Search clinical trials for: immunoglobulins, intravenous

Total 7428 results

National Heart, Lung, and Blood Institute (NHLBI)

Completed

Transfusion-Transmitted Cytomegalovirus Prevention in Neonates

Cytomegalovirus Infections | Blood Transfusion
Hospital San Jose Tec de Monterrey
Inosan Biopharma

Completed

Safety and Efficacy of Anti-SARS-CoV-2 Equine Antibody F(ab')2 Fragments (INOSARS) for Adult Patients With Mild COVID-19

COVID-19

Mexico
Weill Medical College of Cornell University
Columbia University; New York Presbyterian Hospital

Completed

A Trial of Antenatal Treatment of Alloimmune Thrombocytopenia

Alloimmune Thrombocytopenia | Fetal Alloimmune Thrombocytopenia

United States
Centre Hospitalier Universitaire de Besancon
Ministry of Health, France; Saint-Louis Hospital, Paris, France

Completed

Intravenous Immunoglobulins in Severe and Refractory Solar Urticaria (IGUS)

Solar Urticaria

France
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

Anti-HIV Immunoglobulin (HIVIG) in Prevention of Maternal-Fetal HIV Transmission (Pediatric ACTG Protocol 185)

HIV Infections | Acquired Immunodeficiency Syndrome | Disease Transmission, Vertical
Centre Hospitalier Universitaire de Saint Etienne
Laboratoire français de Fractionnement et de Biotechnologies

Completed

Randomized Open-label Trial to Compare Efficacy and Tolerance of Corticosteroids and IVIg (PRNC)

Demyelinating Polyneuropathy

France
University of Giessen

Withdrawn

Intravenous Immunoglobulins in Complex-regional Pain Syndrome (PAINLESS)

Complex Regional Pain Syndrome Type 1

Germany
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Interruption of Maternal-to-Infant Transmission of Hepatitis B by Means of Hepatitis B Immune Globulin

Liver Diseases | Hepatitis B | Hepatitis, Viral, Human
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Completed

Inpatient Treatment of COVID-19 With Anti-Coronavirus Immunoglobulin (ITAC)

COVID-19 | COVID | SARS-CoV-2 | SARS (Severe Acute Respiratory Syndrome)

Spain, United States, Denmark, United Kingdom, Greece, Japan, Nigeria
Queen Saovabha Memorial Institute

Completed

Human Rabies Immunoglobulin (HRIG)- Dosage Determination and Interference With the Active Immune Response

Rabies

Thailand
Azienda Ospedaliera Universitaria Integrata Verona

Completed

Intravenous Immunoglobulins for Post-Polio Syndrome

Post-polio Syndrome
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Cardiff University; Northern... and other collaborators

Terminated

A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis (STRIVE)

Neuromyelitis Optica | Myelitis, Transverse

United Kingdom
Octapharma

Completed

The Effect of Subcutaneous Immunoglobulin Gammanorm on the Distribution of IgG Subclasses and on Immunity of Patients With Secondary Immunodeficiency

Secondary Immune Deficiency

France
Centre Hospitalier Universitaire de Pointe-a-Pitre

Unknown

Clinical Evaluation of Anti-CHIKV Hyperimmune Intravenous Immunoglobulins (CHIKIVIG-01)

Chikungunya Virus Infection

France
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

A Study to Assess the Tolerability, Safety, and Pharmacokinetics of Subcutaneous Immune Globulin Infusion 10% (Human) With Recombinant Human Hyaluronidase (HYQVIA/HyQvia) With Ramp-up and No Ramp-up Dosing in Healthy Adult Participants

Healthy Volunteers

United States
Grifols Therapeutics LLC

Completed

Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients

Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Wiskott-Aldrich Syndrome | Agammaglobulinemia | Immunologic Deficiency Syndrome

Canada, United States
NYU Langone Health

Terminated

Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigus

Pemphigus Vulgaris

United States
Entera Health, Inc

Terminated

To Evaluate SBI in the Dietary Management of Mild to Moderate Crohn's Disease

Crohn's Disease

United States
University of Oxford
University College London Hospitals; CSL Behring; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis (IgNiTE)

Encephalitis

United Kingdom
Instituto Grifols, S.A.
Grifols Biologicals, LLC

Completed

A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease (AMBAR)

Alzheimer's Disease

Spain, United States
Emergent BioSolutions

Completed

Study in Healthy Volunteers Evaluating Safety and Pharmacokinetics of Zika Virus Immune Globulin (ZIKV-IG)

Zika Virus Infection | Zika Virus Disease

Canada
Mayo Clinic
Grifols Biologicals, LLC

Withdrawn

Randomized Placebo Controlled Trial of IVIg in Glycine Receptor Antibody Positive Stiff-person Syndrome

Stiff-Person Syndrome

United States
University of Giessen
Hoffmann-La Roche; Astellas Pharma Inc; Heidelberg University; Aventis Pharmaceuticals

Completed

Immunoregulatory Effects of Immunoglobulin Induction Therapy in Renal Transplant Recipients

Renal Transplantation | Renal Failure, Chronic

Germany
University of Cambridge
University of Oxford

Recruiting

IVIG and Rituximab in Antibody-associated Psychosis - SINAPPS2 (SINAPPS2)

Psychosis | Autoimmune Encephalitis

United Kingdom
National Taiwan University Hospital

Unknown

A Trial to Evaluate the Efficacy of Immunoglobulin Plus Steroid for Prevention of Coronary Artery Abnormalities in Taiwanese Refractory Kawasaki Disease (RAST Study) (RAST)

Kawasaki Disease | Steroid | Immuoglobulin

Taiwan
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States, Canada
Grifols Therapeutics LLC

Completed

Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary Immunodeficiency (KIDS)

Primary Immunodeficiency

United States
National Institute of Allergy and Infectious Diseases...

Completed

An Evaluation of IV Gamma Globulin As a Method to Improve Kidney Transplant Survival in Patients With End-Stage Renal Disease Who Are Highly Sensitized to Transplant Antigens

Kidney Transplantation | End-Stage Renal Disease

United States
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of Two Intradermal Rabies Vaccine Regimens Administered With and Without Human Rabies Immunoglobulin in Subjects ≥ 1 Years of Age

Rabies Infection

Philippines, Thailand
Biotest Pharmaceuticals Corporation

Completed

Pilot Study to Assess the Pharmacokinetics of Intravenous Nabi 5% Hepatitis B Immune Globulin (Boca HBVIg) Used in Combination With Lamivudine for Patients With Hepatitis B Virus (HBV) Associated Liver Disease Undergoing Liver Transplantation

Hepatitis B Virus Associated Liver Disease

United States
Mayo Clinic
Entera Health, Inc

Terminated

Manage Diarrhea in Patients With Multiple Myeloma While Receiving Conditioning Chemotherapy for Autologous SCT

Multiple Myeloma

United States
University of Ulm
Miltenyi Biomedicine GmbH

Recruiting

Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (IVITOC)

CIDP

Germany
St. Louis University
CSL Behring

Terminated

Subcutaneous Ig Maintenance Therapy for Myasthenia Gravis (SIMM)

Myasthenia Gravis

United States
Medical University of Vienna
National Bank of Austria; Biotest Pharma GmbH

Terminated

The Impact of IVIG Treatment on Critical Illness Polyneuropathy and/or Myopathy in Patients With MOF and SIRS/Sepsis (CIPNM)

Polyneuropathies

Austria
Loma Linda University

Terminated

Intravenous Immune Globulin (IVIG) Treatment Protocol in Kidney Transplant Patients

End Stage Renal Disease
Lifefactors Zona Franca, SAS

Unknown

Convalescent Plasma (PC) and Human Intravenous Anti-COVID-19 Immunoglobulin (IV Anti COVID-19 IgG) in Patients Hospitalized for COVID-19.

Coronavirus Disease 2019 (COVID-19)

Colombia
NYU Langone Health
Lupus Research Alliance

Completed

Preventive IVIG Therapy for Congenital Heart Block (PITCH)

Congenital Heart Block | Neonatal Lupus | Autoantibody-associated Heart Block

United States
University of Tennessee

Completed

Human Immune Globulin in Treating Patients With Primary Amyloidosis That is Causing Heart Dysfunction

Multiple Myeloma | Plasma Cell Neoplasm

United States
Rutgers, The State University of New Jersey

Recruiting

Immunoglobulin G Therapy Dose Optimization

Obesity | Immune Deficiency

United States
Hansa Biopharma AB

Recruiting

Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx (ConfIdeS)

Kidney Transplantation in Highly Sensitized Patients

United States
Baxalta now part of Shire

Completed

Comparison of Intravenous and Subcutaneous Administration of IGIV, 10% in Primary Immunodeficiency (PID) Subjects

Primary Immunodeficiency Diseases (PID)

United States
Sheba Medical Center

Recruiting

Anti T-lymphocyte Immunoglobulin With Post Transplant Cyclophosphamide to Prevent GVHD Post Allogeneic Transplantation

Graft Versus Host Disease

Israel
Research Institute of Epidemiology, Microbiology...

Active, not recruiting

Serum 25(OH) Vitamin D and Total Serum Immunoglobulin E Levels in Patients With Pityriasis Alba

Pityriasis Alba

Uzbekistan
Georgetown University
Cangene Corporation

Completed

Evaluating Blood Glucose Levels During Infusion With HepaGam B (HBIG) in Post-liver Transplant Patients

Hepatitis B

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Improving Transplant Options of Highly Sensitized Recipients Using IGIV-C, 10%

Kidney Failure, Chronic

United States
A.O. Ospedale Papa Giovanni XXIII
Aferetica - Italy (BO)

Terminated

Convalescent Antibodies Infusion in Critically Ill COVID 19 Patients

Coronavirus Infection | Pneumonia, Ventilator-Associated

Italy
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Purified Vero Rabies Vaccine

Rabies Virus

United States
Grifols Therapeutics LLC

Completed

A Trial of the Pharmacokinetics, Safety, and Tolerability of Subcutaneous Gamunex® in Primary Immunodeficiency

Immunologic Deficiency Syndrome

United States, Canada
University Hospital Tuebingen
Universität Tübingen

Completed

Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients (IVIG)

Septic Shock | Respiratory Distress Syndrome, Adult

Germany
Medical University of Vienna

Completed

Biseko Versus Albumin in Systemic Inflammatory Response Syndrome (SIRS) Patients

Systemic Inflammatory Response Syndrome

Austria

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