Clinical Trials Sponsored by LISCure Biosciences

Total 1894 results

Catalyst Biosciences

Terminated

Screening Study to Identify Patients With Complement Factor I Deficiencies

Previous Diagnosis With a Complement-mediated Disease and/or With Clinical Manifestations Reasonably Associated With Complement Factor I Deficiency

United States
Neurocrine Biosciences

Completed

Open-Label Safety and Tolerability Study of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome

Tourette Syndrome

United States, Puerto Rico
Pyramid Biosciences

Completed

A Study to Evaluate the Skin Irritation Potential of PBI-100 Topical Cream in Healthy Participants

Healthy Volunteers

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Effects of KB295 in Patients With Ulcerative Colitis (UC) on Gut Microbiota Structure and Function

Ulcerative Colitis

Ireland, United States
Flame Biosciences

Withdrawn

FL-101 in Surgically Resectable Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer
Catalyst Biosciences

Terminated

Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders

Factor VII Deficiency | Hemophilia A With Inhibitor | Glanzmann Thrombasthenia

United States, India, Italy, Russian Federation, Ukraine
Catalyst Biosciences

Completed

Study of Coagulation Faction VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With Hemophilia

Hemophilia A | Hemophilia B | Hemophilia A With Inhibitor | Hemophilia B With Inhibitor | Hemophilia A Without Inhibitor | Hemophilia B Without Inhibitor

Bulgaria, Russian Federation
Kaleido Biosciences

Completed

An Observational Clinical Study to Evaluate COVID-19 Symptoms in "Long Hauler" Patients Who Participated in K031-120 or K032-120

COVID-19

United States
Neurocrine Biosciences

Completed

Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome

Tourette Syndrome

United States, Puerto Rico
Hemera Biosciences

Withdrawn

Intravitreal AAVCAGsCD59 for Advanced Dry Age-related Macular Degeneration (AMD) With Geographic Atrophy (GA)

Geographic Atrophy | Dry Age-related Macular Degeneration | Gene Therapy | Intravitreal Injection
Neurocrine Biosciences

Completed

Safety and Tolerability Study of NBI-98854 for the Treatment of Subjects With Tourette Syndrome

Tourette Syndrome

United States
Assembly Biosciences

Terminated

ABI-M201 in Adult Subjects With Mildly-to-Moderately Active Ulcerative Colitis

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Mild

United States, Canada
Assembly Biosciences

Completed

A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)

Chronic Hepatitis B

United States, Canada, Hong Kong, New Zealand, United Kingdom
Assembly Biosciences

Completed

A Study to Evaluate the Mass Balance Absorption and AME of VBR

Chronic Hepatitis B

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Effect of Novel Glycans on Nitrogen Metabolism of the Gut in Healthy Subjects

Healthy

United States
Neurocrine Biosciences

Completed

Safety and Efficacy Study of NBI-98854 in Adults With Tourette Syndrome

Tourette Syndrome

United States
Assembly Biosciences

Completed

A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults

Chronic Hepatitis B

United States
Kaleido Biosciences

Completed

Clinical Food Study to Evaluate the Effect of KB195 on Gut Nitrogen Metabolism in Patients With Urea Cycle Disorders

Urea Cycle Disorders

Switzerland
Assembly Biosciences

Completed

Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of, Taiwan, Australia, Hong Kong, United Kingdom
Asana BioSciences

Terminated

Safety, Preliminary Efficacy and Pharmacokinetics of ASN001 in Metastatic Castrate Resistant Prostate Cancer

Prostate Cancer | Cancer of the Prostate | Neoplasms, Prostate | Prostatic Cancer | Neoplasms, Prostatic | Prostate Neoplasms, Castration-resistant

United States
Translational Biosciences

Completed

Feasibility Study of Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in Patients With Multiple Sclerosis

Multiple Sclerosis

Panama
Neurocrine Biosciences

Completed

A Phase 3 Study of NBI-98854 for the Treatment of Tardive Dyskinesia (KINECT 3)

Tardive Dyskinesia

United States, Canada, Puerto Rico
Catalyst Biosciences

Completed

Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia

Hemophilia A

United States, Belgium, Hungary, Italy, New Zealand, South Africa, Turkey, United Kingdom
Neurocrine Biosciences

Withdrawn

An Exploratory Study of NBI-34060 Capsules and Next Day Functioning

Insomnia

United States
YM BioSciences

Completed

Pharmacokinetic Study of Tesmilifene (YMB1002) Plus Epirubicin and Cyclophosphamide in Metastatic Breast Cancer

Metastatic/Recurrent Breast Cancer

Russian Federation, Georgia, Ukraine
Neurocrine Biosciences

Completed

Safety, Tolerability, and Pharmacokinetics of a Single Dose of NBI-98854 in Subjects With Mild,Moderate, or Severe Hepatic Insufficiency

Safety, Tolerability, and PK of NBI-98854 in Hepatically Impaired Subjects

United States
Epiphany Biosciences

Completed

A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster

Herpes Zoster

United States
Neurocrine Biosciences

Completed

Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of NBI-98854 in Healthy Subjects

Effect of Ketoconazole on the PK of NBI-98854 in Healthy Subjects

United States
Pierian Biosciences

Completed

Chemotherapy Drug Sensitivity Microculture (MiCK) Assay for Apoptosis

Sarcoma, Soft Tissue | Breast Neoplasms | Lung Neoplasms | Ovarian Neoplasms

United States
YM BioSciences

Completed

Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma

Recurrent Diffuse Pontine Gliomas

United States, Canada, Israel
Predictive Biosciences

Completed

Hematuria Evaluation Trial for Subjects With Microscopic or Gross Hematuria to Determine the Absence or Presence of Bladder Cancer

Microscopic or Gross Hematuria

United States
Neurocrine Biosciences

Completed

A Study to Evaluate NBI-6024 in Adult and Adolescent Patients With New Onset of Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Spain, Finland, Canada, France, Czech Republic, Germany, South Africa, United Kingdom
YM BioSciences

Completed

Tesmilifene in Combination With Docetaxel in the Treatment of Metastatic Breast Cancer

Metastatic Breast Cancer

Serbia
YM BioSciences

Completed

Study Evaluating Inhaled AeroLEF Delivered in 4 Aerosol Delivery Devices in Healthy Volunteers (LEF-07)

Healthy
YM BioSciences

Completed

Phase II Study of Inhaled AeroLEF for Analgesia After ACL Knee Surgery (Pain)

Pain | Post Operative Pain

Canada
YM BioSciences

Completed

Study of Single and Multiple Doses of Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Healthy Subjects (LEF-2495)

Healthy

Canada
YM BioSciences

Completed

Study Evaluating Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Normal Healthy Subjects

Healthy

Canada
Neurocrine Biosciences

Terminated

Study Of Indiplon/Placebo With Sertraline In Insomnia Co-Existing With Depression

Depression | Insomnia
TopAlliance Biosciences
Shanghai Junshi Bioscience Co., Ltd.; CTI Clinical Trial and Consulting Services

Recruiting

Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

Metastatic Solid Tumor | Advanced Unresectable Solid Tumor

United States
Shanghai Junshi Bioscience Co., Ltd.
CTI Clinical Trial and Consulting Services; TopAlliance Biosciences, Inc.

Withdrawn

A Clinical Study of TAB006 in Patients With Previously Treated, Advanced Malignancies

Malignancies | Previously Treated, Advanced
Hope Biosciences Stem Cell Research Foundation

Completed

Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome (HBPCOVID02)

Post COVID-19 Syndrome

United States
Hope Biosciences Stem Cell Research Foundation

Active, not recruiting

Randomized Double-Blind Phase 2 Efficacy and Safety of Autologous HB-MSCs vs Placebo for Treatment of Multiple Sclerosis (HBMS01)

Multiple Sclerosis

United States
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

Completed

A Clinical Trial to Determine the Safety and Efficacy of HB-adMSCs to Provide Protection Against COVID-19

COVID-19

United States
Hope Biosciences Stem Cell Research Foundation

Available

Intermediate Size Expanded Access Protocol Using Autologous HB-adMSCs for the Treatment of Parkinson's Disease

Parkinson Disease
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

No longer available

Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for Spinal Cord Injury

Spinal Cord Injuries

United States
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

Completed

A Randomized, Double-Blind, Single Center, Efficacy and Safety Study of Allogeneic HB-adMSCs Against COVID-19.

COVID-19

United States
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

No longer available

Individual Patient Expanded Access IND of HB-adMSCs for Chronic Musculoskeletal Pain.

Chronic Pain

United States
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

No longer available

Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.

Osteo Arthritis Knee | Knee Pain Chronic

United States
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

Withdrawn

A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy (HB-adMSCs) for the Treatment of Alzheimer's Disease

Alzheimer Disease

United States
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

No longer available

Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for the Treatment of Cerebral Palsy

Cerebral Palsy

United States

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