Clinical Trials Sponsored by Motif Bio

Total 2369 results

Bio-Thera Solutions

Active, not recruiting

A Randomized, Double-blind, Single-dose, Two-arm Parallel Study to Compare the Pharmacokinetics and Safety of BAT1806 Prefilled Subcutaneous Injection With RoActemra® in Healthy Chinese Male Subjects

Healthy Men

China
Upstream Bio Inc.

Completed

Safety and Biologic Impact (Pharmacodynamics) of Repeated Injections and Increasing Amounts of UPB-101 in Asthmatics

Asthma

United Kingdom
Bio-Thera Solutions

Completed

Comparative Study of BAT2506 With Simponi® in Participants With Active Psoriatic Arthritis

Psoriatic Arthritis

China
Bio-Thera Solutions

Completed

Comparative Study to Evaluate the Pharmacokinetics of BAT2306 vs Cosentyx® in Healthy Subjects

Psoriasis

China
Bio-Thera Solutions

Completed

Evaluate the Pharmacokinetics of BAT2606 Injection in Healthy Chinese Male Subjects

Severe Asthma

China
Gritstone bio, Inc.

Completed

Study of GRT-R910 COVID-19 Boost Vaccine in Healthy Volunteers

COVID-19

United Kingdom
Nuvation Bio Inc.

Terminated

Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors

Glioma | Breast Cancer | Glioblastoma | Advanced Breast Cancer | Prostate Cancer | Metastatic Breast Cancer | Recurrent Glioblastoma | Breast Carcinoma | Castration-resistant Prostate Cancer | Prostate Neoplasm | Cancer of the Prostate | Prostatic Cancer | Glioma, Malignant | Cancer of Breast | Malignant Tumor of Breast and other conditions

United States
Tela Bio Inc

Completed

Ventral Hernia Study Using OviTex Reinforced Bioscaffold

Hernia, Ventral

United States
Bio-Thera Solutions

Terminated

Clinical Trial of BAT8003 (for Injection) for Patients With Advanced Epithelial Cancer

Advanced Solid Cancer

China
Qlaris Bio, Inc.

Completed

A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101

Ocular Hypertension | Glaucoma | Glaucoma Congenital | Sturge-Weber Syndrome (SWS)

United States
Sesen Bio, Inc.

Terminated

Study of the Safety of VB6-845 in Patients With Advanced Solid Tumours of Epithelial Origin

Neoplasms, Glandular and Epithelial

Russian Federation, Georgia
AmMax Bio, Inc.

Completed

A Study of AMG 820 in Subjects With Advanced Solid Tumors

Cancer | Advanced Solid Tumors | Oncology | Tumors | Advanced Malignancy | Oncology Patients

United States
Gritstone bio, Inc.

Terminated

Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer

Colorectal Neoplasms | Colonic Neoplasms

United States
CKD Bio Corporation

Completed

Safety and Efficacy of CKDB-501B in Subjects With Moderate-to-severe Glabellar Lines

Glabellar Lines

Korea, Republic of
Nuvation Bio Inc.

Withdrawn

Study of NUV-422 in Combination With Enzalutamide in Patients With mCRPC

Prostate Cancer | Prostate Neoplasm | Cancer of the Prostate | Prostatic Cancer | Castrate Resistant Prostate Cancer | Cancer of Prostate | Castration Resistant Prostatic Cancer | Castration Resistant Prostatic Neoplasms

United States
PT Bio Farma

Completed

Safety and Immunogenicity Following Recombinant Hepatitis B (Bio Farma) Vaccine in Adults & Children

Hepatitis B

Indonesia
Q32 Bio Inc.

Completed

Single and Multiple Ascending Dose Study of ADX-914 in Healthy Adult Volunteers

Safety Issues

Australia
PT Bio Farma

Completed

Safety Profile Following Inactivated COVID-19 Vaccine in Healthy Adults Aged >18 Years in Indonesia

Safety Issues

Indonesia
Adicet Bio, Inc

Enrolling by invitation

Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells

Lymphoma, Follicular | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal B-cell Lymphoma

United States
Bio-Thera Solutions

Completed

Comparative Study of BAT1806 to RoActemra® in Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate

Rheumatoid Arthritis

China
Atox Bio Ltd

Terminated

Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury

Acute Kidney Injury | Peritonitis | Necrotizing Soft Tissue Infection

United States, France
Bio-Thera Solutions

Completed

A Phase I Clinical Trial of BAT5906 Injection in Patients With Wet Age-related Macular Degeneration

Age-related Macular Degeneration

China
Bio-Thera Solutions

Completed

Comparative Study to Evaluate the Pharmacokinetics of BAT2206 vs Stelara® in Healthy Subjects

Psoriasis

China
Atox Bio Ltd

Completed

Evaluation of Safety, PK and Immunomodulatory Effects of AB103 in Necrotizing Soft Tissue Infections Patients

Necrotizing Soft Tissue Infections

United States
Goldfinch Bio, Inc.

Terminated

A Study to Understand the Genetics and Clinical Course of Focal Segmental Glomerulosclerosis (FSGS), Treatment-Resistant Minimal Change Disease (TR-MCD), and Diabetic Nephropathy (DN)

Diabetic Nephropathies | Glomerulosclerosis, Focal Segmental | Minimal Change Disease

United States
Translate Bio, Inc.

Unknown

Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis (RESTORE-CF)

Cystic Fibrosis

United States
PreDxion Bio, Inc.

Unknown

Feasibility Study of MicroKine Dx System in Critically-ill Pediatric Patients.

Multiple Organ Failure
Goldfinch Bio, Inc.

Completed

FIH Ph 1 Study of TRPC5 Channel Inhibitor GFB-887 in Healthy Subjects

Healthy Volunteers

United States
Xequel Bio, Inc.

Terminated

A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer

Diabetic Foot Ulcers

United States, Canada, Hungary, India, Poland
Takara Bio Inc.

Completed

A Study of Combination With TBI-1401(HF10) and Ipilimumab in Japanese Patients With Unresectable or Metastatic Melanoma

Melanoma Stage IV | Melanoma Stage III

Japan
GID BIO, Inc.

Completed

Adipose-derived SVF for the Treatment of Knee OA

Osteoarthritis (OA)

United States
PT Bio Farma

Completed

Safety and Immunogenicity of Vi-DT Typhoid Conjugate Vaccine in Indonesian Adults, Adolescents, Children and Infants

Safety Issues | Immunogenicity

Indonesia
Provention Bio, Inc.

Completed

A Study to Evaluate the Safety of PRV-300 in Adult Subjects With Moderately to Severely Active Ulcerative Colitis (PULSE)

Ulcerative Colitis

Georgia, Moldova, Republic of, Ukraine
Bio Sidus SA

Completed

Pharmacokinetic/Pharmacodynamic Study of 3 Subcutaneous Single Dose Epoetin Alfa Formulations in Healthy Volunteers

Anemia
Bio-Thera Solutions

Unknown

The Efficacy and Safety of BAT8001 Injection for the Treatment of HER2-positive Advanced Breast Cancer

HER2-positive Advanced Breast Cancer

China
PT Bio Farma

Completed

Immunogenicity & Safety of Bio Farma's Measles-Rubella (MR) Vaccine in Indonesian Infants (Bridging Study)

Measles | Congenital Rubella Infection

Indonesia
Bio-Thera Solutions

Unknown

A Phase I Clinical Trial of BAT1306 and BAT8001 Injection in Patients With Solid Tumor

Solid Tumor

China
GRI Bio, Inc.

Terminated

Trial to Examine the Effect of Two Doses of GRI-0621 in Patients With Chronic Liver Disease (GRI-201)

Chronic Liver Disease

South Africa
PT Bio Farma

Completed

Safety and Immunogenicity of Rotavirus (Bio Farma) Vaccine in Adults, Children & Neonates

Safety Issues

Indonesia
PT Bio Farma

Completed

Protectivity and Safety of Quadrivalent Influenza HA Vaccine in Indonesian Population

Safety Issues

Indonesia
Entera Bio Ltd.

Completed

Oral PTH(1-34) PK and PD Study in Patients With Hypoparathyroidism

Hypoparathyroidism

Israel
GID BIO, Inc.

Completed

Adipose-derived SVF for Treatment of Alopecia

Androgenetic Alopecia

United States
Sophiris Bio Corp

Completed

Transperineal Intraprostatic Injection of PRX302 Under Ultrasound Guidance for Management of Prostatic Hyperplasia (TRIUMPH-1)

Benign Prostatic Hyperplasia

Canada
Sophiris Bio Corp

Completed

PSA-Activated PSA-PAH1 for Locally Recurrent Prostate Cancer

Prostate Cancer

United States
Bio-Thera Solutions

Completed

Study of Bevacizumab(BAT1706) and Comparators in Healthy Subjects

NSCLC

New Zealand
Bio Shai Ltd.

Unknown

Study for the Early Diagnosis of Parkinson's Disease

Parkinson's Disease, Idiopathic

Israel, Italy
PT Bio Farma

Completed

Safety and Immunogenicity of Vi-DT Typhoid Conjugate Vaccine (Bio Farma) in Adults and Children (Phase I)

Safety Issues

Indonesia
DongKoo Bio & Pharma

Unknown

Phase I Drug-drug Interaction of Omega-3 and Atorvastatin

Hyperlipidemia, Hypertriglyceridemia

Korea, Republic of
Bio Products Laboratory

Completed

An Open Study to Investigate the Safety and Efficacy of Optivate® in Haemophilia A Patients Undergoing Surgery.

Haemophilia A

Poland, United Kingdom
Bio Products Laboratory

Completed

A Study to Compare the Pharmacokinetics and Safety of Optivate® and Haemate P® in Patients With Von Willebrand Disease.

vonWillebrand's Disease

Israel

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