacy

Completed

Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract

HIV/AIDS | Menopause | Inflammation Vagina

United States
University of Miami

Active, not recruiting

PrEP at a Syringe Services Program

Hiv | Substance Use Disorders

United States
Emory University
Centers for Disease Control and Prevention

Completed

Biomarkers for Event-driven PrEP Adherence

Human Immunodeficiency Virus

United States
University of California, Los Angeles
University of Cape Town

Active, not recruiting

Evaluation of Pre-Exposure Prophylaxis (PrEP) in Pregnant and Breastfeeding Women (PrEP-PP)

HIV-I Infection

South Africa
Centre for the AIDS Programme of Research in South...
Johns Hopkins University; National Institute of Allergy and Infectious Diseases... and other collaborators

Active, not recruiting

INSTI's For The Management of HIV-associated TB (INSIGHT)

HIV/AIDS | Tuberculosis, Pulmonary

South Africa
Hektoen Institute for Medical Research
National Institute of Mental Health (NIMH)

Completed

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Demonstration Project

HIV/AIDS | Gender | Behavior and Behavior Mechanisms

United States
Hektoen Institute for Medical Research
National Institute of Mental Health (NIMH)

Completed

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Intervention Development

HIV/AIDS | Gender | Behavior and Behavior Mechanisms

United States
Hektoen Institute for Medical Research
National Institute of Mental Health (NIMH)

Completed

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study

HIV/AIDS | Gender | Behavior and Behavior Mechanisms

United States
HQ Toronto
Gilead Sciences

Active, not recruiting

Express Testing and Same-day Initiation of PrEP Study (Express-PrEP)

HIV Prevention

Canada
Janssen Research & Development, LLC

Completed

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

France, Taiwan, Canada, United States, Germany, Spain, Japan, Russian Federation, Turkey, United Kingdom
University of Oxford

Completed

Tenofovir in Pregnancy to Prevent Mother to Child Transmission of Hepatitis B. (PK-TDF)

Hepatitis B | Pregnancy | Tenofovir

Thailand
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Doravirine (MK-1439) in Participants With Human Immunodeficiency Virus 1 (HIV-1) (MK-1439-018) (DRIVE-FORWARD)

HIV-1
Gilead Sciences

Completed

Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive, HIV-1 and Hepatitis B Co-Infected Adults (Alliance)

HIV-1/HBV Co-Infection

Spain, Taiwan, Korea, Republic of, Thailand, Hong Kong, Japan, France, Turkey, Puerto Rico, Malaysia, United States, China, Dominican Republic, Greece
National Institute of Allergy and Infectious Diseases...
Gilead Sciences; ViiV Healthcare

Active, not recruiting

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

HIV Infections

Brazil, United States, South Africa, Peru, Thailand, Argentina, Vietnam
National Institute of Allergy and Infectious Diseases...
Gilead Sciences

Completed

Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum

HIV Infections

Malawi, Zimbabwe, South Africa, Uganda
Instituto de Investigación Hospital Universitario...

Completed

Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19

SARS-CoV-2 Infection

Spain
Janssen Research & Development, LLC

Terminated

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection (PENGUIN-2)

Hepatitis B, Chronic

Taiwan, Spain, Canada, Poland, United States, Japan
Quest Clinical Research
Gilead Sciences

Completed

Bictegravir/Emtricitabine/Tenofovir Alafenide Plus Doravirine

HIV-1-infection

United States
Janssen Research & Development, LLC

Completed

A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus Infection (INSIGHT)

Hepatitis B

France, United States, Belgium, United Kingdom, Poland, New Zealand, Germany, Italy, Canada
Merck Sharp & Dohme LLC

Active, not recruiting

Switch to Doravirine/Islatravir (DOR/ISL) in Human Immunodeficiency Virus 1 (HIV-1) Participants Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-018)

HIV Infection

United States, Australia, Austria, Canada, Finland, France, Germany, Italy, Japan, Puerto Rico, Spain
Gilead Sciences

Active, not recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed Children

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Uganda, South Africa, Zimbabwe
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
The HIV Netherlands Australia Thailand Research...
Police General Hospital; Faculty of Medical Sciences, Radboud University of... and other collaborators

Completed

Switching From Protease Inhibitor/Ritonavir to Generic Single Tablet Regimen of Tenofovir Alafenamide/Emtricitibine/Dolutegravir

HIV

Thailand
Merck Sharp & Dohme LLC

Completed

Effects of Switching From ATRIPLA™ (Efavirenz, Tenofovir, Emtricitabine) to MK-1439A (Doravirine, Tenofovir, Lamivudine) in Virologically-Suppressed Participants (MK-1439A-028)

HIV-1 | Central Nervous System
University of Washington
University of Colorado, Denver; Gilead Sciences; Kenya Medical Research Institute

Completed

The Women TAF-FTC Benchmark Study

HIV Infections

Kenya
Fundacion IDEAA
ViiV Healthcare

Completed

Efficacy of Dolutegravir Plus Lamivudine in HIV-1-infected Treatment-naïve Adults Without a Baseline Genotyping Test (D2ARLING)

Hiv | HIV-1-infection

Argentina
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
ViiV Healthcare
GlaxoSmithKline

Completed

A Study to Determine Safety and Efficacy of Dolutegravir/Abacavir/Lamivudine (DTG/ABC/3TC) in Human Immunodeficiency Virus (HIV)-1 Infected Antiretroviral Therapy (ART) Naïve Women (ARIA)

HIV Infections | Infection, Human Immunodeficiency Virus

United States, France, Spain, United Kingdom, Canada, Thailand, Italy, Portugal, Russian Federation, Mexico, Argentina, South Africa, Puerto Rico
University of Alberta
Merck Sharp & Dohme LLC

Completed

Combination Antiretroviral Therapy (cART) for PBC

Primary Biliary Cholangitis

Canada
Gilead Sciences
Vir Biotechnology, Inc.

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)

Chronic Hepatitis B

Hong Kong, Korea, Republic of, Denmark, Australia, Thailand, Singapore, United Kingdom, New Zealand
IRCCS San Raffaele
Gilead Sciences

Terminated

Switch From Dual Regimens Based on Dolutegravir Plus a Reverse Transcriptase Inhibitor to E/C/F/TAF in Virologically Suppressed, HIV-1 Infected Patients (Be-OnE) (Be-OnE)

HIV-1-infection

Italy
Mahidol University

Completed

The Effects of Vitamin D and Calcium Supplementation to Parathyroid Hormone in CHB Patients Treated With TDF (TDF)

Chronic Hepatitis B Virus | Vitamin D | Tenofovir Disoproxil Fumarate | Parathyroid Hormone

Thailand
Fundacion SEIMC-GESIDA

Active, not recruiting

Simplified Model of Linkage and Retention to Care, Using a Mobile Unit and a Same-day Test and Treat Approach Among Excluded Population. (SIMPLIFIED) (SIMPLIFIED)

HIV Infections

Spain
Weill Medical College of Cornell University
Gilead Sciences

Active, not recruiting

Switch to Bictegravir/Emtricitabine/Tenofovir Alafenamide After Renal Transplant

HIV Infections | Renal Transplant Rejection

United States
Centre Hospitalier Annecy Genevois

Completed

Evaluation of Pre-Exposure Prophylaxis Against HIV in Alpine Region (PrEP2A)

HIV Seronegativity | Pre-Exposure Prophylaxis | Drug Combination

France
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Optimization of a Tenofovir Enema for HIV Prevention (DREAM-01)

HIV Prevention

United States
Chinese University of Hong Kong

Completed

HIV Pre-exposure Prophylaxis Implementation Hong Kong Study

HIV Infections

Hong Kong
Population Council

Active, not recruiting

A Crossover Adherence and Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention

HIV Infections

South Africa
Centre de Recherches et d'Etude sur la Pathologie...

Completed

Specific Anti-HBV Vaccine Response After Vaccination in Patients Requiring Anti-CD20 Monoclonal Antibodies (HepB20)

HBV

France
Eastern Virginia Medical School
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Project ADHERE: Clinical Proof-of-Concept of a Tenofovir (TFV) Aptamer-Based Biosensor

HIV/AIDS | Adherence, Medication | Drug Use

United States
Fundacion SEIMC-GESIDA

Active, not recruiting

Study to Evaluate the Efficacy and Safety of a Rilpivarine-based Antiretroviral Tratment Regimen in HIV- Infected Patients With Liver Metabolic Disease Who Maintain Udetectable HIV Viral Load (MAFALDA-R)

HIV Infections | Fatty Liver Disease

Spain
Guangxi Medical University

Completed

Adjuvant Entecavir or Tenofovir for Postoperative HBV-HCC

Hepatocellular Carcinoma

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Active, not recruiting

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer (REACTION)

Gastroesophageal Cancer | Immune Checkpoint Inhibition

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Active, not recruiting

Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer

Gastric Cancer | Esophageal Cancer | GastroEsophageal Cancer

United States
Bristol-Myers Squibb

Terminated

Open-Label Study Comparing Efficacy and Safety of ATV/RTV+3TC With ATV/RTV+TDF/FTC in HIV-Infected, Treatment Naïve Subjects, Followed by Treatment With ATV/RTV+3TC

HIV
National Institute of Neurological Disorders and...

Completed

HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States
University of Washington
University of Colorado, Denver; National Institute of Allergy and Infectious... and other collaborators

Active, not recruiting

The Women TDF-FTC Benchmark Study

HIV Infections

Kenya

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