Search clinical trials for: germline genetic testing

Total 23509 results

National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Pilot Study of Extracorporeal Phototherapy for Epidermolysis Bullosa Acquisita

Epidermolysis Bullosa Acquisita
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Stem Cell Transplantation (SCT) for Genetic Diseases

Thrombocytopenia | Inborn Errors of Metabolism | Metachromatic Leukodystrophy | Fanconi's Anemia | Thalassemia Major | Pure Red-Cell Aplasia

United States
Eunice Kennedy Shriver National Institute of Child...
University of Minnesota

Completed

Phase I/II Study of Retroviral-Mediated Transfer of Iduronate-2-Sulfatase Gene Into Lymphocytes of Patients With Mucopolysaccharidosis II (Mild Hunter Syndrome)

Mucopolysaccharidosis II

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Placebo-Controlled, Crossover Study of Soy Protein Isolate for Hereditary Hemorrhagic Telangiectasia

Hereditary Hemorrhagic Telangiectasia
Royal Brompton & Harefield NHS Foundation Trust
CORDA, The Heart Charity; Apotex Inc.; The Cooley's Anemia Foundation,; The UK...

Unknown

Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major

Beta-Thalassemia

Italy
National Center for Research Resources (NCRR)

Unknown

Quantification of Pulmonary Neutrophil Activity in Cystic Fibrosis Using Radiolabeled Fluorodeoxyglucose and PET Imaging

Cystic Fibrosis

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles; National Institute of Neurological Disorders...

Completed

Long-Term Study of Cerebral Glucose Metabolism in Huntington's Disease

Huntington's Disease
Medical Research Laboratories International

Terminated

Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy

Familial Hypercholesterolemia

Netherlands, United States, Norway
Nucryst Pharmaceuticals

Completed

Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)

Eczema | Atopic Dermatitis

United States
University of Pittsburgh

Completed

The Effects of AZT and Ibuprofen on HIV-Infected Patients With Hemophilia

HIV Infections | Hemophilia A

United States
National Center for Research Resources (NCRR)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Establishment of the National Epidermolysis Bullosa Registry

Epidermolysis Bullosa
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Systemic Amyloidosis Presentation and Prognosis

Amyloidosis

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Multicenter Study of Nontuberculous Mycobacteria in Cystic Fibrosis Patients

Cystic Fibrosis | Atypical Mycobacterium Infection
National Center for Research Resources (NCRR)
University of Pittsburgh

Terminated

Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

Alpha 1-Antitrypsin Deficiency

United States
National Center for Research Resources (NCRR)
University of Rochester

Completed

Phase II Pilot Study of Olsalazine for Ankylosing Spondylitis

Ankylosing Spondylitis
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism

Pseudohypoparathyroidism
National Center for Research Resources (NCRR)
University of Michigan

Completed

Phase II Study of the Enzyme Inhibitor NTBC for Tyrosinemia Type I

Tyrosinemia, Type I
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Establishment of a Database for Long-Term Monitoring of Patients With Nephropathic Cystinosis

Cystinosis

United States
National Center for Research Resources (NCRR)
University of Utah

Terminated

Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis

Cystic Fibrosis

United States
Merck Sharp & Dohme LLC

Completed

The Effectiveness of HIV RNA Viral Load Testing in Determining Treatment Type in HIV-Infected Patients

HIV Infections

United States
Fairview University Medical Center

Unknown

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Mucopolysaccharidosis I | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Pulmonary Complications | Fucosidosis | Globoid Cell Leukodystrophy | Gaucher's Disease | Mannosidosis | I Cell Disease

United States
Ribozyome

Completed

Gene Therapy in HIV-Positive Patients With Non-Hodgkin's Lymphoma

HIV Infections | Lymphoma, Non-Hodgkin

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder

Tourette Syndrome
National Center for Research Resources (NCRR)
University of Texas

Completed

Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias

Porphyria

United States
National Center for Research Resources (NCRR)
Cystic Fibrosis Foundation

Suspended

Pressure Support Ventilation During CF Exacerbations

Cystic Fibrosis

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Prenatal Testing: Amniocentesis Versus Transabdominal Chorionic Villus Sampling (TA CVS)

Pregnancy
National Center for Research Resources (NCRR)

Completed

Vitamin D Metabolism and the Williams Syndrome

Williams Syndrome

United States
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders

Paralysis, Hyperkalemic Periodic | Paramyotonia Congenita | Hypokalemic Periodic Paralysis
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

Heart Defects, Congenital | Tetralogy of Fallot | Pulmonary Valve Stenosis | Hypoparathyroidism | Pulmonary Atresia | Conotruncal Cardiac Defects
National Center for Research Resources (NCRR)
University of Michigan

Completed

Pilot Study of Familial Nonsyndromal Mondini Dysplasia

Mondini Dysplasia

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Evaluation of Fanconi Syndrome and Cystinosis

Fanconi Syndrome | Cystinosis
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cooperative Study of The Clinical Course of Sickle Cell Disease

Anemia, Sickle Cell | Blood Disease
National Center for Research Resources (NCRR)
Icahn School of Medicine at Mount Sinai

Completed

Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone

Stenosis | Histiocytoma

United States
National Center for Research Resources (NCRR)
Vanderbilt University Medical Center

Completed

Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic Fibrosis

Bacterial Infections | Cystic Fibrosis
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
Walter Reed Army Institute of Research (WRAIR)

Completed

A Study to See Whether Two HIV Vaccines Are Safe and Can Prevent HIV Infection

HIV Infections | HIV Seronegativity

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Study of the Nutritional, Metabolic, and Body Composition Profile in Children and Adolescents With Epidermolysis Bullosa

Epidermolysis Bullosa
National Center for Research Resources (NCRR)
University of Texas

Unknown

Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis

Systemic Sclerosis

United States
National Center for Research Resources (NCRR)
University of Rochester

Completed

Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome

Tourette Syndrome
National Center for Research Resources (NCRR)
University of Texas

Completed

Study of the Pathogenesis of Porphyria Cutanea Tarda

Porphyria Cutanea Tarda

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase II Pilot Study of Octreotide, a Somatostatin Octapeptide Analog, for Gastrointestinal Hemorrhage in Hormone-Refractory Hereditary Hemorrhagic Telangiectasia and Senile Ectasia

Hereditary Hemorrhagic Telangiectasia | Ectasia
Research Institute for Genetic and Human Therapy

Completed

Safety and Effectiveness of Combining Hydroxyurea (HU) With Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase II Study of the Pathophysiology and Treatment With Enalapril and Polystyrene Sulfonate for Pseudohypoaldosteronism, Type I

Pseudohypoaldosteronism
RespireRx
FRAXA Research Foundation

Completed

Effects of CX516 on Functioning in Fragile X Syndrome and Autism

Fragile X Syndrome | Autism

United States
National Center for Research Resources (NCRR)
Children's Hospital of Philadelphia

Completed

Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major

Osteoporosis | Osteopenia | Thalassemia Major
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria

Porphyria
Dana-Farber Cancer Institute

Unknown

Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia

Fanconi's Anemia

United States
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Phase I Study of the Third Generation Adenovirus H5.001CBCFTR in Patients With Cystic Fibrosis

Cystic Fibrosis
National Center for Research Resources (NCRR)
University of Vermont

Completed

Studies of Hereditary Hemorrhagic Telangiectasia

Telangiectasia, Hereditary Hemorrhagic
Eunice Kennedy Shriver National Institute of Child...
Baylor College of Medicine

Completed

Nutritional Aspects of Rett Syndrome

Rett Syndrome

Search clinical trials for: germline genetic testing

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Romania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations