Search clinical trials for: Predictive Genetic Signatures

Total 20167 results

National Center for Research Resources (NCRR)
James Whitcomb Riley Hospital for Children

Completed

Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes

Thrombocytopenia | Dyskeratosis Congenita | Fanconi's Anemia | Shwachman Syndrome
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Completed

Randomized Study of Pancrelipase With Bicarbonate (PANCRECARB) Capsules in Reducing Steatorrhea in Patients With Cystic Fibrosis

Cystic Fibrosis
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia

Familial Hypercholesterolemia
National Center for Research Resources (NCRR)
University of Pittsburgh

Unknown

Phase II Study of Glucocerebrosidase in Patients With Gaucher Disease

Gaucher's Disease

United States
National Center for Research Resources (NCRR)
Children's Hospital Medical Center, Cincinnati

Unknown

Genetic Study of Insulin-Like Growth Factor-I Receptor Mutations in Patients With Intrauterine Growth Retardation

Intrauterine Growth Retardation

United States
National Institute of Neurological Disorders and...
Baylor College of Medicine

Completed

Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes

Prader-Willi Syndrome | DiGeorge Syndrome | Williams Syndrome | Angelman Syndrome | Smith-Magenis Syndrome | Chromosome Abnormalities | Shprintzen Syndrome

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria

Porphyria
University of Minnesota

Unknown

Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia
National Center for Research Resources (NCRR)
Children's Hospital Medical Center, Cincinnati

Unknown

Phase II Pilot Study to Compare the Bioavailability of Buffered, Enteric-Coated Ursodiol With Unmodified Ursodiol for Chronic Cholestatic Liver Disease and Cystic Fibrosis-Associated Liver Disease

Gastrointestinal Diseases | Cystic Fibrosis | Cholestasis

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Pilot Study of Extracorporeal Phototherapy for Epidermolysis Bullosa Acquisita

Epidermolysis Bullosa Acquisita
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Stem Cell Transplantation (SCT) for Genetic Diseases

Thrombocytopenia | Inborn Errors of Metabolism | Metachromatic Leukodystrophy | Fanconi's Anemia | Thalassemia Major | Pure Red-Cell Aplasia

United States
Eunice Kennedy Shriver National Institute of Child...
University of Minnesota

Completed

Phase I/II Study of Retroviral-Mediated Transfer of Iduronate-2-Sulfatase Gene Into Lymphocytes of Patients With Mucopolysaccharidosis II (Mild Hunter Syndrome)

Mucopolysaccharidosis II

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Placebo-Controlled, Crossover Study of Soy Protein Isolate for Hereditary Hemorrhagic Telangiectasia

Hereditary Hemorrhagic Telangiectasia
Royal Brompton & Harefield NHS Foundation Trust
CORDA, The Heart Charity; Apotex Inc.; The Cooley's Anemia Foundation,; The UK...

Unknown

Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major

Beta-Thalassemia

Italy
National Center for Research Resources (NCRR)

Unknown

Quantification of Pulmonary Neutrophil Activity in Cystic Fibrosis Using Radiolabeled Fluorodeoxyglucose and PET Imaging

Cystic Fibrosis

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles; National Institute of Neurological Disorders...

Completed

Long-Term Study of Cerebral Glucose Metabolism in Huntington's Disease

Huntington's Disease
Medical Research Laboratories International

Terminated

Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy

Familial Hypercholesterolemia

Netherlands, United States, Norway
Nucryst Pharmaceuticals

Completed

Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)

Eczema | Atopic Dermatitis

United States
University of Pittsburgh

Completed

The Effects of AZT and Ibuprofen on HIV-Infected Patients With Hemophilia

HIV Infections | Hemophilia A

United States
National Center for Research Resources (NCRR)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Establishment of the National Epidermolysis Bullosa Registry

Epidermolysis Bullosa
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Systemic Amyloidosis Presentation and Prognosis

Amyloidosis

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Multicenter Study of Nontuberculous Mycobacteria in Cystic Fibrosis Patients

Cystic Fibrosis | Atypical Mycobacterium Infection
National Center for Research Resources (NCRR)
University of Pittsburgh

Terminated

Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

Alpha 1-Antitrypsin Deficiency

United States
National Center for Research Resources (NCRR)
University of Rochester

Completed

Phase II Pilot Study of Olsalazine for Ankylosing Spondylitis

Ankylosing Spondylitis
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism

Pseudohypoparathyroidism
National Center for Research Resources (NCRR)
University of Michigan

Completed

Phase II Study of the Enzyme Inhibitor NTBC for Tyrosinemia Type I

Tyrosinemia, Type I
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Establishment of a Database for Long-Term Monitoring of Patients With Nephropathic Cystinosis

Cystinosis

United States
National Center for Research Resources (NCRR)
University of Utah

Terminated

Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis

Cystic Fibrosis

United States
Fairview University Medical Center

Unknown

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Mucopolysaccharidosis I | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Pulmonary Complications | Fucosidosis | Globoid Cell Leukodystrophy | Gaucher's Disease | Mannosidosis | I Cell Disease

United States
Ribozyome

Completed

Gene Therapy in HIV-Positive Patients With Non-Hodgkin's Lymphoma

HIV Infections | Lymphoma, Non-Hodgkin

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder

Tourette Syndrome
National Center for Research Resources (NCRR)
University of Texas

Completed

Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias

Porphyria

United States
National Center for Research Resources (NCRR)
Cystic Fibrosis Foundation

Suspended

Pressure Support Ventilation During CF Exacerbations

Cystic Fibrosis

United States
National Center for Research Resources (NCRR)

Completed

Vitamin D Metabolism and the Williams Syndrome

Williams Syndrome

United States
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders

Paralysis, Hyperkalemic Periodic | Paramyotonia Congenita | Hypokalemic Periodic Paralysis
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

Heart Defects, Congenital | Tetralogy of Fallot | Pulmonary Valve Stenosis | Hypoparathyroidism | Pulmonary Atresia | Conotruncal Cardiac Defects
National Center for Research Resources (NCRR)
University of Michigan

Completed

Pilot Study of Familial Nonsyndromal Mondini Dysplasia

Mondini Dysplasia

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Evaluation of Fanconi Syndrome and Cystinosis

Fanconi Syndrome | Cystinosis
National Center for Research Resources (NCRR)

Completed

The Safety and Efficacy of Adjunct Carvedilol in Children With Moderate Heart Failure

Heart Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cooperative Study of The Clinical Course of Sickle Cell Disease

Anemia, Sickle Cell | Blood Disease
National Center for Research Resources (NCRR)
Icahn School of Medicine at Mount Sinai

Completed

Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone

Stenosis | Histiocytoma

United States
National Center for Research Resources (NCRR)
Vanderbilt University Medical Center

Completed

Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic Fibrosis

Bacterial Infections | Cystic Fibrosis
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
Walter Reed Army Institute of Research (WRAIR)

Completed

A Study to See Whether Two HIV Vaccines Are Safe and Can Prevent HIV Infection

HIV Infections | HIV Seronegativity

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Study of the Nutritional, Metabolic, and Body Composition Profile in Children and Adolescents With Epidermolysis Bullosa

Epidermolysis Bullosa
National Center for Research Resources (NCRR)
University of Texas

Unknown

Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis

Systemic Sclerosis

United States
National Center for Research Resources (NCRR)
University of Rochester

Completed

Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome

Tourette Syndrome
National Center for Research Resources (NCRR)
University of Texas

Completed

Study of the Pathogenesis of Porphyria Cutanea Tarda

Porphyria Cutanea Tarda

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase II Pilot Study of Octreotide, a Somatostatin Octapeptide Analog, for Gastrointestinal Hemorrhage in Hormone-Refractory Hereditary Hemorrhagic Telangiectasia and Senile Ectasia

Hereditary Hemorrhagic Telangiectasia | Ectasia
Research Institute for Genetic and Human Therapy

Completed

Safety and Effectiveness of Combining Hydroxyurea (HU) With Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults

HIV Infections

United States

Search clinical trials for: Predictive Genetic Signatures

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