Search clinical trials for: Antineoplastic Agents

Total 187659 results

Novartis Pharmaceuticals

Terminated

Phase II of AUY922 in Second-line Gastric Cancer in Combination With Trastuzumab in HER2 Positive Patients

Advanced Gastric Cancer

Spain, Belgium, France, Italy, United States, Korea, Republic of, Japan, Germany
amy tiersten
AstraZeneca; Eisai Inc.

Completed

Durvalumab and Eribulin in Her2-negative Metastatic Breast Cancer and Recurrent Ovarian Cancer

Recurrent Ovarian Cancer | HER2-Negative Metastatic Breast Cancer

United States
University of Wisconsin, Madison
Amgen

Terminated

Trial of Panitumumab/Cisplatin/Fluorouracil Combined With Radiation in Esophageal Cancer

Cancer

United States
Assuntina Sacco, M.D.
Pfizer

Terminated

Avelumab for Recurrent/Metastatic Nasopharyngeal Cancer

Nasopharyngeal Cancer

United States
Hoffmann-La Roche

Completed

A Study of SC Administration of Trastuzumab (Herceptin) by SID at Home in HER2-Positive EBC Participants (HOMERUS)

Breast Cancer

Netherlands
Effector Therapeutics
Pfizer; Merck KGaA, Darmstadt, Germany

Completed

A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer

Microsatellite Stable Relapsed or Refractory Colorectal Cancer

United States
Institut Curie
Centre Leon Berard; Institut Bergonié; Hoffmann-La Roche; University Hospital,... and other collaborators

Completed

Intrathecal Trastuzumab Administration in Metastatic Breast Cancer Patients Developing Carcinomatous Meningitis (HIT)

Metastatic Breast Cancer | Carcinomatous Meningitis

France
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC; National Institute for Health Research, United Kingdom

Terminated

A Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer (PAPAYA)

Cervix Cancer

United Kingdom
National Cancer Institute, Slovakia
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in Refractory Testicular Germ Cell Cancer.

Neoplasms | Gonadal Disorders | Neoplasms, Germ Cell and Embryonal | Testicular Neoplasms | Testicular Diseases | Antineoplastic Agents | Molecular Mechanisms of Pharmacological Action

Slovakia
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Unknown

A Study of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Fujian Cancer Hospital
Zhejiang Cancer Hospital; Sun Yat-sen University; Jiangxi Provincial Cancer Hospital and other collaborators

Unknown

Nimotuzumab for Recurrent Nasopharyngeal Carcinoma

Recurrent Nasopharyngeal Carcinoma

China
Groupe Oncologie Radiotherapie Tete et Cou

Completed

Reirradiation and Erbitux in the HNSCC

Head and Neck Cancer Squamous Cell

France
Glostrup University Hospital, Copenhagen
Genzyme, a Sanofi Company

Unknown

The Effect of Alemtuzumab on the Blood-brain-barrier and the Brain's Metabolism in Multiple Sclerosis Patients

Multiple Sclerosis

Denmark
Rambam Health Care Campus
Merck KGaA, Darmstadt, Germany

Completed

Does Acne Rash During Adolescence Predict Skin Reaction to Cetuximab

Colorectal Cancer Metastatic

Israel
Peregrine Pharmaceuticals

Completed

A Safety and Efficacy Study of Bavituximab Plus Docetaxel in Patients With Advanced Breast Cancer

Breast Cancer

Georgia
Vanderbilt University
National Cancer Institute (NCI)

Completed

Cetuximab in Treating Patients With Ménétrier Disease at High Risk of Developing Stomach Cancer

Gastric Cancer | Precancerous Condition

United States
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

Cetuximab in Refractory Colorectal Cancer With K-RAS Mutated and Favorable FcγRIIa (CD32) Genotype (MUTEX)

Colorectal Neoplasms

Spain
Hoffmann-La Roche

Completed

Human Epidermal Growth Factor Receptor 2 (HER-2) Status in Gastric and Gastro-Esophageal Junction (GEJ) Carcinoma

Gastric Cancer, Gastroesophageal Junction Cancer

France
University of Pittsburgh
Amgen

Withdrawn

Trial of Radiotherapy and Panitumumab in Salivary Gland Malignancies

Adenoma, Pleomorphic | Mixed Salivary Gland Tumor | Salivary Gland Tumor, Mixed | Syringoma, Chondroid

United States
Eli Lilly and Company

Completed

Study to Evaluate the Effect of Cetuximab on Corrected QT (QTc) Interval Changes in Patients With Advanced Malignancies From Solid Tumors

Advanced Cancer

Puerto Rico, United States
University Health Network, Toronto

Completed

A Safety and Feasibility Study of Mitotane in Prostate Cancer

Prostate Cancer

Canada
Hellenic Cooperative Oncology Group

Completed

Study of Panitumumab-Capecitabine-Oxaliplatin In Wild-Type K-Ras Metastatic Colorectal Cancer Patients

Colorectal Cancer

Greece
Genzyme, a Sanofi Company

Terminated

Phase I/II Study of CAMPATH in Patients With Relapsing or Refractory Non-Hodgkin's Lymphoma

Non-Hodgkins Lymphoma

United States
CABYC
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea

Terminated

Alemtuzumab Use (MabCampath®) in Hematopoietic Transplant of Unrelated Donor With Reduced Intensity Conditioning

Graft Versus Host Disease

Spain
Merck KGaA, Darmstadt, Germany

Completed

Prospective, Post Marketing Surveillance Study On Erbitux® (Cetuximab) in Patients With Locally Advanced or Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck in Korea

Head and Neck Cancer

Korea, Republic of
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Monoclonal Antibody in Treating Patients With Acute Myelogenous Leukemia

Leukemia

United States
Peking University

Unknown

Study of Nimotuzumab to Treat Esophageal Squamous Cell Carcinoma.

Esophageal Squamous Cell Cancer

China
AltaRex

Unknown

Monoclonal Antibody Therapy in Treating Patients With Residual Disease From Stage III or Stage IV Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer Following Surgery and Chemotherapy

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United States, Canada
Maastricht University Medical Center

Completed

Real World Efficiency of Trastuzumab in Early Breast Cancer

Breast Cancer

Netherlands
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Vaccine Therapy in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United States
Karolinska University Hospital

Unknown

Randomised Phase II, Cetuximab in Combination With 5FU and Cisplatin or Carboplatin Versus Cetuximab in Combination With Paclitaxel and Carboplatin for Treatment of Patients With Metastatic Squamous Cell Carcinoma of the Head and Neck (CETMET)

Squamous Cell Carcinoma of the Head and Neck

Denmark, Sweden
University of Göttingen

Completed

CHO(E)P-14 Followed by Alemtuzumab Consolidation in Peripheral T Cell Lymphoma

Peripheral T-Cell Lymphoma
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Alemtuzumab in Treating Patients With Waldenstrom's Macroglobulinemia

Lymphoma

United States, Australia, United Kingdom, Canada, France
Oncoscience AG
Heinrich-Heine University, Duesseldorf; University of Kiel; Johann Wolfgang Goethe... and other collaborators

Completed

Nimotuzumab in Adults With Glioblastoma Multiforma

Adults With Glioblastoma Multiforma

Germany
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

T-Cell Response in Patients Receiving Trastuzumab and/or Chemotherapy for HER2-Positive Solid Tumors

Sarcoma | Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
UCB Pharma

Completed

Study of Epratuzumab in Serologically-positive Systemic Lupus Erythematosus (SLE) Patients With Active Disease

Systemic Lupus Erythematosus

United States, Poland, Spain, Belgium, India, Ukraine, Brazil, United Kingdom, Hungary, Lithuania, Hong Kong
Heidelberg University

Completed

Radiation Plus Cetuximab in Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

Germany
Eli Lilly and Company
Bristol-Myers Squibb

Completed

A Study of Cetuximab in Patients Who Have Stage IV Colorectal Cancer

Colorectal Neoplasms

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effect of Corticosteroids on Mylotarg® Infusion-Related Adverse Events in Patients With Leukemia

Leukemia, Myelocytic, Acute | Infusions, Intravenous
Peregrine Pharmaceuticals

Completed

Repeat-Dose Study of Bavituximab in Patients With Chronic Hepatitis C

Hepatitis C

United States
ARCAGY/ GINECO GROUP
Hoffmann-La Roche

Terminated

Addition of Herceptin to a Carboplatin-Paclitaxel Regimen in Patients With Ovarian Cancer

Ovarian Cancer

France
Karolinska University Hospital
Schering Nordiska AB

Completed

Study to Evaluate the Safety of Subcutaneous Alemtuzumab in Patients With B-Cell Chronic Lymphocytic Leukemia

B-CLL

Sweden
Latin American Cooperative Onco-Haematology Group...

Unknown

Study of Alemtuzumab to Treat Advanced Mycosis Fungoides/Sezary Syndrome

Mycosis Fungoides | Sezary Syndrome

Peru
Lucia Del Mastro,MD

Completed

Neoadjuvant 5-fluorouracil, Epirubicin and Cyclophosphamide (FEC) Followed by Weekly Paclitaxel and Trastuzumab in Her2 Positive Breast Cancer

HER-2 Positive Breast Cancer

Italy
Amsterdam UMC, location VUmc
Amgen

Completed

Chemoradiation With Gemcitabine in Combination With Panitumumab for Patients With Locally Advanced Pancreatic Cancer (Vectibix)

Pancreatic Cancer

Netherlands
Institut National de la Santé Et de la Recherche...

Completed

Treatment of Idiopathic Pulmonary Fibrosis With Long Acting Octreotide (FIBROSAND)

Idiopathic Pulmonary Fibrosis
Maastricht Radiation Oncology
Merck Sharp & Dohme LLC; Academisch Ziekenhuis Maastricht

Completed

Phase I Cetuximab and Concurrent Radio-chemotherapy

Non-small Cell Lung Cancer

Netherlands
National Center for Research Resources (NCRR)
Yale University

Completed

Phase II Pilot Study of Octreotide, a Somatostatin Octapeptide Analog, for Gastrointestinal Hemorrhage in Hormone-Refractory Hereditary Hemorrhagic Telangiectasia and Senile Ectasia

Hereditary Hemorrhagic Telangiectasia | Ectasia
The University of Texas Health Science Center at...
National Cancer Institute (NCI)

Completed

Bizelesin in Treating Patients With Advanced Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Safety and Tolerability of Inotuzumab Ozogamicin (CMC-544) in Japanese Patients With B-cell Non-Hodgkin's Lymphoma (NHL)

Lymphoma, B-Cell

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