Clinical Trials Sponsored by Believe Big

Total 1668 results

Lexent Bio, Inc.

Unknown

Detection of Tumor DNA in Blood Samples From Cancer Patients

Cancer | Tumors

United States
Sophiris Bio Corp

Completed

Intraprostatic PRX302 Injection to Treat Localised Prostate Cancer

Prostate Cancer

United Kingdom, United States
Bio Products Laboratory

Completed

Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases (SCIG03)

Common Variable Immunodeficiency | Primary Immune Deficiency Disorders | X-linked Agammaglobulinaemia | Hyperimmunoglobulin M Syndrome

United States
Bio Products Laboratory

Completed

A Study to Investigate Bio Product Laboratory Ltd (BPL's) Factor X in the Prophylaxis of Bleeding in Children <12 Years

Factor X Deficiency

United Kingdom
Bio Products Laboratory

Completed

A Study Comparing the Pharmacokinetics and Tolerance of D-Gam® to Rhophylac® in Rh-D-negative Healthy Volunteers.

Healthy

United Kingdom
Bio Products Laboratory

Completed

A Comparison of the Pharmacokinetics, Safety and Tolerance of Two Formulations of a Liquid IVIg in Healthy Volunteers

Healthy

United Kingdom
Bio Products Laboratory

Completed

A Study to Investigate the Safety and Efficacy of Replenine®-VF in Haemophilia B Patients Undergoing Major Surgery.

Haemophilia B

United Kingdom
Entera Bio Ltd.

Completed

A Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of Oral PTH (1-34) Formulations in Healthy Subjects

Drug Safety and Bioavailability
BTG International Inc.

Completed

Randomized, Double-Blind, Placebo-Controlled Study: CroFab® vs Placebo for Copperhead Snake Envenomation (Copperhead)

Snake Bites

United States
Takara Bio Inc.

Completed

A Study of TBI-1401(HF10) in Patients With Solid Tumors With Superficial Lesions

Solid Tumor

Japan
AB2 Bio Ltd.

Completed

Therapeutic Use of Tadekinig Alfa in Adult-onset Still's Disease

Still's Disease, Adult-Onset

Germany, France, Switzerland
Sesen Bio, Inc.

Terminated

Study of Proxinium for Treating Patients With Squamous Cell Head and Neck Cancer

Head and Neck Cancer | Head and Neck Neoplasms | Carcinoma, Squamous Cell | Squamous Cell Carcinoma of the Head and Neck | Neoplasms, Squamous Cell | Mouth Neoplasms

United States, Canada
Entera Bio Ltd.

Completed

A Three Stage, Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of Oral PTH (1-34) in Healthy Subjects

Drug Safety

Israel
PT Bio Farma

Completed

Antibody Persistence, Immune Response and Safety After Doses of Pentabio Vaccine

Healthy

Indonesia
BTG International Inc.

Completed

Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance

Neoplasms

Germany
PT Bio Farma

Completed

Evaluation on Immunogenicity and Safety Profile of Trivalent OPV (tOPV Bio Farma)

Healthy

Indonesia
PT Bio Farma

Completed

Safety of Hib Vaccine (Bio Farma)

Healthy

Indonesia
Bio Products Laboratory

Completed

Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.

Primary Immunodeficiency | Wiskott-Aldrich Syndrome | Hypogammaglobulinemia | Common Variable Hypogammaglobulinemia | X-linked Hypogammaglobulinemia | Immunodeficiency With Hyper-IgM

United States
Lotus Bio Inc.

Unknown

Efficacy Evaluation of a Novel Diagnostic Assay Which is the Basis for Seaforia Diagnostic System

Male Fertility

Israel
Ora Bio Ltd.

Unknown

Pilot Study to Evaluate the Safety and Efficacy of Treatment With ORA102 Combined With Avastin (Bevacizumab) Versus Avastin Alone, in Patients With Neovascular Age Related Macular Degeneration (AMD)

Macular Degeneration

Israel
Karo Bio AB

Completed

LDL-Cholesterol Lowering Effect of KB2115 as Add on to Statin

Dyslipidemia

Sweden
Karo Bio AB

Completed

LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe

Hypercholesterolemia

Sweden
Karo Bio AB

Completed

Eprotirome for the Treatment of Dyslipidemia, Efficacy and Safety 12-Week, Phase ii Study to Assess the Safety and Efficacy of KB2115 in Patients With Primary Hypercholesterolemia

Primary Hypercholesterolemia

Sweden
Onze Lieve Vrouwe Gasthuis
Medela AG

Completed

Assessing the Effect of an Additional 5 Minutes Pumping on Milk Output in the First Days After Delivery

Breast Pumping

Netherlands
Rogier Caluwe

Completed

Dose Defining Study for the Administration of Vitamin K2 Supplements in Hemodialysis Patients

Vascular Calcification
Nasser Hanna
Genentech, Inc.

Recruiting

Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)

NSCLC | Lung Cancer

United States
Oana Danciu, MD
Pfizer; Big Ten Cancer Research Consortium

Active, not recruiting

Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer

Metastatic Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Estrogen Receptor Positive Breast Cancer | Progesterone Receptor Positive Tumor

United States
Ajjai Alva, MD
AstraZeneca; Big Ten Cancer Research Consortium

Active, not recruiting

Study of Durvalumab and Guadecitabine in Advanced Kidney Cancer

Kidney Cancer | Clear Cell Renal Cell Carcinoma | Advanced Kidney Cancer

United States
H Scott Boswell
Takeda

Terminated

Study Augmenting TAK-659 Action in Relapsed/Refractory AML by Addition Ofthe Proteasome Inhibitor Ixazomib

AML | AML, Adult

United States
Nasser Hanna
Genentech, Inc.

Terminated

Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung Cancer

NSCLC Stage IV | NSCLC, Recurrent

United States
Palo Alto Veterans Institute for Research
Big Health Inc.

Active, not recruiting

A Pilot Study of Digital Cognitive Behavioral Therapy for Veterans

Insomnia

United States
Viela Bio

Withdrawn

Safety and Tolerability of Inebilizumab, VIB4920, or the Combination in Highly Sensitized Candidates Awaiting Kidney Transplantation From a Deceased Donor

Highly Sensitized Patients on Waiting List for Kidney Transplantation

United States
Viela Bio

Terminated

Treatment and Prevention of Acute Lung Injury (ALI) in Patients With COVID-19 Infection (ALI)

Acute Lung Injury

United States
Viela Bio

Completed

A Phase 1b Study of MEDI4920 in Participants With Adult-onset Rheumatoid Arthritis

Adult Onset Rheumatoid Arthritis

United States, Poland
Bio-Thera Solutions

Recruiting

A Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of the Combination of BAT8008 With BAT1308 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
International Bio service

Not yet recruiting

Bioequivalence Study of Generic Celecoxib 200 mg Capsules

Healthy Volunteer
International Bio service

Not yet recruiting

Bioequivalence Study of Empagliflozin 25 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
International Bio service

Not yet recruiting

Bioequivalence Study of Diacerein 50 mg Capsule in Healthy Thai Volunteers

Healthy Volunteer
Upstream Bio Inc.

Recruiting

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)

Severe Asthma

United States, Canada
Upstream Bio Inc.

Recruiting

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps (VIBRANT)

Chronic Rhinosinusitis With Nasal Polyps

United States
Bio-Thera Solutions

Not yet recruiting

BAT1308 Combined With Platinum-Based Chemotherapy± Bevacizumab For PDL1-Positive (CPS ≥1) Cervical Cancer

Cervical Cancer

China
Inmune Bio, Inc.

Recruiting

Study of INKmune in Patients With mCRPC (CaRe Prostate) (CaRe)

Cancer | Metastatic Castration-resistant Prostate Cancer | mCRPC

United States
Bio-Thera Solutions

Recruiting

A Clinical Trial of BAT4406F Injection in Patients With Neuromyelitis Optica Spectrum Disorders

Optic Neuromyelitis Spectrum Disease

China
Solarea Bio, Inc

Recruiting

SBD121, a Synbiotic Medical Food for RA Management

Rheumatoid Arthritis

Australia, New Zealand
Entera Bio Ltd.

Recruiting

Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous Forteo

Hypoparathyroidism

Israel
Bio-Thera Solutions

Recruiting

Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients

Advanced or Metastatic Solid Tumors

China
Cellf Bio LLC

Recruiting

Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence

Fecal Incontinence

United States
Cellevolve Bio Inc

Not yet recruiting

A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML (ASCEND-JC)

Progressive Multifocal Leukoencephalopathy
RedCloud Bio
Parexel

Recruiting

Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation

Non-small Cell Lung Cancer

United States
Q32 Bio Inc.

Recruiting

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Atopic Dermatitis

United States

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