Clinical Trials Sponsored by Genetics Institute

Total 74731 results

Clinical Genomics Pathology

Completed

Colvera for Detection of Disease Recurrence (NOVA)

Colorectal Adenocarcinoma

United States
Quantum Genomics SA

Completed

Novel Evaluation With QGC001 in Hypertensive Overweight Patients of Multiple Ethnic Origins (NEW-HOPE)

Hypertension

United States
Quantum Genomics SA

Completed

Phase I Study in Healthy Male Subjects Comparing QGC001 to Placebo

Essential Hypertension

France
Sirius Genomics Inc.

Unknown

Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe Sepsis

Septic Shock | Severe Sepsis

United States, Canada, France, United Kingdom
Dalhousie University
Canadian Institutes of Health Research (CIHR); NewLink Genetics Corporation

Completed

Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine (VSVΔG-ZEBOV)

Ebola Viruses
BeiGene
Myriad Genetic Laboratories, Inc.

Completed

The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Participants With Advanced Solid Tumors

Solid Tumors

United States, Spain, United Kingdom, France, Australia, New Zealand
Genetic Immunity
Universitätsklinikum Hamburg-Eppendorf

Completed

Repeated DermaVir Immunizations in HIV-1 Infected Treatment-naïve Patients (GIEU006)

HIV Infection

Germany
AstraZeneca
Myriad Genetic Laboratories, Inc.

Withdrawn

Olaparib Maintenance Treatment Versus Placebo in Patients With PSR Ovarian Cancer Who Are in CR or PR to Platinum-based Chemotherapy and Whose Tumours Carry sBRCAm or HRR-associated Genes Mutations

Platinum Sensitive Relapsed Ovarian Cancer

United States, Korea, Republic of, Peru, United Kingdom, Philippines
Genetic Disease Investigators
Optos, PLC

Completed

Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Multiple Sclerosis | Ehlers-Danlos Syndrome

United States
Dana-Farber Cancer Institute
Translational Breast Cancer Research Consortium; Myriad Genetics, Inc.

Completed

Cisplatin vs Paclitaxel for Triple Negative Breast Cancer

Triple Negative Breast Cancer

United States
Swiss Federal Institute of Technology
United States Agency for International Development (USAID); Quadram Institute... and other collaborators

Completed

IP Peru, Bioavailability of Iron From Potatoes (IPPERU)

Iron-deficiency | Iron Deficiency Anemia | Iron Deficiency (Without Anemia)

Peru
MejoraVisionMD
Maisonneuve-Rosemont Hospital; Retina and Genomics Institute

Recruiting

Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.

Retinitis Pigmentosa | Usher Syndromes | Cone Dystrophy | Retina; Dystrophy

Mexico
Transplant Genomics, Inc.
The Methodist Hospital Research Institute

Terminated

TruGraf® Testing in High-Risk Kidney Transplant Recipients

Kidney Transplant Rejection

United States
zr Pharma & GmbH
Foundation Medicine; Myriad Genetics, Inc.

Completed

Phase 3 Study of Rucaparib as Switch Maintenance After Platinum in Relapsed High Grade Serous or Endometrioid Ovarian Cancer (ARIEL3) (ARIEL3)

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States, Spain, Belgium, Australia, Israel, Germany, France, United Kingdom, Italy, Canada, New Zealand
Functional Genetics Inc.
United States Department of Defense

Unknown

Safety and Pharmacokinetics Study of Human Monoclonal Antibody (FGI-101-1A6)

Influenza

United States
Nail Genesis LLC

Recruiting

Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis

Onychomycosis | Distal Lateral Subungual Onychomycosis

United States
Xenetic Biosciences, Inc.

Terminated

An Endometrial Cancer Study for Women With Recurrent or Persistent Endometrial Cancer

Endometrial Cancer

United States
Genesis Pharma S.A.

Completed

Real-world Evidence Prospective Study on the Effect of Nab-paclitaxel Treatment on the Clinical Outcomes and HRQoL in Patients With MBC in Greece (ABReast)

Metastatic Breast Cancer

Greece
Translational Genomics Research Institute
Eli Lilly and Company

Withdrawn

Study of Capecitabine and Cetuximab as First-Line Therapy in Patients With Metastatic Wild Type Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Colorectal Cancer

Metastatic Colorectal Cancer

United States
MELISA Institute Genomics & Proteomics Research...
Universidad Austral

Unknown

Previfenon® as Chemoprophylaxis of COVID-19 in Health Workers (HERD)

COVID-19 | SARS-CoV2
Dasman Diabetes Institute
Cuban Center for Genetic Engineering and Biotechnology

Completed

Efficacy and Safety of Heberprot-P® in Patients With Advanced Diabetic Foot Ulcer in Dasman Diabetes Institute.

Diabetic Foot
Genesis Medtech Corporation

Recruiting

Clinical Trial in China for Aortic Valve Stenosis

Diseases of Aortic Valve | Aortic Stenosis Disease

China
Genesis Medtech Corporation

Active, not recruiting

SOLUTION Trial in China

Peripheral Arterial Disease | Calcifications Vascular

China
Genesis Athens Clinic

Completed

Intrauterine Antibiotic Infusion in Treating Chronic Endometritis and Restoring Reproductive Dynamics

Chronic Endometritis

Greece
Genesis Pharma S.A.

Completed

A Retrospective Chart Review Study of the Outcomes of 2nd Line Therapy With LEn/Dex in Greek Patients With R/R Multiple MyEloma and the Treatment PatterNs Following Progressive Disease (LEGEND)

Relapsed/Refractory Multiple Myeloma

Greece
zr Pharma & GmbH
Foundation Medicine; Myriad Genetics, Inc.

Completed

A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2) (ARIEL2)

Ovarian Cancer | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer

United States, Spain, Canada, Australia, United Kingdom, France
Interleukin Genetics, Inc.
University of California, San Diego

Unknown

Genetic Polymorphisms Associated With CAD

Coronary Artery Disease
deCODE genetics
Duke University; Henry Ford Health System

Suspended

Veliflapon (DG-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina

Acute Coronary Syndrome

United States
Genesis Research LLC

Recruiting

Investigator Initiated Trial to Further Evaluate the Safety and Efficacy of Trans-perineal Focal Laser Ablation of Localized Prostate Cancer Using High Frequency Micro-ultrasound Imaging

Prostate Cancer | Low-risk or Favorable Intermediate Risk Prostate Cancer Who Are on an Active Surveillance Regimen

United States
Genesis Medtech Corporation

Recruiting

Clinical Trial in China

Diseases of Aortic Valve | Aortic Regurgitation Disease

China
Genesis Medtech Corporation

Active, not recruiting

SOLSTICE Trial in China

Coronary Artery Disease | Calcifications Vascular

China
Genesis Pharma S.A.

Completed

Retrospective and Prospective Study of POmalidomide Plus LoW Dose Dexa Efficacy in RRMM Patients Under Real-Life Conditions (POWERFUL)

Relapse/Refractory Multiple Myeloma

Greece
Genesis Pharma S.A.

Completed

A Multicenter, Prospective, oBservational Study to assEss the Clinical activitY and Impact on symptOm Burden and patieNts' HRQoL of Treatment With trabecteDin in aSTS in a Real World Setting in Greece (beYOND-STS)

Advanced Soft Tissue Sarcoma

Greece
Genesis Health System

Unknown

The Use of Coconut Oil for the Prevention and Treatment of Diaper Dermatitis in the NICU Population

Dermatitis, Contact

United States
Chong Qing Reproducive and Genetic Institute
Merck Sharp & Dohme LLC

Unknown

Effectiveness and Safety Study of Fixed Versus Flexible of Gonadotropin-releasing Hormone Antagonist Protocol (GnRH)

Infertility
Sensor Technology for Deafblind
Central Clinical Hospital under President Affairs; Deaf-Blind Support Foundation... and other collaborators

Completed

Prospective Open Clinical and Genetic Study of Patients With Retinitis Pigmentosa (RU-RP)

Retinitis Pigmentosa | Usher Syndromes

Russian Federation
Spinal Kinetics

Recruiting

M6®-C Artificial Cervical Disc Two-Level IDE Pivotal Study

Cervical Disc Degenerative Disorder

United States
Reproductive & Genetic Hospital of CITIC-Xiangya

Recruiting

Live Birth After Letrozole-stimulated Cycles Versus Hormone Replacement Treatment Cycles for the First Frozen Embryo Transfer in Women With PCOS

PCOS

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Completed

Personal FET in RIF Patients According to Histological Dating of Endometrial of Natural/ Hormone Replacement Cycle

Infertility, Female

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Withdrawn

Study of Value of Dexamethasone Used in Ovulation Induction

Infertility, Female

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Withdrawn

Effect of Intrauterine Injection of HCG on Pregnancy Outcome in Repeated Implantation Failure Patients

Infertility

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Completed

Transcriptomic Profile of Endometrium in Different Histological Dating of Natural Cycle

Infertility, Female

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Completed

A Retrospective Study on the Effect of HBA or HBB Genetic Defects on Early Embryonic Development

Thalassemia,Embryonic Development,Reproductive Sterility and Infertility

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Completed

A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome

Sperm Count, Low | Reproductive Sterility

China
Center for Reproductive an Genetic Health

Unknown

The Effectiveness of Blastocentesis Versus Trophectoderm Biopsy

Abnormal Karyotype

United Kingdom
Razor Genomics
Encore Clinical

Recruiting

Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States, France, Germany
Global Genomics Group, LLC

Unknown

GLOBAL Clinical Study (GLOBAL)

Coronary Artery Disease

United Kingdom, United States, Hungary, Netherlands, Australia, Germany, Poland, Canada, Croatia
Reproductive & Genetic Hospital of CITIC-Xiangya

Recruiting

Recombinant LH Supplementation Timing Strategies (From Day 1 or Day 6) to a Standard GnRH Agonist Long Protocol in Subsequent COS Cycle of Older Patients With Unexpected Poor or Suboptimal Ovarian Response

Infertility,Female

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Recruiting

CLBR Per Initial Cycle With Different Starting Dose in Aged Patients With Poor Ovarian Reservation: 300IU Versus 150IU

Infertility

China
Reproductive & Genetic Hospital of CITIC-Xiangya

Terminated

A Study of Preimplantation Genetic Screening With Next Generation Sequencing Technology on Advanced Age Women

Infertility

China

Clinical Trials Sponsored by Genetics Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mali

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations