Clinical Trials Sponsored by AstraZeneca Pharmaceuticals" LLC

Total 770 results

Cubist Pharmaceuticals LLC

Completed

Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain

Constipation
Edgemont Pharmaceuticals, LLC

Completed

EDG004 Treatment of Adult Patients With Generalized Anxiety Disorder (GAD)

Generalized Anxiety Disorder (GAD)

United States
Cubist Pharmaceuticals LLC

Completed

Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain

Opioid Induced Constipation
Cubist Pharmaceuticals LLC

Completed

Study of CB-183,315 in Participants With Clostridium Difficile Infection

Diarrhea | Clostridium Difficile Infection

United States, Canada
Cubist Pharmaceuticals LLC

Completed

Study to Evaluate Daptomycin Given During Dialysis and After Dialysis

End-stage Renal Disease | Renal Failure Chronic Requiring Hemodialysis

United States
Cubist Pharmaceuticals LLC

Completed

Safety Study to Evaluate Daptomycin in Non-infected Adults Who Are Either on Hemodialysis or Continuous Ambulatory Peritoneal Dialysis (MK-3009-021)

End-Stage Renal Disease
Cubist Pharmaceuticals LLC

Completed

Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas

Cellulitis

United States
Iroko Pharmaceuticals, LLC

Completed

Study of Diclofenac Capsules to Treat Pain Following Surgery in Children Ages 6 to <17 Years of Age

Pain, Postoperative

United States
Cubist Pharmaceuticals LLC

Terminated

Daptomycin for the Treatment of Infections Due to Gram-Positive Bacteria

Gram-Positive Bacterial Infections
Optimer Pharmaceuticals LLC

Completed

PAR-101/OPT-80 Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD)

Diarrhea | Clostridium Infections

United States, France, United Kingdom, Belgium, Spain, Canada, Germany, Italy, Sweden
Optimer Pharmaceuticals LLC

Completed

OPT-80 in Clostridium Difficile-Associated Diarrhea (CDAD)

Diarrhea

United States
Hikma Pharmaceuticals LLC

Completed

Study of Cemivil® (Imatinib) in Chronic Myeloid Leukemia Patients in Jordan (CCMLJ)

Chronic Myeloid Leukemia, Chronic Phase

Jordan
Cubist Pharmaceuticals LLC

Completed

A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy

Postoperative Ileus

United States
Cubist Pharmaceuticals LLC

Completed

Study Evaluating the Analgesic Efficacy and Safety of ADL5859 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Marathon Pharmaceuticals, LLC

Withdrawn

A Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Investigational Product MP-101 in Subjects With Short Bowel Syndrome Who Have Had an Inadequate Response to Anti-Diarrheals

Short Bowel Syndrome | Short Gut Syndrome | SBS | Short Gut | Short Bowel

United States
Amneal Pharmaceuticals, LLC

Completed

Study to Evaluate the Safety and Bioequivalence of Estradiol Vaginal Inserts, 10 mcg and Vagifem® 10 mcg and Compare to Placebo

Atrophic Vaginitis Due to Menopause

United States
Iroko Pharmaceuticals, LLC

Completed

Open-Label Study of Diclofenac Capsules to Treat Osteoarthritis Pain

Osteoarthritis

United States
Ausio Pharmaceuticals, LLC

Completed

Efficacy and Safety of S-equol on Vasomotor Symptoms in Menopausal Patients

Menopause

United States, Australia
Iroko Pharmaceuticals, LLC

Completed

Study of Indomethacin Capsules to Treat Pain Following Bunionectomy

Other Acute Postoperative Pain

United States
Iroko Pharmaceuticals, LLC

Completed

Study of Diclofenac Capsules to Treat Pain Following Bunionectomy

Other Acute Postoperative Pain

United States
Iroko Pharmaceuticals, LLC

Completed

Study of Naproxen Capsules to Treat Dental Pain

Dental Pain

United States
Ausio Pharmaceuticals, LLC

Completed

Safety and Pharmacokinetic Study of S-Equol in Healthy Volunteers

Healthy

United States
Graceway Pharmaceuticals, LLC

Completed

Safety and Effectiveness Study of Actinic Keratosis Treatment Following Cryosurgery

Actinic Keratosis

United States, Canada
Graceway Pharmaceuticals, LLC

Completed

Follow-up Study to Evaluate Sustained Clearance Rates of Actinic Keratoses up to One Year

Actinic Keratoses
Graceway Pharmaceuticals, LLC

Completed

Safety and Effectiveness Study of Imiquimod Creams for Treatment of Actinic Keratoses (AKs)

Actinic Keratoses

United States
Cognition Pharmaceuticals, LLC

Completed

A Study of C105 on Cognitive Dysfunction in Persons With Multiple Sclerosis

Multiple Sclerosis | Cognition Disorders

United States
Graceway Pharmaceuticals, LLC

Completed

1-Year Follow up to the 1473-IMIQ Study

Keratosis

United States
Graceway Pharmaceuticals, LLC

Completed

Four Week Safety and Efficacy Study With a Topical Gel to Treat Common Warts in Pediatric Subjects

Warts

United States
Graceway Pharmaceuticals, LLC

Completed

Study With a Topical Gel to Treat Common Warts in Adults

Warts

United States
Graceway Pharmaceuticals, LLC

Completed

Twelve Week Safety and Efficacy Study With a Topical Gel to Treat Common Warts in Adults

Warts

United States
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas (KOMET)

Neurofibromatosis 1 | Plexiform Neurofibroma (PN)

United States, Canada, France, Italy, Germany, China, United Kingdom, Spain, Japan, Russian Federation, Australia, Poland, Brazil
AstraZeneca
Merck Sharp & Dohme LLC

Completed

A Study to Characterize the Outcomes of Olaparib Maintenance Monotherapy in Newly Diagnosed BRCAwt Ovarian Cancer (FLAME)

Advanced Ovarian Cancer

United States
AstraZeneca
SCRI Development Innovations, LLC

Completed

A Phase II Trial to Evaluate the Efficacy of AZD6094 (HMPL-504) in Patients With Papillary Renal Cell Carcinoma (PRCC)

Papillary Renal Cell Cancer

United States, Canada, United Kingdom, Spain
Columbia University
AstraZeneca; MedImmune LLC

Terminated

Study to Evaluate the Effects of MEDI6012 on Apolipoprotein B100 Metabolism

Cardiovascular Diseases

United States
MedImmune LLC
AstraZeneca; MedImmune Ltd

Completed

A Study to Assess the Safety and Immunogenicity of the Drug CAT-354 in Healthy Japanese Subjects

Healthy

United States
AstraZeneca
Merck Sharp & Dohme LLC

Recruiting

Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed) (PROceed)

Metastatic Castration-resistant Prostate Cancer

Germany
Merck Sharp & Dohme LLC
AstraZeneca

Recruiting

Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)

Advanced Solid Neoplasms

United States, Argentina, Australia, Canada, Colombia, Denmark, France, Guatemala, Ireland, Israel, Japan, Korea, Republic of, Mexico, Peru, Romania, Russian Federation, Spain, Turkey, United Kingdom, Switzerland, Italy
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

Neurofibromatosis 1 | Neurofibroma Plexiform

China
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer

United States, Italy, Spain, Belgium, Canada, France, Korea, Republic of, United Kingdom, Brazil, Czechia, Turkey, Australia, Chile, Germany, Japan, Netherlands, Slovakia
Alliance Foundation Trials, LLC.
AstraZeneca

Active, not recruiting

CHIO3 Trial: CHemotherapy Combined With Immune Checkpoint Inhibitor for Operable Stage IIIA/B Non-Small Cell Lung Cancer

Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer

United States
SCRI Development Innovations, LLC
AstraZeneca

Completed

Iressa in Poor Performance Status Patients With Previously Untreated Advanced Non-Small Cell Lung Cancer

Lung Cancer
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort)

Metastatic Castration-resistant Prostate Cancer

China
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

Neurofibromatosis Type 1

United States, Spain, Poland, Russian Federation
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN (SPRINKLE)

Neurofibromatosis Type 1

United States, Spain, Germany, Netherlands, Russian Federation, Italy, Japan
AstraZeneca
Merck Sharp & Dohme LLC

Completed

Ph II Study to Evaluate Olaparib With Abiraterone in Treating Metastatic Castration Resistant Prostate Cancer.

Metastatic Castration-resistant Prostate Cancer

Belgium, France, Italy, Netherlands, Poland, United States, Canada, Czechia, Russian Federation, United Kingdom, Spain
Merck Sharp & Dohme LLC
AstraZeneca

Completed

A Combination Therapy Study of MK-2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010)

Locally Advanced or Metastatic Solid Tumors
GTO Pharmaceutical, LLC

Terminated

Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment

Female Sexual Dysfunction | Vulvovaginal Atrophy | Vulvodynia | Dyspareunia | Vestibulodynia | Postmenopausal Symptoms | Arousal Disorders, Sexual | Genito-Pelvic Pain/Penetration Disorder | Female Sexual Arousal Disorder | Sexual Pain Disorders

United States
AstraZeneca
ICON plc

Not yet recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis (MaesTTRo)

Transthyretin Amyloidosis | ATTR-CM | ATTRv-PN | ATTR | ATTR-Mixed | hATTR
AstraZeneca
ICON plc

Recruiting

Observational Study Protocol: LIVER-R (LIVER-R)

Hepatobiliary Cancers

United States, Greece, Puerto Rico, Germany, Italy, France
Advenchen Pharmaceuticals, LLC.

Recruiting

Phase 2 Safety and Efficacy Evaluation of AL8326 in ≥2nd Line SCLC

Small Cell Lung Cancer

United States

Clinical Trials Sponsored by AstraZeneca Pharmaceuticals" LLC

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