Clinical Trials Sponsored by LoneStar Heart, Inc

Total 274 results

National Heart, Lung, and Blood Institute (NHLBI)
DSM Nutritional Products, Inc.; Mead Johnson Nutrition; Office of Research on...

Unknown

DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study)

Insulin Resistance | Pre-Eclampsia | Overweight and Obesity | Diabetes, Gestational | Hypertension in Pregnancy

United States
Medical College of Wisconsin
National Heart, Lung, and Blood Institute (NHLBI); University of Wisconsin,... and other collaborators

Recruiting

Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise

Sudden Infant Death | Congenital Heart Disease | Pregnancy Loss | Gastroschisis | Fetal Death | Brugada Syndrome | High Risk Pregnancy | Stillbirth | Long QT Syndrome | Fetal Demise | Birth Defect | Twin Monochorionic Monoamniotic Placenta | Twin Twin Transfusion Syndrome | Fetal Hydrops | Fetal Arrhythmia | Intrauterine... and other conditions

United States
HeartFlow, Inc.
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Baim Institute for Clinical Research and other collaborators

Completed

Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography (DeFACTO)

Coronary Artery Disease

United States
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); OCHIN, Inc.; Kaiser Foundation...

Completed

Assessing a Medicaid Randomized Insurance Experiment Within Community Clinics (AMRIC)

Cardiovascular Disease | Cancer
John Sapp
Canadian Institutes of Health Research (CIHR); Nova Scotia Health Authority; Abbott... and other collaborators

Active, not recruiting

Antiarrhythmics or Ablation for Ventricular Tachycardia 2 (VANISH2)

Ventricular Tachycardia (VT)

Canada, United States, France
Indiana University
National Heart, Lung, and Blood Institute (NHLBI); University of California... and other collaborators

Not yet recruiting

SHADES Mechanistic Trial (SHADES)

Heart Diseases | Cardiovascular Diseases | Coronary Artery Disease | Stroke | Sleep Disorder | Insomnia | Sleep Disturbance | Metabolic Disease | Autonomic Dysfunction | Insomnia Chronic | Systemic Inflammatory Response | Insomnia, Primary

United States
University of Utah
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Nursing... and other collaborators

Completed

Facilitating Patient Communication During Noninvasive Ventilation

Noninvasive Ventilation | Speech Intelligibility

United States
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.

Left Ventricular Diastolic Dysfunction

United States
St George's, University of London
British Heart Foundation; St. Bartholomew's Hospital; Cardiac Risk in the Young

Completed

Training-induced Increased Left Ventricular Trabeculation (MARATHON)

Athletes Heart | Left Ventricular Hypertrabeculation

United Kingdom
St. Jude Children's Research Hospital
Children's Hospital of Philadelphia; National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Dose-Escalation Study Of A Self Complementary Adeno-Associated Viral Vector For Gene Transfer in Hemophilia B

Hemophilia B

United States, United Kingdom
Tallikut Pharmaceuticals, Inc.
Massachusetts General Hospital; Icahn School of Medicine at Mount Sinai; University... and other collaborators

Completed

Phase 2 Study in Vascular Inflammation on Patients After an Acute Coronary Syndrome Event

Acute Coronary Syndrome

United States
University Hospital Heidelberg
The German Heart Foundation; Apple Inc.; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

activeDCM - Interventional Clinical Trial of Individualized Activity and Exercise Programs to Improve Outcome in Dilated Cardiomyopathy Guided by Longitudinal Biosensing With Apple Watch (ACTIVE-DCM)

Heart Failure | Cardiomyopathy, Dilated

Germany
Ascension South East Michigan
Fujirebio Diagnostics, Inc.; International Association of Heat and Frost Insulators... and other collaborators

Terminated

Mesothelioma Early Detection by VOCs (MED-VOC)

Pleural Mesothelioma | Asbestos Exposure | Pleural Plaque

United States
Longeveron Inc.
The University of Texas Health Science Center, Houston; National Heart, Lung... and other collaborators

Recruiting

Evaluation of Lomecel-B™ Injection in Patients With Hypoplastic Left Heart Syndrome (HLHS): A Phase IIb Clinical Trial. (ELPIS II)

Hypoplastic Left Heart Syndrome

United States
Adrian Hernandez
Massachusetts General Hospital; Mayo Clinic; National Heart, Lung, and Blood... and other collaborators

Completed

Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF (INDIE-HFpEF)

Heart Failure

United States
Kaiser Permanente
National Heart, Lung, and Blood Institute (NHLBI); Oregon Health and Science... and other collaborators

Completed

Dissemination of CVD Risk Factor Treatment Among Diabetic Patients in Safety Net Clinics (ALL)

Cardiovascular Diseases | Diabetes Mellitus
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Evaluating Control of Hypertension - Effect of Social Determinants (ECHOES)

Hypertension

United States
Molecular Targeting Technologies, Inc.
National Heart, Lung, and Blood Institute (NHLBI); Yale University; University... and other collaborators

Completed

Study of 99mTc-glucarate to Detect Acute Coronary Syndrome in Chest Pain Patients.

Acute Coronary Syndrome

United States
Baystate Medical Center
National Heart, Lung, and Blood Institute (NHLBI); University of Illinois at... and other collaborators

Withdrawn

The Impact of Interprofessional Training to Improve the Uptake of Noninvasive Ventilation in Patients Hospitalized With Severe COPD Exacerbation (COPD-NIV)

Copd

United States
Institute for Clinical Evaluative Sciences
Heart and Stroke Foundation of Ontario; The Ontario Spor Support Unit; CorHealth... and other collaborators

Recruiting

Using Big Data to Conduct Innovative Cardiovascular Clinical Trials

Cardiovascular Diseases | Dyslipidemias | Cardiovascular Risk Factor

Canada
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI); Clinical Trials in Organ...

Completed

Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients

Heart Transplant

United States
National Institute of Allergy and Infectious Diseases...
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults (REPRIEVE)

Cardiovascular Diseases | HIV Infections

Brazil, Spain, United States, Puerto Rico, Haiti, Zimbabwe, Botswana, South Africa, Thailand, Uganda, India, Peru, Canada
Children's Hospital of Philadelphia
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health (NIH) and other collaborators

Completed

West Philadelphia Controls Asthma (WPCA)

Childhood Asthma | Community Health Workers

United States
Syntrix Biosystems, Inc.
Johns Hopkins University; Mayo Clinic; National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

Myelodysplastic Syndromes

United States
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute; National Heart, Lung, and Blood... and other collaborators

Completed

INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure (INVESTED)

Myocardial Infarction | Heart Failure

United States, Canada, Puerto Rico
ABDULZAHRA HUSSAIN
King's College Hospital NHS Trust; Spire, Inc.; Heart of England NHS Trust; The... and other collaborators

Completed

Revisional Surgery After 925 OAGB[One Anastomosis Gastric Bypass] Operations Retrospective Cohort Study of the UK MGB/OAGB Collaborative Group.

Morality | Revisions After MGB/OAGB | Morbidities
Sarepta Therapeutics, Inc.
University College, London; Catholic University of the Sacred Heart; University... and other collaborators

Completed

Phase I/II Study of SRP-4053 in DMD Patients

Duchenne Muscular Dystrophy

United Kingdom, United States, France, Italy
Lund University
The Swedish Research Council; Region Skane; Swedish Heart Lung Foundation; Swedish... and other collaborators

Recruiting

Carotid Plaque Imaging Project (CPIP) (CPIP)

Atherosclerosis | Atherosclerotic Plaque

Sweden
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI); Rush University Medical... and other collaborators

Completed

Genetics Informatics Trial (GIFT) of Warfarin to Prevent DVT (GIFT)

Thromboembolism

United States
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal; Royal Victoria Hospital, Canada; Queen Elizabeth II Health Sciences Centre and other collaborators

Completed

A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA)

Hypertriglyceridemia

Canada
Karolinska Institutet
Swedish Heart Lung Foundation; Ministry of Health and Social Affairs, Sweden; Swedish Association of Local Authorities and Regions and other collaborators

Unknown

Survival Study After Out-of-hospital Cardiac Arrest (SAMS)

Out-of-Hospital Cardiac Arrest

Sweden
Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR); Population Health Research Institute and other collaborators

Not yet recruiting

Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy (TaRGET)

Arrhythmogenic Right Ventricular Cardiomyopathy | Arrhythmogenic Cardiomyopathy

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR); University of Leipzig; Heart and... and other collaborators

Completed

Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Older (SCREEN-AF)

Hypertension | Atrial Fibrillation

Canada, Germany
Massachusetts General Hospital
Washington University School of Medicine; National Heart, Lung, and Blood Institute... and other collaborators

Completed

Multicenter Study to Rule Out Myocardial Infarction by Cardiac Computed Tomography (ROMICAT-II)

Myocardial Infarction | Acute Coronary Syndrome | Unstable Angina Pectoris

United States
Children's Hospital of Philadelphia
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); Boston Children's Hospital and other collaborators

Recruiting

Eliminating Monitor Overuse Trial (EMO Trial)

Bronchiolitis Acute Viral

United States, Canada
Wake Forest University Health Sciences
Johns Hopkins University; The University of Texas Health Science Center, Houston and other collaborators

Recruiting

Long-term Effectiveness of the Antiobesity Medication Phentermine (LEAP)

Obesity | Lifestyle, Healthy | Obesity; Drug

United States
Dana-Farber Cancer Institute
Johns Hopkins University; Washington University School of Medicine; National... and other collaborators

Completed

Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell Disease

Sickle Cell Disease

United States
University College, London
National Institute for Cardiovascular Outcomes Research; NICOR/MINAP, the United... and other collaborators

Completed

MI Mortality Risk and Between-hospital Risk Variation in the United Kingdom and Sweden

Acute Myocardial Infarction

United Kingdom, Sweden
Swedish Heart Lung Foundation
The Council for Medical Health Care Research in South Sweden; The Malmö University... and other collaborators

Completed

Trial of an Interactive CD-Program on 6 Months Readmission Rate in Patients With Heart Failure

Heart Failure

Sweden
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI); Fogarty International Center... and other collaborators

Recruiting

Effects of a Package of Evidence-based Interventions and Implementation Strategies Based on WHO PEN for People Living With HIV and Cardio-metabolic Conditions in Lusaka, Zambia (TASKPEN UH3)

HIV | Non Communicable Diseases

Zambia
I.C. Van Gelder
Bayer; AstraZeneca; Boehringer Ingelheim; Boston Scientific Corporation; Medtronic; Abbott Medical Devices and other collaborators

Completed

Routine Versus Aggressive Upstream Rhythm Control for Prevention of Early Atrial Fibrillation in Heart Failure (RACE 3)

Atrial Fibrillation

United Kingdom, Netherlands
Baxalta now part of Shire
National Heart, Lung, and Blood Institute (NHLBI); SAIC-Frederick, Inc.; Cato... and other collaborators

Completed

A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease

Sickle Cell Disease

United States
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI); GlaxoSmithKline; University... and other collaborators

Completed

VIR-7831 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

COVID-19

United States, Denmark, Poland, Singapore, Spain, Switzerland, Uganda, United Kingdom
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI); University of Alabama at... and other collaborators

Completed

Task-shifted Adaptation of the WHO-PEN Intervention to Address Cardio-metabolic Complications in People Living With HIV in Zambia (TASKPEN)

HIV | Non Communicable Diseases

Zambia
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT (DEXTERITY-AFP)

Thrombosis, Deep Vein | Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI); Gilead Sciences; University... and other collaborators

Completed

ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19 (TESICO)

Covid19

United States
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT (DEXTERITY-SCI)

Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
RTI International
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); Northwestern University and other collaborators

Enrolling by invitation

Continuation of the nuMoM2b Heart Health Study (nuMoM2b-HHS2)

Cardiovascular Diseases

United States
Odense University Hospital
Department of Cardiology, Odense University Hospital, Odense, Denmark.; Health... and other collaborators

Completed

Atrial Fibrillation, Prevention and Rehabilitation

Atrial Fibrillation | Rehabilitation | Prevention

Denmark
St. Justine's Hospital
University of Maryland, College Park; Tokyo Women's Medical University; Tokyo... and other collaborators

Enrolling by invitation

The Medical Management in Patients Exposed to Weapons of Mass Destruction (CBRNEObs)

Acute Respiratory Distress Syndrome | Medical Emergencies | Distress Respiratory Syndrome | Chemical Injury | Chemicals; Intoxication

Canada, France, Japan, United States

Clinical Trials Sponsored by LoneStar Heart, Inc

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