Clinical Trials Sponsored by Bowel Research UK

Total 468 results

Julia Brown
Pfizer; Arthritis Research UK

Completed

TIght COntrol of Psoriatic Arthritis (TICOPA)

Psoriatic Arthritis

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cancer Research UK

Completed

Hepatitis C Rimantadine and Antiviral Combination Therapy (HepRiACT)

Hepatitis C

United Kingdom
University College, London
Roche Pharma AG; Cancer Research UK

Completed

Erlotinib in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer (TOPICAL)

Lung Cancer

United Kingdom
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Unknown

Radiotherapy & Olaparib in COmbination for Carcinoma of the Oesophagus (ROCOCO)

Carcinoma of the Oesophagus

United Kingdom
Institute of Cancer Research, United Kingdom
Prostate Cancer UK

Recruiting

Molecular Stratification Profiling Protocol in Metastatic Castration Resistant Prostate Cancer (mCRPC) - MAESTRO (MAESTRO)

Castration-resistant Prostate Cancer | Metastatic Prostate Cancer

United Kingdom
Reckitt Benckiser Healthcare (UK) Limited
Premier Research Group plc

Completed

Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars

Pain

United States
University College, London
Roche Pharma AG; Cancer Research UK

Completed

Rituximab in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Follicular Non-Hodgkin's Lymphoma

Lymphoma

New Zealand, United Kingdom, Australia
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Terminated

Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial (DREAMtherapy)

Rectal Cancer

United Kingdom
University of Oxford
Public Health England; Cancer Research UK

Active, not recruiting

Extending the National Health Service (NHS) Breast Screening Age Range (AgeX)

Breast Cancer Mortality

United Kingdom
University College, London
Hoffmann-La Roche; Cancer Research UK

Completed

Bevacizumab And Combination Chemotherapy in Rectal Cancer Until Surgery (BACCHUS)

Rectal Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Arthritis Research UK

Unknown

Acquired Immunodeficiency in ANCA Associated Vasculitis (ACQUIVAS)

Systemic Vasculitis
Queen Mary University of London
AstraZeneca; Cancer Research UK

Terminated

A Study Comparing AZD2014 vs Everolimus in Patients With Metastatic Renal Cancer (ZEBRA)

Metastatic Clear Cell Renal Carcinoma

United Kingdom
Imperial College London
Asthma UK; General Practitioners Research Institute

Not yet recruiting

London Asthma Diagnostics Study (LADS)

Asthma

United Kingdom
Institute of Cancer Research, United Kingdom
Prostate Cancer UK

Recruiting

A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT (PACE-NODES)

Prostate Cancer

United Kingdom
University of Oxford
University of Aberdeen; Arthritis Research UK

Completed

Can Shoulder Arthroscopy Work (CSAW)

Shoulder Impingement Syndrome

United Kingdom
University College, London
University of Oxford; Cancer Research UK

Active, not recruiting

[18F] FDOPA PET Imaging in Glioma: Feasibility Study for PET Guided Brain Biopsy (FIG)

Glioma

United Kingdom
Queen Mary University of London
AstraZeneca; Cancer Research UK

Unknown

PAKT: AZD5363 in Combination With Paclitaxel in Triple-Negative Advanced or Metastatic Breast Cancer (PAKT)

Metastatic Breast Cancer

Korea, Republic of, United Kingdom, Hungary, Georgia, France, Romania
Queen Mary University of London
AstraZeneca; Cancer Research UK

Unknown

A Study of AZD2014 in Combination With Selumetinib in Patients With Advanced Cancers (TORCMEK)

Squamous Cell Lung Cancer | Triple-Negative Breast Cancer | Non-squamous Cell Lung Cancer With KRAS Mutations | Non-squamous Cell Lung Cancer With Wild-type KRAS

United Kingdom
Barts & The London NHS Trust
Cancer Research UK; Amgen

Unknown

Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes (REGIME)

Myelodysplastic Syndrome

United Kingdom
University College, London
Roche Pharma AG; Cancer Research UK

Terminated

WBRT & Erlotinib in Advanced NSCLC and Brain Metastases (TACTIC)

Lung Cancer | Metastatic Cancer

United Kingdom
University of Birmingham
Yorkshire Cancer Research; European Society of Coloproctology; National Institute... and other collaborators

Unknown

GlobalSurg-CovidSurg Week

Covid19 | Surgery | Post-Op Complication
Institute of Cancer Research, United Kingdom
Cancer Research UK; Philips Medical Systems

Withdrawn

Magnetic Resonance Guided High Intensity Focused Ultrasound (MRgHIFU) for Pain Palliation of Bone Metastases (HIFU-Bone)

Cancer | Bone Metastases

United Kingdom
University of Manchester
Cancer Research UK; Centre for Trials Research, Cardiff University

Recruiting

Validation of Tie2 as the First Tumour Vascular Response Biomarker for VEGF Inhibitors: VALTIVE1 (VALTIVE1)

Ovary Cancer

United Kingdom
Paion UK Ltd.
Simbec Research; ORION Clinical Services; Creative Clinical Research GmbH

Completed

Efficacy and Safety of Remimazolam (CNS7056) Compared to Propofol for Intravenous Anesthesia During Elective Surgery

Anesthesia, Intravenous

Germany
University of Oxford
Bayer; Medical Research Council; Abbott; British Heart Foundation; Solvay Pharmaceuticals and other collaborators

Active, not recruiting

ASCEND: A Study of Cardiovascular Events iN Diabetes

Diabetes Mellitus

United Kingdom
University of Oxford
GE Healthcare; Roche Pharma AG; Cancer Research UK; National Institute for Health... and other collaborators

Recruiting

SCOOT: Sample Collection for DART (SCOOT)

Lung Cancer

United Kingdom
TidalSense
National Institute for Health Research, United Kingdom; Innovate UK

Completed

Cardiorespiratory Diagnostic Study (CARES)

Healthy | Bronchiectasis | Anemia | Asthma | Lung Cancer | Interstitial Lung Disease | COPD | Long COVID | Upper Respiratory Disease | Congestive Cardiac Failure

United Kingdom
Instituto Nacional de Cancer, Brazil
Cancer Research UK Cambridge Institute

Unknown

A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer (MEGA)

Breast Neoplasm

Brazil
Professor Saad Shakir
Bayer

Completed

An Observational Post-Authorization Safety Specialist Cohort Event Monitoring Study (SCEM) to Monitor the Safety and Utilization of Rivaroxaban (Xarelto®). (ROSE)

Atrial Fibrillation | Deep Vein Thrombosis | Pulmonary Embolism

United Kingdom
Imperial College London
Engineering and Physical Sciences Research Council, UK

Not yet recruiting

Remote Monitoring in Preschool Wheeze

Respiratory Sounds | Wheezing

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK

Recruiting

Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer (PARTNER)

Breast Cancer

United Kingdom
University College, London
Cancer Research UK; The Brain Tumour Charity

Completed

Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases (HIPPO)

Brain Metastases

United Kingdom
University College, London
Eli Lilly and Company; Cancer Research UK

Terminated

ERCC1 Targeted Trial (ET)

Lung Cancer

United Kingdom
University College, London
Novartis; Cancer Research UK; Janssen Pharmaceutica NV

Not yet recruiting

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer (STAMPEDE2)

Prostate Cancer Metastatic
Liz-Anne Lewsley
Ovarian Cancer Action

Recruiting

Longitudinal Sample Collection to Investigate Adaptation and Evolution of Ovarian High-grade Serous Carcinoma (BriTROC-2)

Ovarian Cancer | Fallopian Tube Cancer | BRCA1 Mutation | BRCA2 Mutation | High Grade Serous Carcinoma | Primary Peritoneal Carcinoma | Carcinosarcoma, Ovarian

United Kingdom
University Hospital Southampton NHS Foundation...
AstraZeneca; Cancer Research UK

Completed

Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP Chemotherapy (ProCAID)

Prostate Cancer

United Kingdom
UCB Biopharma S.P.R.L.
Pharm Research Associates (UK) Ltd.

Completed

Study to Look at How Effective Briviact is as add-on Treatment for Patients With Epilepsy With Partial Onset Seizures (BASE)

Epilepsy With POS With or Without Secondary Generalization

Denmark, Germany, Hungary, Ireland, Italy, Netherlands, Norway, Spain, United Kingdom
Imperial College London
Engineering and Physical Sciences Research Council, UK

Completed

Investigating Outcomes of Lower Limb Trauma

Trauma

United Kingdom
International Centre for Diarrhoeal Disease Research...
Newcastle University, UK

Completed

Influence of Inflammation on Micronutrient Status Assessment

Healthy Infants

Bangladesh
Bangor University
Universita di Verona; North Wales Research Committee, UK

Completed

Intracranial Pressure in Experimental Models of Headache

High Altitude Headache

United Kingdom
Professor David Cunningham
GlaxoSmithKline; Roche Pharma AG; Cancer Research UK

Unknown

Chemotherapy With or Without Bevacizumab or Lapatinib to Treat Operable Oesophagogastric Cancer (ST03)

Oesophagogastric Cancer

United Kingdom
Imperial College London
Cancer Research UK; National Institute for Health Research, United Kingdom

Recruiting

Use of DRS Probe and Tracking for In-vivo Application

Gastrointestinal Cancer

United Kingdom
Imperial College London
Cancer Research UK; National Institute for Health Research, United Kingdom

Not yet recruiting

Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer (IP7-PACIFIC)

Neoplasms | Adenocarcinoma | Prostatic Neoplasms | Prostatic Diseases | Prostate Cancer
University of Nottingham
National Institute for Health Research, United Kingdom; Arthritis Research UK

Completed

Effects of Internet / Web-based Exercises on the Population With Knee Arthritis (Knee OA)

Knee Osteoarthritis | Sleep Disturbance | Knee Pain Chronic

United Kingdom
Barts & The London NHS Trust
Cancer Research UK; UK: Barts Center for Experimental Cancer Medicine (CECM)...

Unknown

A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesothelioma (ADAM)

Malignant Pleural Mesothelioma

United Kingdom
Institute of Cancer Research, United Kingdom
Cancer Research UK; National Institute for Health Research, United Kingdom

Completed

Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome (SIGNIFY)

Li-Fraumeni Syndrome

United Kingdom
Institute of Cancer Research, United Kingdom
Cancer Research UK; National Institute for Health Research, United Kingdom

Recruiting

The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a BRCA Gene Mutation. (GENPET)

Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation

United Kingdom
Macmillan Research Group UK
Center for Applied Research & Education; SMS Medical College and Hospital

Completed

Neurological Outcome in Patients of Traumatic Subarachnoid Haemorrhage

Traumatic Subarachnoid Haemorrhage
University College, London
AstraZeneca; Cancer Research UK; National Institute for Health Research, United...

Completed

Phase I/II Trial of Antagonism of HER in GI Cancer (PANTHER)

Metastatic Colorectal Cancer | Recurrent Colorectal Cancer

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Active, not recruiting

UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies (UKGPCS)

Prostate Cancer

United Kingdom

Clinical Trials Sponsored by Bowel Research UK

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